Nonspecific protease-catalyzed hydrolysis/synthesis of a mixture of peptides: Product diversity and ligand amplification by a molecular trap

Biopolymers

Volumn 40, Issue 6, 1996, Pages 617-625

  Swann, Patrick A ^a,d   Casanova, Rose A ^a,e   Desai, Archana ^a,b,f   Frauenhoff, Mary M ^a   Urbancic, Minka ^a   Slomczynska, Urszulo ^a,g   Hopfinger, Anton J ^b   Le Breton, Guy C ^c   Venton, Duane L ^b  

^a Receptor Laboratories   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF ILLINOIS   (United States)

^d NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

^f Midwest em University   (United States)

^g NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Ligand amplification; Molecular trap; Nonspecific protease catalyzed hydrolysis synthesis; Peptide library; Product diversity

Indexed keywords

PEPTIDE DERIVATIVE; PROTEIN HYDROLYSATE; PROTEINASE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; ENZYME SUBSTRATE; HYDROLYSIS; PEPTIDE SYNTHESIS; PROTEIN DEGRADATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENDOPEPTIDASES; FIBRINOGEN; HYDROLYSIS; LIGANDS; PEPTIDES; PROTEIN BINDING;

EID: 0030441086     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0282(1996)40:6<617::AID-BIP3>3.0.CO;2-Z     Document Type: Article

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