Novel protection strategy against X-ray-induced damage to salivary glands

Radiation Research

Volumn 149, Issue 3, 1998, Pages 271-276

  Nagler, R ^a   Marmary, Y ^b   Golan, E ^b   Chevion, M ^b  

^a RAMBAM MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

DEFEROXAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; MALE; NONHUMAN; PAROTID GLAND; PRIORITY JOURNAL; RADIATION INJURY; RADIATION PROTECTION; RADIOSENSITIVITY; RAT; SALIVARY GLAND DISEASE; SALIVATION; SUBMANDIBULAR GLAND; X IRRADIATION;

ANIMALS; BODY WEIGHT; DEFEROXAMINE; MALE; ORGAN SIZE; ORGANOMETALLIC COMPOUNDS; RADIATION-PROTECTIVE AGENTS; RATS; RATS, WISTAR; SALIVARY GLANDS; SALIVARY PROTEINS; SALIVATION; TIME FACTORS; X-RAYS;

ANIMALIA;

EID: 0031914611     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579960     Document Type: Article

References (41)

1. I. H. Valdez, Radiation induced salivary dysfunction: Clinical course and significance. Special Care Dent. 11, 252-255 (1991).
2. A. Kuten, H. Ben-Aryeh, I. Berdichevsky, L. Ore, R. Szargel, D. Gutman and E. Robinson, Oral side effects of head and neck irradiation: Correlation between clinical manifestations and laboratory data. Int. J. Radiat. Oncol. Biol. Phys. 12, 401-405 (1986).
3. H. K. Kashima, W. R. Kirkham and J. R. Andrews, Post-irradiation sialodentis: A study of the clinical features, histopathologic changes and serum enzyme variations following irradiation of human salivary glands. Am. J. Roentgenol. Radium Ther. Nucl. Med. 94, 271-291 (1965).
4. R. M Nagler, B. J. Baum and P. C. Fox, Effects of X irradiation on the function of rat salivary glands at 3 and 40 days. Radiat. Res. 136, 392-396 (1993).
5. R. M. Nagler, B. J. Baum and P. C. Fox, Acute effects of X irradiation on the function of rat salivary glands. Radiat. Res. 136, 42-47 (1993).
6. I. L. Shannon, E. N. Starcke and W. B. Wescott, Effect of radiotherapy on whole saliva flow. J. Dent. Res. 56, 693 (1977).
7. I. L. Shannon, J. N. Trodahl and E. N. Starcke, Radiosensitivity of the human parotid gland. Proc. Soc. Exp. Biol. Med. 157, 50-53 (1978).
8. R. M. Nagler, B. J. Baum and P. C. Fox, Long term effects of x-irradiation on rat salivary gland. J. Dent. Res. 73, 213 (1994). [Abstract]
9. S. K. El-Mofty and A. J. Kahn, Early membrane injury in lethally-irradiated salivary gland cells. Int. J. Radiat. Biol. 39, 55-62 (1981).
10. L. C. Stephens, G. K. King, L. J. Peters, K. K. Ang, T. E. Schultheiss and J. H. Jardine, Unique radiosensitivity of serous cells in rhesus monkey submandibular glands. Am. J. Pathol. 124, 479-487 (1986).
11. L. C. Stephens, T. E. Schultheiss, S. M. Small, K. K. Ang and L. J. Peters, Response of parotid gland organ culture to radiation. Radiat. Res. 120, 140-153 (1989).
12. L. C. Stephens, T. E. Schultheiss, R. E. Price, K. K. Ang and L. J. Peters, Radiation apoptosis of serous cells of salivary and lacrimal glands. Cancer 61, 1539-1543 (1991).
13. L. C. Stephens, K. K. Ang, T. E. Schultheiss, G. K. King, W. A. Brock and L. J. Peters, Target cell and mode of radiation injury in rhesus salivary glands. Radiother. Oncol. 7, 253-258 (1986).
14. K. Abok, U. Brunk, B. Jung and J. Ericsson, Morphologic and histochemical studies on the differing radiosensitivity of ductular and acinar cells of the rat submandibular gland. Virchows Arch. B Cell Pathol. 45, 443-460 (1984).
15. L. M. Sreebny, The Salivary System, pp. 21-41. CRC Press, Boca Raton, FL, 1988.
16. N. E. Pratt and M. Sodicoff, Ultrastructural injury following x-irradiation of rat parotid gland acinar cells. Arch. Oral Biol. 17, 1177-1186 (1972).
17. M. M. Sholley, M. Sodicoff and N. E. Pratt, Early radiation injury in the rat parotid gland. Lab. Invest. 31, 340-354 (1974).
18. M. Chevion, A site specific mechanism for free radical induced biological damage: The essential role of redox-active transition metals. Free Radical Biol Med. 5, 27-37 (1988).
19. P. C. Read and N. E. Steidler, X-irradiation induced degranulation of cells of convoluted granular tubules of murine submandibular salivary glands. J. Biol. Buccale 13, 307-313 (1985).
20. A. Vissink, E. J. 's-Gravenmade, E. E. Ligeon and A. W. T. Konings, Effects of split-dose X irradiation on rat salivary gland function. Radiat. Res. 127, 52-57 (1991).
21. I. Furuno, T. Iwasaki and H. Matsudaira, Effects of X irradiation on cell proliferation and DNA synthesis induced by administration of isoproterenol in salivary glands of the mouse. Radiat. Res. 57, 434-441 (1974).
22. H. A. S. van den Brenk, Response of sialodenotrophism to x-radio-sensitivity and recovery of differentiated salivary acinar cells. Int. J. Radiat. Biol 14, 281-286 (1968).
23. P. Gemryd, L. E. Norberg and P. G. Lundquist, Studies on the regranulation of salivary gland serous cells: An electron microscopal study in the rat. ORL 54, 33-37 (1992).
24. P. G. Lundquist and L. E. Norberg, Salivary gland morphology after β-adrenergic acholinergic stimulation. Acta Otolaryngol. 447, 14-22 (1988).
25. L. E. Norberg and B. Forsberg, Alpha-adrenergic stimulation and radiosensitivity of the rat submaxillary gland. Arch. Otorhinolaryngol. 49, 302-313 (1987).
26. C. A. Schneyer, M. G. Humphreys-Beher and H. D. Hall, Comparison of cyclocytidine and sympathetic nerve induced changes in norepinephrine and adrenoceptors in salivary gland. J. Auton. Nerv. Syst. 35, 93-98 (1991).
27. M. Chevion, Protection against free radical induced transition metal-mediated damage: The use of "pull" and "push" mechanisms. Free Radical Res. Commun. 12/13, 691-696 (1991).
28. R. N. Nagler, Y. Marmary, P. C. Fox, B. J. Baum, R. Har-El and M. Chevion, Irradiation-induced damage to the salivary glands: The role of redox-active iron and copper. Radiat Res. 147, 468-475 (1997).
29. H. Keberle, The biochemistry of desferrioxamine and its relation to iron metabolism. Ann. NY Acad. Sci. 119, 758-768 (1964).
30. A. Ophir, E. Berenshtein, N. Kitrossky and E. Averbukh, Protection of the transiently ischemic cat retina by zinc-desferrioxamine. Invest. Ophthalmol. Vis. Sci. 35, 1212-1222 (1994).
31. M. Chevion, L. Chuang and J. Golenser, Effects of zinc-desferrioxamine on Plasmodium falciparum in culture. Antimicrob. Agents Chemother. 39, 1902-1905 (1995).
32. P. C. Fox, P. F. van der Yen, D. C. Sonies, J. M. Weiffenbach and B. J. Baum, Xerostomia: Evaluation of a symptom with increasing significance. J. Am. Dent. Assoc. 110, 519-525 (1985).
33. P. Arenberg, Quantitative determinations of protein in saliva: A comparison of analytical methods. Scand. J. Dent. Res. 79, 60-64 (1971).
34. R. M. Nagler, B. J. Baum and P. C. Fox, A 2 week pair-fed study of early x-irradiation effects on rat salivary gland function. Arch. Oral. Biol. 41, 713 (1996).
35. Y. Hiramatsu, R. M. Nagler, P. C. Fox and B. J. Baum. Rat salivary gland blood flow and blood-to-tissue partition co-efficients following x-irradiation. Arch. Oral Biol 39, 77-80 (1994).
36. H. D. Mosier, Jr. and R. A. Jansons, Stunted growth in rats following x-irradiation of the head. Growth 31, 139-148 (1967).
37. J. Maisin, P. Maldague, A. Dunjic and H. Maisin, Syndromes mortels et effets tardifs des irradiations totales et subtotales chez le rat. J. Belg. Radiol. 40, 346-398 (1957).
38. L. M. Sreeberg, Recognition and treatment of salivary induced conditions. Int. Dent. J. 39, 197-204 (1989).
39. R. Nagler and A. Nagler, Effects of ionizing irradiation and β-adrenergic stimulation on gene expression in rat submandibular glands Anticancer Res. 16, 2749-2756 (1996).
40. P. M. Mertz, P. C. Fox, A. Pluta, B. J. Baum and E. E. Kousvelari, Effects of ionizing radiation and β-adrenergic stimulation on the expression of early response genes in rat parotid glands. Radiat. Res. 130, 104-112 (1992).
41. L. E. Norberg and P. G. Lundquist, Aspects of salivary gland radiosensitivity, effects of sialogogues and irradiation. Arch. Otorhinolaryngol. 246, 200-204 (1989).