Generation of Bis-Cationic Heterocyclic Inhibitors of Bacillus subtilis HPr Kinase/Phosphatase from a Ditopic Dynamic Combinatorial Library

Journal of Medicinal Chemistry

Volumn 46, Issue 26, 2003, Pages 5803-5811

  Bunyapaiboonsri, Taridaporn ^a   Ramström, Helena ^b   Ramström, Olof ^a   Haiech, Jacques ^b   Lehn, Jean Marie ^a  

^a UNIVERSITÉ LOUIS PASTEUR   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOBENZIMIDAZOLE; ALDEHYDE; BACTERIAL ENZYME; BENZIMIDAZOLE DERIVATIVE; HPR KINASE; HPR PHOSPHATASE; HYDRAZIDE; HYDRAZONE DERIVATIVE; PHOSPHOTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; COMBINATORIAL LIBRARY; DRUG SCREENING; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; MOLECULAR RECOGNITION; PROTEIN TARGETING;

ALDEHYDES; BACTERIAL PROTEINS; BENZIMIDAZOLES; COMBINATORIAL CHEMISTRY TECHNIQUES; HYDRAZINES; PHOSPHOENOLPYRUVATE SUGAR PHOSPHOTRANSFERASE SYSTEM; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0346996358     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030917j     Document Type: Article

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