Telomerase Activity in Chronic Inflammatory Bowel Disease

Digestive Diseases and Sciences

Volumn 48, Issue 12, 2003, Pages 2328-2332

  Kleideiter, Elke ^a   Friedrich, Ulrike ^a,f   Möhring, Alexandra ^a   Walker, Siegfried ^b   Höring, Emil ^c   Maier, Karlernst ^d   Fritz, Peter ^e   Thon, Klaus Peter ^e   Klotz, Ulrich ^a  

^a DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^b Hospital Bietigheim Bissingen   (Germany)

^c Gastroenterol Oncol Grp Pract   (Germany)

^d Klinikum Stuttgart Krankenhaus Bad Cannstatt   (Germany)

^e ROBERT BOSCH HOSPITAL   (Germany)

^f Clinical Center Villingen Schwenningen   (Germany)

Author keywords

Colon cancer; Crohn's disease; Telomerase; Tumor marker; Ulcerative colitis

Indexed keywords

TELOMERASE; TUMOR MARKER;

ARTICLE; CARCINOGENESIS; CELL IMMORTALIZATION; CHRONIC INFLAMMATION; CLINICAL ARTICLE; COLON ADENOCARCINOMA; COLORECTAL CANCER; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; INTESTINE BIOPSY; INTESTINE MUCOSA; PRECANCER; PRIORITY JOURNAL; PROGNOSIS; SCORING SYSTEM; ULCERATIVE COLITIS;

ADULT; CASE-CONTROL STUDIES; CELL TRANSFORMATION, NEOPLASTIC; COLITIS, ULCERATIVE; CROHN DISEASE; FEMALE; HUMANS; INFLAMMATORY BOWEL DISEASES; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; SEVERITY OF ILLNESS INDEX; TELOMERASE; TUMOR MARKERS, BIOLOGICAL;

EID: 0347064069     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:DDAS.0000007871.86129.4a     Document Type: Article

References (25)

1. Ekbom A, Helmick C, Zack M, Adami HO: Ulcerative colitis and colorectal cancer. A population-based study. N Engl J Med 323:1228-1233, 1990
2. Brentnall TA: Risk factors for development of colorectal cancer in inflammatory bowel disease. In Advances in Inflammatory Bowel Diseases. P Rutgeerts, JF Colombel, SB Hanauer, J Schölmerich, GNJ Tytgat, A van Gossum (eds). Dordrecht/Boston/London, Kluwer Academic, 1999, pp 159-167
3. Ullmann TA: Cancer in inflammatory bowel disease. Curr Treat Opt Gastroenterol 5:163-171, 2002
4. Gwyn K, Sinicrope FA: Chemoprevention of colorectal cancer. Am J Gastroenterol 97:13-21, 2002
5. Dhaene K, van Marck E, Parwaresch R: Telomeres, telomerase and cancer: an up-date. Virchows Arch 437:1-16, 2000
6. Chadeneau C, Hay K, Hirte HW, Gallinger S, Bacchetti S: Telomerase activity associated with acquisition of malignancy in human colorectal Cancer. Cancer Res 55:2533-2536, 1995
7. Tahara H, Kuniyasu H, Yokozaki H, Yasui W, Shay JW, Ide T, Tahara E: Telomerase activity in preneoplastic and neoplastic gastric and colorectal lesions. Clin Cancer Res 1:1245-1251, 1995
8. Engelhardt M, Albanell J, Drullinsky P, Han W, Guillem J, Scher HI, Reuter V, Moore MA: Relative contribution of normal and neoplastic cells determines telomerase activity and telomere length in primary cancers of the prostate, colon, and sarcoma. Clin Cancer Res 3:1849-1857, 1997
9. Engelhardt M, Drullinsky P, Guillem J, Moore MA: Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer. Clin Cancer Res 3:1931-1941, 1997
10. Tahara H, Yasui W, Tahara E, Fujimoto J, Ito K, Tamai K, Nakayama J, Ishikawa F, Tahara E, Ide T: Immuno-histochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections. Oncogene 18:1561-1567, 1999
11. Fang DC, Young J, Luo YH, Lu R, Jass J: Detection of telomerase activity in biopsy samples of colorectal cancer. J Gastroenterol Hepatol 14:328-332, 1999
12. Yan P, Saraga EP, Bouzourene H, Bosman FT, Benhattar J: Telomerase activation in colorectal carcinogenesis. J Pathol 189:207-212, 1999
13. Yoshida R, Kiyozuka Y, Ichiyoshi H, Senzaki H, Takada H, Hioki K, Tsubura A: Change in telomerase activity during human colorectal carcinogenesis. Anticancer Res 19:2167-2172, 1999
14. Naito Y, Takagi T, Handa O, Ishikawa T, Matsumoto N, Yoshida N, Kato H, Ando T, Takemura T, Tani K, Hisatomi H, Tsuchihashi Y, Yoshikawa T: Telomerase activity and expression of telomerase RNA component and catalytic subunits in precancerous and cancerous colorectal lesions. Tumor Biol 22:374-382, 2001
15. Yoshida K, Sugino T, Goodison S, Warren BF, Nolan D, Wadsworth S, Mortensen NJ, Toge T, Tahara E, Tarin D: Detection of telomerase activity in exfoliated cancer cells in colonic luminal washings and its related clinical implications. Br J Cancer 75:548-553, 1997
16. Tang R, Cheng AJ, Wang JY, Wang TC: Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis. Cancer Res 58:4052-4054, 1998
17. Kanamaru T, Tanaka K, Kotani J, Ueno K, Yamamoto M, Idei Y, Hisatomi H, Takeyama Y: Telomerase activity and hTERT mRNA in development and progression of adenoma to colorectal cancer. Int J Mol Med 10:205-210, 2002
18. Holzmann K, Klump B, Weis-Klemm M, Hsieh CJ, Borchard F, Gregor M, Porschen R: Telomerase activity in long-standing ulcerative colitis. Anticancer Res 20:3951-3956, 2000
19. Usselmann B, Newbold M, Morris AG, Nwokolo CU: Deficiency of colonic telomerase in ulcerative colitis. Am J Gastroenterol 96:1106-1112, 2001
20. Hiyama E, Hiyama K, Tatsumoto N, Kodama T, Shay JW, Yokoyama T: Telomerase activity in human intestine. Int J Oncol 9:453-458, 1996
21. Bachor C, Bachor OA, Boukamp P: Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesions. J Cancer Res Clin Oncol 125:453-460, 1999
22. Piatyszek MA, Kim NW, Weinrich SL, Hiyama K, Hiyama E, Wright WE, Shay JW: Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP). Methods Cell Sci 17:1-15, 1995
23. Kleideiter E, Schwab M, Friedrich U, Koscielniak E, Schäfer BW, Klotz U: Telomerase activity in cell lines of pediatric soft tissue sarcomas. Pediatr Res 54:1-6, 2003
24. Abe N, Watanabe T, Nakashima M, Masaki T, Mori T, Sugiyama M, Atomi Y: Quantitative analysis of telomerase activity: a potential diagnostic tool for colorectal carcinoma. Hepato-Gastroenterology 48:692-695, 2001
25. O'Sullivan JN, Bronner MP, Brentnall TA, Finley JC, Shen WT, Emerson S, Emond MJ, Gollahon KA, Moskowitz AH, Crispin DA, Potter JD, Rabinovitch PS: Chromosomal instability in ulcerative colitis is related to telomere shortening. Nature Genet 32:280-284, 2002