Unidirectional Cross-tolerance from Levetiracetam to Carbamazepine in Amygdala-kindled Seizures

Epilepsia

Volumn 44, Issue 12, 2003, Pages 1487-1493

  Zhang, Zhang Jin ^a   Xing, Guo Qiang ^a   Russell, Shani ^a,b   Obeng, Kris ^b   Post, Robert M ^b  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Carbamazepine; Cross tolerance; Kindling; Levetiracetam; Rat

Indexed keywords

CARBAMAZEPINE; ETIRACETAM; SODIUM CHLORIDE;

AFTERDISCHARGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; DISEASE MODEL; DRUG CROSS TOLERANCE; DRUG EFFICACY; DRUG RESPONSE; ELECTRODE; KINDLING; LONG TERM CARE; MALE; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; RAT STRAIN; SEIZURE;

AMYGDALA; ANIMALS; ANTICONVULSANTS; CARBAMAZEPINE; DRUG TOLERANCE; ELECTROENCEPHALOGRAPHY; INJECTIONS, INTRAPERITONEAL; KINDLING, NEUROLOGIC; LONG-TERM CARE; MALE; PIRACETAM; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0347364700     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0013-9580.2003.34803.x     Document Type: Article

References (46)

1. Tudur SM, Marson AG, Williamson PR. Carbamazepine versus phenobarbitone monotherapy for epilepsy. Cochrane Database Syst Rev 2003;CD001:904.
2. Keck PE, McElroy SL. Carbamazepine and valproate in the maintenance treatment of bipolar disorder. J Clin Psychiatry 2002;63:13-7.
3. Post RM. Mood disorders: treatment of bipolar disorders. In: Sadock BJ, Sadock VA, eds. Comprehensive textbook of psychiatry. 7th ed. Baltimore: Lippincott Williams & Wilkins, 2000:1385-480.
4. Backonja MM. Anticonvulsants (antineuropathics) for neuropathic pain syndromes. Clin J Pain 2000;16:S67-72.
5. De Leon OA. Antiepileptic drugs for the acute and maintenance treatment of bipolar disorder. Harv Rev Psychiatry 2001;9:209-22.
6. Weiss SR, Clark M, Rosen JB, et al. Contingent tolerance to the anticonvulsant effects of carbamazepine: relationship to loss of endogenous adaptive mechanisms. Brain Res Rev 1995;20:305-25.
7. Krupp E, Heynen T, Li XL, et al. Tolerance to the anticonvulsant effects of lamotrigine on amygdala kindled seizures: cross-tolerance to carbamazepine but not valproate or diazepam. Exp Neurol 2000;162:278-89.
8. Mana MJ, Kim CK, Pinel JP, et al. Contingent tolerance to the anticonvulsant effects of carbamazepine, diazepam, and sodium valproate in kindled rats. Pharmacol Biochem Behav 1992;41:121-6.
9. Postma T, Krupp E, Li XL, et al. Lamotrigine treatment during amygdala-kindled seizure development fails to inhibit seizures and diminishes subsequent anticonvulsant efficacy. Epilepsia 2000;41:1514-21.
10. Weiss SR, Post RM, Sohn E, et al. Cross-tolerance between carbamazepine and valproate on amygdala-kindled seizures. Epilepsy Res 1993;16:37-44.
11. Zhang ZJ, Russell S, Obeng K, et al. Coadministration of gabapentin or MK-801 with lamotrigine slows tolerance to its anticonvulsant effects on kindled seizures. Pharmacol Biochem Behav 2003;74:565-71.
12. Löscher W, Honack D. Development of tolerance during chronic treatment of kindled rats with the novel antiepileptic drug levetiracetam. Epilepsia 2000;41:1499-506.
13. Labar DR. Antiepileplic drug use during the first 12 months of vagus nerve stimulation therapy: a registry study. Neurology 2002;59:S38-43.
14. Rugino TA, Samsock TC. Levetiracetam in autistic children: an open-label study. J Dev Behav Pediatr 2002;23:225-30.
15. Goldberg JF, Burdick KE. Levetiracetam for acute mania. Am J Psychiatry 2002;159:148.
16. Grunze H, Walden J. Relevance of new and newly rediscovered anticonvulsants for atypical forms of bipolar disorder. J Affect Disord 2002;72:S15-21.
17. Weiss SR, Post RM, Anthony P, et al. Contingent tolerance to carbamazepine is not affected by calcium-channel or NMDA receptor blockers. Pharmacol Biochem Behav 1993;45:439-43.
18. Kim CK, Pinel JP, Hudda MM, et al. Tolerance to the anticonvulsant effects of phenobarbital, trimethadione, and clonazepam in kindled rats: cross tolerance to carbamazepine. Pharmacol Biochem Behav 1992;41:115-20.
19. Doheny HC, Whittington MA, Jefferys JG, et al. A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsy. Br J Pharmacol 2002;135:1425-34.
20. Glien M, Brandt C, Potschka H, et al. Effects of the novel antiepileptic drug levetiracetam on spontaneous recurrent seizures in the rat pilocarpine model of temporal lobe epilepsy. Epilepsia 2002;43:350-7.
21. Gower AJ, Hirsch E, Boehrer A, et al. Effects of levetiracetam, a novel antiepileptic drug, on convulsant activity in two genetic rat models of epilepsy. Epilepsy Res 1995;22:207-13.
22. Klitgaard H, Matagne A, Gobert J, et al. Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy. Eur J Pharmacol 1998;353:191-206.
23. Löscher W, Honack D, Rundfeldt C. Antiepileptogenic effects of the novel anticonvulsant levetiracetam (ucb L059) in the kindling model of temporal lobe epilepsy. J Pharmacol Exp Ther 1998;284:474-9.
24. Lamberty Y, Margineanu DG, Klitgaard H. Effect of the new antiepileptic drug levetiracetam in an animal model of mania. Epilepsy Behav 2001;2:454-9.
25. Soderpalm B. Anticonvulsants: aspects of their mechanisms of action. Eur J Pain 2002;6(suppl A):3-9.
26. Löscher W, Honack D, Bloms-Funke P. The novel antiepileptic drug levetiracetam (ucb L059) induces alterations in GABA metabolism and turnover in discrete areas of rat brain and reduces neuronal activity in substantia nigra pars reticulata. Brain Res 1996;735:208-16.
27. Lukyanetz EA, Shkryl VM, Kostyuk PG. Selective blockade of N-type calcium channels by levetiracetam. Epilepsia 2002;43:9-18.
28. Poulain P, Margineanu DG. Levetiracetam opposes the action of GABAA antagonists in hypothalamic neurones. Neuropharmacology 2002;42:346-52.
29. Rigo JM, Hans G, Nguyen L, et al. The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents. Br J Pharmacol 2002;136:659-72.
30. Margineanu DG, Klitgaard H. Levetiracetam has no significant gamma-aminobutyric acid-related effect on paired-pulse interaction in the dentate gyrus of rats. Eur J Pharmacol 2003;466:255-61.
31. Sills GJ, Leach JP, Fraser CM, et al. Neurochemical studies with the novel anticonvulsant levetiracetam in mouse brain. Eur J Pharmacol 1997;325:35-40.
32. Tong X, Patsalos PN. A microdialysis study of the novel antiepileptic drug levetiracetam: extracellular pharmacokinetics and effect on taurine in rat brain. Br J Pharmacol 2001;133:867-74.
33. 2+ currents. Seizure 2001;10:279-86.
34. Post RM, Speer AM, Levelich GS, et al. Predictive validity of the sensitization and kindling hypothesis. In: Soares JC, Gershon S, eds. Bipolar disorders, basic mechanisms and therapeutic implications. New York: Marcel Dekker, 2000:387-432.
35. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. New York: Academic Press, 1986.
36. Racine R. Modification of seizure activity by electrical stimulation, II: motor seizure. Electroencephalogr Clin Neurophysiol 1972;32:281-94.
37. Stratton SC, Large CH, Cox B, et al. Effects of lamotrigine and levetiracetam on seizure development in a rat amygdala kindling model. Epilepsy Res 2003;53:95-106.
38. 2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists. Neuropharmacology 1999;38:1349-59.
39. Granger P, Biton B, Faure C, et al. Modulation of the gamma-aminobutyric acid type A receptor by the antiepileptic drugs carbamazepine and phenytoin. Mol Pharmacol 1995;47:1189-96.
40. Weiss SR, Post RM, Patel J, et al. Differential mediation of the anticonvulsant effects of carbamazepine and diazepam. Life Sci 1985;36:2413-9.
41. Weiss SR, Post RM. Contingent tolerance to carbamazepine: a peripheral-type benzodiazepine mechanism. Eur J Pharmacol 1991;193:159-63.
42. Silver JM, Shin C, McNamara JO. Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilepsy. Ann Neurol 1991;29:356-63.
43. Sato M, Racine RJ, McIntyre DC. Kindling: basic mechanisms and clinical validity. Electroencephalogr Clin Neurophysiol 1990;76:459-72.
44. Reddy DS, Rogawski MA. Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself. J Pharmacol Exp Ther 2000;295:1241-8.
45. Kuo CC. A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channels. Mol Pharmacol 1998;54:712-21.
46. Patsalos PN, Froscher W, Pisani F, et al. The importance of drug interactions in epilepsy therapy. Epilepsia 2002;43:365-85.