Oral Cancer Induced by Cigarette Smoke - The Mediatory Role of the Salivary Antioxidant System

Anticancer Research

Volumn 23, Issue 6 D, 2003, Pages 5125-5128

  Nagler, Rafael M ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Antioxidants; Cigarette smoke; Oral cancer; Saliva; SCC; Tobacco

Indexed keywords

ANTIOXIDANT; CIGARETTE SMOKE; EPIDERMAL GROWTH FACTOR; MYELOPEROXIDASE; PEROXIDASE; SALIVARY PEROXIDASE; SECRETORY IMMUNOGLOBULIN; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIOXIDANT ACTIVITY; CANCER PREVENTION; CIGARETTE SMOKING; ENZYME ACTIVITY; HOST RESISTANCE; MOUTH CANCER; MOUTH CAVITY; NONHUMAN; PAROTID GLAND; PRIORITY JOURNAL; REVIEW; SALIVA; SALIVARY GLAND; SQUAMOUS CELL CARCINOMA; TOBACCO;

ANTIOXIDANTS; HUMANS; MOUTH NEOPLASMS; PEROXIDASES; SALIVA; SMOKING;

EID: 0347793929     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (54)

1. Nagler RM, Lischinsky S, Diamond E, Klein I and Reznick A: New insights into salivary lactate dehydrogenase of human subjects. J Lab Clin Med 137: 363-369, 2001.
2. Nagler RM, Marmary Y, Golan E and Chevion M: Novel protection strategy against irradiation-induced and transition metal-mediated damage to salivary glands. Radiat Re 142: 271-276, 1998.
3. Nagler RM, Marmary Y, Krausz Y et al: Salivary gland dysfunction in human acute and chronic graft versus host disease (GVHD). Bone Marrow Trans 17: 219-224, 1996.
4. Reznick AZ, Han D and Packer L: Cigarette smoke induced oxidation of human plasma proteins, lipids and antioxidants, selective protection by the biothiols dihydrolipoic acid and glutathion. Redox Report 3: 169-174, 1997.
5. Scheff'e H: The Analysis of Variance. New York, John Wiley & Sons, 1959.
6. Hockberg Y and Tamhane AC: Multiple Comparison Procedures. New York, John Wiley & Sons, 1987.
7. Gosset WS: On the probable error of a mean. Biometrika 6: 1-25, 1908.
8. Carlsson J: Salivary peroxidase: an important part of our defense against oxygen toxicity. J Oral Pathol 16: 412-416, 1987.
9. Grisham MB and Ryan EM: Cytotoxic properties of salivary oxidants. Am J Physiol 258: C115-C121, 1990.
10. Darby-Weydert CJ, Smith BB, Xu L, Kergel KC, Ritchie JM, Davis CS et al: Inhibition of oral cancer cell growth by adenovirus MnSOD plus BCNU treatment. Free Radic Biol Med 1, 34(3): 316-29, 2003.
11. Chen CL, Chi CW and Liu TY: Hydroxyl radical formation and oxidative DNA damage induced by areca quid in vivo. J Toxicol Environ Health A 65(304): 327-36, 2002.
12. Dayan D, Hirshberg A, Kaplan I, Rotem N and Bodner L: Experimental tongue cancer in desalivated rats. Oral Oncol 33: 105-109, 1981.
13. Nishioka H, Nishi K and Kyokane K: Human saliva inactivates mutagenicity of carcinogens. Mutat Res 85: 323-333, 1981.
14. Knak R, Rutsats K and Göcke R: Salivary investigations in oral lichen planus (abstract). J Dent Res 77: 979, 1998.
15. Nair UJ, Floyd RA, Nair J, Bussachini V, Friesen M and Bartsch H: Formation of reactive oxygen species and of 8-hydroxydeoxyguanosine in DNA in vitro with betel quid ingredients. Chem Biol Interact 63: 157-169, 1987.
16. Zappacosta B, Persichilli S, Mordente A, Minucci A, Lazzaro D, Meucci E and Giardina B: Inhibition of salivary enzymes by cigarette smoke and the protective role of glutathione. Hum Exp Toxicol 21: 7-11, 2002.
17. Rao RK, Thomas DW, Pepperl S et al: Salivary epidermal growth factor plays a role in protection of ileal mucosal integrity. Dig Dis Sci 42: 2175-2181, 1997.
18. Marcozzi G: A rapid procedure for the purification of human salivary peroxidase. Biomed Chromatogr 10: 97-98, 1996.
19. Kohen R, Tirosh O and Kopolovich K: The reductive capacity index of saliva obtained from donors of various ages. Exp Gerontol 27: 161-168, 1992.
20. Meucci E, Littarru C, Deli G et al: Antioxidant status and dialysis: plasma and saliva antioxidant activity in patients with fluctuating urate levels. Free Rad Res 29: 367-376, 1998.
21. Moore S, Calder KAC, Miller NJ and Rice-Evans C: Antioxidant activity of saliva and periodontal disease. Free Rad Res 21: 417-425, 1994.
22. Hirayama O, Takagi M, Hukumoto K and Katoh S: Evaluation of antioxidant activity by chemiluminescence. Anal Biochem 247: 237-241, 1997.
23. Kondakova I, Lissi EA and Pizarro M: Total reactive antioxidant potential in human saliva of smokers and non-smokers. Biochem Mol Biol Int 6: 911-920, 1999.
24. Terao J and Nagao A: Antioxidative effect of human saliva on lipid peroxidation. Agric Biol Chem 55: 869-872, 1991.
25. Tan SG and Teng YS: Saliva acid phosphatases and amylase in senoi and aboriginal malays and superoxide dismutase in various racial groups of peninsular malaysia. Jinrui Idengaku Zasshi 23: 133-138, 1978.
26. Pereslegina IA, Zhukova EA, Belentsova LA et al: Antioxidant components of erythrocytes and digestive secretions in childhood gastroduodenal diseases. Vopr Med Khim 39: 45-48, 1993.
27. Pereslegina IA: The activity of antioxidant enzymes in the saliva of normal children. Lab Delo 11: 20-23, 1989.
28. Pereslegina IA: Superoxide dismutase activity of digestive secretions. Ukrainskii Biohimicheskii Zhurnal 62: 53-58, 1990.
29. Matsunaga S, Furuta S, Nishimoto K et al: The activity of superoxide dismutase in patients with taste and smell dysfunction. Nippon Jibiinkoka Gakki Kaiho 97: 1664-1668, 1994.
30. Mansson-Rahemtulla B, Rahemtulla F, Baldone DC et al: Purification and characterization of human salivary peroxidase. Biochemistry 27: 233-239, 1988.
31. Mansson-Rahemtulla B, Rahemtulla F and Humphreys-Beher MG: Human salivary peroxidase and bovine lactoperoxidase are cross-reactive. J Dent Res 69: 1839-1846, 1990.
32. Pruitt KM, Kamau DN, Miller K et al: Quantitative, standardized assays for determining the concentrations of bovine lactoperoxidase, human salivary peroxidase, and human myeloperoxidase. Anal Biochem 191: 278-286, 1990.
33. Morrison M, Allen PZ, Bright J and Jayasinghe W: Identification and isolation of lactoperoxidase from saligland. Arch Biochem Biophys 111: 126-133, 1965.
34. Revis GJ: Immunoelectrophoretic identification of peroxidase in human parotid saliva. Arch Oral Biol 22: 155-158, 1997.
35. Kowolik MJ and Grant M: Myeloperoxidase activity in human gingival crevicular neutrophils. Arch Oral Biol 28: 293-295, 1983.
36. Smith QT and Yang CH: Salivary myeloperoxidase of young adults. Proc Soc Exp Biol Med 175: 468-475, 1984.
37. Azen EA: Genetics of salivary protein polymorphisms. Crit Rev Oral Biol Med 4: 479-485, 1993.
38. Lenander-Lumikari M, Puhakka T, Makela MJ et al: Effects of the common cold and intranasal fluticasone propionate treatment on mucosal host defense assessed by human saliva. Endodontics 87: 695-699, 1999.
39. Mandel ID, Behrman J, Levy R and Weinstein D: The salivary lactoperoxidase system in caries-resistant and -susceptible adults. J Dent Res 62: 922-925, 1983.
40. Toljanic JA, Siddiqui AA, Patterson GL and Irwin ME: An evaluation of a dentrifice containing salivary peroxidase elements for the control of gingival disease in patients with irradiated head and neck cancer. J Prosthet Dent 76: 292-296, 1996.
41. Dogon IL, Kerr AC and Amdur BH: Characterization of an antibacterial factor in human parotid secretions active against lactobacillus casei. Arch Oral Biol 7: 81-90, 1962.
42. Jalil RA: Concentrations of thiocyanate and hypothiocyanite in the saliva of young adults. J Nihon Univ Sch Dent 36: 254-260, 1994.
43. Guven Y, Satman I, Dinccag N and Alptekin S: Salivary peroxidase activity in whole saliva of patients with insulin-dependent (type-1) diabetes mellitus. J Clin Periodontol 23: 879-881, 1996.
44. Thomas EL and Aune TM: Lactoperoxidase, peroxide, thiocyanate antimicrobial system: correlation of sulfhydryl oxidation with antimicrobial action. Infect Immun 20: 456-463, 1978.
45. Aune TM and Thomas EL: Accumulation of hypothiocyanite ion during peroxidase-catalyzed oxidation of thiocyanate ion. Eur J Biochem 80: 209-214, 1997.
46. Hoogendoorn H, Piessens JP, Scholtes W and Stoddard LA: Hypothiocyanate ion, the inhibitor formed by the system lactoperoxidase-thiocyanate-hydrogen peroxide, i: identification of the inhibiting compound. Caries Res 11: 77-84, 1997.
47. Thomas EL, Milligan TW, Joyner RE and Jefferson MM: Antibacterial activity of hydrogen peroxide and the lactoperoxidase-hydrogen peroxide-thiocyanate system against oral streptococci. Infect Immun 62: 529-535, 1994.
48. Kou F and Takahama U: Hydrogen peroxide-induced luminescence and evolution of molecular oxygen in human saliva. Arch Oral Biol 40: 15-21,1995.
49. Nagler RM, Klein I, Zarzhevsky N, Drigues N and Reznick AZ: Characterization of the differentiated antioxidant profile of human saliva. Free Radic Biol Med 32(3): 268-277, 2002.
50. Nagler RM, Marmary Y, Fox PC, Baum B, Har-El R and Chevion M: Irradiation-induced damage to the salivary glands: the role of redox-active iron and copper. Radiation Res 147: 468-475, 1997.
51. Nishioka T, Kimura M and Takahama U: Effects of pH and thiocyanate on hydrogen peroxide-induced evolution of molecular oxygen in human mixed saliva. Arch Oral Biol 41: 911-917, 1996.
52. Nagler R, Lischinsky S, Diamond E, Drigues N, Klein Y and Reznick AZ: Effect of cigarette smoke on salivary proteins and enzyme activities. Arch Biochem Biophys 379: 229-236, 2000.
53. Zappacosta B, Persichilli S, De Sole P, Mordente A and Giardina B: Effect of smoking one cigarette on antioxidant metabolites in the saliva of healthy smokers. Arch Oral Bio 44: 485-488, 1999.
54. Reznick AZ, Klein I, Eiserich JP, Cross CE and Nagler RM: Inhibition of oral peroxidase activity by cigarette smoke: in vivo and in vitro studies. Free Radical Biology & Medicine 34: 377-384, 2003.