Canine Narcolepsy and the Role of the Nervous System

Compendium on Continuing Education for the Practicing Veterinarian

Volumn 21, Issue 7, 1999, Pages 641-650

  Coleman, Elaine S ^a  

^a TUSKEGEE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0347083309     PISSN: 01931903     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (69)

1. Nishino S, Mignot E: Pharmacological aspects of human and canine narcolepsy. Prog Neurobiol 52:27-78, 1997.
2. Aldrich MS: Sleep-related spells associated with parasomnias and narcolepsy. Semin Neurol 15:194-202, 1995.
3. Aldrich MS: Narcolepsy. Neurology 42:34-43, 1992.
4. Nishino S, Tafti M, Sampathkumaran R, et al: Circadian distribution of rest/activity in narcoleptic and control dogs: Assessment with ambulatory activity monitoring. J Sleep Res 6:120-127, 1997.
5. Kaitin KI, Kilduff TS, Dement WC: Sleep fragmentation in genetically narcoleptic dogs. Sleep 9:116-119, 1986.
6. Lucas EA, Foutz AS, Mitler MM, et al: Multiple sleep latency test in normal and narcoleptic canines. Soc Neurosci Abst 4:451, 1978.
7. Mitler MM, Dement WC: Sleep studies on canine narcolepsy: Pattern and cycle comparisons between affected and normal dogs. Electroencephalogr Clin Neurophysiol 43:691-699, 1977.
8. Shell L: Sleep disorders, in Ettinger SJ, Feldman EC (eds): Textbook of Veterinary Internal Medicine. Philadelphia, WB Saunders Co, 1995, pp 157-158.
9. Lunn DP, Cuddon PA, Shaftoe S, Archer RM: Familial occurrence of narcolepsy in miniature horses. Equine Vet J 25: 483-487, 1993.
10. Dreifuss FE, Flynn DV: Narcolepsy in a horse. JAVMA 184:131-132, 1984.
11. Strain GM, Olcott BM, Archer RM, McClintock BK: Narcolepsy in a Brahman bull. JAVMA 185:538-541, 1984.
12. Sweeney CR, Hendricks JC, Beech J, Morrison AR: Narcolepsy in a horse. JAVMA 183:126-128, 1983.
13. Katherman AE: A comparative review of canine and human narcolepsy. Compend Contin Educ Pract Vet 2(10):818-822, 1980.
14. Knecht CD, Oliver JE, Redding R, et al: Narcolepsy in a dog and a cat. JAVMA 162:1052-1053, 1973.
15. Chrisman CL: Problems in Small Animal Neurology, ed 2. Philadelphia, Lea & Febiger, 1991, pp 223-225.
16. Foutz AS, Mitler MM, Dement WC: Narcolepsy. Vet Clin North Am Small Anim Pract 10:65-80, 1980.
17. Baker TL, Mitler MM, Foutz AS, Dement WC: Diagnosis and treatment of narcolepsy in animals, in Kirk RW (ed): Current Veterinary Therapy VIII. Small Animal Practice. Philadelphia, WB Saunders Co, 1983, pp 755-759.
18. Riehl J, Nishino S, Cederberg R, et al: Development of cataplexy in genetically narcoleptic Dobermans. Exper Neurol 152:292-302, 1998.
19. Wauquier A, Verheyen JL, Van Den Broeck WAE, Janssen PAJ: Visual and computer-based analysis of 24 h sleep-waking patterns in the dog. Electroencephalogr Clin Neurophys 46:33-48, 1979.
20. Macquet P: Positron emission tomography studies of sleep and sleep disorders. J Neurol 244 (4)(Suppl 1):S23-S28, 1997.
21. Burt AM: Textbook of Neuroanatomy. Philadelphia, WB Saunders Co, 1993, pp 474-478.
22. Jones BE: Paradoxical sleep and its chemical/structural substrates in the brain. Neuroscience 40:637-656, 1991.
23. Hobson JA: Sleep and dreaming. J Neurosci 10:371-382, 1990.
24. Hendricks JC, Morrison AR: Normal and abnormal sleep in mammals. JAVMA 178:121-126, 1981.
25. Jones BE, Yang TZ: The efferent projections from the reticular formation and the locus coeruleus studied by anterograde and retrograde axonal transport in the rat. J Comp Neurol 242:56-92, 1985.
26. Jones BE, Moore RY: Catecholamine-containing neurons of the nucleus locus coeruleus in the cat. J Comp Neurol 157: 43-52, 1974.
27. Steriade M: Basic mechanisms of sleep generation. Neurology 42:9-18, 1992.
28. Steriade M, Datta S, Paré D, et al: Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocortical systems. J Neurosci 10:2541-2559, 1990.
29. Rye DB: Contributions of the pedunculopontine region to normal and altered REM sleep. Sleep 20:757-788, 1997.
30. Mitler MM, Dement WC: Cataplexy-like behavior in cats after microinjection of carbachol in pontine reticular formation. Brain Res 68:335-343, 1974.
31. Jones BE: Immunohistochemical study of choline acetyltransferase-immunoreactive processes and cells innervating the pontomedullary reticular formation in the rat. J Comp Neurol 295:485-514, 1990.
32. Sakai K: Neurons responsible for paradoxical sleep, in Wauquier A, Gaillard JM, Mond JM, Radulovaki M (eds): Sleep: Neurotransmitters and Neuromodulators. New York, Raven, 1985, pp 29-42.
33. Jones BE, Beaudet A: Distribution of acetylcholine and catecholamine neurons in the cat brainstem: A choline acetyltransferase and tyrosine hydroxylase immunohistochemical study. J Comp Neurol 261:15-32, 1987.
34. Dement WC, Carskadon M, Ley R: The prevalence of narcolepsy II. Sleep Res 2:147, 1973.
35. Guilleminault C, Mignot E, Grumet FC: Familial patterns of narcolepsy. Lancet 2:1376-1379, 1989.
36. Bassetti C, Aldrich MS: Narcolepsy. Neurol Clin 14:545-571, 1996.
37. Kessler S, Guilleminault C, Dement W: A family study of 50 REM narcoleptics. Acta Neurol Scand 50:503-512, 1974.
38. Braund KG: Clinical Syndromes in Veterinary Neurology, ed 2. St. Louis, Mosby, 1994, pp 196-198.
39. Foutz AS, Mitler MM, Cavalli-Sforza L, Dement WC: Genetic factors in canine narcolepsy. Sleep Res 1:412-413, 1979.
40. Baker T, Foutz A, Neyman V, Dement W: Canine model of narcolepsy: Genetic and developmental determinants. Exp Neurol75:729-742, 1982.
41. Reid MS, Tafti M, Geary JN, et al: Cholinergic mechanisms in canine narcolepsy - I. Modulation of cataplexy via local drug administration into the pontine reticular formation. Neuroscience 59:511-522, 1994.
42. Reid MS, Tafti M, Geary JN, et al: Cholinergic mechanisms in canine narcolepsy - II. Acetylcholine release in the pontine reticular formation is enhanced during cataplexy. Neuroscience 59:523-530, 1994.
43. Nishino S, Tafti M, Reid MS, et al: Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: Implication for the pathophysiology of narcolepsy. J Neurosci 15:4806-4814, 1995.
44. Nishino S, Reid MS, Dement WC, Mignot E: Neuropharmacology and neurochemistry of canine narcolepsy. Sleep 17:S84-S92, 1994.
45. Nishino S, Haak L, Shepherd H, et al: Effects of central alpha-2 adrenergic compounds on canine narcolepsy, a disorder of rapid eye movement sleep. J Pharmacol Expl Ther 253:1145-1152, 1990.
46. Mignot E, Nishino S, Hunt Sharp LE, et al: Heterozygosity of the canarc-1 locus can confer susceptibility for narcolepsy: Induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems. J Neurosci 13: 1057-1064, 1993.
47. Nishino S, Mao J, Sampathkumaran R, et al: Differential effects of dopaminergic and noradrenergic uptake inhibitors on EEG arousal and cataplexy of narcoleptic canines. Sleep Res 25:317, 1996.
48. Kilduff T, Bowersox SS, Kaitan KI, et al: Muscarinic cholinergic receptors and the canine model of narcolepsy. Sleep 9:102-107, 1986.
49. Boehme R, Baker T, Mefford I, et al: Narcolepsy: Cholinergic receptor changes in an animal model. Life Sci 34:1825-1828, 1984.
50. 1 adrenoreceptor blockade with prazosin in canine narcolepsy. Brain Res 444:184-188, 1988.
51. 2 receptors in the locus coeruleus. Brain Res 500:209-214, 1989.
52. Bowersox SS, Kilduff T, Faull K, et al: Brain dopamine receptor levels elevated in canine narcolepsy. Brain Res 402: 44-48, 1987.
53. Guilleminault C, Heinzer R, Mignot E, Black J: Investigations into the neurologic basis of narcolepsy. Neurology 50: S8-S15, 1998.
54. Carlander B, Eliaou JF, Billard M: Autoimmune hypothesis in narcolepsy. Neurophysiol Clin 23:15-22, 1993.
55. Mignot E, Tafti M, Dement WC, Grumet FC: Narcolepsy and immunity. Adv Neuroimmunol 5:23-37, 1995.
56. Mignot E, Wang C, Rattazzi C, et al: Genetic linkage of autosomal recessive canine narcolepsy with an immunoglobulin μ chain switch-like segment. Proc Natl Acad Sci USA 88:3475-3478, 1991.
57. Tafti M, Nishino S, Aldrich MS, et al: Major histocompatibility class II molecules in the CNS: Increased microglial expression at the onset of narcolepsy in canine model. J Neurosci 16:4588-4595, 1996.
58. Tafti M, Nishino S, Dement WC, Mignot E: Narcolepsy is associated with increased microglial expression of MHC class II molecules. Sleep Res 24A:372, 1995.
59. Oliver JE, Lorenz MD: Handbook of Veterinary Neurology, ed 2. Philadelphia, WB Saunders Co, 1993, pp 308-309.
60. Hendricks JC, Hughes C: Treatment of cataplexy in a dog with narcolepsy JAVMA 194:791-792, 1989.
61. Van Heerden J, Eckersley GN: Narcolepsy in a long-haired dachshund. J S Afr Vet Assoc 60:151-153, 1989.
62. Cooper JR, Bloom FE, Roth RH: The Biochemical Basis of Neuropharmacology, ed 7. New York, Oxford University Press, 1996, pp 282-285.
63. Nishino S, Arrigoni J, Shelton J, et al: Desmethyl metabolites of serotonergic uptake inhibitors are more potent for suppressing canine cataplexy than their parent compounds. Sleep 16:706-712, 1993.
64. Mitler MM, Soave O, Dement WC: Narcolepsy in seven dogs. JAVMA 168:1036-1038, 1976.
65. Shores A, Redding RW: Narcoleptic hypersomnia syndrome responsive to protriptyline in a Labrador retriever. JAAHA 23:455-458, 1987.
66. Overall KL: Pharmacologic treatments for behavior problems. Vet Clin North Am Small Anim Pract 27:637-664, 1997.
67. Johnson LR: Tricyclic antidepressant toxicosis. Vet Clin North Am Small Anim Pract 20:393-403, 1990.
68. Nishino S, Arrigoni J, Kanbayashi T, et al: Comparative effects of MAO-a and MAO-b selective inhibitors on canine cataplexy. Sleep Res 25:315, 1996.
69. Milgram NW, Ivy GO, Head E, et al: The effect of L-deprenyl on behavior, cognitive function, and biogenic amines in the dog. Neurochem Res 18:1211-1219, 1993.