Inhibition of dopamine transport and binding of [3H] spiperone to dopamine D2 receptor by acute Pb - Toxicity in vivo

Folia Neuropathologica

Volumn 37, Issue 4, 1999, Pages

  Sulkowski, Grzegorz ^a,b   Da̧browska Bouta, Beata ^a,b   Waśkiewicz, Jolanta ^a,b   Rafałowska, Urszula ^a,b  

^a POLISH ACADEMY OF SCIENCES   (Poland)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Acute lead toxicity; Dopamine transport; Receptor

Indexed keywords

DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; LEAD; SPIPERONE;

ACUTE DISEASE; ANIMAL; ARTICLE; BINDING COMPETITION; BLOOD; BRAIN; DRUG ANTAGONISM; LEAD POISONING; MALE; METABOLISM; PHYSIOLOGY; RAT; TRANSPORT AT THE CELLULAR LEVEL; WISTAR RAT;

ACUTE DISEASE; ANIMALS; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; BRAIN; DOPAMINE; DOPAMINE ANTAGONISTS; LEAD; LEAD POISONING; MALE; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; SPIPERONE;

EID: 0347651389     PISSN: 00283894     EISSN: 1509572X     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Booth RFG, Clark JB: A rapid method for the preparation of relatively pure metabolically synaptosomes from rat brain. Biochem. J., 1978, 176, 365-370.
2. Bradbury MW, Band Deane R: Permeability of the blood-brain barrier to lead. Neurotoxicology, 1993, 14, (2-3) 131-136.
3. Davis JM, Elias RW, Grant LD: Current issues in lead expousure and regulation of lead. Neurotoxicology, 1993, 14, (2-3): 15-28.
4. Deutsch C, Drown C, Rafalowska U, Silver IA: Synaptosomes from rat brain (morphology, conpartmentation and transmembrane pH and electrical gradients). J. Neurochem, 1981, 36, 2063-2072.
5. Da̧browska-Bouta B, Strużyńska L, Rafałowska U: Effect of acute and chronic lead exposure on the level of sulfhydryl groups in rat brain. Acta Neurobiol. Exp, 1996, 56, 233-236.
6. Gayer RA, Chisolm J J: Lead in metabolic contamination and human health. DH. K. Lee, Academia Press. NY. and London, 1972, 57-95.
7. Goldstein GW, Asbury AK, Diamoud I: Pathogenesis of lead encephalopathy. Uptake of lead and reaction of brain capillaries. Arch. Neurol, 1974, 31, 382-389.
8. Holtzman D, De Vries C, Ngungen H, Olsen I and Bensek V: Maturation of resistance to lead encephalopathy: Cellular and subcellular mechanisms. NeuroToxicology, 1984, 5, 97-124.
9. Iaber M, Robinson SW, Missole C, Caron MG: Dopamine receptors and brain function. Neuropharmacology, 1996, 35, 1503-1519.
10. Jablłońska L, Walski M, Rafałowska U: Lead as an inductor of some morphological and functional changes in synaptosomes from rat brain.Cell Molec. Neurobiol, 1994, 14, 700-709.
11. Klimek V, Nielsen M: Chronic treatment with antidepressents decreases the number [3H] SCH 23390 binding sites in the rat striatum and limbic system. European J. Pharmacology, 1987, 139, 163-169.
12. Kolton L, Yoari Y, Israel J: States of action of lead on spontaneous transmitter release from motor nerve terminals. Med Sci, 1982, 18, 165-170.
13. Krigman MR, Hogan EL: Effect of lead intoxication on the postnatal growth of the rat nervous system. Ensir. Hlth. Exp. Issue, 1974, 7, 187-189 (1974).
14. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with Folin phenol reagent. J. Biol. Chem, 1951, 193, 265-275.
15. Pastuszko A, Wilson DF, Erecińska M: Neurotransmitter metabolism in rat brain synaptosomes, Effect of anoxia and pH. J. Neurochem, 1982, 38, 1657-1667.
16. Pollard HB Pappas GD: Veratridine-activated release of adenosine-5;-triphosphate from synaptosomes: evidence for calcium dependence and blockade by tetrodotoxin. Biochem. Biophys. Res. Commun, 1979, 88, 1315-1321.
17. Rafałowska U, Erecińska M, Wilson D: Energy metabolism in rat brain synaptosomes from nembutal-anesthetized and nonanesthetized animals. J. Neurochem, 1980, 34, 1380-1386.
18. Rafałowska U, Zitting A, Savdainen H: Metabolic changes in rat brain synaptosomes after exposure to sulfide in vivo. Toxicology Letters, 1986, 34,193-200.
19. Silbergeld EK: Interaction of lead and Ca on the synaptosomal uptake of dopamine and choline. Life Science, 1977, 20, 309-318.
20. Silbergeld EK, Fales IT, Goldberg AM: The effects of inorganic lead on the neuromuscular function. Neuropharmacology, 1974, 13, 795-801.
21. Strużyńska L, Rafałowska U: The effect of lead on dopamine, GABA and histidine spontaneous and KCl-dependent releases from rat brain synaptosomes. Acta Neurobiol. Exp, 1994, 54, 201-207.
22. Strużyńska L, Walski M, Gadomski R, Da̧browska-Bouta B, Rafałowska U: Lead-induced abnormalities in blood-brain barrier permeability in experimental chronic toxicity. Mol. Chem. Neuropatol, 1997, 31, 207-224.
23. Thomas JA, Dallenbaek FD, Thomas M J: The disturbation of radioactive lead (210Pb) in the cerebellum of developing rats. Pathology, 1973, 109, 45-50.
24. Troeger MB, Rafałowska U, Erecińska M: Effect oleate on neurotransmitter transport and other plasma membrane functions in rat brain synaptosomes. J. Neurochem, 1984, 42, 1735-1742.
25. B binding caused by acute and chronic lead administration. Acta Neurobiol. Exp, 1996, 56, 227-231.