Autocrine regulation of glucose metabolism in pancreatic islets

American Journal of Physiology - Endocrinology and Metabolism

Volumn 286, Issue 1 49-1, 2004, Pages

  Borelli, María I ^a   Francini, Flavio ^a   Gagliardino, Juan José ^a  

^a University of La Plata CONICET   (Argentina)

Author keywords

Autocrine regulation; Insulin secretion; Isolated islets

Indexed keywords

CALCIUM ION; CARBON 14; CARBON DIOXIDE; GLUCOSE; INSULIN; INSULIN ANTIBODY; NIFEDIPINE; TRITIUM; WATER; WORTMANNIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CARBON DIOXIDE MEASUREMENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; GLUCOSE METABOLISM; HAMSTER; HORMONAL REGULATION; HORMONE ACTION; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL;

EID: 0348048482     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00161.2003     Document Type: Article

References (45)

1. Araujo EP, Amaral ME, Souza CT, Bordin S, Ferreira F, Saad MJ, Boschero AC, Magalhaes EC, and Velloso LA. Blockade of IRS1 in isolated rat pancreatic islet improves glucose-induced insulin secretion. FEBS Lett 531: 437-442, 2002.
2. Ashcroft SJH. Glucoreceptor mechanisms and the control of insulin release and biosynthesis. Diabetologia 18: 5-15, 1980.
3. Aspinwall CA, Lakey JR, and Kennedy RT. Insulin-stimulated insulin secretion in single pancreatic beta cells. J Biol Chem 274: 6360-6365, 1999.
4. Aspinwall CA, Qian WJ, Roper MG, Kulkarni RN, Kahn CR, and Kennedy RT. Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta-cells. J Biol Chem 275: 22331-22338, 2000.
5. Coore HG and Randle PJ. Insulin secretion from rabbit pancreas in vitro. In: The Structure and Metabolism of the Pancreatic Islets, edited by Brolin SE, Hellman H, and Knutson H. New York: Pergamon, 1964, p. 295-309.
6. Da Silva Xavier G, Varadi A, Ainscow EK, and Rutter GA. Regulation of gene expression by glucose in pancreatic beta-cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3′-kinase. J Biol Chem 275: 36269-36277, 2000.
7. DeFronzo RA. Pathogenesis of type 2 diabetes: metabolic and molecular implications for identifying diabetes genes. Diabetes Rev 5: 177-269, 1997.
8. Elahi D, Nagulesparan M, Hershcopf RJ, Muller DC, Tobin JD, Blix PM, Rubenstein AH, Unger RH, and Andres R. Feedback inhibition of insulin secretion by insulin: relation to the hyperinsulinemia of obesity. N Engl J Med 306: 1196-1202, 1982.
9. Gagliardino JJ, Nierle C, and Pfeiffer EF. The effect of serotonin on in vitro insulin secretion and biosynthesis in mice. Diabetologia 10: 411-414, 1974.
10. Gazzano H, Halban P, Prentki M, Ballotti R, Brandenburg D, Fehlmann M, and Van Obberghen E. Identification of functional insulin receptors on membranes from an insulin-producing cell line (RINm5F). Biochem J 226: 867-872, 1985.
11. Harbeck MC, Louie DC, Howland J, Wolf BA, and Rothenberg PL. Expression of insulin receptor mRNA and insulin receptor substrate 1 in pancreatic islet beta-cells. Diabetes 45: 711-717, 1996.
12. Herbert V, Lau KS, Gottlieb CW, and Bleicher SJ. Coated charcoal immunoassay of insulin. J Clin Endocrinol Metab 25: 1375-1384, 1965.
13. Hügl SR, White MF, and Rhodes CJ. Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-I cells. J Biol Chem 273: 17771-17779, 1998.
14. Kahn FA, Goforth PB, Zhang M, and Satin LS. Insulin activates ATP-sensitive K+ channels in pancreatic beta-cells through a phosphatidylinositol 3-kinase-dependent pathway. Diabetes 50: 2192-2198, 2001.
15. Kitamura T, Kahn CR, and Accili D. Insulin receptor knockout mice. Annu Rev Physiol 65: 313-332, 2003.
16. Kulkarni RN, Almind K, Goren HJ, Winnay JN, Ueki K, Okada T, and Kahn CR. Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice. Diabetes 52: 1528-1534, 2003.
17. Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, and Kahn CR. Tissue-specific knockout of the insulin receptor in B cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 96: 329-339, 1999.
18. Kulkarni RN, Winnay JN, Daniels M, Brüning JC, Flier SN, Hanahan D, and Kahn CR. Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines. J Clin Invest 104: R69-R75, 1999.
19. Lacy PE and Kostianovsky M. Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16: 35-39, 1967.
20. Leibiger IB, Leibiger B, and Berggren P-O. Insulin feedback action on pancreatic beta-cell function. FEBS Lett 532: 1-6, 2002.
21. Leibiger IB, Leibiger B, Moede T, and Berggren P-O. Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways. Mol Cell 1: 933-938, 1998.
22. Leibiger B, Leibiger IB, Moede T, Kemper S, Kulkarni RN, Kahn CR, de Vargas LM, and Berggren P-O. Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells. Mol Cell 7: 559-570, 2001.
23. Leibiger B, Moede T, Uhles S, Berggren P-O, and Leibiger IB. Short-term regulation of insulin gene transcription. Biochem Soc Trans 30: 312-317, 2002.
24. Lenzen S. Glucokinase: signal recognition enzyme for glucose-induced insulin secretion. In: Nutrient Regulation of Insulin Secretion, edited by Flatt PR. London: Portland, 1992, p. 101-125.
25. Malaisse WJ and Sener A. Hexose metabolism in pancreatic islets. Feedback control of D-glucose oxidation by functional events. Biochim Biophys Acta 971: 246-254, 1988.
26. Matschinsky FM. Glucokinase as glucose sensor and metabolic signal generator in pancreatic beta-cells and hepatocytes. Diabetes 39: 647-652, 1990.
27. Paris M, Bernard-Kargar C, Berthault MF, Bowens L, and Ktorza A. Specific and combined effects of insulin and glucose on functional pancreatic beta-cell mass in vivo in adult rats. Endocrinology 144: 2717-2727, 2003.
28. Patel YC, Amherdt M, and Orci L. Quantitative electron microscopic autoradiography of insulin, glucagon, and somatostain binding sites on islets. Science 217: 1155-1156, 1982.
29. Persaud SJ, Asare-Anane H, and Jones PM. Insulin receptor activation inhibits insulin secretion from human islets of Langerhans. FEBS Lett 510: 225-228, 2002.
30. Rizzo MA, Magnuson MA, Drain PF, and Piston DW. A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin. J Biol Chem 277: 34168-34175, 2002.
31. Rizzo MA and Piston DW. Regulation of beta cell glucokinase by S-nitrosylation and association with nitric oxide synthase. J Cell Biol 161: 243-248, 2003.
32. Rhodes CJ and White MF. Molecular insights into insulin action and secretion. Eur J Clin Invest 32, Suppl 3: 3-13, 2002.
33. Sakai K, Matsumoto K, Nishikawa T, Suefuji M, Nakamaru K, Hirashima Y, Kawashima J, Shirotani T, Ichinose K, Brownlee M, and Araki E. Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic beta-cells. Biochem Biophys Res Commun 300: 216-222, 2003.
34. Schwartz MW, Woods SC, Porte DJ, Seeley RJ, and Baskin DG. Central nervous system control of food intake. Nature 404: 661-671, 2000.
35. Srivastava S and Goren J. Insulin constitutively secreted by beta-cells is necessary for glucose-stimulated insulin secretion. Diabetes 52: 2049-2056, 2003.
36. Stagner J, Samols E, Polonsky K, and Pugh W. Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas. J Clin Invest 78: 1193-1198, 1986.
37. Velloso LA, Carneiro EM, Crepaldi SC, Boschero AC, and Saad MJ. Glucose- and insulin-induced phosphorylation of the insulin receptor and its primary substrates IRS-1 and IRS-2 in rat pancreatic islets. FEBS Lett 377: 353-357, 1995.
38. Versphol EJ and Ammon HP. Evidence for presence of insulin receptors in rat islets of Langerhans. J Clin Invest 65: 1230-1237, 1980.
39. Wilson JR, Biden TJ, and Ludowyke RI. Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and RINm5F cells. Diabetes 48: 2383-2389, 1999.
40. Withers DJ, Gutierrez JS, Towery H, Burks DJ, Ren JM, Previs S, Zhang Y, Bernal D, Pons S, Shulman GI, Bonner-Weir S, and White MF. Disruption of IRS-2 causes type 2 diabetes in mice. Nature 391: 900-904, 1998.
41. 2+ homeostasis, and insulin expression and secretion. Biochemistry 39: 14912-14919, 2000.
42. 2+ homeostasis and insulin secretion. J Biol Chem 274: 18067-18074, 1999.
43. Xu G, Marshall CA, Lin T-A, Kwon G, Munivenkatappa RB, Hill JR, Lawrence JC Jr, and McDaniel ML. Insulin mediates glucose-stimulated phosphorylation of PHAS-I by pancreatic beta cells. An insulin-receptor mechanism for autoregulation of protein synthesis by translation. J Biol Chem 273: 4485-4491, 1998.
44. Yano H, Nakanishi S, Kimura K, Hanai N, Saitoh Y, Fukui Y, Nonomura Y, and Matsuda Y. Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem 268: 25846-25856, 1993.
45. Zawalich WS and Zawalich KC. Effects of glucose, exogenous insulin, and carbachol on C-peptide and insulin secretion from isolated perifused rat isletes. J Biol Chem 277: 26233-26237. 2002.