Eotaxin and monocyte chemotactic protein-3 use different modes of action

Biochemical and Biophysical Research Communications

Volumn 314, Issue 2, 2004, Pages 646-653

  Chung, Il Yup ^a   Kim, Yong Hyun ^a,b   Choi, Moon Kyung ^a   Noh, Yoon Jung ^a   Park, Choon Sik ^c   Kwon, Do Yoon ^b   Lee, Duck Yeon ^b   Lee, Young Seek ^a   Chang, Hun Soo ^a   Kim, Key Sun ^b  

^a Hanyang University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Department of Internal Medicine   (South Korea)

Author keywords

BIAcore assay; CCR1; CCR2; CCR3; Eosinophils; Eotaxin; MCP 3; Monocytes

Indexed keywords

CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR3; EOTAXIN; MONOCYTE CHEMOTACTIC PROTEIN 3;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CHIMERA; EOSINOPHIL; INTERMETHOD COMPARISON; MONOCYTE; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN MOTIF; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY;

EID: 0347004615     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.12.134     Document Type: Article

References (31)

1. Luster A.D. Chemokines - chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 338:1998;436-445.
2. Zlotnik A., Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity. 12:2000;121-127.
3. Jose P.J., Griffiths-Johnson D.A., Collins P.D., Walsh D.T., Moqbel R., Totty N.F., Truong O., Hsuan J.J., Williams T.J. Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. J. Exp. Med. 179:1994;881-887.
4. Mattoli S., Stacey M.A., Sun G., Bellini A., Marini M. Eotaxin expression and eosinophilic inflammation in asthma. Biochem. Biophys. Res. Commun. 236:1997;299-301.
5. Ying S., Robinson D.S., Meng Q., Rottman J., Kennedy R., Ringler D.J., Mackay C.R., Daugherty B.L., Springer M.S., Durham S.R., Williams T.J., Kay A.B. Enhanced expression of eotaxin and CCR3 mRNA and protein in atopic asthma. Association with airway hyperresponsiveness and predominant co-localization of eotaxin mRNA to bronchial epithelial and endothelial cells. Eur. J. Immunol. 27:1997;3507-3516.
6. Nakamura H., Luster A.D., Nakamura T., In K.H., Sonna L.A., Deykin A., Israel E., Drazen J.M., Lilly C.M. Variant eotaxin: its effects on the asthma phenotype. J. Allergy Clin. Immunol. 108:2001;946-953.
7. Shin H.D., Kim L.H., Park B.L., Jung J.H., Kim J.Y., Chung I.Y., Kim J.S., Lee J.H., Chung S.H., Kim Y.H., Park H.S., Choi J.H., Lee Y.M., Park S.W., Choi B.W., Hong S.J., Park C.S. Association of eotaxin gene family with asthma and serum total IgE. Hum. Mol. Genet. 12:2003;1279-1285.
8. Daugherty B.L., Siciliano S.J., DeMartino J.A., Malkowitz L., Sirotina A., Springer M.S. Cloning, expression, and characterization of the human eosinophil eotaxin receptor. J. Exp. Med. 183:1996;2349-2354.
9. Ponath P.D., Qin S., Post T.W., Wang J., Wu L., Gerard N.P., Newman W., Gerard C., Mackay C.R. Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J. Exp. Med. 183:1996;2437-2448.
10. Sabroe I., Hartnell A., Jopling L.A., Bel S., Ponath P.D., Pease J.E., Collins P.D., Williams T.J. Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways. J. Immunol. 162:1999;2946-2955.
11. Ben-Baruch A., Xu L., Young P.R., Bengali K., Oppenheim J.J., Wang J.M. Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3. J. Biol. Chem. 270:1995;22123-22128.
12. Su S.B., Mukaida N., Wang J., Nomura H., Matsushima K. Preparation of specific polyclonal antibodies to a C-C chemokine receptor, CCR1, and determination of CCR1 expression on various types of leukocytes. J. Leukoc. Biol. 60:1996;658-666.
13. Combadiere C., Ahuja S.K., Van Damme J., Tiffany H.L., Gao J.L., Murphy P.M. Monocyte chemoattractant protein-3 is a functional ligand for CC chemokine receptors 1 and 2B. J. Biol. Chem. 270:1995;29671-29675.
14. Stone M.J., Mayer K.L. Three-dimensional structure of chemokines. Rothenberg M.E. Chemokines in Allergic Disease. 1999;67-94 Marcel Dekker, New York.
15. Ye J., Kohli L.L., Stone M.J. Characterization of binding between the chemokine eotaxin and peptides derived from the chemokine receptor CCR3. J. Biol. Chem. 275:2000;27250-27257.
16. Ye J., Mayer K.L., Mayer M.R., Stone M.J. NMR solution structure and backbone dynamics of the CC chemokine eotaxin-3. Biochemistry. 40:2001;7820-7831.
17. Choi E.N., Choi M.K., Park C.S., Chung I.Y. A parallel signal-transduction pathway for eotaxin- and interleukin-5-induced eosinophil shape change. Immunology. 108:2003;245-256.
18. Fujisawa T., Kato Y., Nagase H., Atsuta J., Terada A., Iguchi K., Kamiya H., Morita Y., Kitaura M., Kawasaki H., Yoshie O., Hirai K. Chemokines induce eosinophil degranulation through CCR-3. J. Allergy Clin. Immunol. 106:2000;507-513.
19. Fagerstam L.G., Frostell-Karlsson A., Karlsson R., Persson B., Ronnberg I. Biospecific interaction analysis using surface plasmon resonance detection applied to kinetic, binding site and concentration analysis. J. Chromatogr. 597:1992;397-410.
20. Crump M.P., Rajarathnam K., Kim K.S., Clark-Lewis I., Sykes B.D. Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation. J. Biol. Chem. 273:1998;22471-22479.
21. Heath H., Qin S., Rao P., Wu L., LaRosa G., Kassam N., Ponath P.D., Mackay C.R. Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody. J. Clin. Invest. 99:1997;178-184.
22. Dahinden C.A., Geiser T., Brunner T., von Tscharner V., Caput D., Ferrara P., Minty A., Baggiolini M. Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine. J. Exp. Med. 179:1994;751-756.
23. Crump M.P., Gong J.H., Loetscher P., Rajarathnam K., Amara A., Arenzana-Seisdedos F., Virelizier J.L., Baggiolini M., Sykes B.D., Clark-Lewis I. Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J. 16:1997;6996-7007.
24. Pease J.E., Wang J., Ponath P.D., Murphy P.M. The N-terminal extracellular segments of the chemokine receptors CCR1 and CCR3 are determinants for MIP-1alpha and eotaxin binding, respectively, but a second domain is essential for efficient receptor activation. J. Biol. Chem. 273:1998;19972-19976.
25. Hemmerich S., Paavola C., Bloom A., Bhakta S., Freedman R., Grunberger D., Krstenansky J., Lee S., McCarley D., Mulkins M., Wong B., Pease J., Mizoue L., Mirzadegan T., Polsky I., Thompson K., Handel T.M., Jarnagin K. Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2. Biochemistry. 38:1999;13013-13025.
26. Wu L., Ruffing N., Shi X., Newman W., Soler D., Mackay C.R., Qin S. Discrete steps in binding and signaling of interleukin-8 with its receptor. J. Biol. Chem. 271:1996;31202-31209.
27. Monteclaro F.S., Charo I.F. The amino-terminal extracellular domain of the MCP-1 receptor, but not the RANTES/MIP-1alpha receptor, confers chemokine selectivity. Evidence for a two-step mechanism for MCP-1 receptor activation. J. Biol. Chem. 271:1996;19084-19092.
28. Siciliano S.J., Rollins T.E., DeMartino J., Konteatis Z., Malkowitz L., Van Riper G., Bondy S., Rosen H., Springer M.S. Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors. Proc. Natl. Acad. Sci. USA. 91:1994;1214-1218.
29. Wells T.N., Power C.A., Lusti-Narasimhan M., Hoogewerf A.J., Cooke R.M., Chung C.W., Peitsch M.C., Proudfoot A.E. Selectivity and antagonism of chemokine receptors. J. Leukoc. Biol. 59:1996;53-60.
30. Martinelli R., Sabroe I., LaRosa G., Williams T.J., Pease J.E. The CC chemokine eotaxin (CCL11) is a partial agonist of CC chemokine receptor 2b. J. Biol. Chem. 276:2001;42957-42964.
31. Mayer K.L., Stone M.J. NMR solution structure and receptor peptide binding of the CC chemokine eotaxin-2. Biochemistry. 39:2000;8382-8395.