메뉴 건너뛰기




Volumn 15, Issue 12, 2003, Pages 1178-1184

The inhibition of inducible nitric oxide synthase reverts arthritic-induced decrease in pituitary growth hormone mRNA but not in liver insulin-like growth factor I mRNA expression

Author keywords

Aminoguanidine; Arthritis; GH; IGF I; Somatostatin

Indexed keywords

AMINOGUANIDINE; FREUND ADJUVANT; GROWTH HORMONE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SOMATOMEDIN C; SOMATOSTATIN;

EID: 0347382585     PISSN: 09538194     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2003.01117.x     Document Type: Article
Times cited : (6)

References (54)
  • 2
    • 0026786624 scopus 로고
    • Stress and hypothalamic-pituitary-adrenal axis: Acute, chronic and immunological activation
    • Harbuz MS, Lightman SL. Stress and hypothalamic-pituitary-adrenal axis: acute, chronic and immunological activation. J Endocrinol 1992; 134: 327-339.
    • (1992) J. Endocrinol. , vol.134 , pp. 327-339
    • Harbuz, M.S.1    Lightman, S.L.2
  • 3
    • 0034094261 scopus 로고    scopus 로고
    • IGF-I and IGF-I-binding proteins in rats with adjuvant-induced arthritis given recombinant human growth hormone
    • Ibáñez de Cáceres I, Villanúa MA, Soto L, Martín AI, López-Calderón A. IGF-I and IGF-I-binding proteins in rats with adjuvant-induced arthritis given recombinant human growth hormone. J Endocrinol 2000; 165: 537-544.
    • (2000) J. Endocrinol. , vol.165 , pp. 537-544
    • Ibáñez de Cáceres, I.1    Villanúa, M.A.2    Soto, L.3    Martín, A.I.4    López-Calderón, A.5
  • 4
    • 0026465226 scopus 로고
    • Hyperprolactinemia in hypophysectomized or intact male rats and the development of adjuvant arthritis
    • Neidhart M, Flückiger EW. Hyperprolactinemia in hypophysectomized or intact male rats and the development of adjuvant arthritis. Immunology 1992; 77: 449-455.
    • (1992) Immunology , vol.77 , pp. 449-455
    • Neidhart, M.1    Flückiger, E.W.2
  • 5
    • 0026455104 scopus 로고
    • Glucocorticoid-mediated responses of plasma ACTH and anterior pituitary pro-opiomelanocortin, growth hormone and prolactin mRNAs during adjuvant-induced arthritis in the rat
    • Stephanou A, Sarlis NJ, Knight RA, Lightman SL, Chowdrey HS. Glucocorticoid-mediated responses of plasma ACTH and anterior pituitary pro-opiomelanocortin, growth hormone and prolactin mRNAs during adjuvant-induced arthritis in the rat. J Mol Endocrinol 1992; 9: 273-281.
    • (1992) J. Mol. Endocrinol. , vol.9 , pp. 273-281
    • Stephanou, A.1    Sarlis, N.J.2    Knight, R.A.3    Lightman, S.L.4    Chowdrey, H.S.5
  • 6
    • 0033536566 scopus 로고    scopus 로고
    • Chronic inflammation inhibits GH secretion and alters the serum insulin-like growth factor system in rats
    • López-Calderón A, Soto L, Martín AI. Chronic inflammation inhibits GH secretion and alters the serum insulin-like growth factor system in rats. Life Sci 1999; 65: 2049-2060.
    • (1999) Life Sci. , vol.65 , pp. 2049-2060
    • López-Calderón, A.1    Soto, L.2    Martín, A.I.3
  • 9
    • 0031963218 scopus 로고    scopus 로고
    • Changes in nitric oxide synthase isoforms in the spinal cord of rat following induction of chronic arthritis
    • Wu J, Ling Q, Lu Y, Willis WD, Westlund KN. Changes in nitric oxide synthase isoforms in the spinal cord of rat following induction of chronic arthritis. Exp Brain Res 1998; 118: 457-465.
    • (1998) Exp. Brain Res. , vol.118 , pp. 457-465
    • Wu, J.1    Ling, Q.2    Lu, Y.3    Willis, W.D.4    Westlund, K.N.5
  • 10
    • 0030780758 scopus 로고    scopus 로고
    • Perspectives series: Nitric oxide and nitric oxide synthases. Inducible nitric oxide synthase: What difference does it make?
    • Nathan C. Perspectives series: nitric oxide and nitric oxide synthases. Inducible nitric oxide synthase: what difference does it make? J Clin Invest 1997; 100: 2417-2423.
    • (1997) J. Clin. Invest. , vol.100 , pp. 2417-2423
    • Nathan, C.1
  • 13
    • 0027143823 scopus 로고
    • Evidence that nitric oxide may mediate the ovarian steroid-steroid-induced luteinizing hormone surge: Involvement of excitatory amino acids
    • Bonavera J, Sahu A, Kalra P, Kalra S. Evidence that nitric oxide may mediate the ovarian steroid-steroid-induced luteinizing hormone surge: involvement of excitatory amino acids. Endocrinology 1993; 133: 2481-2487.
    • (1993) Endocrinology , vol.133 , pp. 2481-2487
    • Bonavera, J.1    Sahu, A.2    Kalra, P.3    Kalra, S.4
  • 14
    • 0030474214 scopus 로고    scopus 로고
    • Influence of nitric oxide on hypoglycemia- or angiotensin II-stimulated ACTH and GH secretion in normal men
    • Volpi R, Chiodera P, Caffarri G, Vescovi P, Capretti L, Gatti C, Coiro V. Influence of nitric oxide on hypoglycemia- or angiotensin II-stimulated ACTH and GH secretion in normal men. Neuropeptides 1996; 30: 528-532.
    • (1996) Neuropeptides , vol.30 , pp. 528-532
    • Volpi, R.1    Chiodera, P.2    Caffarri, G.3    Vescovi, P.4    Capretti, L.5    Gatti, C.6    Coiro, V.7
  • 18
    • 0032698396 scopus 로고    scopus 로고
    • Nitric oxide stimulates growth hormone secretion in vitro through a calcium- and cyclic guanosine monophosphate-independent mechanism
    • Pinilla L, Tena-Sempere M, Aguilar E. Nitric oxide stimulates growth hormone secretion in vitro through a calcium- and cyclic guanosine monophosphate-independent mechanism. Horm Res 1999; 51: 242-247.
    • (1999) Horm. Res. , vol.51 , pp. 242-247
    • Pinilla, L.1    Tena-Sempere, M.2    Aguilar, E.3
  • 19
    • 0030923706 scopus 로고    scopus 로고
    • Involvement of nitric oxide in the interferon-gamma-induced inhibition of growth hormone and prolactin secretion in anterior pituitary cell cultures
    • Vankelecom H, Matthys P, Denef C. Involvement of nitric oxide in the interferon-gamma-induced inhibition of growth hormone and prolactin secretion in anterior pituitary cell cultures. Mol Cell Endocrinol 1997; 129: 157-167.
    • (1997) Mol. Cell Endocrinol. , vol.129 , pp. 157-167
    • Vankelecom, H.1    Matthys, P.2    Denef, C.3
  • 21
    • 0030029925 scopus 로고    scopus 로고
    • Biphasic changes in behavioural, endocrine and sympathetic systems in adjuvant arthritis in Lewis rats
    • Tanaka H, Ueta Y, Yamashita U, Kannan M, Yamashita H. Biphasic changes in behavioural, endocrine and sympathetic systems in adjuvant arthritis in Lewis rats. Brain Res Bull 1996; 39: 33-37.
    • (1996) Brain Res. Bull. , vol.39 , pp. 33-37
    • Tanaka, H.1    Ueta, Y.2    Yamashita, U.3    Kannan, M.4    Yamashita, H.5
  • 23
    • 0035709008 scopus 로고    scopus 로고
    • A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite
    • Miranda KM, Espey MG, Wink DA. A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide 2001; 5: 62-71.
    • (2001) Nitric Oxide , vol.5 , pp. 62-71
    • Miranda, K.M.1    Espey, M.G.2    Wink, D.A.3
  • 24
    • 0031772959 scopus 로고    scopus 로고
    • Effects of endotoxin lipopolysaccharide administration on the somatotropic axis
    • Soto L, Martín AI, Millán S, Vara E, López-Calderón A. Effects of endotoxin lipopolysaccharide administration on the somatotropic axis. J Endocrinol 1998; 159: 239-246.
    • (1998) J. Endocrinol. , vol.159 , pp. 239-246
    • Soto, L.1    Martín, A.I.2    Millán, S.3    Vara, E.4    López-Calderón, A.5
  • 25
    • 0026699261 scopus 로고
    • Survival of purkinje cells in cerebellar cultures is increased by insulin-growth factor I
    • Torres-Alemán I, Pons S, Santos-Benito FF. Survival of purkinje cells in cerebellar cultures is increased by insulin-growth factor I. Eur J Neurosci 1992; 4: 864-869.
    • (1992) Eur. J. Neurosci. , vol.4 , pp. 864-869
    • Torres-Alemán, I.1    Pons, S.2    Santos-Benito, F.F.3
  • 26
    • 0023298435 scopus 로고
    • Molecular cloning of rat insulin-like growth factor I complementary deoxyribonucleic acids: Differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissues
    • Roberts CT, Lasky SR, Lowe WL, Seaman WT, LeRoith D. Molecular cloning of rat insulin-like growth factor I complementary deoxyribonucleic acids: differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissues. Mol Endocrinol 1987; 1: 243-248.
    • (1987) Mol. Endocrinol. , vol.1 , pp. 243-248
    • Roberts, C.T.1    Lasky, S.R.2    Lowe, W.L.3    Seaman, W.T.4    LeRoith, D.5
  • 27
    • 0024712404 scopus 로고
    • The growth hormone-binding protein in rat serum is an alternatively spliced form of the rat growth hormone receptor
    • Baumbach WR, Horner DL, Logan JS. The growth hormone-binding protein in rat serum is an alternatively spliced form of the rat growth hormone receptor. Genes Dev 1989; 3: 1199-1205.
    • (1989) Genes Dev. , vol.3 , pp. 1199-1205
    • Baumbach, W.R.1    Horner, D.L.2    Logan, J.S.3
  • 28
    • 0020604271 scopus 로고
    • Rat pre-prosomatostatin structure and processing by microsomal membranes
    • Goodman RH, Aron DC, Roos BA. Rat pre-prosomatostatin structure and processing by microsomal membranes. J Biol Chem 1983; 258: 5570-5573.
    • (1983) J. Biol. Chem. , vol.258 , pp. 5570-5573
    • Goodman, R.H.1    Aron, D.C.2    Roos, B.A.3
  • 29
    • 0017770140 scopus 로고
    • Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone
    • Peter HS, Shine J, Martial JA, Baxter JD, Goodman HM. Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone. Nature 1977; 270: 486-494.
    • (1977) Nature , vol.270 , pp. 486-494
    • Peter, H.S.1    Shine, J.2    Martial, J.A.3    Baxter, J.D.4    Goodman, H.M.5
  • 30
    • 0030060622 scopus 로고    scopus 로고
    • The increase in growth hormone secretion in experimentally induced arthritic rats is an adaptive process involved in the regulation of inflammation
    • Bluet-Pajot MT, Mounier F, Slama A, Videau C, Kordon C, Epelbaum J, Calvino B. The increase in growth hormone secretion in experimentally induced arthritic rats is an adaptive process involved in the regulation of inflammation. Neuroendocrinology 1996; 63: 85-92.
    • (1996) Neuroendocrinology , vol.63 , pp. 85-92
    • Bluet-Pajot, M.T.1    Mounier, F.2    Slama, A.3    Videau, C.4    Kordon, C.5    Epelbaum, J.6    Calvino, B.7
  • 31
    • 0024212413 scopus 로고
    • Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion
    • Alba-Roth J, Muller OA, Schoopohl J, von Werder K. Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion. J Clin Endocrinol Metab 1988; 67: 1186-1189.
    • (1988) J. Clin. Endocrinol. Metab. , vol.67 , pp. 1186-1189
    • Alba-Roth, J.1    Muller, O.A.2    Schoopohl, J.3    von Werder, K.4
  • 32
    • 0025372164 scopus 로고    scopus 로고
    • Arginine potentiates the GHRH- but not the pyridostigmine-induced GH secretion in normal short children: Further evidence for a somatostatin suppressing effect of arginine
    • Ghigo E, Bellone J, Mazza E, Imperiale E, Procopio M, Valente F, Lalla R, De Sanctis C, Camanni F. Arginine potentiates the GHRH- but not the pyridostigmine-induced GH secretion in normal short children: further evidence for a somatostatin suppressing effect of arginine. Clin Endocrinol 1996; 32: 763-767.
    • (1996) Clin. Endocrinol. , vol.32 , pp. 763-767
    • Ghigo, E.1    Bellone, J.2    Mazza, E.3    Imperiale, E.4    Procopio, M.5    Valente, F.6    Lalla, R.7    De Sanctis, C.8    Camanni, F.9
  • 33
    • 0028009750 scopus 로고
    • Growth hormone-releasing factor increases somatostatin release and mRNA levels in the rat periventricular nucleus via nitric oxide by activation of guanylate cyclase
    • Aguila MC. Growth hormone-releasing factor increases somatostatin release and mRNA levels in the rat periventricular nucleus via nitric oxide by activation of guanylate cyclase. Proc Natl Acad Sci USA 1994; 91: 782-786.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 782-786
    • Aguila, M.C.1
  • 34
    • 0030016419 scopus 로고    scopus 로고
    • Evidence that brain nitric oxide synthase is the major nitric oxide synthase isoform in the hypothalamus of the adult female rat and that nitric oxide potently regulates hypothalamic cGMP levels
    • Bhat G, Mahesh VB, Aguan K, Brann DW. Evidence that brain nitric oxide synthase is the major nitric oxide synthase isoform in the hypothalamus of the adult female rat and that nitric oxide potently regulates hypothalamic cGMP levels. Neuroendocrinology 1996; 64: 93-102.
    • (1996) Neuroendocrinology , vol.64 , pp. 93-102
    • Bhat, G.1    Mahesh, V.B.2    Aguan, K.3    Brann, D.W.4
  • 35
    • 0035570032 scopus 로고    scopus 로고
    • Effects of aminoguanidine and meloxicam on nitric oxide and prostaglandin E production induced by lipopolysaccharide in the hypothalamus and anterior pituitary of the rat
    • Mohn C, Lomniczi A, Faletti A, Scorticati C, Elverdin JC, McCann SM, Rettori V. Effects of aminoguanidine and meloxicam on nitric oxide and prostaglandin E production induced by lipopolysaccharide in the hypothalamus and anterior pituitary of the rat. Neuroimmunomodulation 2001; 9: 276-285.
    • (2001) Neuroimmunomodulation , vol.9 , pp. 276-285
    • Mohn, C.1    Lomniczi, A.2    Faletti, A.3    Scorticati, C.4    Elverdin, J.C.5    McCann, S.M.6    Rettori, V.7
  • 36
    • 0029143450 scopus 로고
    • Endotoxin-induced suppression of the somatotropic axis is mediated by interleukin-1 beta and corticotropin-releasing factor in the juvenile rat
    • Peisen JN, McDonnell KJ, Mulroney SE, Lumpkin MD. Endotoxin-induced suppression of the somatotropic axis is mediated by interleukin-1 beta and corticotropin-releasing factor in the juvenile rat. Endocrinology 1995; 136: 3378-3390.
    • (1995) Endocrinology , vol.136 , pp. 3378-3390
    • Peisen, J.N.1    McDonnell, K.J.2    Mulroney, S.E.3    Lumpkin, M.D.4
  • 37
    • 0026006112 scopus 로고
    • Interleukin-1 beta modulates the acute release of growth hormone-releasing hormone and somatostatin from rat hypothalamus in vitro, whereas tumor necrosis factor and interleukin-6 have no effect
    • Honegger J, Spagnoli A, D'Urso R, Navarra P, Tsagarakis S, Besser GM, Grossman AB. Interleukin-1 beta modulates the acute release of growth hormone-releasing hormone and somatostatin from rat hypothalamus in vitro, whereas tumor necrosis factor and interleukin-6 have no effect. Endocrinology 1991; 129: 1275-1282.
    • (1991) Endocrinology , vol.129 , pp. 1275-1282
    • Honegger, J.1    Spagnoli, A.2    D'Urso, R.3    Navarra, P.4    Tsagarakis, S.5    Besser, G.M.6    Grossman, A.B.7
  • 38
    • 0035968064 scopus 로고    scopus 로고
    • Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain
    • Cash D, Beech JS, Rayne RC, Bath PM, Meldrum BS, Williams SC. Neuroprotective effect of aminoguanidine on transient focal ischaemia in the rat brain. Brain Res 2001; 905: 91-103.
    • (2001) Brain Res. , vol.905 , pp. 91-103
    • Cash, D.1    Beech, J.S.2    Rayne, R.C.3    Bath, P.M.4    Meldrum, B.S.5    Williams, S.C.6
  • 39
    • 0037294819 scopus 로고    scopus 로고
    • Neuroprotection by aminoguanidine after lateral fluid-percussive brain injury in rats: A combined magnetic resonance imaging, histopathologic and functional study
    • Lu J, Moochhala S, Shirhan M, Chye Ng K, Ling Teo A, Hong Tan M, Lei Moore X, Cheong Wong M, Ang Ling E. Neuroprotection by aminoguanidine after lateral fluid-percussive brain injury in rats: a combined magnetic resonance imaging, histopathologic and functional study. Neuropharmacology 2003; 44: 253-263.
    • (2003) Neuropharmacology , vol.44 , pp. 253-263
    • Lu, J.1    Moochhala, S.2    Shirhan, M.3    Chye Ng, K.4    Ling Teo, A.5    Hong Tan, M.6    Lei Moore, X.7    Cheong Wong, M.8    Ang Ling, E.9
  • 41
    • 0035968073 scopus 로고    scopus 로고
    • Comibination of inflammatory cytokines increases nitrite and nitrate levels in the paraventricular nucleus of conscious rat
    • Wakita T, Shintani F, Yagi G, Asai M, Nozawa S. Comibination of inflammatory cytokines increases nitrite and nitrate levels in the paraventricular nucleus of conscious rat. Brain Res 2001; 905: 12-20.
    • (2001) Brain Res. , vol.905 , pp. 12-20
    • Wakita, T.1    Shintani, F.2    Yagi, G.3    Asai, M.4    Nozawa, S.5
  • 42
    • 0031751425 scopus 로고    scopus 로고
    • Leptin alters the response of the growth hormone releasing factor-growth hormone-insulin-like growth factor-I axis to fasting
    • LaPaglia N, Steiner J, Kirsteins L, Emanuele M, Emanuele N. Leptin alters the response of the growth hormone releasing factor-growth hormone-insulin-like growth factor-I axis to fasting. J Endocrinol 1998; 159: 79-83.
    • (1998) J. Endocrinol. , vol.159 , pp. 79-83
    • LaPaglia, N.1    Steiner, J.2    Kirsteins, L.3    Emanuele, M.4    Emanuele, N.5
  • 43
    • 0029886191 scopus 로고    scopus 로고
    • Gene expression of the receptor for growth-hormone-releasing hormone is physiologically regulated by glucocorticoids and estrogen
    • Lam KSL, Lee MF, Tam SP, Srivastava G. Gene expression of the receptor for growth-hormone-releasing hormone is physiologically regulated by glucocorticoids and estrogen. Neuroendocrinology 1996; 63: 475-480.
    • (1996) Neuroendocrinology , vol.63 , pp. 475-480
    • Lam, K.S.L.1    Lee, M.F.2    Tam, S.P.3    Srivastava, G.4
  • 44
    • 0032458647 scopus 로고    scopus 로고
    • Percoll density gradient-enriched populations of rat pituitary cells: Interleukin 6 secretion, proliferative activity, and nitric oxide synthase expression
    • Qian X, Jin L, Lloyd RV. Percoll density gradient-enriched populations of rat pituitary cells: Interleukin 6 secretion, proliferative activity, and nitric oxide synthase expression. Endocr Pathol 1998; 9: 339-346.
    • (1998) Endocr. Pathol. , vol.9 , pp. 339-346
    • Qian, X.1    Jin, L.2    Lloyd, R.V.3
  • 45
    • 0034989899 scopus 로고    scopus 로고
    • Spontaneous and receptor-controlled soluble guanylyl cyclase activity in anterior pituitary cells
    • Kostic TS, Andric SA, Stojilkovic SS. Spontaneous and receptor-controlled soluble guanylyl cyclase activity in anterior pituitary cells. Mol Endocrinol 2001; 15: 1010-1022.
    • (2001) Mol. Endocrinol. , vol.15 , pp. 1010-1022
    • Kostic, T.S.1    Andric, S.A.2    Stojilkovic, S.S.3
  • 47
    • 0026484282 scopus 로고
    • Involvement of nitric oxide in growth hormone (GH)-releasing hormone-induced GH secretion in rat pituitary cells
    • Kato M. Involvement of nitric oxide in growth hormone (GH)-releasing hormone-induced GH secretion in rat pituitary cells. Endocrinology 1992; 131: 2133-2138.
    • (1992) Endocrinology , vol.131 , pp. 2133-2138
    • Kato, M.1
  • 48
  • 49
    • 0029662183 scopus 로고    scopus 로고
    • Involvement of endogenous nitric oxide in the control of pituitary responsiveness to different elicitors of growth hormone release in prepubertal rats
    • Tena-Sempere M, Pinilla L, González D, Aguilar E. Involvement of endogenous nitric oxide in the control of pituitary responsiveness to different elicitors of growth hormone release in prepubertal rats. Neuroendocrinology 1996; 64: 146-152.
    • (1996) Neuroendocrinology , vol.64 , pp. 146-152
    • Tena-Sempere, M.1    Pinilla, L.2    González, D.3    Aguilar, E.4
  • 50
    • 0034093847 scopus 로고    scopus 로고
    • Evidence that nitric oxide is involved in the regulation of growth hormone secretion in goldfish
    • Uretsky AD, Chang JP. Evidence that nitric oxide is involved in the regulation of growth hormone secretion in goldfish. General Comp Endocrinol 2000; 118: 461-470.
    • (2000) General Comp. Endocrinol. , vol.118 , pp. 461-470
    • Uretsky, A.D.1    Chang, J.P.2
  • 51
    • 0034278874 scopus 로고    scopus 로고
    • Nitric oxide biphasically modulates GH secretion in cultured cells of GH-secreting human pituitary adenomas
    • Bocca L, Valenti S, Cuttica CM, Spaziante R, Giordano G, Giusti M. Nitric oxide biphasically modulates GH secretion in cultured cells of GH-secreting human pituitary adenomas. Minerva Endocrinol 2000; 25: 55-59.
    • (2000) Minerva Endocrinol. , vol.25 , pp. 55-59
    • Bocca, L.1    Valenti, S.2    Cuttica, C.M.3    Spaziante, R.4    Giordano, G.5    Giusti, M.6
  • 52
    • 1842834977 scopus 로고    scopus 로고
    • A DNA microarray study of nitric oxide-induced genes in mouse hepatocytes: Implications for hepatic heme oxygenase-1 expression in ischemia/repefusion
    • Zamora R, Vodovotz Y, Aulak KS, Kim PK, Kane JM, Alarcon L, Stuehr DJ, Billiar TR. A DNA microarray study of nitric oxide-induced genes in mouse hepatocytes: implications for hepatic heme oxygenase-1 expression in ischemia/repefusion. Nitric Oxide 2002; 7: 165-186.
    • (2002) Nitric Oxide , vol.7 , pp. 165-186
    • Zamora, R.1    Vodovotz, Y.2    Aulak, K.S.3    Kim, P.K.4    Kane, J.M.5    Alarcon, L.6    Stuehr, D.J.7    Billiar, T.R.8
  • 53
    • 0034960931 scopus 로고    scopus 로고
    • Effects of aminoguanidine on nitric oxide production induced by inflammatory cytokines and endotoxin in cultures rat hepatocytes
    • Zhang GL, Wang YH, Teng HI, Lin ZB. Effects of aminoguanidine on nitric oxide production induced by inflammatory cytokines and endotoxin in cultures rat hepatocytes. World J Gastroenterol 2001; 7: 331-334.
    • (2001) World J. Gastroenterol. , vol.7 , pp. 331-334
    • Zhang, G.L.1    Wang, Y.H.2    Teng, H.I.3    Lin, Z.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.