HOXC and HOXD Gene Expression in Human Endometrium: Lack of Redundancy with HOXA Paralogs

Biology of Reproduction

Volumn 70, Issue 1, 2004, Pages 39-45

  Akbas, G Eda ^a   Taylor, Hugh S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Female reproductive tract; Implantation; Menstrual cycle; M llerian ducts; Uterus

Indexed keywords

ESTRADIOL; ESTROGEN; MESSENGER RNA; PROGESTERONE; SEX HORMONE;

ADULT; ARTICLE; CELL PROLIFERATION; ENDOMETRIUM; FEMALE; GENE; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMPLANTATION; IN SITU HYBRIDIZATION; MENSTRUAL CYCLE; MUELLERIAN DUCT; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UTERUS;

ADULT; CELL LINE; DNA-BINDING PROTEINS; ENDOMETRIUM; FEMALE; GENE EXPRESSION; GONADAL STEROID HORMONES; HOMEODOMAIN PROTEINS; HUMANS; MENSTRUAL CYCLE; ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTORS; ZEBRAFISH PROTEINS;

EUKARYOTA; MAMMALIA;

EID: 0347355093     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.102.014969     Document Type: Article

References (46)

1. Hellweg GD. Histopathology of the Endometrium. New York: Springer-Verglag; 1987.
2. Noyes RW, Hertig AT, Rcok J. Dating of the endometrial biopsy. Fertil Steril 1953; 1:3-5.
3. Finn CA, Martin L. The control of implantation. J Reprod Fertil 1974; 39:195-206.
4. Navot D, Laufer N, Kopolovic J, Rabinowitz R, Birkenfeld A, Lewin A, Granat M, Margalioth EJ, Schenker JG. Artificially induced endometrial cycles and establishment of pregnancies in the absence of ovaries. N Engl J Med 1986; 314:806-811.
5. Lessey BA, Castelbaum AJU, Sawin SW, Sun J. Integrins as markers of uterine recpetivity in women with primary unexplained infertility. Fertil Steril 1995; 63:535-542.
6. Taylor HS. The role of HOX genes in human implantation. Hum Reprod Update 2000; 6:75-79.
7. McGinnis W, Krumlauf R. Homeobox genes and axial patterning. Cell 1992; 68:283-302.
8. Taylor HS. Transcriptional regulation of implantation by Hox genes. Rev Endocr Metab Disord 2002; 3:127-132.
9. Dessain S, Gross CT, Kuziora MA, McGinnis W. Antp-type homeo-domains have distinct DNA binding specificities that correlate with their different regulatory functions in embryos. EMBO J 1992; 11: 991-1002.
10. Ekker SC, Jackson DG, Vonkessler DP, Sun BI, Young KE, Beachy PA. The degree of variation in DNA-sequence recognition among 4 drosophila homeotic proteins. EMBO J 1994; 13:3551-3560.
11. Taylor HS, Vandenheuvel GB, Igarashi P. A conserved hox axis in the mouse and human female reproductive system-late establishment and persistent adult expression of the hoxa cluster genes. Biol Reprod 1997; 57:1338-1345.
12. Krumlauf R. Hox genes in vertebrate development. Cell 1994; 78: 191-201.
13. Krumlauf R. Mouse Hox genetic functions. Curr Opin Genet Dev 1993; 3:621-625.
14. Benson GV, Lim H, Paria BC, Satokata I, Dey SK, Maas RL. Mechanisms of reduced fertility in Hoxa-10 mutant mice: uterine homeosis and loss of maternal Hoxa-10 expression. Development 1996; 122: 2687-2696.
15. Satokata I, Benson G, Maas R. Sexually dimorphic sterility phenotypes in Hoxa10 deficient mice. Nature 1995; 37:460-463.
16. Hsiehli HM, Witte DP, Weinstein M, Branford W, Li H, Small K, Potter SS. Hoxa 11 structure, extensive antisense transcription, and function in male and female fertility. Development 1995; 121:1373-1385.
17. Rijli FM, Matyas R, Pellegrini M, Dierich A, Gruss P, Dolle P, Chambon P. Cryptorchidism and homeotic transformations of spinal nerves and vertebrae in Hoxa-10 mutant mice. Proc Natl Acad Sci U S A 1995; 92:8185-8189.
18. Bagot CN, Troy PJ, Taylor HS. Alteration of maternal Hoxa10 expression by in vivo gene transfection affects implantation. Gene Ther 2000; 7:1378-1384.
19. Taylor HS, Arici A, Olive D, Igarashi P. HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium. J Clin Invest 1998; 101:1379-1384.
20. Taylor HS, Igarashi P, Olive DL, Arici A. Sex steroids mediate HOXA11 expression in the human peri-implantation endometrium. J Clin Endocrinol Metab 1999; 84:1129-1135.
21. Taylor HS, Bagot C, Kardana A, Olive D, Arici A. HOX gene expression is altered in the endometrium of women with endometriosis. Hum Reprod 1999; 14:1328-1331.
22. Daftary GS, Taylor HS. Hydrosalpinx fluid diminishes endometrial cell HOXA10 expression. Fertil Steril 2002; 78:577-580.
23. Cermik D, Selam FB, Taylor HS. Regulation of HOXA10 expression by testosterone in vitro and in the endometrium of patients with PCOS. J Clin Endocrinol Metab 2003; 86:3387-3392.
24. Hostikka SL, Capecchi MR. The mouse Hoxc11 gene: genomic structure and expression pattern. Mech Dev 1998; 70:133-145.
25. Dolle P, Izpisua-Belmonte JC, Brown JM, Tickle C, Duboule D. HOX-4 genes and the morphogenesis of mammalian genitalia. Genes Dev 1991; 5:1767-1767.
26. Carpenter EM, Goddard JM, Davis AP, Nguyen TP, Capecchi MR. Targeted disruption of Hoxd-10 affects mouse hindlimb development. Dev Suppl 1997; 124:4505-4514.
27. de la Cruz CC, Der-Avakian A, Spyropoulos DD, Tieu DD, Carpenter EM. Targeted disruption of Hoxd9 and Hoxd10 alters locomotor behavior, vertebral identity, and peripheral nervous system development. Dev Biol 1999; 216:595-610.
28. Redline RW, Hudock P, MacFee M, Patterson P. Expression of AbdB-type homeobox genes in human tumors. Lab Invest 1994; 71:663-670.
29. Favier B, Le Meur M, Chambon P, Dolle P. Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice. Proc Natl Acad Sci U S A 1995; 92:310-314.
30. Davis AP, Capecchi MR. Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11. Dev Suppl 1994; 120:2187-2198.
31. Small KM, Potter SS. Homeotic transformations and limb defects in Hox A11 mutant mice. Genes Dev 1993; 7:2318-2328.
32. Patterson LT, Pembaur M, Potter SS. Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney. Development 2001; 128:2153-2161.
33. Casey ML, Smith JW, Nagai K, Hersh LB, MacDonald PC. Progesterone-regulated cyclic modulation of membrane metalloendopeptidase (enkephalinase) in human endometrium. J Biol Chem 1991; 266: 23041-23047.
34. Apostolakos MJ, Schuermann WH, Frampton MW, Utell MJ, Willey JC. Measurement of gene expression by multiplex competitive polymerase chain reaction. Anal Biochem 1993; 213:277-284.
35. de Stanchina E, Gabellini D, Norio P, Giacca M, Peverali FA, Riva S, Falaschi A, Biamonti G. Selection of homeotic proteins for binding to a human DNA replication origin. J Mol Biol 2000; 299:667-680.
36. Donaldson AD, Blow JJ. The regulation of replication origin activation. Curr Opin Genet Dev 1999; 9:62-68.
37. Kumar S, Giacca M, Norio P, Biamonti G, Riva S, Falaschi A. Utilization of the same DNA replication origin by human cells of different derivation. Nucleic Acids Res 1996; 24:3289-3294.
38. Gabellini D, Colaluca IN, Vodermaier HC, Biamonti G, Giacca M, Falaschi A, Riva S, Perverali FA. Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression. EMBO J. 2003; 22:3715-3724.
39. Troy PJ, Daftary GS, Taylor HS. Transcriptional repression of peri-implantation EMX2 expression in mamallian reproduction by HOXA10. Mol Cell Biol 2003; 23:1-13.
40. Goff DJ, Tabin CJ. Analysis of Hoxd-13 and Hoxd-11 misexpression in chick limb buds reveals that Hox genes affect both bone condensation and growth. Development 1997; 124:627-636.
41. Davis AP, Witte DP, Hsieh-Li HM, Potter SS, Capecchi MR. Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11. Nature 1995; 375:791-795.
42. Horan GS, Ramirez-Solis R, Featherstone MS, Wolgemuth DJ, Bradley A, Behringer RR. Compound mutants for the paralogous hoxa-4, hoxb-4, and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed. Genes Dev 1995; 9:1667-1677.
43. Zakany J, Fromental-Ramain C, Warot X, Duboule D. Regulation of number and size of digits by posterior Hox genes: a dose-dependent mechanism with potential evolutionary implications. Proc Natl Acad Sci U S A 1997; 94:13695-13700.
44. Studer M, Gavalas A, Marshall H, Ariza-McNaughton L, Rijli FM, Chambon P, Krumlauf R. Genetic interactions between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning. Development 1998; 125:1025-1036.
45. Chen F, Capecchi MR. Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy. Proc Natl Acad Sci U S A 1999; 96: 541-546.
46. Rossel M, Capecchi MR. Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development 1999; 126:5027-5040.