Management of Frey's syndrome and hypersialorrhea with botulinum toxin

Facial Plastic Surgery Clinics of North America

Volumn 11, Issue 4, 2003, Pages 503-513

  Guntinas Lichius, Orlando ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BOTULINUM TOXIN A; BOTULINUM TOXIN B;

ARTICLE; CLINICAL EXAMINATION; CLINICAL TRIAL; DIAGNOSTIC TEST; DISEASE EXACERBATION; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DYSPHAGIA; FACE MUSCLE; FACIAL NERVE INJURY; FREY SYNDROME; HEAD AND NECK DISEASE; HUMAN; HYPERSALIVATION; NEUROLOGIC DISEASE; PARESIS; PARESTHESIA; SALIVARY GLAND DISEASE; SIDE EFFECT; SURGICAL TECHNIQUE; XEROSTOMIA;

EID: 0347126608     PISSN: 10647406     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1064-7406(03)00075-0     Document Type: Review

References (58)

1. Blitzer A, Sulica L. Botulinum toxin: basic science and clinical uses in otolaryngology. Laryngoscope 2001; 111(2):218-26.
2. Blitzer A, Brin MF, Stewart CF. Botulinum toxin management of spasmodic dysphonia (laryngeal dystonia): a 12-year experience in more than 900 patients. Laryngoscope 1998;108(10):1435-41.
3. Laskawi R, Ellies M, Drobik C, Batz A. Botulinum toxin treatment in patients with hemifacial spasm. Eur Arch Otorhinolaryngol 1994;251(5):271-4.
4. American Academy of Otolaryngology - Head & Neck Surgery. Policy statement: botulinum toxin. Revised April 9, 1997; reaffirmed March 1998.
5. Marchese RR, Blotta P, Pastore A, Tugnoli V, Eleopra R, De Grandis D. Management of parotid sialocele with botulinum toxin. Laryngoscope 1999;109(8): 1344-6.
6. Guntinas-Lichius O, Sittel C. Treatment of postparotidectomy salivary fistula with botulinum toxin. Ann Otol Rhinol Laryngol 2001;110(12):1162-4.
7. Guntinas-Lichius O, Eckel HE. Temporary reduction of salivation in laryngectomy patients with pharyngocutaneous fistulas by botulinum toxin A injection. Laryngoscope 2002;112(1):187-9.
8. Jost WH. Treatment of drooling in Parkinson's disease with botulinum toxin. Mov Disord 1999;14(6):1057.
9. Porta M, Gamba M, Bertacchi G, Vaj P. Treatment of sialorrhoea with ultrasound guided botulinum toxin type A injection in patients with neurological disorders. J Neurol Neurosurg Psychiatry 2001;70(4):538-40.
10. Dulguerov P, Marchal F, Gysin C. Frey syndrome before Frey: the correct history. Laryngoscope 1999; 109(9):1471-3.
11. Minor V. Ein neues Verfahren zu der klinischen Untersuchung der Schweißabsonderung [A new technique for the clinical examination of sweating]. Dt Z Nervenheilk 1928;101:302-9 [in German].
12. Laskawi R, Drobrik C, Schönebeck C. Up-to-date report of botulinum toxin type A treatment in patients with gustatory sweating. Laryngoscope 1998;108: 381-4.
13. Haxton HA. Gustatory sweating. Brain 1948;71: 16-25.
14. Spiro RH, Martin H. Gustatory sweating following parotid surgery and radical neck dissection. Ann Surg 1967;165(1):118-27.
15. Arad-Cohen A, Blitzer A. Botulinum toxin treatment for symptomatic Frey's syndrome. Otolaryngol Head Neck Surg 2000;122(2):237-40.
16. Kurchin A, Adar R, Zweig A, Mozes M. Gustatory phenomena after upper dorsal sympathectomy. Arch Neurol 1977;34(10):619-23.
17. Watkins PJ. Facial sweating after food: a new sign of diabetic autonomic neuropathy. BMJ 1973;1:583-7.
18. Teague A, Akhtar S, Phillips J, Frey's syndrome following submandibular gland excision: an unusual postoperative complication. ORL J Otorhinolaryngol Relat Spec 1998;60(6):346-8.
19. Parkash S, Ramakrishnan K. Gustatory syndrome following radical neck dissection. Aust N Z J Surg 1983;53(5):491-2.
20. Lin TS, Wang NP, Huang LC. Pitfalls and complication avoidance associated with transthoracic endoscopic sympathectomy for primary hyperhidrosis (analysis of 2200 cases). Int J Surg Investig 2001;2(5):377-8.
21. Ford FR, Woodhall B. Phenomena due to misdirection of regenerating fibers of cranial, spinal and autonomic nerves. Arch Surg 1938;36:480-96.
22. Dulguerov P, Quinodoz D, Cosendai G, Piletta P, Lehmann W. Frey syndrome treatment with botulinum toxin. Otolaryngol Head Neck Surg 2000;122(6): 821-7.
23. Laccourreye O, Bonan B, Brasnu D, Laccourreye H. Treatment of Frey's syndrome with topical 2% diphemanil methylsulfate (Prantal): a double-blind evaluation of 15 patients. Laryngoscope 1990;100(6):651-3.
24. Golding-Wood PH. Tympanic neurectomy. J Laryngol Otol 1962;76:683-93.
25. Hays LL. The Frey syndrome: a review and double blind evaluation of the topical use of a new anticholinergic agent. Laryngoscope 1978;88:1796-824.
26. Laskawi R, Ellies M, Rodel R, Schoenebeck C. Gustatory sweating: clinical implications and etiologic aspects. J Oral Maxillofac Surg 1999;57(6):642-8.
27. Tugnoli V, Marchese RR, Eleopra R, Quatrale R, Capone JG, Pastore A, et al. The role of gustatory flushing in Frey's syndrome and its treatment with botulinum toxin type A. Clin Auton Res 2002;12(3):174-8.
28. Wohlfarth K, Goschel H, Frevert J, Dengler R, Bigalke H. Botulinum A toxins: units versus units. Naunyn Schmiedebergs Arch Pharmacol 1997;355(3):335-40.
29. Guyer BM. Some unresolved issues with botulinum toxin. J Neurol 2001;248(Suppl 1):11-3.
30. Guntinas-Lichius O. Increased botulinum toxin type A dosage is more effective in patients with Frey's syndrome. Laryngoscope 2002;112(4):746-9.
31. Naumann M, Zellner M, Toyka KV, Reiners K. Treatment of gustatory sweating with botulinum toxin. Ann Neurol 1997;42(6):973-5.
32. Bjerkhoel A, Trobbe O. Frey's syndrome: treatment with botulinum toxin. J Laryngol Otol 1997;111(9): 839-44.
33. Laccourreye O, Muscatello L, Naude C, Bonan B, Brasnu D. Botulinum toxin type A for Frey'syndrome: a preliminary prospective study. Ann Otol Rhinol Laryngol 1998;107:52-5.
34. Laccourreye O, Akl E, Gutierrez-Fonseca R, Garcia D, Brasnu D, Bonan B. Recurrent gustatory sweating (Frey syndrome) after intracutaneous injection of botulinum toxin type A: incidence, management, and outcome. Arch Otolaryngol Head Neck Surg 1999;125(3): 283-6.
35. von Lindern JJ, Niederhagen B, Berge S, Hagler G, Reich RH. Frey syndrome: treatment with type A botulinum toxin. Cancer 2000;89(8):1659-63.
36. Küttner C, Berens A, Troger M, Keil C, Eckardt A. [Frey syndrome after lateral parotidectomy. Follow-up and therapeutic outlook]. Mund Kiefer Gesichtschir 2001;5(2):144-9 [in German].
37. Restivo DA, Lanza S, Patti F, Giuffrida S, Marchese-Ragona R, Bramanti P, et al. Improvement of diabetic autonomic gustatory sweating by botulinum toxin type A. Neurology 2002;59(12):1971-3.
38. Guntinas-Lichius O. Injection of botulinum toxin type B for the treatment of otolaryngology patients with secondary treatment failure of botulinum toxin type A. Laryngoscope 2003;113(4):743-5.
39. Aoki KR. Pharmacology and immunology of botulinum toxin serotypes. J Neurol 2001;248(Suppl 1): 3-10.
40. Glickman S, Deaney CN. Treatment of relative sialorrhoea with botulinum toxin type A: description and rationale for an injection procedure with case report. Eur J Neurol 2001;8(6):567-71.
41. Guntinas-Lichius O, Eckel HE. Temporary reduction of salivation in laryngectomy patients with pharyngocutaneous fistulas by botulinum toxin A injection. Laryngoscope 2002;112(1):187-9.
42. Jongerius PH, Rotteveel JJ, van den HF, Joosten F, van Hulst K, Gabreels FJ. Botulinum toxin A: a new option for treatment of drooling in children with cerebral palsy. Presentation of a case series. Eur J Pediatr 2001; 160(8):509-12.
43. Arnold HG, Gross CW. Transtympanic neurectomy: a solution to drooling problems. Dev Med Child Neurol 1977;19(4):509-13.
44. Mankarious LA, Bottrill ID, Huchzermeyer PM, Bailey CM. Long-term follow-up of submandibular duct rerouting for the treatment of sialorrhea in the pediatric population. Otolaryngol Head Neck Surg 1999;120(3): 303-7.
45. Crysdale WS, Raveh E, McCann C, Roske L, Kotler A. Management of drooling in individuals with neurodisability: a surgical experience. Dev Med Child Neurol 2001;43(6):379-83.
46. Tscheng DZ. Sialorrhea - therapeutic drug options. Ann Pharmacother 2002;36(11):1785-90.
47. Shaari CM, Wu BL, Biller HF, Chuang SK, Sanders I. Botulinum toxin decreases salivation from canine submandibular glands. Otolaryngol Head Neck Surg 1998; 118(4):452-7.
48. Ellies M, Laskawi R, Gotz W, Arglebe C, Tormahlen G. Immunohistochemical and morphometric investigations of the influence of botulinum toxin on the submandibular gland of the rat. Eur Arch Otorhinolaryngol 1999;256(3):148-52.
49. Ellies M, Laskawi R, Tormahlen G, Gotz W. The effect of local injection of botulinum toxin A on the parotid gland of the rat: an immunohistochemical and morphometric study. J Oral Maxillofac Surg 2000;58(11): 1251-6.
50. Pal PK, Calne DB, Calne S, Tsui JK. Botulinum toxin A as treatment for drooling saliva in PD. Neurology 2000;54(1):244-7.
51. Ellies M, Laskawi R, Rohrbach-Volland S, Arglebe C, Beuche W. Botulinum toxin to reduce saliva flow: selected indications for ultrasound-guided toxin application into salivary glands. Laryngoscope 2002;112(2): 82-6.
52. Suskind DL, Tilton A. Clinical study of botulinum-A toxin in the treatment of sialorrhea in children with cerebral palsy. Laryngoscope 2002;112(1):73-81.
53. Ekedahl C. Surgical treatment of drooling. Acta Otolaryngol 1974;77(3):215-20.
54. Giess R, Naumann M, Werner E, Riemann R, Beck M, Puls I, et al. Injections of botulinum toxin A into the salivary glands improve sialorrhoea in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 2000; 69(1):121-3.
55. Ellies M, Rohrbach-Volland S, Arglebe C, Wilken B, Laskawi R, Hanefeld F. Successful management of drooling with botulinum toxin A in neurologically disabled children. Neuropediatrics 2002;33(6):327-30.
56. Bothwell JE, Clarke K, Dooley JM, Gordon KE, Anderson R, Wood EP, et al. Botulinum toxin A as a treatment for excessive drooling in children. Pediatr Neurol 2002;27(1):18-22.
57. Jongerius PH, Joosten F, Hoogen FJ, Gabreels FJ, Rotteveel JJ. The treatment of drooling by ultrasound-guided intraglandular injections of botulinum toxin type A into the salivary glands. Laryngoscope 2003; 113(1):107-11.
58. Ellies M, Laskawi R, Rohrbach-Volland S, Arglebe C. Up-to-date report of botulinum toxin therapy in patients with drooling caused by different etiologies. J Oral Maxillofac Surg 2003;61(4):454-7.