In Vitro and in Vivo Regulation of Antioxidant Response Element-Dependent Gene Expression by Estrogens

Endocrinology

Volumn 145, Issue 1, 2004, Pages 311-317

  Ansell, P J ^a,b   Espinosa Nicholas, C ^a,b   Curran, E M ^b   Judy, B M ^b   Philips, B J ^a,b,c   Hannink, M ^a   Lubahn, D B ^a,b  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c Roswell Cancer Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; CELL DNA; CIS ACTING ELEMENT; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; GLUTATHIONE TRANSFERASE; PHYTOESTROGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CANCER RISK; CARCINOGENESIS; CELL TYPE; CONTROLLED STUDY; DNA DAMAGE; DNA RESPONSIVE ELEMENT; DNA SEQUENCE; DOSE RESPONSE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME MECHANISM; ESTROGEN ACTIVITY; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HORMONAL REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL;

ANIMALS; ANTIOXIDANTS; BASE SEQUENCE; BREAST NEOPLASMS; CELL LINE, TUMOR; COS CELLS; ENZYME ACTIVATION; ESTROGENS; FEMALE; GENE EXPRESSION; GLUTATHIONE TRANSFERASE; HUMANS; ISOFLAVONES; MICE; MICE, INBRED C57BL; NAD(P)H DEHYDROGENASE (QUINONE); PHYTOESTROGENS; PLANT PREPARATIONS; RECEPTORS, ESTROGEN; RESPONSE ELEMENTS; TRANSFECTION;

EID: 0347719510     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0817     Document Type: Article

References (39)

1. Guengerich FP, Shimada T 1991 Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes. Chem Res Toxicol 4:391-407
2. Cholerton S, Daly AK, Idle JR 1992 The role of individual human cytochromes P450 in drug metabolism and clinical response. Trends Pharmacol Sci 13:434-439
3. Korzekwa KR, Jones JP 1993 Predicting the cytochrome P450 mediated metabolism of xenobiotics. Pharmacogenetics 3:1-18
4. Miller JA, Surh YJ 1994 Historical perspectives on conjugation-dependent bioactivation of foreign compounds. Adv Pharmacol 271-16
5. Mannervik B, Danielson UH 1988 Glutathione transferases - structure and catalytic activity. CRC Crit Rev Biochem 23:283-337
6. Bock KW 1991 Roles of UDP-glucuronosyltransferases in chemical carcinogenesis. Crit Rev Biochem Mol Biol 26:129-150
7. Coughtrie MW 2002 Sulfation through the looking glass - recent advances in sulfotransferase research for the curious. Pharmacogenomics J 2:297-308
8. Meijer J, DePierre JW 1988 Cytosolic epoxide hydrolase. Chem Biol Interact 64:207-249
9. Cadenas E 1995 Antioxidant and prooxidant functions of DT-diaphorase in quinone metabolism. Biochem Pharmacol 49:127-140
10. Wattenberg LW 1978 Inhibitors of chemical carcinogenesis. Adv Cancer Res 26:197-226
11. Prestera T, Zhang Y, Spencer SR, Wilczak CA, Talalay P 1993 The electrophile counterattack response: protection against neoplasia and toxicity. Adv Enzyme Regul 33:281-296
12. Benson AM, Batzinger RP, Ou SY, Bueding E, Cha YN, Talalay P 1978 Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo(a)pyrene by dietary antioxidants. Cancer Res 38:4486-4495
13. Pantuck EJ, Pantuck CB, Garland WA, Min BH, Wattenberg LW, Anderson KE, Kappas A, Conney AH 1979 Stimulatory effect of brussels sprouts and cabbage on human drug metabolism. Clin Pharmacol Ther 25:88-95
14. Benson AM, Hunkeler MJ, Talalay P 1980 Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity. Proc Natl Acad Sci USA 77:5216-5220
15. Wattenberg LW 1985 Chemoprevention of cancer. Cancer Res 45:1-8
16. Rushmore TH, Morton MR, Pickett CB 1991 The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem 266:11632-11639
17. Wasserman WW, Fahl WE 1997 Functional antioxidant responsive elements. Proc Natl Acad Sci USA 94:5361-5366
18. Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, Oyake T, Hayashi N, Satoh K, Hatayama I, Yamamoto M, Nabeshima Y1997 An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 236:313-322
19. Nicholson RI, McClelland RA, Robertson JF, Gee J M 1999 Involvement of steroid hormone and growth factor cross-talk in endocrine response in breast cancer. Endocr Relat Cancer 6:373-387
20. Paech K, Webb P, Kuiper GG, Nilsson S, Gustafsson J, Kushner PJ, Scanlan TS 1997 Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites. Science 277:1508-1510
21. Cavalieri E, Frenkel K, Liehr JG, Rogan E, Roy D 2000 Estrogens as endogenous genotoxic agents-DNA adducts and mutations. J Natl Cancer Inst Monogr 27:75-93
22. Liehr JG 1990 Genotoxic effects of estrogens. Mutat Res 238:269-276
23. Montano MM, Katzenellenbogen BS 1997 The quinone reductase gene: a unique estrogen receptor-regulated gene that is activated by antiestrogens. Proc Natl Acad Sci USA 94:2581-2586
24. Montano MM, Jaiswal AK, Katzenellenbogen BS 1998 Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-a and estrogen receptor-β. J Biol Chem 273:25443-25449
25. Montano MM, Wittmann BM, Bianco NR 2000 Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity. J Biol Chem 275:34306-34313
26. Oesterreich S, Zhang P, Guler RL, Sun X, Curran EM, Welshons WV, Osborne CK, Lee AV 2001 Re-expression of estrogen receptor α in estrogen receptor α-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth. Cancer Res 61:5771-5777
27. Jin Z, MacDonald RS 2002 Soy isoflavones increase latency of spontaneous mammary tumors in mice. J Nutr 132:3186-3190
28. Curran EM, Berghaus LJ, Vernetti NJ, Saporita AJ, Lubahn DB, Estes DM 2001 Natural killer cells express estrogen receptor-α and estrogen receptor-α and can respond to estrogen via a non-estrogen receptor-α-mediated pathway. Cell Immunol 214:12-20
29. Habig WH, Pabst MJ, Jakoby WB 1974 Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130-7139
30. Hayes JD, Pulford DJ 1995 The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 30:445-600
31. Couse JF, Lindzey J, Grandien K, Gustafesson J-A, Korach KS 1997 Tissue distribution and quantitative analysis of estrogen receptor-α (ERα) and estrogen receptor-β (ERβ) messenger ribonucleic acid in the wild-type and ERα-knockout. Endocrinology 138:4613-4621
32. Offner H, Adlard K, Zamora A, Vandenbark AA 2000 Estrogen potentiates treatment with T-cell receptor protein of female mice with experimental encephalomyelitis. J Clin Invest 105:1465-1472
33. Gruber CJ, Tschugguel W, Schneeberger C, Huber JC 2002 Production and actions of estrogens. N Engl J Med 346:340-352
34. Chan K, Lu R, Chang JC, Kan YW 1996 NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. Proc Natl Acad Sci USA 93:13943-13948
35. Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW 2001 Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci USA 98:3410-3415
36. Bianco NR, Perry G, Smith MA, Templeton DJ, Montano MM 2003 Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Mol Endocrinol 17:1344-1355
37. Saville B, Wormke M, Wang F, Nguyen T, Enmark E, Kuiper G, Gustafsson JA, Safe S 2000 Ligand-, cell-, and estrogen receptor subtype (α/β)- dependent activation at GC-rich (Sp1) promoter elements. J Biol Chem 275:5379-5387
38. Kedar RP, Bourne TH, Powles TJ, Collins WP, Ashley SE, Cosgrove DO, Campbell S 1994 Effects of tamoxifen on uterus and ovaries of postmenopausal women in a randomised breast cancer prevention trial. Lancet 343:1318-1321
39. Lee JM, Anderson PC, Padgitt JK, Hanson JM, Waters CM, Johnson JA 2003 Nrf2, not the estrogen receptor, mediates catechol estrogen-induced activation of the antioxidant responsive element. Biochim Biophys Acta 1629:92-101