Cocaine, not morphine, causes the generation of reactive oxygen species and activation of NF-κB in transiently cotransfected heart cells

Cardiovascular Toxicology

Volumn 3, Issue 2, 2003, Pages 141-151

  Hargrave, Barbara Y ^a   Tiangco, David A ^a   Lattanzio, Frank A ^b   Beebe, Stephen J ^b,c  

^a OLD DOMINION UNIVERSITY   (United States)

^b EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^c CENTER FOR PEDIATRIC RESEARCH   (United States)

Author keywords

Cocaine; Free radicals; Morphine; NF B

Indexed keywords

ACETYLCYSTEINE; COCAINE; DICHLORODIHYDROFLUORESCEIN DIACETATE; FREE RADICAL; GLUTATHIONE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MORPHINE; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID; NARCOTIC AGENT;

ANIMAL CELL; ARTICLE; BIOLUMINESCENCE; CELL STIMULATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GENE ACTIVITY; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; REPORTER GENE; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM;

ANIMALIA;

ACETYLCYSTEINE; ANIMALS; CELLS, CULTURED; COCAINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICALS; GENES, REPORTER; GLUTATHIONE; MORPHINE; MYOCYTES, CARDIAC; NARCOTICS; NF-KAPPA B; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; THIOCTIC ACID; TRANSFECTION;

EID: 0642311137     PISSN: 15307905     EISSN: None     Source Type: Journal    
DOI: 10.1385/CT:3:2:141     Document Type: Article

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