Insertion of an N7-methylguanine mRNA Cap between Two Coplanar Aromatic Residues of a Cap-binding Protein Is Fast and Selective for a Positively Charged Cap

Journal of Biological Chemistry

Volumn 278, Issue 51, 2003, Pages 51515-51520

  Hu, Guanghui ^a,c   Tsai, Ah Lim ^b   Quiocho, Florante A ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; FLUORESCENCE; ISOMERS; PH EFFECTS; PROTEINS; RATE CONSTANTS; REACTION KINETICS; RNA; VIRUSES;

CAP BINDING;

BIOCHEMISTRY;

7 METHYLGUANINE; BINDING PROTEIN; MESSENGER RNA;

ALKYLATION; ARTICLE; COMPLEX FORMATION; DISSOCIATION CONSTANT; DNA REPAIR; ENZYME SPECIFICITY; GENE INSERTION; LIGAND BINDING; MESSENGER RNA SYNTHESIS; METHYLATION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; RESIDUE ANALYSIS; RNA TRANSCRIPTION; TRANSCRIPTION REGULATION; VACCINIA VIRUS;

AMINO ACIDS, AROMATIC; BINDING SITES; CATIONS; GUANINE; HYDROGEN-ION CONCENTRATION; KINETICS; RNA CAP-BINDING PROTEINS; RNA CAPS; TIME FACTORS; VIRAL PROTEINS;

EUKARYOTA; INSERTION SEQUENCES; VACCINIA VIRUS;

EID: 0347065346     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307654200     Document Type: Article

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