Synthesis, conformational analysis and free radical scavenging activity of some new spiropyranoquinolinones

Chemical and Pharmaceutical Bulletin

Volumn 51, Issue 5, 2003, Pages 522-529

  Panteleon, Vassiliki ^a   Marakos, Panagiotis ^a   Pouli, Nicole ^a   Mikros, Emmanuel ^a   Andreadou, Ioanna ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

1,1 diphenyl 2 picrylhydrazyl (DPPH); Conformation; Pyranoquinolinone; Radical scavenging effect

Indexed keywords

3 [5'' AMINOSPIRO(CYCLOPENTANE 1',2''(2''H)[1]BENZOPYRAN 6'' YL)]PROPEN 2 OIC ACID; 3 [5'' NITROSPIRO(CYCLOPENTANE 1',2''(2''H)[1]BENZOPYRAN 6'' YL)]PROPEN 2 OIC ACID; 3',4' DIHYDRO 4' HYDROXY 5' NITROSPIRO[CYCLOPENTANE 1,2'(2'H)[1]BENZOPYRAN] 6' ACETAMIDE; 3',4' DIHYDRO 4' OXOSPIRO[CYCLOHEPTANE 1,2'(2'H)[1]BENZOPYRAN] 6' ACETAMIDE; 3',4' DIHYDRO 4' OXOSPIRO[CYCLOHEPTANE 1,2'(2'H)[1]BENZOPYRAN] 6' AMINE; 3',4' DIHYDRO 4' OXOSPIRO[CYCLOHEXANE 1,2'(2'H)[1]BENZOPYRAN] 6' ACETAMIDE; 3',4' DIHYDRO 4' OXOSPIRO[CYCLOHEXANE 1,2'(2'H)[1]BENZOPYRAN] 6' AMINE; 3',4' DIHYDRO 4' OXOSPIRO[CYCLOPENTANE 1,2'(2'H)[1]BENZOPYRAN] 6' ACETAMIDE; 3',4' DIHYDRO 4' OXOSPIRO[CYCLOPENTANE 1,2'(2'H)[1]BENZOPYRAN] 6' AMINE; 3',4' DIHYDRO 5' NITRO 4' OXOSPIRO[CYCLOHEPTANE 1,2'(2'H)[1]BENZOPYRAN] 6' ACETAMIDE; 3',4' DIHYDRO 5' NITRO 4' OXOSPIRO[CYCLOHEXANE 1,2'(2'H)[1]BENZOPYRAN] 6' ACETAMIDE; 3',4' DIHYDRO 5' NITRO 4' OXOSPIRO[CYCLOPENTANE 1,2'(2'H)[1]BENZOPYRAN] 6' ACETAMIDE; 3',4' DIHYDRO 6' NITROSPIRO[CYCLOHEPTANE 1,2'(2'H)[1]BENZOPYRAN] 4' ONE; 4 [(2 ETHYNYLTRICYCLO[3,3,1,1 3,7]DECAN 2 YL)OXY] 2 NITRO ACETAMIDE; 5' NITROSPIRO[CYCLOHEPTANE 1,2'(2'H)[1]BENZOPYRAN] 6' AMINE; 5' NITROSPIRO[CYCLOHEXANE 1,2'(2'H)[1]BENZOPYRAN] 6' AMINE; 5' NITROSPIRO[CYCLOPENTANE 1,2'(2'H)[1]BENZOPYRAN] 6' ACETAMIDE; 5' NITROSPIRO[CYCLOPENTANE 1,2'(2'H)[1]BENZOPYRAN] 6' AMINE; 5' NITROSPIRO[TRICYCLO[3,3,1,1 3,7]DECANE 2,2'(2'H)[1]BENZOPYRAN] 6' ACETAMIDE; 5' NITROSPIRO[TRICYCLO[3,3,1,1 3,7]DECANE 2,2'(2'H)[1]BENZOPYRAN] 6' AMINE; 6' IODO 5' NITROSPIRO[CYCLOHEPTANE 1,2'(2'H)[1]BENZOPYRANE]; 6' IODO 5' NITROSPIRO[CYCLOHEXANE 1,2'(2'H)[1]BENZOPYRANE]; 6' IODO 5' NITROSPIRO[CYCLOPENTANE 1,2'(2'H)[1]BENZOPYRANE]; 9',10' DIHYDRO 9',10' DIHYDROXYSPIRO[CYCLOPENTANE 1,8'(8'H)PYRAN[2,3 H]QUINOLIN] 2'(1'H)ONE; PYRAN DERIVATIVE; QUINOLINE DERIVATIVE; SCAVENGER; SPIRO COMPOUND; SPIRO(CYCLOPENTANE 1,8'(8'H)PYRAN[2,3 H]QUINOLIN) 2' (1'H)ONE; UNCLASSIFIED DRUG; UNINDEXED DRUG; 1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; PICRIC ACID; QUINOLONE DERIVATIVE;

ARTICLE; CHEMICAL INTERACTION; DRUG ACTIVITY; DRUG CONFORMATION; DRUG CONJUGATION; DRUG SYNTHESIS; SUBSTITUTION REACTION; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; THIN LAYER CHROMATOGRAPHY;

CHROMATOGRAPHY, THIN LAYER; FREE RADICAL SCAVENGERS; HYDROGEN BONDING; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PICRATES; QUINOLONES; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0642309881     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.51.522     Document Type: Article

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