Functional reconstruction of rabbit corneal epithelium by human limbal cells cultured on amniotic membrane

Molecular Vision

Volumn 9, Issue , 2003, Pages 635-643

  Du, Yiqin ^a,b   Chen, Jing ^a   Funderburgh, James L ^b   Zhu, Xiuan ^a   Lingsong, Li ^a  

^a PEKING UNIVERSITY   (China)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; CELL NUCLEUS ANTIGEN; CONNEXIN 43; KERATIN; KERATIN 12; KERATIN 3; PARAFFIN; PLASTIC; PROTEIN P63; UNCLASSIFIED DRUG;

AMNION; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY DETECTION; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL LOSS; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CELL TRANSPLANTATION; CONTROLLED STUDY; CORNEA CELL; CORNEA EPITHELIUM; CORNEA INJURY; CORNEA LIMBUS; CORNEA NEOVASCULARIZATION; CULTURE MEDIUM; DEBRIDEMENT; EPITHELIUM CELL; FETUS CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; INTERMETHOD COMPARISON; NONHUMAN; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; TISSUE FIXATION; TISSUE REPAIR; WOUND HEALING;

AMNION; ANIMALS; BIOLOGICAL DRESSINGS; CELL DIVISION; CELL TRANSPLANTATION; CELLS, CULTURED; CONNEXIN 43; CORNEAL DISEASES; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; EPITHELIAL CELLS; EPITHELIUM, CORNEAL; FETAL TISSUE TRANSPLANTATION; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENES, TUMOR SUPPRESSOR; HUMANS; KERATINS; LIMBUS CORNEAE; PHENOTYPE; PHOSPHOPROTEINS; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STEM CELL TRANSPLANTATION; STEM CELLS; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEINS; WOUND HEALING;

EID: 0347930679     PISSN: 10900535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Schermer A, Galvin S, Sun TT. Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol 1986; 103:49-62.
2. Pellegrini G, Golisano O, Paterna P, Lambiase A, Bonini S, Rama P, De Luca M. Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface. J Cell Biol 1999; 145:769-82.
3. Tseng SC. Concept and application of limbal stem cells. Eye 1989; 3 (Pt 2):141-57.
4. Tseng SC. Regulation and clinical implications of corneal epithelial stem cells. Mol Biol Rep 1996; 23:47-58.
5. Shimazaki J, Yang HY, Tsubota K. Amniotic membrane transplantation for ocular surface reconstruction in patients with chemical and thermal burns. Ophthalmology 1997; 104:2068-76.
6. Tseng SC, Prabhasawat P, Barton K, Gray T, Meller D. Amniotic membrane transplantation with or without limbal allografts for corneal surface reconstruction in patients with limbal stem cell deficiency. Arch Ophthalmol 1998; 116:431-41.
7. Fukuda K, Chikama T, Nakamura M, Nishida T. Differential distribution of subchains of the basement membrane components type IV collagen and laminin among the amniotic membrane, cornea, and conjunctiva. Cornea 1999; 18:73-9.
8. Solomon A, Ellies P, Anderson DF, Touhami A, Grueterich M, Espana EM, Ti SE, Goto E, Feuer WJ, Tseng SC. Long-term outcome of keratolimbal allograft with or without penetrating keratoplasty for total limbal stem cell deficiency. Ophthalmology 2002; 109:1159-66.
9. Tsai RJ, Li LM, Chen JK. Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. N Engl J Med 2000; 343:86-93.
10. Pellegrini G, Traverso CE, Franzi AT, Zingirian M, Cancedda R, De Luca M. Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet 1997; 349:990-3.
11. Schwab IR, Reyes M, Isseroff RR. Successful transplantation of bioengineered tissue replacements in patients with ocular surface disease. Cornea 2000; 19:421-6.
12. Avila M, Espana M, Moreno C, Pena C. Reconstruction of ocular surface with heterologous limbal epithelium and amniotic membrane in a rabbit model. Cornea 2001; 20:414-20.
13. Meller D, Pires RT, Tseng SC. Ex vivo preservation and expansion of human limbal epithelial stem cells on amniotic membrane cultures. Br J Ophthalmol 2002; 86:463-71.
14. Shimazaki J, Aiba M, Goto E, Kato N, Shimmura S, Tsubota K. Transplantation of human limbal epithelium cultivated on amniotic membrane for the treatment of severe ocular surface disorders. Ophthalmology 2002; 109:1285-90.
15. Grueterich M, Espana E, Tseng SC. Connexin 43 expression and proliferation of human limbal epithelium on intact and denuded amniotic membrane. Invest Ophthalmol Vis Sci 2002; 43:63-71.
16. Wolosin JM, Xiong X, Schutte M, Stegman Z, Tieng A. Stem cells and differentiation stages in the limbo-corneal epithelium. Prog Retin Eye Res 2000; 19:223-55.
17. Wu RL, Zhu G, Galvin S, Xu C, Haseba T, Chaloin-Dufau C, Dhouailly D, Wei ZG, Lavker RM, Kao WY, et al. Lineage-specific and differentiation-dependent expression of K12 keratin in rabbit corneal/limbal epithelial cells: cDNA cloning and northern blot analysis. Differentiation 1994; 55:137-44.
18. Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, Bronson RT, Tabin C, Sharpe A, Caput D, Crum C, McKeon F. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 1999; 398:714-8.
19. Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V, Andrews NC, Caput D, McKeon F. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 1998; 2:305-16.
20. Pellegrini G, Dellambra E, Golisano O, Martinelli E, Fantozzi I, Bondanza S, Ponzin D, McKeon F, De Luca M. p63 identifies keratinocyte stem cells. Proc Natl Acad Sci U S A 2001; 98:3156-61.
21. Tseng SC. Amniotic membrane transplantation for ocular surface reconstruction. Biosci Rep 2001; 21:481-9.
22. Grueterich M, Espana EM, Tseng SC. Modulation of keratin and connexin expression in limbal epithelium expanded on denuded amniotic membrane with and without a 3T3 fibroblast feeder layer. Invest Ophthalmol Vis Sci 2003; 44:4230-6.
23. Kenyon KR, Tseng SC. Limbal autograft transplantation for ocular surface disorders. Ophthalmology 1989; 96:709-22; discussion722-3.
24. Brown GW, Hayden GF. Nonparametric methods. Clinical applications. Clin Pediatr (Phila) 1985; 24:490-8.
25. Matic M, Petrov IN, Chen S, Wang C, Dimitrijevich SD, Wolosin JM. Stem cells of the corneal epithelium lack connexins and metabolite transfer capacity. Differentiation 1997; 61:251-60.
26. Grueterich M, Tseng SC. Human limbal progenitor cells expanded on intact amniotic membrane ex vivo. Arch Ophthalmol 2002; 120:783-90.
27. Hernandez Galindo EE, Theiss C, Steuhl KP, Meller D. Gap junctional communication in microinjected human limbal and peripheral corneal epithelial cells cultured on intact amniotic membrane. Exp Eye Res 2003; 76:303-14.
28. Koizumi N, Fullwood NJ, Bairaktaris G, Inatomi T, Kinoshita S, Quantock AJ. Cultivation of corneal epithelial cells on intact and denuded human amniotic membrane. Invest Ophthalmol Vis Sci 2000; 41:2506-13.
29. Meller D, Dabul V, Tseng SC. Expansion of conjunctival epithelial progenitor cells on amniotic membrane. Exp Eye Res 2002; 74:537-45.
30. Tseng SC, Meller D, Anderson DF, Touhami A, Pires RT, Gruterich M, Solomon A, Espana E, Sandoval H, Ti SE, Goto E. Ex vivo preservation and expansion of human limbal epithelial stem cells on amniotic membrane for treating corneal diseases with total limbal stem cell deficiency. Adv Exp Med Biol 2002; 506:1323-34.
31. Grueterich M, Espana EM, Touhami A, Ti SE, Tseng SC. Phenotypic study of a case with successful transplantation of ex vivo expanded human limbal epithelium for unilateral total limbal stem cell deficiency. Ophthalmology 2002; 109:1547-52.
32. Koizumi N, Inatomi T, Quantock AJ, Fullwood NJ, Dota A, Kinoshita S. Amniotic membrane as a substrate for cultivating limbal corneal epithelial cells for autologous transplantation in rabbits. Cornea 2000; 19:65-71.
33. Ti SE, Anderson D, Touhami A, Kim C, Tseng SC. Factors affecting outcome following transplantation of ex vivo expanded limbal epithelium on amniotic membrane for total limbal deficiency in rabbits. Invest Ophthalmol Vis Sci 2002; 43:2584-92.
34. Li DQ, Tseng SC. Three patterns of cytokine expression potentially involved in epithelial-fibroblast interactions of human ocular surface. J Cell Physiol 1995; 163:61-79.