Sterol Methyltransferase: Functional Analysis of Highly Conserved Residues by Site-Directed Mutagenesis

Biochemistry

Volumn 43, Issue 2, 2004, Pages 569-576

  Nes, W David ^a   Jayasimha, Pruthvi ^a   Zhou, Wenxu ^a   Kanagasabai, Ragu ^a   Jin, Changxiao ^c   Jaradat, Tahhan T ^a   Shaw, Robert W ^a   Bujnicki, Janusz M ^b  

^a TEXAS TECH UNIVERSITY   (United States)

^b INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYST ACTIVITY; ENZYMES; ESCHERICHIA COLI; PH EFFECTS; PROTEINS;

METHYLATION;

MUTAGENESIS;

ASPARTIC ACID; GLUTAMIC ACID; HISTIDINE; LEUCINE; METHYLTRANSFERASE; MUTANT PROTEIN; STEROL; STEROL METHYLTRANSFERASE; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; AMINO ACID COMPOSITION; ARTICLE; CHROMATOGRAPHY; CIRCULAR DICHROISM; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME MECHANISM; EQUILIBRIUM CONSTANT; ESCHERICHIA COLI; GENETIC CONSERVATION; METHYLATION; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON TRANSPORT; SACCHAROMYCES CEREVISIAE; SITE DIRECTED MUTAGENESIS; WILD TYPE;

ASPARTIC ACID; CATALYSIS; CIRCULAR DICHROISM; CONSERVED SEQUENCE; GLUTAMIC ACID; METHYLTRANSFERASES; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI; NEGIBACTERIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0347093468     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035257z     Document Type: Article

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