Relationship between expression of CD105 and growth factors in malignant tumors of gastrointestinal and its significance

World Journal of Gastroenterology

Volumn 9, Issue 12, 2003, Pages 2866-2869

  Yu, Jian Xian ^a   Zhang, Xiao Tun ^a   Liao, Yong Qiang ^b   Zhang, Qi Yi ^a   Chen, Hua ^a   Lin, Mei ^c   Kumar, Shant ^c  

^a QINGDAO MUNICIPAL HOSPITAL   (China)

^b Xiamen People's Hospital   (China)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; ENDOGLIN; ENG PROTEIN, HUMAN; GROWTH FACTOR; LEUKOCYTE ANTIGEN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; VASCULOTROPIN A;

ADENOCARCINOMA; ADULT; AGED; ANGIOGENESIS; ARTICLE; BLOOD VESSEL; CANCER GRADING; CANCER INVASION; CANCER STAGING; CANCER TISSUE; CLINICAL TRIAL; COLON CARCINOMA; COLON TUMOR; COLORECTAL CARCINOMA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DENSITY; DIGESTIVE SYSTEM CANCER; DISEASE ASSOCIATION; GENETICS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MICROCIRCULATION; MICROVASCULATURE; MULTICENTER STUDY; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STATISTICAL ANALYSIS; STOMACH CANCER; STOMACH CARCINOMA; STOMACH TUMOR; VASCULARIZATION;

EID: 0346967077     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v9.i12.2866     Document Type: Article

References (16)

1. Griffioen AW, Molema G. Angiogenesis: Potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation. Pharmacol Rev 2000; 52: 237-268
2. De Jong JS, Van Diest PJ, Van Der Valk P, Baak JP. Expression of growth factors, growth-inhibiting factors, and their receptors in invasive breast cancer. II: Correlations with proliferation and angiogenesis. J Pathol 1998; 184: 53-57
3. Hasegawa Y, Takanashi S, Kanehira Y, Tsushima T, Imai T, Okumura K. Transforming growth factor-beta1 level correlates with angiogenesis, tumor progression, and prognosis in patients with nonsmall cell lung carcinoma. Cancer 2001; 91: 964-971
4. Maehara Y, Kakeji Y, Kabashima A, Emi Y, Watanabe A, Akazawa K, Baba H, Kohnoe S, Sugimachi K. Role of transforming growth factor-beta 1 in invasion and metastasis in gastric carcinoma. J Clin Oncol 1999; 17: 607-614
5. Xiong B, Gong LL, Zhang F, Hu MB, Yuan HY. TGF beta1 expression and angiogenesis in colorectal cancer tissue. World J Gastroenterol 2002; 8: 496-498
6. Li C, Hampson IN, Hampson L, Kumar P, Bernabeu C, Kumar S. CD105 antagonizes the inhibitory signaling of transforming growth factor beta1 on human vascular endothelial cells. FASEB J 2000; 14: 55-64
7. Calabro L, Fonsatti E, Bellomo G, Alonci A, Colizzi F, Sigalotti L, Altomonte M, Musolino C, Maio M. Differential levels of soluble endoglin (CD105) in myeloid malignancies. J Cell Physiol 2003; 194: 171-175
8. Kaio E, Tanaka S, Kitadai Y, Sumii M, Yoshihara M, Haruma K, Chayama K. Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma. Oncology 2003; 64: 61-73
9. Song ZJ, Gong P, Wu YE. Relationship between the expression of iNOS, VEGF, tumor angiogenesis and gastric cancer. World J Gastroenterol 2002; 8: 591-595
10. Li HJ, Jing J, Zhao YB, Zhu JQ, Zhang SY, Shi ZD. Tumor angiogenesis in node-negative breast carcinoma. Ai Zheng 2002; 21: 75-78
11. Sauter ER, Nesbit M, Watson JC, Klein-Szanto A, Litwin S, Herlyn M. Vascular endothelial growth factor is a marker of tumor invasion and metastasis in squamous cell carcinomas of the head and neck. Clin Cancer Res 1999; 5: 775-782
12. Emoto M, Iwasaki H, Mimura K, Kawarabayashi T, Kikuchi M. Difference in the angiogenesis of benign and malignant ovarian tumors, demonstrated by analyses of solor Doppler ultrasound, immunohistochemistry, and microvessel density. Cancer 1997; 80: 899-907
13. Fonsatti E, Del Vecchio L, Altomonte M, Sigalotti L, Nicotra MR, Coral S, Natali PG, Maio M. Endoglin: An accessory component of the TGF-β-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies. J Cell Physiol 2001; 188: 1-7
14. Miller DW, Graulich W, Karges B, Stahl S, Ernst M, Ramaswamy A, Sedlacek HH, Muller R, Adamkiewicz J. Elevated expression of endoglin, a component of the TGF-beta-receptor complex, correlates with proliferation of tumor endothelial cells. Int J Cancer 1999; 81: 568-572
15. Bodey B, Bodey B Jr., Siegel SE, Kaiser HE. Over-expression of endoglin (CD105): A marker of breast carcinoma-induced neovascularization. Anticancer Res 1998; 18: 3621-3628
16. Kumar S, Ghellal A, Li C, Byrne G, Haboubi N, Wang JM, Bundred N. Breast carcinoma: Vascular density determined using CD105 antibody correlates with tumor prognosis. Cancer Res 1999; 59: 856-861