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Volumn 90, Issue 6, 2003, Pages 1054-1060

Blockade of GPIIb/IIIa by eptifibatide and tirofiban does not alter tissue factor induced thrombin generation in human endotoxemia

Author keywords

Coagulation activation; Endotoxemia; Eptifibatide; Randomized controlled trial; Tirofiban

Indexed keywords

BIOCHEMICAL MARKER; D DIMER; ENDOTOXIN; EPTIFIBATIDE; FIBRINOGEN RECEPTOR ANTAGONIST; INTERLEUKIN 6; MESSENGER RNA; PLACEBO; PLASMIN ANTIPLASMIN COMPLEX; PROTHROMBIN; PROTHROMBIN FRAGMENT 1 + 2; THROMBIN; THROMBIN ANTITHROMBIN COMPLEX; THROMBOPLASTIN; TIROFIBAN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 0348163666     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/th03-04-0233     Document Type: Article
Times cited : (19)

References (47)
  • 2
    • 0034971291 scopus 로고    scopus 로고
    • A cell-based model of hemostasis
    • Hoffman M, Monroe DM, III. A cell-based model of hemostasis. Thromb Haemost 2001; 85: 958-65.
    • (2001) Thromb Haemost , vol.85 , pp. 958-965
    • Hoffman, M.1    Monroe III, D.M.2
  • 3
    • 0029914728 scopus 로고    scopus 로고
    • Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/human chimeric 7E3 antibody. Potential implications for the effect of c7E3 Fab treatment on acute thrombosis and "clinical restenosis"
    • Reverter JC, Beguin S, Kessels H, et al. Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/human chimeric 7E3 antibody. Potential implications for the effect of c7E3 Fab treatment on acute thrombosis and "clinical restenosis". J Clin Invest 1996; 98: 863-74.
    • (1996) J Clin Invest , vol.98 , pp. 863-874
    • Reverter, J.C.1    Beguin, S.2    Kessels, H.3
  • 4
    • 0018547288 scopus 로고
    • Exposure of platelet fibrinogen receptors by ADP and epinephrine
    • Bennett JS, Vilaire G. Exposure of platelet fibrinogen receptors by ADP and epinephrine. J Clin Invest 1979; 64: 1393-401.
    • (1979) J Clin Invest , vol.64 , pp. 1393-1401
    • Bennett, J.S.1    Vilaire, G.2
  • 5
    • 0020320790 scopus 로고
    • Adenosine diphosphate induces binding of von Willebrand factor to human platelets
    • Fujimoto T, Hawiger J. Adenosine diphosphate induces binding of von Willebrand factor to human platelets. Nature 1982; 297: 154-6.
    • (1982) Nature , vol.297 , pp. 154-156
    • Fujimoto, T.1    Hawiger, J.2
  • 6
    • 0018758931 scopus 로고
    • Human platelets possess an inducible and saturable receptor specific for fibrinogen
    • Marguerie GA, Plow EF, Edgington TS. Human platelets possess an inducible and saturable receptor specific for fibrinogen. J Biol Chem 1979; 254: 5357-63.
    • (1979) J Biol Chem , vol.254 , pp. 5357-5363
    • Marguerie, G.A.1    Plow, E.F.2    Edgington, T.S.3
  • 7
    • 0019815603 scopus 로고
    • Specific and saturable binding of plasma fibronectin to thrombin-stimulated human platelets
    • Plow EF, Ginsberg MH. Specific and saturable binding of plasma fibronectin to thrombin-stimulated human platelets. J Biol Chem 1981; 256: 9477-82.
    • (1981) J Biol Chem , vol.256 , pp. 9477-9482
    • Plow, E.F.1    Ginsberg, M.H.2
  • 8
    • 0343418308 scopus 로고
    • Glanzmann thrombasthenia: Deficient binding of von Willebrand factor to thrombin-stimulated platelets
    • Ruggeri ZM, Bader R, De Marco L. Glanzmann thrombasthenia: Deficient binding of von Willebrand factor to thrombin-stimulated platelets. Proc Natl Acad Sci U S A 1982; 79: 6038-41.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 6038-6041
    • Ruggeri, Z.M.1    Bader, R.2    De Marco, L.3
  • 9
    • 0030870212 scopus 로고    scopus 로고
    • Networking in the hemostatic system. Integrin alphaiibbeta3 binds prothrombin and influences its activation
    • Byzova TV, Plow EF. Networking in the hemostatic system. Integrin alphaiibbeta3 binds prothrombin and influences its activation. J Biol Chem 1997; 272: 27183-8.
    • (1997) J Biol Chem , vol.272 , pp. 27183-27188
    • Byzova, T.V.1    Plow, E.F.2
  • 10
    • 0034742631 scopus 로고    scopus 로고
    • Alpha IIbbeta3 and its antagonism at the new millennium
    • Plow EF, Cierniewski CS, Xiao Z, et al. Alpha IIbbeta3 and its antagonism at the new millennium. Thromb Haemost 2001; 86: 34-40.
    • (2001) Thromb Haemost , vol.86 , pp. 34-40
    • Plow, E.F.1    Cierniewski, C.S.2    Xiao, Z.3
  • 11
    • 0034991505 scopus 로고    scopus 로고
    • Beneficial effect of glycoprotein IIb/IIIa inhibitor (AZ-1) on endothelium in Escherichia coli endotoxin-induced shock
    • Pu Q, Wiel E, Corseaux D, et al. Beneficial effect of glycoprotein IIb/IIIa inhibitor (AZ-1) on endothelium in Escherichia coli endotoxin-induced shock. Crit Care Med 2001; 29: 1181-8.
    • (2001) Crit Care Med , vol.29 , pp. 1181-1188
    • Pu, Q.1    Wiel, E.2    Corseaux, D.3
  • 12
    • 0037176934 scopus 로고    scopus 로고
    • Effect of Abciximab on prothrombin activation and thrombin generation in acute coronary syndromes without ST-segment elevation: Global Utilization of Strategies to Open Occluded Coronary Arteries Trial IV in Acute Coronary Syndromes (GUSTO IV ACS) Italian Hematologic Substudy
    • Merlini PA, Repetto A, Lombardi A, et al. Effect of Abciximab on prothrombin activation and thrombin generation in acute coronary syndromes without ST-segment elevation: Global Utilization of Strategies to Open Occluded Coronary Arteries Trial IV in Acute Coronary Syndromes (GUSTO IV ACS) Italian Hematologic Substudy. Circulation 2002; 105: 928-32.
    • (2002) Circulation , vol.105 , pp. 928-932
    • Merlini, P.A.1    Repetto, A.2    Lombardi, A.3
  • 13
    • 0034125135 scopus 로고    scopus 로고
    • In vivo demonstration of an antithrombin effect of abciximab
    • Ambrose JA, Hawkey M, Badimon JJ, et al. In vivo demonstration of an antithrombin effect of abciximab. Am J Cardiol 2000; 86: 150-2.
    • (2000) Am J Cardiol , vol.86 , pp. 150-152
    • Ambrose, J.A.1    Hawkey, M.2    Badimon, J.J.3
  • 14
    • 0035872892 scopus 로고    scopus 로고
    • Effects on thrombin generation of the platelet glycoprotein IIb/IIIa inhibitors abciximab versus tirofiban during coronary intervention
    • Ambrose JA, Doss R, Geagea JM, et al. Effects on thrombin generation of the platelet glycoprotein IIb/IIIa inhibitors abciximab versus tirofiban during coronary intervention. Am J Cardiol 2001; 87: 1231-3.
    • (2001) Am J Cardiol , vol.87 , pp. 1231-1233
    • Ambrose, J.A.1    Doss, R.2    Geagea, J.M.3
  • 15
    • 0032886556 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of glycoprotein IIb-IIIa inhibitors
    • Kleiman NS. Pharmacokinetics and pharmacodynamics of glycoprotein IIb-IIIa inhibitors. Am Heart J 1999; 138: 263-75.
    • (1999) Am Heart J , vol.138 , pp. 263-275
    • Kleiman, N.S.1
  • 16
    • 0033613544 scopus 로고    scopus 로고
    • Heparin blunts endotoxin-induced coagulation activation
    • Pernerstorfer T, Hollenstein U, Hansen J, et al. Heparin blunts endotoxin-induced coagulation activation. Circulation 1999; 100: 2485-90.
    • (1999) Circulation , vol.100 , pp. 2485-2490
    • Pernerstorfer, T.1    Hollenstein, U.2    Hansen, J.3
  • 17
    • 0034662157 scopus 로고    scopus 로고
    • The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: Relationship with activation of coagulation
    • Franco RF, De Jonge E, Dekkers PE, et al. The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: Relationship with activation of coagulation. Blood 2000; 96: 554-9.
    • (2000) Blood , vol.96 , pp. 554-559
    • Franco, R.F.1    De Jonge, E.2    Dekkers, P.E.3
  • 18
    • 0036097827 scopus 로고    scopus 로고
    • Acenocoumarol decreases tissue factor-dependent coagulation during systemic inflammation in humans
    • Hollenstein U, Homoncik M, Knobl P, et al. Acenocoumarol decreases tissue factor-dependent coagulation during systemic inflammation in humans. Clin Pharmacol Ther 2002; 71: 368-74.
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 368-374
    • Hollenstein, U.1    Homoncik, M.2    Knobl, P.3
  • 19
    • 0033013068 scopus 로고    scopus 로고
    • Dose-related inflammatory effects of intravenous endotoxin in humans: Evaluation of a new clinical lot of Escherichia coli O:113 endotoxin
    • Suffredini AF, Hochstein HD, McMahon FG. Dose-related inflammatory effects of intravenous endotoxin in humans: Evaluation of a new clinical lot of Escherichia coli O:113 endotoxin. J Infect Dis 1999; 179.
    • (1999) J Infect Dis , pp. 179
    • Suffredini, A.F.1    Hochstein, H.D.2    McMahon, F.G.3
  • 20
    • 0033034487 scopus 로고    scopus 로고
    • Regulation of adhesion molecules during human endotoxemia. No acute effects of aspirin
    • Jilma B, Blann A, Pernerstorfer T, et al. Regulation of adhesion molecules during human endotoxemia. No acute effects of aspirin. Am J Respir Crit Care Med 1999; 159: 857-63.
    • (1999) Am J Respir Crit Care Med , vol.159 , pp. 857-863
    • Jilma, B.1    Blann, A.2    Pernerstorfer, T.3
  • 21
    • 0032884985 scopus 로고    scopus 로고
    • Endotoxin-induced activation of the coagulation cascade in humans: Effect of acetylsalicylic acid and acetaminophen
    • Pernerstorfer T, Stohlawetz P, Hollenstein U, et al. Endotoxin-induced activation of the coagulation cascade in humans: Effect of acetylsalicylic acid and acetaminophen. Arterioscler Thromb Vasc Biol 1999; 19: 2517-23.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2517-2523
    • Pernerstorfer, T.1    Stohlawetz, P.2    Hollenstein, U.3
  • 22
    • 0032886666 scopus 로고    scopus 로고
    • Understanding thrombocytopenia and antigenicity with glycoprotein IIb-IIIa inhibitors
    • Madan M, Berkowitz SD. Understanding thrombocytopenia and antigenicity with glycoprotein IIb-IIIa inhibitors. Am Heart J 1999; 138: 317-26.
    • (1999) Am Heart J , vol.138 , pp. 317-326
    • Madan, M.1    Berkowitz, S.D.2
  • 23
    • 0036124016 scopus 로고    scopus 로고
    • Delayed profound thrombocytopenia presenting 7 days after use of abciximab (ReoPro)
    • Sharma S, Bhambi B, Nyitray W, et al. Delayed profound thrombocytopenia presenting 7 days after use of abciximab (ReoPro). J Cardiovasc Pharmacol Ther 2002; 7: 21-24.
    • (2002) J Cardiovasc Pharmacol Ther , vol.7 , pp. 21-24
    • Sharma, S.1    Bhambi, B.2    Nyitray, W.3
  • 24
    • 0036841416 scopus 로고    scopus 로고
    • Evaluation of coagulation markers for early diagnosis of acute coronary syndromes in the emergency room
    • Derhaschnig U, Laggner AN, Roggla M, et al. Evaluation of coagulation markers for early diagnosis of acute coronary syndromes in the emergency room. Clin Chem 2002; 48: 1924-30.
    • (2002) Clin Chem , vol.48 , pp. 1924-1930
    • Derhaschnig, U.1    Laggner, A.N.2    Roggla, M.3
  • 25
    • 0036794013 scopus 로고    scopus 로고
    • Pharmacodynamics of active site-inhibited factor VIIa in endotoxin-induced coagulation in humans
    • Jilma B, Marsik C, Mayr F, et al. Pharmacodynamics of active site-inhibited factor VIIa in endotoxin-induced coagulation in humans. Clin Pharmacol Ther 2002; 72: 403-10.
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 403-410
    • Jilma, B.1    Marsik, C.2    Mayr, F.3
  • 26
    • 18644367266 scopus 로고    scopus 로고
    • Stabilization of mRNA expression in whole blood samples
    • Rainen L, Oelmueller U, Jurgensen S, et al. Stabilization of mRNA expression in whole blood samples. Clin Chem 2002; 48: 1883-90.
    • (2002) Clin Chem , vol.48 , pp. 1883-1890
    • Rainen, L.1    Oelmueller, U.2    Jurgensen, S.3
  • 27
    • 0141567620 scopus 로고    scopus 로고
    • Recombinant human activated protein C (rhAPC, drotrecogin alfa activated) has minimal effect on markers of coagulation, fibrinolysis and inflammation in acute human endotoxemia
    • Derhaschnig U, Reiter R, Knobl P, et al. Recombinant human activated protein C (rhAPC, drotrecogin alfa activated) has minimal effect on markers of coagulation, fibrinolysis and inflammation in acute human endotoxemia. Blood 2003; 102: 2108-14.
    • (2003) Blood , vol.102 , pp. 2108-2114
    • Derhaschnig, U.1    Reiter, R.2    Knobl, P.3
  • 28
    • 0035967496 scopus 로고    scopus 로고
    • Point-of-care measured platelet inhibition correlates with a reduced risk of an adverse cardiac event after percutaneous coronary intervention: Results of the GOLD (AU-Assessing Ultegra) multicenter study
    • Steinhubl SR, Talley JD, Braden GA, et al. Point-of-care measured platelet inhibition correlates with a reduced risk of an adverse cardiac event after percutaneous coronary intervention: Results of the GOLD (AU-Assessing Ultegra) multicenter study. Circulation 2001; 103: 2572-8.
    • (2001) Circulation , vol.103 , pp. 2572-2578
    • Steinhubl, S.R.1    Talley, J.D.2    Braden, G.A.3
  • 29
    • 0022613476 scopus 로고
    • Sample size calculations for clinical pharmacology studies
    • Stolley PD, Strom BL. Sample size calculations for clinical pharmacology studies. Clin Pharmacol Ther 1986; 39: 489-90.
    • (1986) Clin Pharmacol Ther , vol.39 , pp. 489-490
    • Stolley, P.D.1    Strom, B.L.2
  • 30
    • 0034161334 scopus 로고    scopus 로고
    • Lepirudin blunts endotoxin-induced coagulation activation
    • Pernerstorfer T, Hollenstein U, Hansen JB, et al. Lepirudin blunts endotoxin-induced coagulation activation. Blood 2000; 95: 1729-34.
    • (2000) Blood , vol.95 , pp. 1729-1734
    • Pernerstorfer, T.1    Hollenstein, U.2    Hansen, J.B.3
  • 31
    • 0033559292 scopus 로고    scopus 로고
    • Vitronectin inhibits the thrombotic response to arterial injury in mice
    • Fay WP, Parker AC, Ansari MN, et al. Vitronectin inhibits the thrombotic response to arterial injury in mice. Blood 1999; 93: 1825-30.
    • (1999) Blood , vol.93 , pp. 1825-1830
    • Fay, W.P.1    Parker, A.C.2    Ansari, M.N.3
  • 32
    • 0024542044 scopus 로고
    • Vitronectin (S protein) is associated with platelets
    • Parker CJ, Stone OL, White VF, et al. Vitronectin (S protein) is associated with platelets. Br J Haematol 1989; 71: 245-52.
    • (1989) Br J Haematol , vol.71 , pp. 245-252
    • Parker, C.J.1    Stone, O.L.2    White, V.F.3
  • 33
    • 0032748716 scopus 로고    scopus 로고
    • Binding of abciximab to alpha V beta 3 and activated alpha M beta 2 receptors: With a review of platelet-leukocyte interactions
    • Coller BS. Binding of abciximab to alpha V beta 3 and activated alpha M beta 2 receptors: With a review of platelet-leukocyte interactions. Thromb Haemost 1999; 82: 326-36.
    • (1999) Thromb Haemost , vol.82 , pp. 326-336
    • Coller, B.S.1
  • 34
    • 0035871811 scopus 로고    scopus 로고
    • Antiplatelet agents in tissue factor-induced blood coagulation
    • Butenas S, Cawthern KM, Van't Veer C, et al. Antiplatelet agents in tissue factor-induced blood coagulation. Blood 2001; 97: 2314-22.
    • (2001) Blood , vol.97 , pp. 2314-2322
    • Butenas, S.1    Cawthern, K.M.2    Van't Veer, C.3
  • 35
    • 0033933316 scopus 로고    scopus 로고
    • Monoclonal antibodies against platelet membrane glycoproteins IIb/IIIa and Ibalpha inhibit platelet dependent thrombin generation by different mechanisms
    • Thomas S, Metcalfe P, Goodall AH, et al. Monoclonal antibodies against platelet membrane glycoproteins IIb/IIIa and Ibalpha inhibit platelet dependent thrombin generation by different mechanisms. Thromb Haemost 2000; 84(1): 98-103.
    • (2000) Thromb Haemost , vol.84 , Issue.1 , pp. 98-103
    • Thomas, S.1    Metcalfe, P.2    Goodall, A.H.3
  • 36
    • 0033802667 scopus 로고    scopus 로고
    • Inhibition of platelet-dependent prothrombinase activity and thrombin generation by glycoprotein IIb/IIIa receptor-directed antagonists: Potential contributing mechanism of benefit in acute coronary syndromes
    • Li Y, Spencer FA, Ball S, et al. Inhibition of platelet-dependent prothrombinase activity and thrombin generation by glycoprotein IIb/IIIa receptor-directed antagonists: Potential contributing mechanism of benefit in acute coronary syndromes. J Thromb Thrombolysis 2000; 10(1): 69-76.
    • (2000) J Thromb Thrombolysis , vol.10 , Issue.1 , pp. 69-76
    • Li, Y.1    Spencer, F.A.2    Ball, S.3
  • 37
    • 0036141796 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of AJW200, a humanized monoclonal antibody to von Willebrand factor, in monkeys
    • Kageyama S, Yamamoto H, Nakazawa H, et al. Pharmacokinetics and pharmacodynamics of AJW200, a humanized monoclonal antibody to von Willebrand factor, in monkeys. Arterioscler Thromb Vasc Biol 2002; 22: 187-92.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 187-192
    • Kageyama, S.1    Yamamoto, H.2    Nakazawa, H.3
  • 38
    • 0030941811 scopus 로고    scopus 로고
    • 7E3 F(ab′)2, a monoclonal antibody to the platelet GPIIb/IIIa receptor, protects against microangiopathic hemolytic anemia and microvascular thrombotic renal failure in baboons treated with C4b binding protein and a sublethal infusion of Escherichia coli
    • Taylor FB, Coller BS, Chang AC, et al. 7E3 F(ab′)2, a monoclonal antibody to the platelet GPIIb/IIIa receptor, protects against microangiopathic hemolytic anemia and microvascular thrombotic renal failure in baboons treated with C4b binding protein and a sublethal infusion of Escherichia coli. Blood 1997; 89: 4078-84.
    • (1997) Blood , vol.89 , pp. 4078-4084
    • Taylor, F.B.1    Coller, B.S.2    Chang, A.C.3
  • 39
    • 0032785225 scopus 로고    scopus 로고
    • Glycoprotein IIb/IIIa receptor antagonist tirofiban inhibits thrombin generation during cardiopulmonary bypass in baboons
    • Rao AK, Sun L, Hiramatsu Y, Gorman JH, III, Edmunds LH, Jr. Glycoprotein IIb/IIIa receptor antagonist tirofiban inhibits thrombin generation during cardiopulmonary bypass in baboons. Thromb Haemost 1999; 82: 140-44.
    • (1999) Thromb Haemost , vol.82 , pp. 140-144
    • Rao, A.K.1    Sun, L.2    Hiramatsu, Y.3    Gorman III, J.H.4    Edmunds Jr., L.H.5
  • 40
    • 0014004037 scopus 로고
    • Activated coagulation time of whole blood
    • Hattersley PG. Activated coagulation time of whole blood. JAMA 1966; 196: 436-40.
    • (1966) JAMA , vol.196 , pp. 436-440
    • Hattersley, P.G.1
  • 41
    • 0031845763 scopus 로고    scopus 로고
    • Administration of abciximab during percutaneous coronary intervention reduces both ex vivo platelet thrombus formation and fibrin deposition: Implications for a potential anticoagulant effect of abciximab
    • Dangas G, Badimon JJ, Coller BS, et al. Administration of abciximab during percutaneous coronary intervention reduces both ex vivo platelet thrombus formation and fibrin deposition: Implications for a potential anticoagulant effect of abciximab. Arterioscler Thromb Vasc Biol 1998; 18: 1342-9.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1342-1349
    • Dangas, G.1    Badimon, J.J.2    Coller, B.S.3
  • 42
    • 0029149015 scopus 로고
    • Endotoxin induces downregulation of tumor necrosis factor receptors on circulating monocytes and granulocytes in humans
    • Van Der Poll T, Calvano SE, Kumar A, et al. Endotoxin induces downregulation of tumor necrosis factor receptors on circulating monocytes and granulocytes in humans. Blood 1995; 86: 2754-9.
    • (1995) Blood , vol.86 , pp. 2754-2759
    • Van Der Poll, T.1    Calvano, S.E.2    Kumar, A.3
  • 43
    • 0035838353 scopus 로고    scopus 로고
    • Abciximab suppresses the rise in levels of circulating inflammatory markers after percutaneous coronary revascularization
    • Lincoff AM, Kereiakes DJ, Mascelli MA, et al. Abciximab suppresses the rise in levels of circulating inflammatory markers after percutaneous coronary revascularization. Circulation 2001; 104: 163-7.
    • (2001) Circulation , vol.104 , pp. 163-167
    • Lincoff, A.M.1    Kereiakes, D.J.2    Mascelli, M.A.3
  • 44
    • 0030794650 scopus 로고    scopus 로고
    • The origin of P-selectin as a circulating plasma protein
    • Fijnheer R, Frijns CJ, Korteweg J, et al. The origin of P-selectin as a circulating plasma protein. Thromb Haemost 1997; 77: 1081-5.
    • (1997) Thromb Haemost , vol.77 , pp. 1081-1085
    • Fijnheer, R.1    Frijns, C.J.2    Korteweg, J.3
  • 45
    • 0035139160 scopus 로고    scopus 로고
    • Effects of anticoagulation on thrombopoietin release during endotoxemia
    • Jilma-Stohlawetz P, Folman CC, Dem Borne AE, et al. Effects of anticoagulation on thrombopoietin release during endotoxemia. J Lab Clin Med 2001; 137(1): 64-9.
    • (2001) J Lab Clin Med , vol.137 , Issue.1 , pp. 64-69
    • Jilma-Stohlawetz, P.1    Folman, C.C.2    Dem Borne, A.E.3
  • 46
    • 0035949524 scopus 로고    scopus 로고
    • Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: Studies in baboons, human coronary intervention, and human acute myocardial infarction
    • Michelson AD, Barnard MR, Krueger LA, et al. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: Studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation 2001; 104: 1533-7.
    • (2001) Circulation , vol.104 , pp. 1533-1537
    • Michelson, A.D.1    Barnard, M.R.2    Krueger, L.A.3


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