Spinal root avulsion-induced upregulation of osteopontin expression in the adult rat spinal cord

Acta Neuropathologica

Volumn 107, Issue 1, 2004, Pages 8-16

  Fu, Yonghui ^a,b   Hashimoto, Masayuki ^b   Ino, Hidetoshi ^b   Murakami, Masazumi ^b   Yamazaki, Masashi ^b   Moriya, Hideshige ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

Astrocyte; Microglia; Osteopontin; Spina root avulsion; Spinal cord

Indexed keywords

MESSENGER RNA; OSTEOPONTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; AVULSION INJURY; CELL COUNT; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATION; MACROPHAGE; MALE; MICROGLIA; NEUROPROTECTION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA ANALYSIS; SPINAL CORD INJURY; SPINAL CORD MOTONEURON; UPREGULATION;

ANIMALS; ASTROCYTES; BLOTTING, NORTHERN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MACROPHAGES; MALE; MICROGLIA; MOTOR NEURONS; OSTEOPONTIN; RATS; RATS, WISTAR; RNA, MESSENGER; SIALOGLYCOPROTEINS; SPINAL CORD; SPINAL CORD INJURIES; SPINAL NERVE ROOTS; UP-REGULATION;

EID: 0347724245     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-003-0775-1     Document Type: Article

References (31)

1. Brown LF, Papadopoulos-Sergiou A, Berse B, Manseau EJ, Tognazzi K, Perruzzi CA, Dvorak HF, Senger DR (1994) Osteopontin expression and distribution in human carcinomas. Am J Pathol 145:610-623
2. Carlson SL, Parish ME, Springer JE, Doty K, Dossett L (1998) Acute inflammatory response in spinal cord following impact injury. Exp Neurol 151:77-88
3. Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L (2001) The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science 294:1731-1735
4. Clark RK, Lee EV, Fish CJ, White RF, Price WJ, Jonak ZL, Feuerstein GZ, Barone FC (1993) Development of tissue damage, inflammation and resolution following stroke: an immunohistochemical and quantitative planimetric study. Brain Res Bull 31:565-572
5. Clark RK, Lee EV, White RF, Jonak ZL, Feuerstein GZ, Barone FC (1994) Reperfusion following focal stroke hastens inflammation and resolution of ischemic injured tissue. Brain Res Bull 35:387-392
6. Cullheim S, Carlstedt T, Risling M (1999) Axon regeneration of spinal motoneurons following a lesion at the cord-ventral root interface. Spinal Cord 37:811-819
7. Denhardt DT, Guo X (1993) Osteopontin: a protein with diverse functions. FASEB J 7:1475-1482
8. D'Errico JA, Sauk JJ, Prince CW, Somerman MJ (1995) Osteopontin adhesion receptors on gingival fibroblasts. J Periodontal Res 30:34-41
9. Ellison JA, Velier JJ, Spera P, Jonak ZL, Wang X, Barone FC, Feuerstein MD (1998) Osteopontin and its integrin receptor αvβ3 are upregulated during formation of the glial scar after focal stroke. Stroke 29:1698-1707
10. Hashimoto M, Koda M, Ino H, Murakami M, Yamazaki M, Hideshige M (2003) Upregulation of osteopontin expression in rat spinal cord microglia after traumatic injury. J Neurotrauma 20:287-296
11. He JW, Hirata K, Kuraoka A, Kawabuchi M (2000) An improved method for avulsion of lumber nerve roots as an experimental model of nitric oxide- mediated neuronal degeneration. Brain Res Brain Res Protoc 5:223-230
12. Hwang SM, Lopez CA, Heck DE, Gardner CR, Laskin DL, Laskin JD, Denhardt DT (1994) Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells. J Biol Chem 269:711-715
13. Ikeda O, Murakami M, Ino H, Yamazaki M, Nemoto T, Koda M, Nakayama C, Moriya H (2001) Acute up-regulation of brain-derived neurotrophic factor expression resulting from experimentally induced injury in the rat spinal cord. Acta Neuropathol 102:239-245
14. Ikeda O, Murakami M, Ino H, Yamazaki M, Koda M, Nakayama C, Moriya H (2002) Effects of brain-derived neurotrophic factor (BDNF) on compression-induced spinal cord injury: BDNF atenuates down-regulation of superoxide dismutase expression and promotes up-regulation of myelin basic protein expression. J Neuropathol Exp Neurol 61:142-153
15. Kishino A, Ishige Y, Tatsuno T, Nakayama C, Noguchi H (1997) BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth. Exp Neurol 144:273-286
16. Koliatsos VE, Price WL, Pardo CA, Price DL (1994) Ventral root avulsion: an experimental model of death of adult motor neurons. J Comp Neurol 342:35-44
17. Lee M-Y, Shin S-L, Choi Y-S, Kim E-J, Cha J-H, Chun M-H, Lee SB, Kim SY (1999) Transient upregulation of osteopontin mRNA in hippocampus and striatum following global forebrain ischemia in rats. Neurosci Lett 271:81-84
18. Lindholm T, Cullheim S, Deckner M, Carlstedt T, Risling M (2002) Expression of neuregulin and ErbB3 and ErbB4 after a traumatic lesion in the ventral funiculus of the spinal cord and in the intact primary olfactory system. Exp Brain Res 142:81-90
19. Martin LJ, Kaiser A, Price AC (1999) Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis. J Neurobiol 40:185-201
20. Novikov L, Novikova L, Kellerth JO (1995) Brain-derived neurotrophic factor promotes survival and blocks nitric oxide synthase expression in adult rat spinal motoneurons after ventral root avulsion. Neurosci Lett 200:45-48
21. Olsson T, Lundberg C, Lidman O, Piehl F (2000) Genetic regulation of nerve avulsion-induced spinal cord inflammation. Ann NY Acad Sci 917:186-196
22. Satake K, Matsuyama Y, Kamiya M, Kawakami H, Iwata H, Adachi K, et al (2000) Nitric oxide via macrophage iNOS induces apoptosis following traumatic spinal cord injury. Brain Res Mol Brain Res 85:114-122
23. Schnell L, Fearn S, Klassen H, Schwab E, Perry H (1999) Acute inflammatory responses to mechanical lesions in the CNS: differences between brain and spinal cord. Eur J Neurosci 11:3684-3688
24. Singh RP, Patarca R, Schwartz J, Singh P, Cantor H (1990) Definition of a specific interaction between the early T lymphocyte activation 1 (Eta-1) protein and murine macrophages in vitro and its effect upon macrophages in vivo. J Exp Med 171: 1931-1942
25. Terai K, Takano-Yamamoto T, Ohba Y, Hiura K (1999) Role of osteopontin in bone remodeling caused by mechanical stress. J Bone Miner Res 14:839-849
26. Vandesande F, Dierickx K (1975) Identification of the vasopressin producing and of the oxytocin producing neurons in the hypothalmic magnocellular neurosecretory system of the rat. Cell Tissue Res 164:153-162
27. Vandesande F, Dierickx K (1976) Immunocytochemical demonstration of separate vasotocinergic and mesotocinergic neurons in the amphibian hypothalamic magnocellular neurosecretory system. Cell Tissue Res 175:289-296
28. Wang X, Louden C, Yue TL, Ellison JA, Barone FC, Solleveld HA, Feuerstein GZ (1998) Delayed expression of osteopontin after focal stroke in the rat. J Neurosci 18:2075-2083
29. Wu W, Li L (1993) Inhibition of nitric oxide synthase reduces motoneuron death due to spinal root avulsion. Neurosci Lett 153:121-124
30. Yamazaki M, Nakajima F, Ogasawara A, Moriya H, Majeska RJ, Einhorn TA (1999) Spatial and temporal distribution of CD44 and osteopontin in fracture callus. J Bone Joint Surg 81B:508-515
31. Yue TL, Mckenna PJ, Ohlstein EH, Farach-Carson MC, Butler WT, Johanson K, McDevitt P, Feuerstein GZ, Stadel JM (1994) Osteopontin-stimulated vascular smooth muscle cell migration is mediated by β3 integrin. Exp Cell Res 214:459-464