Utilization of an HSV-based amplicon vector encoding the axonal marker hPLAP to follow neurite outgrowth in cultured DRG neurons

Journal of Neuroscience Methods

Volumn 132, Issue 2, 2004, Pages 169-176

  Seijffers, Rhona ^a   Woolf, Clifford J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Bicistronic expression; Dorsal root ganglion neurons; Enhanced green fluorescent protein; Gene delivery; Growth associated protein 43; Herpes simplex virus; Human placental alkaline phosphatase

Indexed keywords

ALKALINE PHOSPHATASE PLACENTA ISOENZYME; BIOLOGICAL MARKER; HERPESVIRUS VECTOR; NEUROMODULIN;

AMPLICON; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; GENE CASSETTE; GENE EXPRESSION; GENE TRANSFER; INTERNAL RIBOSOME ENTRY SITE; MOLECULAR CLONING; NERVE FIBER GROWTH; NEURITE; NONHUMAN; PRIORITY JOURNAL; RAT; REPORTER GENE; RNA TRANSLATION; SPINAL GANGLION;

EID: 0346997978     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2003.09.027     Document Type: Article

References (35)

1. Aigner L., Caroni P. Depletion of 43-kD growth-associated protein in primary sensory neurons leads to diminished formation and spreading of growth cones. J. Cell. Biol. 123:1993;417-429.
2. Aigner L., Arber S., Kapfhammer J.P., Laux T., Schneider C., Botteri F., Brenner H.R., Caroni P. Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice. Cell. 83:1995;269-278.
3. Bao Z.Z., Cepko C.L. The expression and function of Notch pathway genes in the developing rat eye. J. Neurosci. 17:1997;1425-1434.
4. Basi G.S., Jacobson R.D., Virag I., Schilling J., Skene J.H. Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth. Cell. 49:1987;785-791.
5. Benn S.C., Perrelet D., Kato A.C., Scholz J., Decosterd I., Mannion R.J., Bakowska J.C., Woolf C.J. Hsp27 upregulation and phosphorylation is required for injured sensory and motor neuron survival. Neuron. 36:2002;45-56.
6. Bomze H.M., Bulsara K.R., Iskandar B.J., Caroni P., Skene J.H. Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons. Nat. Neurosci. 4:2001;38-43.
7. Cai L., Morrow E.M., Cepko C.L. Misexpression of basic helix-loop-helix genes in the murine cerebral cortex affects cell fate choices and neuronal survival. Development. 127:2000;3021-3030.
8. Caroni P. Intrinsic neuronal determinants that promote axonal sprouting and elongation. Bioessays. 19:1997;767-775.
9. Costantini L.C., Bakowska J.C., Breakefield X.O., Isacson O. Gene therapy in the CNS. Gene. Ther. 7:2000;93-109.
10. Dickson B.J. Molecular mechanisms of axon guidance. Science. 298:2002;1959-1964.
11. Fields-Berry S.C., Halliday A.L., Cepko C.L. A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina. Proc. Natl. Acad. Sci. U.S.A. 89:1992;693-697.
12. Franceschini I.A., Feigenbaum-Lacombe V., Casanova P., Lopez-Lastra M., Darlix J.L., Dalcq M.D. Efficient gene transfer in mouse neural precursors with a bicistronic retroviral vector. J. Neurosci. Res. 65:2001;208-219.
13. Gustincich S., Feigenspan A., Wu D.K., Koopman L.J., Raviola E. Control of dopamine release in the retina: a transgenic approach to neural networks. Neuron. 18:1997;723-736.
14. Hermens W.T., Verhaagen J. Viral vectors, tools for gene transfer in the nervous system. Prog. Neurobiol. 55:1998;399-432.
15. Hermens W.T., Giger R.J., Holtmaat A.J., Dijkhuizen P.A., Houweling D.A., Verhaagen J. Transient gene transfer to neurons and glia: analysis of adenoviral vector performance in the CNS and PNS. J. Neurosci. Methods. 71:1997;85-98.
16. Leighton P.A., Mitchell K.J., Goodrich L.V., Lu X., Pinson K., Scherz P., Skarnes W.C., Tessier-Lavigne M. Defining brain wiring patterns and mechanisms through gene trapping in mice. Nature. 410:2001;174-179.
17. Moss D.J., Fernyhough P., Chapman K., Baizer L., Bray D., Allsopp T. Chicken growth-associated protein GAP-43 is tightly bound to the actin-rich neuronal membrane skeleton. J. Neurochem. 54:1990;729-736.
18. Neumann S., Woolf C.J. Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury. Neuron. 23:1999;83-91.
19. Oestreicher A.B., De Graan P.N., Gispen W.H., Verhaagen J., Schrama L.H. B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system. Prog. Neurobiol. 53:1997;627-686.
20. Olschowka J.A., Bowers W.J., Hurley S.D., Mastrangelo M.A., Federoff H.J. Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS. Mol. Ther. 7:2003;218-227.
21. Saeki Y., Ichikawa T., Saeki A., Chiocca E.A., Tobler K., Ackermann M., Breakefield X.O., Fraefel C. Herpes simplex virus type 1 DNA amplified as bacterial artificial chromosome in Escherichia coli: rescue of replication-competent virus progeny and packaging of amplicon vectors. Hum. Gene. Ther. 9:1998;2787-2794.
22. Saeki Y., Fraefel C., Ichikawa T., Breakefield X.O., Chiocca E.A. Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome. Mol. Ther. 3:2001;591-601.
23. Sandler V.M., Wang S., Angelo K., Lo H.G., Breakefield X.O., Clapham D.E. Modified herpes simplex virus delivery of enhanced GFP into the central nervous system. J. Neurosci. Methods. 121:2002;211-219.
24. Schwab M.E. Repairing the injured spinal cord. Science. 295:2002;1029-1031.
25. Schwab M.E., Bartholdi D. Degeneration and regeneration of axons in the lesioned spinal cord. Physiol. Rev. 76:1996;319-370.
26. Sena-Esteves M., Saeki Y., Fraefel C., Breakefield X.O. HSV-1 amplicon vectors - simplicity and versatility. Mol. Ther. 2:2000;9-15.
27. Simonato M., Manservigi R., Marconi P., Glorioso J. Gene transfer into neurones for the molecular analysis of behaviour: focus on herpes simplex vectors. Trends Neurosci. 23:2000;183-190.
28. Skene J.H. Axonal growth-associated proteins. Annu. Rev. Neurosci. 12:1989;127-156.
29. Smith D.S., Skene J.H. A transcription-dependent switch controls competence of adult neurons for distinct modes of axon growth. J. Neurosci. 17:1997;646-658.
30. Snider W.D., Zhou F.Q., Zhong J., Markus A. Signaling the pathway to regeneration. Neuron. 35:2002;13-16.
31. Spergel D.J., Kruth U., Shimshek D.R., Sprengel R., Seeburg P.H. Using reporter genes to label selected neuronal populations in transgenic mice for gene promoter, anatomical, and physiological studies. Prog. Neurobiol. 63:2001;673-686.
32. Strittmatter S.M., Fankhauser C., Huang P.L., Mashimo H., Fishman M.C. Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell. 80:1995;445-452.
33. Tandrup T., Woolf C.J., Coggeshall R.E. Delayed loss of small dorsal root ganglion cells after transection of the rat sciatic nerve. J. Comp. Neurol. 422:2000;172-180.
34. Tessier-Lavigne M., Goodman C.S. The molecular biology of axon guidance. Science. 274:1996;1123-1133.
35. Wiederkehr A., Staple J., Caroni P. The motility-associated proteins GAP-43, MARCKS, and CAP-23 share unique targeting and surface activity-inducing properties. Exp. Cell. Res. 236:1997;103-116.