Gene Expression of the Receptor for Growth-Hormone-Releasing Hormone Is Physiologically Regulated by Glucocorticoids and Estrogen

Neuroendocrinology

Volumn 63, Issue 6, 1996, Pages 475-480

  Lam, Karen S L ^a   Lee, Man Fong ^a   Tam, Sau Ping ^a   Srivastava, Gopesh ^b  

^a Departments of Medicine   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Adrenal steroids; Adrenalectomy; Castration; Gene expression; Gonadal steroids; Growth hormone; Growth hormone releasing hormone; Growth hormone releasing hormone receptor

Indexed keywords

CELL RECEPTOR; CORTICOSTEROID; DEXAMETHASONE; ESTRADIOL BENZOATE; ESTROGEN; GLUCOCORTICOID; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; GROWTH HORMONE RELEASING HORMONE RECEPTOR; MESSENGER RNA; UNCLASSIFIED DRUG;

ADENOHYPOPHYSIS; ADRENALECTOMY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA PROBE; DOSE RESPONSE; FEMALE; GENE EXPRESSION REGULATION; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE RELEASE; GROWTH RETARDATION; HORMONAL REGULATION; HYPOPHYSIS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; NORTHERN BLOTTING; OVARIECTOMY; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; WEIGHT GAIN;

ANIMALS; BLOTTING, NORTHERN; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGENS; GENE EXPRESSION; GLUCOCORTICOIDS; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROPEPTIDE; RECEPTORS, PITUITARY HORMONE-REGULATING HORMONE;

EID: 0029886191     PISSN: 00283835     EISSN: 14230194     Source Type: Journal    
DOI: 10.1159/000127075     Document Type: Article

References (26)

1. Martinoli MG, Pelletier G: Thyroid and glucocorticoid hormone regulation of rat pituitary growth hormone messenger ribonucleic acid as revealed by in situ hybridization, Endocrinology 1989;125:1246-1252.
2. Giustina A, Romanelli G, Candrina R, Giusti-na G: Growth hormone deficiency in patients with idiopathic adrcnocorticotropin deficiency resolves during glucocorticoid replacement, Endocrinology 1989;68:120-123.
3. Franz AG, Rabkin MT: Human growth hormone: Clinical measurement, response to hy-poglycaemiaand blunting by corticosteroids, N Engl J Med 1964;271:1375-1381.
4. Kaufmann S, Jones KL, Wehrenberg WB, Cull-er F: Inhibition by prednisone of growth hormone (GH) response to GH-releasing hormone in normal men, J Clin Endocrinol Metab 1988; 67:1258-1261.
5. Wehrenberg WB, Janowski BA, Piering AW, Culler F, Jones KL: Glucocorticoids, potent inhibitor and stimulator of growth hormone secretion, Endocrinology 1990; 136:3200— 3203.
6. Seifert H, Perrin M, Rivier J, Vale W: Growth hormone-releasing factor binding sites in rat anterior pituitary membrane homogenates: Modulation by glucocorticoids, Endocrinology 1985; 117:424-426.
7. Hansson JO, Ekberg S, Isaksson OGP, Eden S: Influence of gonadal steroids on age and sex-related secretory patterns of growth hormone in the rat, Endocrinology 1984; 114:1287— 1291.
8. Shulman DL, Sweetland M, Duckett G, Root AW: Effect of estrogen on the growth hormone (GH) secretory response to GH-releasing factor in the castrate adult female rat in vivo, Endocrinology 1987;120:1047-1051.
9. Barinaga M, Yamonoto G, Rivier C, Vale W, Evans R, Rosenfeld MG: Transcriptional regulation of growth hormone gene expression by growth hormone-releasing factor, Nature 1983; 306:84-85.
10. Lam KSL, Srivastava S, Tam SP: Divergent effccts of glucocorticoid on the gene expression of vasoactive intestinal peptide in the rat cerc-bal cortex and pituitary, Neuroendocrinology 1992:56:32-37.
11. Lam KSL, Srivastava G, Lechan RM, Lee T, Reichlin S: Estrogen regulates the gene expression of vasoactive intestinal peptide in the anterior pituitary, Neuroendocrinology 1990;52: 417-421.
12. Butcher RL, Collins WE, Fugo NW: Plasma concentrations of LH, FSH, prolactin, progesterone and estradiol-17-5 throughout the 4-day estrous cycle of the rat, Endocrinology 1974;94: 1704-1708.
13. Chomozynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocya-natc-phcnol-chloroform extraction, Anal Bio-chem 1987;162:156-159.
14. Mayo KE: Molecular cloning and expression of a pituitary-specific receptor of grow’th hormone releasing hormone, Mol Endocrinol 1992;6: 1734-1744.
15. Barbu V, Daultry F: Northern blot normalization with a 28S rRNA oligonucleotide probe, Nucleic Acids Res 1989:17:7115.
16. Godfrey PA, Mayo KE: Structure of the rat GHRH receptor gene and characterization of two receptor isoforms (abstract), 77th Annual Meeting of the Endocrine Society, Washington, 1995, pp 3-129.
17. Tamaki M, Sato M, Matsubara S, Takahara J: Effect of dexamethasone on GRH receptor gene expression in cultured rat anterior pituitary cells (abstract), 77th Annual Meeting of the Endocrine Society, Washington, pp 3-129.
18. Nakagawa K, Ishizuka T, Obara T, Matsubara M, Akikiwa K: Dichotomic action of glucocorticoids on growth hormone secretion, Acta Endocrinol (Copenh) 1987; 116:165-171.
19. Maiter D, Koenig J, Kaplan LM: Sexually dimorphic expression of the growth hormone releasing hormone gene is not mediated by circulating gonadal hormone in the adult rat, Endocrinology 1991;128:1701-1716.
20. Gertz BJ, Ganden DG, Baxter JD: Glucocorticoid control of rat growth hormone gene expression: Effect on cytoplasmic messenger ribonucleic acid production and degradation, Mol Biol 1991;38:1-15.
21. Treacy MN, Ryan F, Martin F: Functional glucocorticoid inducible enhancer activity in the 5'-flanking sequence of the rat growth hormone gene, J Steroid Biochem Mol Biol 1991:38:1-15.
22. Shull JD, Walent JH, Gorski J: Estradiol stimulates prolactin gene transcription in primary culture of rat anterior pituitary cells, J Steroid Biochem 1987;26:451-456.
23. Ho KY, Thomer MO, Krieg RJ Jr., Lau SK, Sinha YN, Johnson M L, Leong DA, Evans WS: Effects of gonadal steroids on somatotroph function in the rat: Analysis by the reverse hemolytic plaque assay, Endocrinology 1988; 123:1405-1411.
24. Baldino F, Fitzpatrick-McElligott S, O'Kanc TM, Gozes I: Hormonal regulation of somatostatin messenger RNA, Synapse 1988:2:317— 325.
25. Hertz P, Silbermann M, Even L, Hochberg Z: Effects of sex steroids on the response of cultured rat pituitary cells to growth hormone-releasing hormone and somatostatin, Endocrinology 1989;125:581-585.
26. Wehrenberg WB, Bergman DJ, Stagg L, Ndon J, Giustina A: Glucocorticoid inhibition of growth in rats: Partial reversal with somatostatin antibodies, Endocrinology 1990; 127:2705— 2708.