Cyclooxygenase-2 Induction by Bradykinin in Human Pulmonary Artery Smooth Muscle Cells Is Mediated by the Cyclic AMP Response Element through a Novel Autocrine Loop Involving Endogenous Prostaglandin E2, E-prostanoid 2 (EP2), and EP4 Receptors

Journal of Biological Chemistry

Volumn 278, Issue 50, 2003, Pages 49954-49964

  Bradbury, Dawn A ^a   Newton, Robert ^b   Zhu, Yong M ^a   El Haroun, Hala ^a   Corbett, Lisa ^a   Knox, Alan J ^a,c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c NOTTINGHAM CITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ELECTROPHORESIS; MUSCLE; PULMONARY DISEASES;

TRANSCRIPTIONAL MECHANISMS;

ENZYMES;

AUTOCRINE MOTILITY FACTOR RECEPTOR; BRADYKININ; CCAAT ENHANCER BINDING PROTEIN; CYCLOOXYGENASE 2; G PROTEIN COUPLED RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; LUCIFERASE; OLIGONUCLEOTIDE; PHOSPHOLIPASE A2; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN RECEPTOR EP4; PROSTANOID; PROSTANOID EP2; UNCLASSIFIED DRUG;

ARTERY MUSCLE; ARTICLE; BINDING SITE; CELL VIABILITY; CYCLIC AMP RESPONSIVE ELEMENT; ENZYME ACTIVITY; ENZYME INDUCTION; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MEDIATOR RELEASE; PRIORITY JOURNAL; PROMOTER REGION; PULMONARY ARTERY; REPORTER GENE; SMOOTH MUSCLE FIBER; TRANSCRIPTION REGULATION; VASCULAR DISEASE;

ARACHIDONIC ACID; BLOTTING, WESTERN; BRADYKININ; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLOOXYGENASE 2; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE DELETION; GENES, REPORTER; HUMANS; ISOENZYMES; LUCIFERASES; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MUSCLE, SMOOTH; PROMOTER REGIONS (GENETICS); PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PULMONARY ARTERY; RECEPTORS, PROSTAGLANDIN E; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0347379917     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307964200     Document Type: Article

References (32)

1. Barnes, P. J. (1992) Thorax 47, 979-983
2. Trifilieff, A., Da Silva, A., and Gies, J. P. (1993) Eur. Respir. J. 6, 576-587
3. Bhoola, K. D., Figueroa, C. D., and Worthy, K. (1992) Pharmacol. Rev. 44, 1-80
4. Marnett, L. J., Rowlinson, S. W., Goodwin, D. C., Kalgutkar, A. S., and Lanzo, C. A. (1999) J. Biol. Chem. 274, 22903-22906
5. Chandrasekharan N. V., Dai, H., Roos K. L., Evanson N. K., Tomsik, J., Elton TS, and Simmons, D. L. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 13926-13931
6. Bradbury, D. A., Newton, R., Zhu, Y. M., Stocks, J., Corbett, L., Holland, E. D., Pang, L. H., and Knox, A. J. (2002) Am. J. Physiol. Lung Cell Mol. Physiol 283, L717-L725
7. Newton, R., Kuitert, L. M., Bergmann, M., Adcock, I. M., and Barnes, P. J. (1997) Biochem. Biophys. Res. Commun. 237, 28-32
8. Schmedtje, J. F., Jr., Ji, Y. S., Liu, W. L., Dubois, R. N., and Runge, M. S. (1997) J. Biol. Chem. 272, 601-608
9. Saunders, M. A., Sansores-Garcia, L., Gilroy, D. W., and Wu, K. K. (2001) J. Biol. Chem. 276, 18897-18904
10. Pan, Z. K., Zuraw, B. L., Lung, C. C., Prossnitz, E. R., Browning, D. D., and Ye, R. D. (1996) J. Clin. Invest. 98, 2042-2049
11. Xie, P., Browning, D. D., Hay, N., Mackman, N., and Ye, R. D. (2000) J. Biol. Chem. 275, 24907-24914
12. Zhu, Y. M., Bradbury, D. A., Pang, L., and Knox, A. J. (2003) J. Biol. Chem. 278, 29366-29375
13. Okada, Y., Voznesensky, O., Herschman, H., Harrison, J., and Pilbeam, C. (2000) J. Cell. Biochem. 78, 197-209
14. Maruyama, T., Asada, M., Shiraishi, T., Sakata, K., Seki, A., Yoshida, H., Shinagawa, Y., Maruyama, T., Ohuchida, S., Nakai, H., Kondo, K., and Toda, M. (2001) Bioorg. Med. Chem. Lett. 11, 2033-2035
15. Tani, K., Naganawa, A., Ishida, A., Egashira, H., Sagawa, K., Harada, H., Ogawa, M., Maruyama, T., Ohuchida, S., Nakai, H., Kondo, K., and Toda, M. (2001) Bioorg. Med. Chem. Lett. 11, 2025-2028
16. Wen, F. Q., Watanabe, K., and Yoshida, M. (1998) Prostaglandins Leukot. Essent. Fatty Acids 59, 71-75
17. Gilman, A. G. (1970) Proc. Natl. Acad. Sci. U. S. A. 67, 305-312
18. Pang, L., and Knox, A. J. (1997) Am. J. Physiol. 273, L1132-L1140
19. Scott, M. G., Swan, C., Jobson, T. M., Rees, S., and Hall, I. P. (1999) Br. J. Pharmacol. 128, 721-729
20. Pyne, N. J., Tolan, D., and Pyne, S. (1997) Biochem. J. 328(Pt 2), 689-694
21. Negishi, M., Sugimoto, Y., and Ichikawa, A. (1993) Prog. Lipid Res. 32, 417-434
22. Coleman RA, Smith WL, and Narumiya, S. (1994) Pharmacol. Rev. 46, 205-229
23. Suzawa, T., Miyaura, C., Inada, M., Maruyama, T., Sugimoto, Y., Ushikubi, F., Ichikawa, A., Narumiya, S., and Suda, T. (2000) Endocrinology 141, 1554-1559
24. Huang ZF, Massey JB, and Via, D. P. (2000) Biochemical Pharmacology 59, 187-194
25. Tamura, M., Sebastian, S., Yang, S., Gurates, B., Fang, Z., and Bulun, S. E. (2002) J. Clin. Endocrinol. Metab. 87, 3263-3273
26. Yamamoto, K., Arakawa, T., Ueda, N., and Yamamoto, S. (1995) J. Biol. Chem. 52, 31315-31320
27. Thomas, B., Berenbaum, F., Humbert, L., Bian, H., Bereziat, G., Crofford, L., and Olivier, J. L. (2000) Eur. J. Biochem. 267, 6798-6809
28. Pan, Z. K., Ye, R. D., Christiansen, S. C., Jagels, M. A., Bokoch, G. M., and Zuraw, B. L. (1998) J. Immunol. 160, 3038-3045
29. Naraba, H., Ueno, A., Kosugi, Y., Yoshimura, M., Murakami, M., Kudo, I., and Oh-ishi, S. (1998) FEBS Lett. 435, 96-100
30. Inoue, H., Nanayama, T., Hara, S., Yokoyama, C., and Tanabe, T. (1994) FEBS Lett. 350, 51-54
31. Stevens, P. A., Pyne, S., Grady, M., and Pyne, N. J. (1994) Biochem. J. 297(Pt 1), 233-239
32. Knox, A. J., Corbett, L., Stocks, J., Holland, E., Zhu, Y. M., and Pang, L. (2001) FASEB J. 15, 2480-2488