메뉴 건너뛰기




Volumn 57, Issue 1, 2004, Pages 27-36

Vasopeptidase inhibitors: Will they have a role in clinical practice?

Author keywords

ACE inhibitors; Natriuretic peptides; Vasopeptidase inhibitors

Indexed keywords

7 (2 ACETYLTHIO 3 PHENYLPROPIONAMIDO) 1,2,3,4,6,7,8,12B OCTAHYDRO 6 OXOPYRIDO[2,1 A][2]BENZAZEPINE 4 CARBOXYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BRAIN NATRIURETIC PEPTIDE; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; FASIDOTRIL; GEMOPATRILAT; LISINOPRIL; MEMBRANE METALLOENDOPEPTIDASE; METALLOPROTEINASE INHIBITOR; MIXANPRIL; N (2 MERCAPTOMETHYL 3 PHENYLPROPIONYL) BETA ALANINE; NEUROHORMONE; OMAPATRILAT; SAMIPATRILAT; UNCLASSIFIED DRUG; VASOPEPTIDASE INHIBITOR; Z 13752 A;

EID: 0347319047     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2003.01947.x     Document Type: Review
Times cited : (35)

References (105)
  • 1
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
    • The Heart Outcomes Prevention Evaluation Study Investigators
    • Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342: 145-53.
    • (2000) N Engl J Med , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3    Bosch, J.4    Davies, R.5    Dagenais, G.6
  • 2
    • 0026786643 scopus 로고
    • Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial
    • The SAVE Investigators
    • Pfeffer MA, Braunwald E, Moye LA, Basta L, Brown EJ Jr, Cuddy TE, Davis BR, Geltman EM, Goldman S, Flaker GC, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med 1992; 327: 669-77.
    • (1992) N Engl J Med , vol.327 , pp. 669-677
    • Pfeffer, M.A.1    Braunwald, E.2    Moye, L.A.3    Basta, L.4    Brown Jr., E.J.5    Cuddy, T.E.6    Davis, B.R.7    Geltman, E.M.8    Goldman, S.9    Flaker, G.C.10
  • 3
    • 0027423378 scopus 로고
    • Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure
    • The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators
    • Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators. Lancet 1993; 342: 821-8.
    • (1993) Lancet , vol.342 , pp. 821-828
  • 4
    • 9044239676 scopus 로고
    • A clinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction
    • Trandolapril Cardiac Evaluation (TRACE) Study Group
    • Kober L, Torp-Pedersen C, Carlsen JE, Bagger H, Eliasen P, Lyngborg K, Videbaek J, Cole DS, Auclert L, Pauly NC. A clinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. Trandolapril Cardiac Evaluation (TRACE) Study Group. N Engl J Med 1995; 333: 1670-6.
    • (1995) N Engl J Med , vol.333 , pp. 1670-1676
    • Kober, L.1    Torp-Pedersen, C.2    Carlsen, J.E.3    Bagger, H.4    Eliasen, P.5    Lyngborg, K.6    Videbaek, J.7    Cole, D.S.8    Auclert, L.9    Pauly, N.C.10
  • 5
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
    • The SOLVD Investigators
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD Investigators. N Engl J Med 1991; 325: 293-302.
    • (1991) N Engl J Med , vol.325 , pp. 293-302
  • 6
    • 0023266532 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS)
    • The CONSENSUS Trial Study Group
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). The CONSENSUS Trial Study Group. N Engl J Med 1987; 316: 1429-35.
    • (1987) N Engl J Med , vol.316 , pp. 1429-1435
  • 7
    • 0033030241 scopus 로고    scopus 로고
    • Kinin-mediated coronary nitric oxide production contributes to the therapeutic action of angiotensin-converting enzyme and neutral endopeptidase inhibitors and amlodipine in the treatment in heart failure
    • Zhang X, Recchia FA, Bernstein R, Xu X, Nasjletti A, Hintze TH. Kinin-mediated coronary nitric oxide production contributes to the therapeutic action of angiotensin-converting enzyme and neutral endopeptidase inhibitors and amlodipine in the treatment in heart failure. J Pharmacol Exp Ther 1999; 288: 742-51.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 742-751
    • Zhang, X.1    Recchia, F.A.2    Bernstein, R.3    Xu, X.4    Nasjletti, A.5    Hintze, T.H.6
  • 8
    • 0006862091 scopus 로고    scopus 로고
    • Role of bradykinin in mediating vascular effects of angiotensin- converting enzyme inhibitors in humans
    • Hornig B, Kohler C, Drexler H. Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors in humans. Circulation 1997; 95: 1115-18.
    • (1997) Circulation , vol.95 , pp. 1115-1118
    • Hornig, B.1    Kohler, C.2    Drexler, H.3
  • 9
    • 0017578611 scopus 로고
    • Design of specific inhibitors of angiotensin-converting enzyme: New class of orally active antihypertensive agents
    • Ondetti MA, Rubin B, Cushman DW. Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents. Science 1977; 196: 441-4.
    • (1977) Science , vol.196 , pp. 441-444
    • Ondetti, M.A.1    Rubin, B.2    Cushman, D.W.3
  • 11
  • 12
    • 0022981549 scopus 로고
    • The renal response to neuroendocrine inhibition in chronic heart failure, double-blind comparison of captopril and prazosin
    • Bayliss J, Canepa-Anson R, Norell M, Poole-Wilson P, Sutton G. The renal response to neuroendocrine inhibition in chronic heart failure, double-blind comparison of captopril and prazosin. Eur Heart J 1986; 7: 877-84.
    • (1986) Eur Heart J , vol.7 , pp. 877-884
    • Bayliss, J.1    Canepa-Anson, R.2    Norell, M.3    Poole-Wilson, P.4    Sutton, G.5
  • 13
    • 34447331122 scopus 로고
    • Electronmicroscopy of the atrium of the heart
    • Kisch B. Electronmicroscopy of the atrium of the heart. Exp Med Surg 1956; 14: 99-132.
    • (1956) Exp Med Surg , vol.14 , pp. 99-132
    • Kisch, B.1
  • 14
    • 0019352579 scopus 로고
    • A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats
    • de Bold AJ, Borenstein HB, Veress AT, Sonnenberg H. A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats. Life Sci 1981; 28: 89-94.
    • (1981) Life Sci , vol.28 , pp. 89-94
    • De Bold, A.J.1    Borenstein, H.B.2    Veress, A.T.3    Sonnenberg, H.4
  • 15
    • 0021281702 scopus 로고
    • Purification and complete amino acid sequence of beta-rat atrial natriuretic polypeptide (beta-rANP) of 5,000 daltons
    • Kangawa K, Fukuda A, Minamino N, Matsuo H. Purification and complete amino acid sequence of beta-rat atrial natriuretic polypeptide (beta-rANP) of 5,000 daltons. Biochem Biophys Res Commun 1984; 119: 933-40.
    • (1984) Biochem Biophys Res Commun , vol.119 , pp. 933-940
    • Kangawa, K.1    Fukuda, A.2    Minamino, N.3    Matsuo, H.4
  • 16
    • 0030217898 scopus 로고    scopus 로고
    • Two cardiac natriuretic peptide genes (atrial natriuretic peptide and brain natriuretic peptide) are organized in tandem in the mouse and human genomes
    • Tamura N, Ogawa Y, Yasoda A, Itoh H, Saito Y, Nakao K. Two cardiac natriuretic peptide genes (atrial natriuretic peptide and brain natriuretic peptide) are organized in tandem in the mouse and human genomes. J Mol Cell Cardiol 1996; 28: 1811-15.
    • (1996) J Mol Cell Cardiol , vol.28 , pp. 1811-1815
    • Tamura, N.1    Ogawa, Y.2    Yasoda, A.3    Itoh, H.4    Saito, Y.5    Nakao, K.6
  • 17
    • 0026703056 scopus 로고
    • Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of 'vascular natriuretic peptide system'
    • Suga S, Nakao K, Itoh H, Komatsu Y, Ogawa Y, Hama N, Imura H. Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of 'vascular natriuretic peptide system'. J Clin Invest 1992; 90: 1145-9.
    • (1992) J Clin Invest , vol.90 , pp. 1145-1149
    • Suga, S.1    Nakao, K.2    Itoh, H.3    Komatsu, Y.4    Ogawa, Y.5    Hama, N.6    Imura, H.7
  • 19
    • 0025312570 scopus 로고
    • C-type natriuretic peptide (CNP): A new member of natriuretic peptide family identified in porcine brain
    • Sudoh T, Minamino N, Kangawa K, Matsuo H. C-type natriuretic peptide (CNP): a new member of natriuretic peptide family identified in porcine brain. Biochem Biophys Res Commun 1990; 168: 863-70.
    • (1990) Biochem Biophys Res Commun , vol.168 , pp. 863-870
    • Sudoh, T.1    Minamino, N.2    Kangawa, K.3    Matsuo, H.4
  • 20
    • 0028578107 scopus 로고
    • Molecular cloning and chromosomal assignment of the mouse C-type natriuretic peptide (CNP) gene (Nppc): Comparison with the human CNP gene (NPPC)
    • Ogawa Y, Itoh H, Yoshitake Y, Inoue M, Yoshimasa T, Serikawa T, Nakao K. Molecular cloning and chromosomal assignment of the mouse C-type natriuretic peptide (CNP) gene (Nppc): comparison with the human CNP gene (NPPC). Genomics 1994; 24: 383-7.
    • (1994) Genomics , vol.24 , pp. 383-387
    • Ogawa, Y.1    Itoh, H.2    Yoshitake, Y.3    Inoue, M.4    Yoshimasa, T.5    Serikawa, T.6    Nakao, K.7
  • 22
    • 0024364093 scopus 로고
    • Antihypertensive effect of a 5-day infusion of atrial natriuretic factor in humans
    • Janssen WM, de Zeeuw D, van der Hem GK, de Jong PE. Antihypertensive effect of a 5-day infusion of atrial natriuretic factor in humans. Hypertension 1989; 13: 640-6.
    • (1989) Hypertension , vol.13 , pp. 640-646
    • Janssen, W.M.1    De Zeeuw, D.2    Van Der Hem, G.K.3    De Jong, P.E.4
  • 24
    • 0029935496 scopus 로고    scopus 로고
    • C-type natriuretic peptide. An endogenous inhibitor of vascular angiotensin-converting enzyme activity
    • Davidson NC, Barr CS, Struthers AD. C-type natriuretic peptide. An endogenous inhibitor of vascular angiotensin-converting enzyme activity. Circulation 1996; 93: 1155-9.
    • (1996) Circulation , vol.93 , pp. 1155-1159
    • Davidson, N.C.1    Barr, C.S.2    Struthers, A.D.3
  • 25
    • 0024849397 scopus 로고
    • Interaction between atrial natriuretic peptide and the renin angiotensin aldosterone system. Endogenous antagonists
    • Johnston CI, Hodsman PG, Kohzuki M, Casley DJ, Fabris B, Phillips PA. Interaction between atrial natriuretic peptide and the renin angiotensin aldosterone system. Endogenous antagonists. Am J Med 1989; 87: 24S-28S.
    • (1989) Am J Med , vol.87
    • Johnston, C.I.1    Hodsman, P.G.2    Kohzuki, M.3    Casley, D.J.4    Fabris, B.5    Phillips, P.A.6
  • 26
    • 0037028862 scopus 로고    scopus 로고
    • Gradual reactivation over time of vascular tissue angiotensin I to angiotensin II conversion during chronic lisinopril therapy in chronic heart failure
    • Farquharson CA, Struthers AD. Gradual reactivation over time of vascular tissue angiotensin I to angiotensin II conversion during chronic lisinopril therapy in chronic heart failure. J Am Coll Cardiol 2002; 39: 767-75.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 767-775
    • Farquharson, C.A.1    Struthers, A.D.2
  • 27
    • 0023874660 scopus 로고
    • Atrial stretch, not pressure, is the principal determinant controlling the acute release of atrial natriuretic factor
    • Edwards BS, Zimmerman RS, Schwab TR, Heublein DM, Burnett JC Jr. Atrial stretch, not pressure, is the principal determinant controlling the acute release of atrial natriuretic factor. Circ Res 1988; 62: 191-5.
    • (1988) Circ Res , vol.62 , pp. 191-195
    • Edwards, B.S.1    Zimmerman, R.S.2    Schwab, T.R.3    Heublein, D.M.4    Burnett Jr., J.C.5
  • 28
    • 0021889298 scopus 로고
    • Atrial natriuretic factor - A circulating hormone stimulated by Volume loading
    • Lang RE, Tholken H, Ganten D, Luft FC, Ruskoaho H, Unger T. Atrial natriuretic factor - a circulating hormone stimulated by Volume loading. Nature 1985; 314: 264-6.
    • (1985) Nature , vol.314 , pp. 264-266
    • Lang, R.E.1    Tholken, H.2    Ganten, D.3    Luft, F.C.4    Ruskoaho, H.5    Unger, T.6
  • 29
    • 0027014358 scopus 로고
    • Atrial natriuretic peptide, synthesis, release, and metabolism
    • Ruskoaho H. Atrial natriuretic peptide, synthesis, release, and metabolism. Pharmacol Rev 1992; 44: 479-602.
    • (1992) Pharmacol Rev , vol.44 , pp. 479-602
    • Ruskoaho, H.1
  • 32
    • 0037181511 scopus 로고    scopus 로고
    • Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: A randomized controlled trial
    • Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial. JAMA 2002; 287: 1531-40.
    • (2002) JAMA , vol.287 , pp. 1531-1540
  • 34
    • 0028905582 scopus 로고
    • The role of neutral endopeptidase in dogs with evolving congestive heart failure
    • Margulies KB, Barclay PL, Burnett JC Jr. The role of neutral endopeptidase in dogs with evolving congestive heart failure. Circulation 1995; 91: 2036-42.
    • (1995) Circulation , vol.91 , pp. 2036-2042
    • Margulies, K.B.1    Barclay, P.L.2    Burnett Jr., J.C.3
  • 35
    • 0029119718 scopus 로고
    • Regulation and differential expression of neutral endopeptidase 24.11 in human endothelial cells
    • Graf K, Koehne P, Grafe M, Zhang M, Auch-Schwelk W, Fleck E. Regulation and differential expression of neutral endopeptidase 24.11 in human endothelial cells. Hypertension 1995; 26: 230-5.
    • (1995) Hypertension , vol.26 , pp. 230-235
    • Graf, K.1    Koehne, P.2    Grafe, M.3    Zhang, M.4    Auch-Schwelk, W.5    Fleck, E.6
  • 36
    • 0024538318 scopus 로고
    • Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones
    • Erdos EG, Skidgel RA. Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones. Faseb J 1989; 3: 145-51.
    • (1989) Faseb J , vol.3 , pp. 145-151
    • Erdos, E.G.1    Skidgel, R.A.2
  • 37
    • 0027526508 scopus 로고
    • Characterization of neutral endopeptidase in vascular smooth muscle cells of rabbit renal cortex
    • Dussaule JC, Stefanski A, Bea ML, Ronco P, Ardaillou R. Characterization of neutral endopeptidase in vascular smooth muscle cells of rabbit renal cortex. Am J Physiol 1993; 264: F45-F52.
    • (1993) Am J Physiol , vol.264
    • Dussaule, J.C.1    Stefanski, A.2    Bea, M.L.3    Ronco, P.4    Ardaillou, R.5
  • 38
    • 0023101641 scopus 로고
    • The hydrolysis of alpha-human atrial natriuretic peptide by pig kidney microvillar membranes is initiated by endopeptidase-24.11
    • Stephenson SL, Kenny AJ. The hydrolysis of alpha-human atrial natriuretic peptide by pig kidney microvillar membranes is initiated by endopeptidase-24.11. Biochem J 1987; 243: 183-7.
    • (1987) Biochem J , vol.243 , pp. 183-187
    • Stephenson, S.L.1    Kenny, A.J.2
  • 39
    • 0026663368 scopus 로고
    • Clearance of brain natriuretic peptide in patients with chronic heart failure: Indirect evidence for a neutral endopeptidase mechanism but against an atrial natriuretic peptide clearance receptor mechanism
    • Lond
    • Lang CC, Motwani JG, Coutie WJ, Struthers AD. Clearance of brain natriuretic peptide in patients with chronic heart failure: indirect evidence for a neutral endopeptidase mechanism but against an atrial natriuretic peptide clearance receptor mechanism. Clin Sci (Lond) 1992; 82: 619-23.
    • (1992) Clin Sci , vol.82 , pp. 619-623
    • Lang, C.C.1    Motwani, J.G.2    Coutie, W.J.3    Struthers, A.D.4
  • 40
    • 0027457459 scopus 로고
    • Hydrolysis of human and pig brain natriuretic peptides, urodilatin, C-type natriuretic peptide and some C-receptor ligands by endopeptidase-24.11
    • Kenny AJ, Bourne A, Ingram J. Hydrolysis of human and pig brain natriuretic peptides, urodilatin, C-type natriuretic peptide and some C-receptor ligands by endopeptidase-24.11. Biochem J 1993; 291 (1): 83-8.
    • (1993) Biochem J , vol.291 , Issue.1 , pp. 83-88
    • Kenny, A.J.1    Bourne, A.2    Ingram, J.3
  • 41
    • 0021175531 scopus 로고
    • Hydrolysis of substance, p. & neurotensin by converting enzyme and neutral endopeptidase
    • Skidgel RA, Engelbrecht S, Johnson AR, Erdos EG. Hydrolysis of substance, p. & neurotensin by converting enzyme and neutral endopeptidase. Peptides 1984; 5: 769-76.
    • (1984) Peptides , vol.5 , pp. 769-776
    • Skidgel, R.A.1    Engelbrecht, S.2    Johnson, A.R.3    Erdos, E.G.4
  • 42
    • 0027963329 scopus 로고
    • Generation by the phosphoramidon-sensitive peptidases, endopeptidase-24.11 and thermolysin, of endothelin-1 and c-terminal fragment from big endothelin-1
    • Murphy LJ, Corder R, Mallet AI, Turner AJ. Generation by the phosphoramidon-sensitive peptidases, endopeptidase-24.11 and thermolysin, of endothelin-1 and c-terminal fragment from big endothelin-1. Br J Pharmacol 1994; 113: 137-42.
    • (1994) Br J Pharmacol , vol.113 , pp. 137-142
    • Murphy, L.J.1    Corder, R.2    Mallet, A.I.3    Turner, A.J.4
  • 43
    • 0032537519 scopus 로고    scopus 로고
    • Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo
    • Ferro CJ, Spratt JC, Haynes WG, Webb DJ. Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo. Circulation 1998; 97: 2323-30.
    • (1998) Circulation , vol.97 , pp. 2323-2330
    • Ferro, C.J.1    Spratt, J.C.2    Haynes, W.G.3    Webb, D.J.4
  • 45
    • 0024322626 scopus 로고
    • Protection of atrial natriuretic factor against degradation, diuretic and natriuretic responses after in vivo inhibition of enkephalinase (EC 3.4.24.11) by acetorphan
    • Gros C, Souque A, Schwartz JC, Duchier J, Cournot A, Baumer P, Lecomte JM. Protection of atrial natriuretic factor against degradation, diuretic and natriuretic responses after in vivo inhibition of enkephalinase (EC 3.4.24.11) by acetorphan. Proc Natl Acad Sci USA 1989; 86: 7580-4.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7580-7584
    • Gros, C.1    Souque, A.2    Schwartz, J.C.3    Duchier, J.4    Cournot, A.5    Baumer, P.6    Lecomte, J.M.7
  • 46
    • 0025009278 scopus 로고
    • Enkephalinase (EC 3.4.24.11) inhibitors: Protection of endogenous ANF against inactivation and potential therapeutic applications
    • Schwartz JC, Gros C, Lecomte JM, Bralet J. Enkephalinase (EC 3.4.24.11) inhibitors: protection of endogenous ANF against inactivation and potential therapeutic applications. Life Sci 1990; 47: 1279-97.
    • (1990) Life Sci , vol.47 , pp. 1279-1297
    • Schwartz, J.C.1    Gros, C.2    Lecomte, J.M.3    Bralet, J.4
  • 48
    • 0025832395 scopus 로고
    • Prolonged inhibition of endopeptidase 24.11 in normal man: Renal, endocrine and haemodynamic effects
    • Richards AM, Wittert G, Espiner EA, Yandle TG, Frampton C, Ikram H. Prolonged inhibition of endopeptidase 24.11 in normal man: renal, endocrine and haemodynamic effects. J Hypertens 1991; 9: 955-62.
    • (1991) J Hypertens , vol.9 , pp. 955-962
    • Richards, A.M.1    Wittert, G.2    Espiner, E.A.3    Yandle, T.G.4    Frampton, C.5    Ikram, H.6
  • 49
    • 0027216490 scopus 로고
    • Renal and hormonal effects of chronic inhibition of neutral endopeptidase (EC 3.4.24.11) in normal man
    • Lond
    • O'Connell JE, Jardine AG, Davies DL, McQueen J, Connell JM. Renal and hormonal effects of chronic inhibition of neutral endopeptidase (EC 3.4.24.11) in normal man. Clin Sci (Lond) 1993; 85: 19-26.
    • (1993) Clin Sci , vol.85 , pp. 19-26
    • O'Connell, J.E.1    Jardine, A.G.2    Davies, D.L.3    McQueen, J.4    Connell, J.M.5
  • 51
    • 0028856125 scopus 로고
    • Comparison of candoxatril and atrial natriuretic factor in healthy men. Effects on hemodynamics, sympathetic activity, heart rate variability, and endothelin
    • Ando S, Rahman MA, Butler GC, Senn BL, Floras JS. Comparison of candoxatril and atrial natriuretic factor in healthy men. Effects on hemodynamics, sympathetic activity, heart rate variability, and endothelin. Hypertension 1995; 26: 1160-6.
    • (1995) Hypertension , vol.26 , pp. 1160-1166
    • Ando, S.1    Rahman, M.A.2    Butler, G.C.3    Senn, B.L.4    Floras, J.S.5
  • 53
    • 0028114340 scopus 로고
    • Antihypertensive effects of the neutral endopeptidase inhibitor SCH 42495 in essential hypertension
    • Ogihara T, Rakugi H, Masuo K, Yu H, Nagano M, Mikami H. Antihypertensive effects of the neutral endopeptidase inhibitor SCH 42495 in essential hypertension. Am J Hypertens 1994; 7: 943-7.
    • (1994) Am J Hypertens , vol.7 , pp. 943-947
    • Ogihara, T.1    Rakugi, H.2    Masuo, K.3    Yu, H.4    Nagano, M.5    Mikami, H.6
  • 54
    • 0029033215 scopus 로고
    • Pharmacokinetic-pharmacodynamic (PK-PD) modeling for a new antihypertensive agent (neutral metalloendopeptidase inhibitor SCH 42354) in patients with mild to moderate hypertension
    • Fettner SH, Pai S, Zhu GR, Kosoglou T, Banfield CR, Batra V. Pharmacokinetic-pharmacodynamic (PK-PD) modeling for a new antihypertensive agent (neutral metalloendopeptidase inhibitor SCH 42354) in patients with mild to moderate hypertension. Eur J Clin Pharmacol 1995; 48: 351-9.
    • (1995) Eur J Clin Pharmacol , vol.48 , pp. 351-359
    • Fettner, S.H.1    Pai, S.2    Zhu, G.R.3    Kosoglou, T.4    Banfield, C.R.5    Batra, V.6
  • 56
    • 0027173606 scopus 로고
    • Chronic inhibition of endopeptidase 24.11 in essential hypertension: Evidence for enhanced atrial natriuretic peptide and angiotensin II
    • Richards AM, Wittert GA, Crozier IG, Espiner EA, Yandle TG, Ikram H, Frampton C. Chronic inhibition of endopeptidase 24.11 in essential hypertension: evidence for enhanced atrial natriuretic peptide and angiotensin II. J Hypertens 1993; 11: 407-16.
    • (1993) J Hypertens , vol.11 , pp. 407-416
    • Richards, A.M.1    Wittert, G.A.2    Crozier, I.G.3    Espiner, E.A.4    Yandle, T.G.5    Ikram, H.6    Frampton, C.7
  • 59
    • 0033064444 scopus 로고    scopus 로고
    • Fosinopril reduces left ventricular mass in untreated hypertensive patients: A controlled trial
    • Cheung BM, Lau CP. Fosinopril reduces left ventricular mass in untreated hypertensive patients: a controlled trial. Br J Clin Pharmacol 1999; 47: 179-87.
    • (1999) Br J Clin Pharmacol , vol.47 , pp. 179-187
    • Cheung, B.M.1    Lau, C.P.2
  • 62
    • 0028273258 scopus 로고
    • GISSI-3. Effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction
    • Gruppo Italiano per lo Studio della Sopravvivenza nell'infarto Miocardico
    • GISSI-3. effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction. Gruppo Italiano per lo Studio della Sopravvivenza nell'infarto Miocardico. Lancet 1994; 343: 1115-22.
    • (1994) Lancet , vol.343 , pp. 1115-1122
  • 63
    • 0028816282 scopus 로고
    • The effect of the angiotensin-converting-enzyme inhibitor zofenopril on mortality and morbidity after anterior myocardial infarction. The Survival of Myocardial Infarction Long-Term Evaluation (SMILE) Study Investigators
    • Ambrosioni E, Borghi C, Magnani B. The effect of the angiotensin- converting-enzyme inhibitor zofenopril on mortality and morbidity after anterior myocardial infarction. The Survival of Myocardial Infarction Long-Term Evaluation (SMILE) Study Investigators. N Engl J Med 1995; 332: 80-5.
    • (1995) N Engl J Med , vol.332 , pp. 80-85
    • Ambrosioni, E.1    Borghi, C.2    Magnani, B.3
  • 64
    • 0031954807 scopus 로고    scopus 로고
    • Neutral endopeptidase and angiotensin-converting enzyme inhibitors increase nitric oxide production in isolated canine coronary microvessels by a kinin-dependent mechanism
    • Zhang X, Nasjletti A, Xu X, Hintze TH. Neutral endopeptidase and angiotensin-converting enzyme inhibitors increase nitric oxide production in isolated canine coronary microvessels by a kinin-dependent mechanism. J Cardiovasc Pharmacol 1998; 31: 623-9.
    • (1998) J Cardiovasc Pharmacol , vol.31 , pp. 623-629
    • Zhang, X.1    Nasjletti, A.2    Xu, X.3    Hintze, T.H.4
  • 65
    • 0035083665 scopus 로고    scopus 로고
    • Comparison of a vasopeptidase inhibitor with neutral endopeptidase and angiotensin-converting enzyme inhibitors on bradykinin metabolism in the rat coronary bed
    • Dumoulin MJ, Adam A, Rouleau JL, Lamontagne D. Comparison of a vasopeptidase inhibitor with neutral endopeptidase and angiotensin-converting enzyme inhibitors on bradykinin metabolism in the rat coronary bed. J Cardiovasc Pharmacol 2001; 37: 359-66.
    • (2001) J Cardiovasc Pharmacol , vol.37 , pp. 359-366
    • Dumoulin, M.J.1    Adam, A.2    Rouleau, J.L.3    Lamontagne, D.4
  • 66
    • 0029742344 scopus 로고    scopus 로고
    • Mercaptoacyl dipeptides a s orally active dual inhibitors of angiotensin-converting enzyme and neutral endopeptidase
    • Fink CA, Carlson JE, McTaggart PA, Qiao Y, Webb R, Chatelain R, Jeng AY, Trapani AJ. Mercaptoacyl dipeptides a s orally active dual inhibitors of angiotensin-converting enzyme and neutral endopeptidase. J Med Chem 1996; 39: 3158-68.
    • (1996) J Med Chem , vol.39 , pp. 3158-3168
    • Fink, C.A.1    Carlson, J.E.2    McTaggart, P.A.3    Qiao, Y.4    Webb, R.5    Chatelain, R.6    Jeng, A.Y.7    Trapani, A.J.8
  • 67
    • 0029619616 scopus 로고
    • Cardiovascular effects of the novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme BMS-182657 in experimental hypertension and heart failure
    • Trippodo NC, Robl JA, Asaad MM, Bird JE, Panchal BC, Schaeffer TR, Fox M, Giancarli MR, Cheung HS. Cardiovascular effects of the novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme BMS-182657 in experimental hypertension and heart failure. J Pharmacol Exp Ther 1995; 275: 745-52.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 745-752
    • Trippodo, N.C.1    Robl, J.A.2    Asaad, M.M.3    Bird, J.E.4    Panchal, B.C.5    Schaeffer, T.R.6    Fox, M.7    Giancarli, M.R.8    Cheung, H.S.9
  • 68
    • 0029971125 scopus 로고    scopus 로고
    • Design of orally active dual inhibitors of neutral endopeptidase and angiotensin-converting enzyme with long duration of action
    • Fournie-Zaluski MC, Coric P, Thery V, Gonzalez W, Meudal H, Turcaud S, Michel JB, Roques BP. Design of orally active dual inhibitors of neutral endopeptidase and angiotensin-converting enzyme with long duration of action. J Med Chem 1996; 39: 2594-608.
    • (1996) J Med Chem , vol.39 , pp. 2594-2608
    • Fournie-Zaluski, M.C.1    Coric, P.2    Thery, V.3    Gonzalez, W.4    Meudal, H.5    Turcaud, S.6    Michel, J.B.7    Roques, B.P.8
  • 69
    • 0030439235 scopus 로고    scopus 로고
    • Inhibition of both angiotensin-converting enzyme and neutral endopeptidase by S21402 (RB105) in rats with experimental myocardial infarction
    • Gonzalez W, Beslot F, Laboulandine I, Fournie-Zaluski MC, Roques BP, Michel JB. Inhibition of both angiotensin-converting enzyme and neutral endopeptidase by S21402 (RB105) in rats with experimental myocardial infarction. J Pharmacol Exp Ther 1996; 278: 573-81.
    • (1996) J Pharmacol Exp Ther , vol.278 , pp. 573-581
    • Gonzalez, W.1    Beslot, F.2    Laboulandine, I.3    Fournie-Zaluski, M.C.4    Roques, B.P.5    Michel, J.B.6
  • 72
    • 0028819075 scopus 로고
    • Repression of angiotensin II and potentiation of bradykinin contribute to the synergistic effects of dual metalloprotease inhibition in heart failure
    • Trippodo NC, Panchal BC, Fox M. Repression of angiotensin II and potentiation of bradykinin contribute to the synergistic effects of dual metalloprotease inhibition in heart failure. J Pharmacol Exp Ther 1995; 272: 619-27.
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 619-627
    • Trippodo, N.C.1    Panchal, B.C.2    Fox, M.3
  • 73
    • 0035148538 scopus 로고    scopus 로고
    • Vasopeptidase Inhibition Prevents Endothelial Dysfunction of Resistance Arteries in Salt-Sensitive Hypertension in Comparison with Single ACE Inhibition
    • d'Uscio LV, Quaschning T, Burnett JC Jr, Luscher TF. Vasopeptidase Inhibition Prevents Endothelial Dysfunction of Resistance Arteries in Salt-Sensitive Hypertension in Comparison With Single ACE Inhibition. Hypertension 2001; 37: 28-33.
    • (2001) Hypertension , vol.37 , pp. 28-33
    • D'Uscio, L.V.1    Quaschning, T.2    Burnett Jr., J.C.3    Luscher, T.F.4
  • 74
    • 0037173041 scopus 로고    scopus 로고
    • Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertension: Results of the conduit hemodynamics of omapatrilat international research study
    • Mitchell GF, Izzo JL Jr, Lacourciere Y, Ouellet JP, Neutel J, Qian C, Kerwin LJ, Block AJ, Pfeffer MA. Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertension: results of the conduit hemodynamics of omapatrilat international research study. Circulation 2002; 105: 2955-61.
    • (2002) Circulation , vol.105 , pp. 2955-2961
    • Mitchell, G.F.1    Izzo Jr., J.L.2    Lacourciere, Y.3    Ouellet, J.P.4    Neutel, J.5    Qian, C.6    Kerwin, L.J.7    Block, A.J.8    Pfeffer, M.A.9
  • 75
    • 0025973972 scopus 로고
    • Antihypertensive activity during inhibition of neutral endopeptidase and angiotensin converting enzyme
    • Seymour AA, Swerdel JN, Abboa-Offei B. Antihypertensive activity during inhibition of neutral endopeptidase and angiotensin converting enzyme. J Cardiovasc Pharmacol 1991; 17: 456-65.
    • (1991) J Cardiovasc Pharmacol , vol.17 , pp. 456-465
    • Seymour, A.A.1    Swerdel, J.N.2    Abboa-Offei, B.3
  • 76
    • 0028838979 scopus 로고
    • Hypotensive and natriuretic effects of RB 105, a new dual inhibitor of angiotensin converting enzyme and neutral endopeptidase in hypertensive rats
    • Gonzalez Vera W, Fournie-Zaluski MC, Pham I, Laboulandine I, Roques BP, Michel JB. Hypotensive and natriuretic effects of RB 105, a new dual inhibitor of angiotensin converting enzyme and neutral endopeptidase in hypertensive rats. J Pharmacol Exp Ther 1995; 272: 343-51.
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 343-351
    • Gonzalez Vera, W.1    Fournie-Zaluski, M.C.2    Pham, I.3    Laboulandine, I.4    Roques, B.P.5    Michel, J.B.6
  • 77
    • 0000326308 scopus 로고    scopus 로고
    • Supine mean arterial blood pressure (MAP) lowering and oral tolerance of BMS-186716, a new dual metalloprotease inhibitor of angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP), in healthy male subjects
    • Liao W, Delaney C, Smith P. Supine mean arterial blood pressure (MAP) lowering and oral tolerance of BMS-186716, a new dual metalloprotease inhibitor of angiotensin converting enzyme (ACE) and neutral endopeptidase (NEP), in healthy male subjects (Abstract). Clin Pharmacol Ther 1997; 61: 229.
    • (1997) Clin Pharmacol Ther , vol.61 , pp. 229
    • Liao, W.1    Delaney, C.2    Smith, P.3
  • 78
    • 0001643315 scopus 로고    scopus 로고
    • Effects ode BMS-186716, a new dual metalloprotease inhibitor, on pharmacodynamic markers of neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE) activity in healthy men
    • Vesterqvist O, Liao W, Manning JA. Effects ode BMS-186716, a new dual metalloprotease inhibitor, on pharmacodynamic markers of neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE) activity in healthy men (Abstract). Clin Pharmacol Ther 1997; 61: 230.
    • (1997) Clin Pharmacol Ther , vol.61 , pp. 230
    • Vesterqvist, O.1    Liao, W.2    Manning, J.A.3
  • 81
    • 0034686930 scopus 로고    scopus 로고
    • Vasopeptidase inhibition and angio-oedema
    • Messerli FH, Nussberger J. Vasopeptidase inhibition and angio-oedema. Lancet 2000; 356: 608-9.
    • (2000) Lancet , vol.356 , pp. 608-609
    • Messerli, F.H.1    Nussberger, J.2
  • 82
    • 0033862042 scopus 로고    scopus 로고
    • The clinical, cardiac, renal, arterial and neurohormonal effects of omapatrilat, a vasopeptidase inhibitor, in patients with chronic heart failure
    • McClean DR, Ikram H, Garlick AH, Richards AM, Nicholls MG, Crozier IG. The clinical, cardiac, renal, arterial and neurohormonal effects of omapatrilat, a vasopeptidase inhibitor, in patients with chronic heart failure. J Am Coll Cardiol 2000; 36: 479-86.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 479-486
    • McClean, D.R.1    Ikram, H.2    Garlick, A.H.3    Richards, A.M.4    Nicholls, M.G.5    Crozier, I.G.6
  • 83
    • 0034686963 scopus 로고    scopus 로고
    • Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial
    • Rouleau JL, Pfeffer MA, Stewart DJ, Isaac D, Sestier F, Kerut EK, Porter CB, Proulx G, Qian C, Block AJ. Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial. Lancet 2000; 356: 615-20.
    • (2000) Lancet , vol.356 , pp. 615-620
    • Rouleau, J.L.1    Pfeffer, M.A.2    Stewart, D.J.3    Isaac, D.4    Sestier, F.5    Kerut, E.K.6    Porter, C.B.7    Proulx, G.8    Qian, C.9    Block, A.J.10
  • 84
    • 0037143601 scopus 로고    scopus 로고
    • Comparison of omapatrilat and enalapril in patients with chronic heart failure, the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE)
    • Packer M, Califf RM, Konstam MA, Krum H, McMurray JJ, Rouleau JL, Swedberg K. Comparison of omapatrilat and enalapril in patients with chronic heart failure, the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE). Circulation 2002; 106: 920-6.
    • (2002) Circulation , vol.106 , pp. 920-926
    • Packer, M.1    Califf, R.M.2    Konstam, M.A.3    Krum, H.4    McMurray, J.J.5    Rouleau, J.L.6    Swedberg, K.7
  • 85
    • 0036188909 scopus 로고    scopus 로고
    • Effects of captopril and omapatrilat on early post-myocardial infarction survival and cardiac hemodynamics in rats: Interaction with cardiac cytokine expression
    • Blais C Jr, Lapointe N, Rouleau JL, Clement R, Bachvarov DR, Adam A. Effects of captopril and omapatrilat on early post-myocardial infarction survival and cardiac hemodynamics in rats: interaction with cardiac cytokine expression. Can J Physiol Pharmacol 2002; 80: 48-58.
    • (2002) Can J Physiol Pharmacol , vol.80 , pp. 48-58
    • Blais Jr., C.1    Lapointe, N.2    Rouleau, J.L.3    Clement, R.4    Bachvarov, D.R.5    Adam, A.6
  • 86
    • 0033025012 scopus 로고    scopus 로고
    • Effect of long-term therapy with fasidotril, a mixed inhibitor of neprilysin and angiotensin-converting enzyme (ACE), on survival of rats after myocardial infarction
    • Marie C, Mossiat C, Gros C, Schwartz JC, Lecomte JM, Bralet J. Effect of long-term therapy with fasidotril, a mixed inhibitor of neprilysin and angiotensin-converting enzyme (ACE), on survival of rats after myocardial infarction. Cardiovasc Res 1999; 41: 544-53.
    • (1999) Cardiovasc Res , vol.41 , pp. 544-553
    • Marie, C.1    Mossiat, C.2    Gros, C.3    Schwartz, J.C.4    Lecomte, J.M.5    Bralet, J.6
  • 88
    • 0035003857 scopus 로고    scopus 로고
    • In-vitro and in-vivo inhibition of rat neutral endopeptidase and angiotensin converting enzyme with the vasopeptidase inhibitor gemopatrilat
    • Hubner RA, Kubota E, Casley DJ, Johnston CI, Burrell LM. In-vitro and in-vivo inhibition of rat neutral endopeptidase and angiotensin converting enzyme with the vasopeptidase inhibitor gemopatrilat. J Hypertens 2001; 19: 941-6.
    • (2001) J Hypertens , vol.19 , pp. 941-946
    • Hubner, R.A.1    Kubota, E.2    Casley, D.J.3    Johnston, C.I.4    Burrell, L.M.5
  • 89
    • 0037213059 scopus 로고    scopus 로고
    • Renoprotective effects of VPI versus ACEI in normotensive nephrotic rats on different sodium intakes
    • Laverman GD, Van Goor H, Henning RH, De Jong PE, De Zeeuw D, Navis G. Renoprotective effects of VPI versus ACEI in normotensive nephrotic rats on different sodium intakes. Kidney Int 2003; 63: 64-71.
    • (2003) Kidney Int , vol.63 , pp. 64-71
    • Laverman, G.D.1    Van Goor, H.2    Henning, R.H.3    De Jong, P.E.4    De Zeeuw, D.5    Navis, G.6
  • 90
    • 0025775217 scopus 로고
    • Mixed inhibitors of angiotensin-converting enzyme (EC 3.4.15.1) and enkephalinase (EC 3.4.24.11): Rational design, properties, and potential cardiovascular applications of glycopril and alatriopril
    • Gros C, Noel N, Souque A, Schwartz JC, Danvy D, Plaquevent JC, Duhamel L, Duhamel P, Lecomte JM, Bralet J. Mixed inhibitors of angiotensin-converting enzyme (EC 3.4.15.1) and enkephalinase (EC 3.4.24.11): rational design, properties, and potential cardiovascular applications of glycopril and alatriopril. Proc Natl Acad Sci USA 1991; 88: 4210-4.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4210-4214
    • Gros, C.1    Noel, N.2    Souque, A.3    Schwartz, J.C.4    Danvy, D.5    Plaquevent, J.C.6    Duhamel, L.7    Duhamel, P.8    Lecomte, J.M.9    Bralet, J.10
  • 91
    • 0028243301 scopus 로고
    • Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril
    • Bralet J, Marie C, Mossiat C, Lecomte JM, Gros C, Schwartz JC. Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril. J Pharmacol Exp Ther 1994; 270: 8-14.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 8-14
    • Bralet, J.1    Marie, C.2    Mossiat, C.3    Lecomte, J.M.4    Gros, C.5    Schwartz, J.C.6
  • 92
    • 0034110537 scopus 로고    scopus 로고
    • Antihypertensive effects of fasidotril, a dual inhibitor of neprilysin and angiotensin-converting enzyme, in rats and humans
    • Laurent S, Boutouyrie P, Azizi M, Marie C, Gros C, Schwartz JC, Lecomte JM, Bralet J. Antihypertensive effects of fasidotril, a dual inhibitor of neprilysin and angiotensin-converting enzyme, in rats and humans. Hypertension 2000; 35: 1148-53.
    • (2000) Hypertension , vol.35 , pp. 1148-1153
    • Laurent, S.1    Boutouyrie, P.2    Azizi, M.3    Marie, C.4    Gros, C.5    Schwartz, J.C.6    Lecomte, J.M.7    Bralet, J.8
  • 93
    • 0028299371 scopus 로고
    • New dual inhibitors of neutral endopeptidase and angiotensin-converting enzyme: Rational design, bioavailability, and pharmacological responses in experimental hypertension
    • Fournie-Zaluski MC, Coric P, Turcaud S, Rousselet N, Gonzalez W, Barbe B, Pham I, Jullian N, Michel JB, Roques BP. New dual inhibitors of neutral endopeptidase and angiotensin-converting enzyme: rational design, bioavailability, and pharmacological responses in experimental hypertension. J Med Chem 1994; 37: 1070-83.
    • (1994) J Med Chem , vol.37 , pp. 1070-1083
    • Fournie-Zaluski, M.C.1    Coric, P.2    Turcaud, S.3    Rousselet, N.4    Gonzalez, W.5    Barbe, B.6    Pham, I.7    Jullian, N.8    Michel, J.B.9    Roques, B.P.10
  • 94
    • 0028298070 scopus 로고
    • Dual inhibition of angiotensin-converting enzyme and neutral endopeptidase by the orally active inhibitor mixanpril: A potential therapeutic approach in hypertension
    • Fournie-Zaluski MC, Gonzalez W, Turcaud S, Pham I, Roques BP, Michel JB. Dual inhibition of angiotensin-converting enzyme and neutral endopeptidase by the orally active inhibitor mixanpril: a potential therapeutic approach in hypertension. Proc Natl Acad Sci USA 1994; 91: 4072-6.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4072-4076
    • Fournie-Zaluski, M.C.1    Gonzalez, W.2    Turcaud, S.3    Pham, I.4    Roques, B.P.5    Michel, J.B.6
  • 95
    • 0034957092 scopus 로고    scopus 로고
    • Acute effect of the dual angiotensin-converting enzyme and neutral endopeptidase 24-11 inhibitor mixanpril on insulin sensitivity in obese Zucker rat
    • Arbin V, Claperon N, Fournie-Zaluski MC, Roques BP, Peyroux J. Acute effect of the dual angiotensin-converting enzyme and neutral endopeptidase 24-11 inhibitor mixanpril on insulin sensitivity in obese Zucker rat. Br J Pharmacol 2001; 133: 495-502.
    • (2001) Br J Pharmacol , vol.133 , pp. 495-502
    • Arbin, V.1    Claperon, N.2    Fournie-Zaluski, M.C.3    Roques, B.P.4    Peyroux, J.5
  • 96
    • 12244265479 scopus 로고    scopus 로고
    • Effects of dual Angiotensin-converting enzyme and neutral endopeptidase 24-11 chronic inhibition by mixanpril on insulin sensitivity in lean and obese zucker rats
    • Arbin V, Claperon N, Fournie-Zaluski MC, Roques BP, Peyroux J. Effects of dual Angiotensin-converting enzyme and neutral endopeptidase 24-11 chronic inhibition by mixanpril on insulin sensitivity in lean and obese zucker rats. J Cardiovasc Pharmacol 2003; 41: 254-64.
    • (2003) J Cardiovasc Pharmacol , vol.41 , pp. 254-264
    • Arbin, V.1    Claperon, N.2    Fournie-Zaluski, M.C.3    Roques, B.P.4    Peyroux, J.5
  • 97
    • 0033770641 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study to assess tolerability, pharmacokinetics and preliminary pharmacodynamics of single escalating doses of Z13752A, a novel dual inhibitor of the metalloproteases ACE and NEP, in healthy volunteers
    • Bani M, Colantoni A, Guillaume M, Macchi F, Moroni G, Persiani S. A double-blind, placebo-controlled study to assess tolerability, pharmacokinetics and preliminary pharmacodynamics of single escalating doses of Z13752A, a novel dual inhibitor of the metalloproteases ACE and NEP, in healthy volunteers. Br J Clin Pharmacol 2000; 50: 338-49.
    • (2000) Br J Clin Pharmacol , vol.50 , pp. 338-349
    • Bani, M.1    Colantoni, A.2    Guillaume, M.3    Macchi, F.4    Moroni, G.5    Persiani, S.6
  • 98
    • 0034098974 scopus 로고    scopus 로고
    • The effects of Z13752A, a combined ACE/NEP inhibitor, on responses to coronary artery occlusion; a primary protective role for bradykinin
    • Rastegar MA, Marchini F, Morazzoni G, Vegh A, Papp JG, Parratt JR. The effects of Z13752A, a combined ACE/NEP inhibitor, on responses to coronary artery occlusion; a primary protective role for bradykinin. Br J Pharmacol 2000; 129: 671-80.
    • (2000) Br J Pharmacol , vol.129 , pp. 671-680
    • Rastegar, M.A.1    Marchini, F.2    Morazzoni, G.3    Vegh, A.4    Papp, J.G.5    Parratt, J.R.6
  • 99
    • 0031434320 scopus 로고    scopus 로고
    • Comparative effects of the dual metallopeptidase inhibitor, MDL 100,240 and of enalaprilat on regional and on cardiac haemodynamics in conscious, hypertensive, transgenic ((mRen-2)27) rats
    • Gardiner SM, Kemp PA, Brunner-Ferber F, Bennett T. Comparative effects of the dual metallopeptidase inhibitor, MDL 100,240 and of enalaprilat on regional and on cardiac haemodynamics in conscious, hypertensive, transgenic ((mRen-2)27) rats. Br J Pharmacol 1997; 122: 1694-701.
    • (1997) Br J Pharmacol , vol.122 , pp. 1694-1701
    • Gardiner, S.M.1    Kemp, P.A.2    Brunner-Ferber, F.3    Bennett, T.4
  • 100
    • 0036628768 scopus 로고    scopus 로고
    • Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor
    • Rossi GP, Cavallin M, Rizzoni D, Bova S, Mazzocchi G, Agabiti-Rosei E, Nussdorfer GG, Pessina AC. Dual ACE and NEP inhibitor MDL-100,240 prevents and regresses severe angiotensin II-dependent hypertension partially through bradykinin type 2 receptor. J Hypertens 2002; 20: 1451-9.
    • (2002) J Hypertens , vol.20 , pp. 1451-1459
    • Rossi, G.P.1    Cavallin, M.2    Rizzoni, D.3    Bova, S.4    Mazzocchi, G.5    Agabiti-Rosei, E.6    Nussdorfer, G.G.7    Pessina, A.C.8
  • 101
    • 0036179428 scopus 로고    scopus 로고
    • Comparative effects of the dual ACE-NEP inhibitor MDL-100,240 and ramipril on hypertension and cardiovascular disease in endogenous angiotensin II-dependent hypertension
    • Rossi GP, Bova S, Sacchetto A, Rizzoni D, Agabiti-Rosei E, Neri G, Nussdorfer GG, Pessina AC. Comparative effects of the dual ACE-NEP inhibitor MDL-100,240 and ramipril on hypertension and cardiovascular disease in endogenous angiotensin II-dependent hypertension. Am J Hypertens 2002; 15: 181-8.
    • (2002) Am J Hypertens , vol.15 , pp. 181-188
    • Rossi, G.P.1    Bova, S.2    Sacchetto, A.3    Rizzoni, D.4    Agabiti-Rosei, E.5    Neri, G.6    Nussdorfer, G.G.7    Pessina, A.C.8
  • 102
    • 0037341656 scopus 로고    scopus 로고
    • Vasopeptidase inhibition: A double-edged sword?
    • Campbell DJ. Vasopeptidase inhibition: a double-edged sword? Hypertension 2003; 41: 383-9.
    • (2003) Hypertension , vol.41 , pp. 383-389
    • Campbell, D.J.1
  • 103
    • 0031666168 scopus 로고    scopus 로고
    • Combined inhibition of neutral endopeptidase and angiotensin-converting enzyme by sampatrilat in essential hypertension
    • Wallis EJ, Ramsay LE, Hettiarachchi J. Combined inhibition of neutral endopeptidase and angiotensin-converting enzyme by sampatrilat in essential hypertension. Clin Pharmacol Ther 1998; 64: 439-49.
    • (1998) Clin Pharmacol Ther , vol.64 , pp. 439-449
    • Wallis, E.J.1    Ramsay, L.E.2    Hettiarachchi, J.3
  • 104
    • 0033059782 scopus 로고    scopus 로고
    • Sustained antihypertensive actions of a dual angiotensin-converting enzyme neutral endopeptidase inhibitor, sampatrilat, in black hypertensive subjects
    • Norton GR, Woodiwiss AJ, Hartford C, Trifunovic B, Middlemost S, Lee A, Allen MJ. Sustained antihypertensive actions of a dual angiotensin-converting enzyme neutral endopeptidase inhibitor, sampatrilat, in black hypertensive subjects. Am J Hypertens 1999; 12: 563-71.
    • (1999) Am J Hypertens , vol.12 , pp. 563-571
    • Norton, G.R.1    Woodiwiss, A.J.2    Hartford, C.3    Trifunovic, B.4    Middlemost, S.5    Lee, A.6    Allen, M.J.7
  • 105
    • 0037382479 scopus 로고    scopus 로고
    • Beneficial Effects of Sampatrilat, a Novel Vasopeptidase Inhibitor, on Cardiac Remodeling and Function of Rats with Chronic Heart Failure following Left Coronary Artery Ligation
    • Maki T, Nasa Y, Tanonaka K, Takahashi M, Takeo S. Beneficial Effects of Sampatrilat, a Novel Vasopeptidase Inhibitor, on Cardiac Remodeling and Function of Rats with Chronic Heart Failure following Left Coronary Artery Ligation. J Pharmacol Exp Ther 2003; 305: 97-105.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 97-105
    • Maki, T.1    Nasa, Y.2    Tanonaka, K.3    Takahashi, M.4    Takeo, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.