Structure-function analysis of the self-recognizing Antigen 43 autotransporter protein from Escherichia coli

Molecular Microbiology

Volumn 51, Issue 1, 2004, Pages 283-296

  Klemm, Per ^a   Hjerrild, Louise ^a   Gjermansen, Morten ^a   Schembri, Mark A ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; ANTIGEN 43; BACTERIAL PROTEIN; UNCLASSIFIED DRUG;

ANTIGEN RECOGNITION; BACTERIUM ADHERENCE; BIOFILM; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; IMMUNOBLOTTING; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SHORT SURVEY;

ADHESINS, BACTERIAL; AMINO ACID SEQUENCE; ANTIGENS, BACTERIAL; ARABINOSE; BACTERIAL OUTER MEMBRANE PROTEINS; BASE SEQUENCE; BINDING SITES; BIOLOGICAL TRANSPORT; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENOTYPE; KINETICS; MOLECULAR SEQUENCE DATA; PHENOTYPE; PROTEIN STRUCTURE, SECONDARY; RESTRICTION MAPPING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; VARIATION (GENETICS);

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0346964245     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2003.03833.x     Document Type: Short Survey

References (53)

1. Anderson, G.G., Palermo, J.J., Schilling, J.D., Roth, R., Heuser, J., and Hultgren, S.J. (2003) Intracellular bacterial biofilm-like pods in urinary tract infections. Science 301: 105-107.
2. Bachmann, B. (1996) Derivations and genotypes of some mutant derivatives of Escherichia coli K-12. In Escherichia Coli and Salmonella: Cellular and Molecular Biology, 2nd edn. Neidhardt, F.C., Curtis, R., Ingraham, J.L., III, Lin, E.C., Low, K.B., and Magasanik, B. (eds). Washington, D.C.: American Society for Microbiology Press, pp. 2460-2488.
3. Benz, I., and Schmidt, M.A. (1989) Cloning and expression of an adhesin (AIDA-I) involved in diffuse adherence of enteropathogenic Escherichia coli. Infect Immun 57:1506-1511.
4. Berge, A., Kihlberg, B.-M., Sjöholm, A.G., and Björck, L. (1997) Streptococcal protein H forms soluble complement activating complexes with IgG, but inhibits complement activation by IgG-coated targets. J Biol Chem 272:20774-20774.
5. Bieber, D., Ramer, S.W., Wu, C.-Y., Murray, W.J., Tobe, T., Fernandez, R., and Schoolnik, G.K. (1998) Type IV pili, transient bacterial aggregates, and virulence of enteropathogenic Escherichia coli. Science 280: 2114-2118.
6. Czeczulin, J.R., Balepur, S., Hicks, S., Phillips, A., Hall, R., Mahendra, M.H., et al. (1997) Aggregative adherence fimbria II, a second fimbrial antigen mediating aggregative adherence in enteroaggregative Escherichia coli. Infect Immun 65: 4135-4145.
7. Danese, P.N., Pratt, L.A., Dove, S.L., and Kolter, R. (2000) The outer membrane protein, Antigen 43, mediates cell-to-cell interactions within Escherichia coli biofilms. Mol Microbiol 37: 424-432.
8. Diderichsen, B. (1980) flu, a metastable gene controlling surface properties of Escherichia coli. J Bacteriol 141: 858-867.
9. Emsley, P., Charles, I.G., Fairweather, N.F., and Isaacs, N.W. (1996) Structure of Bordetella pertussis virulence factor P. 69 pertactin. Nature 381: 90-92.
10. Force, A., Lynch, M., Picket, F.B., Amores, A., Yan, Y.L., and Postlewait, J. (1999) Preservation of duplicate genes by complementary, degenerative mutations. Genetics 151: 1531-1545.
11. Frick, I.-M., Mörgelin, M., and Björck, L. (2000) Virulent aggregates of Streptococcus pyogenes are generated by homophilic protein-protein interactions. Mol Microbiol 37: 1232-1247.
12. Giron, J.A., Ho, A.S., and Schoolnik, G.K. (1991) An inducible bundle-forming pilus of enteropathogenic Escherichia coli. Science 254: 710-713.
13. Guzman, L.M., Belin, D., Carson, M.J., and Beckwith, J. (1995) Tight regulation, modulation, and high-level expression by vectors containing the arabinose pBAD promoter. J Bacteriol 177: 4121-4130.
14. Haagmans, W., and van der Woude, M. (2000) Phase variation of Ag43 in Escherichia coli: Dam-dependent methylation abrogates OxyR binding and OxyR-mediated repression of transcription. Mol Microbiol 35: 877-887.
15. Hammar, M., Bian, Z., and Normark, S. (1996) Nucleator dependent intercellular assembly of adhesive curli organelles in Escherichia coli. Proc Natl Acad Sci USA 93: 6562-6566.
16. Hasman, H., Chakraborty, T., and Klemm, P. (1999) Antigen-43-mediated autoaggregation of Escherichia coli is blocked by fimbriation. J Bacteriol 182: 1089-1095.
17. Hasman, H., Schembri, M.A., and Klemm, P. (2000) Antigen 43 and type 1 fimbriae determine colony morphology of Escherichia coli K-12. J Bacteriol 182: 1089-1095.
18. Henderson, I.R., and Owen, P. (1999) The major phase-variable outer membrane protein of Escherichia coli structurally resembles the immunoglobulin A1 protease class of exported protein and is regulated by a novel mechanism involving Dam and oxyR. J Bacteriol 181: 2132-2141.
19. Henderson, I.R., and Nataro, J.P. (2001) Virulence functions of autotransporter proteins. Infect Immun 69: 1231-1243.
20. Henderson, I.R., Owen, P., and Nataro, J.P. (1999) Molecular switches - the ON and OFF of bacterial phase variation. Mol Microbiol 33: 919-932.
21. Hull, R.A., Gill, R.E., Hsu, P., Minshew, B.H., and Falkow, S. (1981) Construction and expression of recombinant plasmids encoding type 1 or D-mannose-resistant pili from a urinary tract infection Escherichia coli isolate. Infect Immun 33: 933-938.
22. Jenkins, J., and Pickersgill, R. (2001) The architecture of parallel beta-helixes and related folds. Prog Biophys Mol Biol 77: 111-175.
23. Kajava, A.V., Cheng, N., Cleaver, R., Kessel, M., Simon, M.N., Willery, E., et al. (2001) Beta-helix model for the filamentous haemagglutinin adhesin of Bordetella pertussis and related bacterial secretory proteins. Mol Microbiol 42: 279-292.
24. Kjærgaard, K., Schembri, M.A., Hasman, H., and Klemm, P. (2000a) Antigen 43 from Escherichia coli induces interand intraspecies cell aggregation and changes in colony morphology of Pseudomonas fluorescens. J Bacteriol 182: 4789-4796.
25. Kjærgaard, K., Schembri, M.A., Ramos, C., Molin, S., and Klemm, P. (2000b) Antigen 43 facilitates formation of multispecies biofilms. Environ Microbiol 2: 695-702.
26. Kjærgaard, K., Hasman, H., Schembri, M.A., and Klemm, P. (2002) Antigen 43-mediated autotransporter display, a versatile bacterial cell surface presentation system. J Bacteriol 184: 4197-4204.
27. Klemm, P., and Schembri, M.A. (2000) Bacterial adhesins: structure and function. Int J Med Microbiol 290: 27-35.
28. Low, D.A., Weyand, N.J., and Mahan, M.J. (2001) Roles of DNA adenine methylation in regulating bacterial gene expression and virulence. Infect Immun 69: 7197-7204.
29. McDevitt, D., Francois, P., Vaudaux, P., and Foster, T.J. (1994) Molecular characterization of the clumping factor (fibronectin receptor) of Staphylococcus aureus. Mol Microbiol 11: 237-248.
30. Menozzi, F.D., Boucher, P.E., Riveau, G., Gantiez, C., and Locht, C. (1994) Surface associated filamentous hemagglutinin induces autoagglutination of Bordetella pertussis. Infect Immun 62: 4261-4269.
31. Menozzi, F.D., Rouse, J.H., Alawi, M., Laude-Sharp, M., Muller, J., Bischoff, R., et al. (1996) Identification of a heparin-binding hemagglutinin present in mycobacteria. J Expt Immun 184: 993-1001.
32. Mobley, H.L., Green, D.M., Trifillis, A.L., Johnson, D.E., Chippendale, G.R., Lockatell, C.V., et al. (1990) Pyelonephritogenic Escherichia coli and killing of cultured human renal proximal tubular epithelial cells: role of hemolysin in some strains. Infect Immun 58: 1281-1289.
33. Nataro, J.P., and Kaper, J.B. (1998) Diarrheagenic Escherichia coli. Clin Microbiol Rev 11: 142-201.
34. Nataro, J.P., Kaper, J.B., Robins-Browne, R., Prado, V., Vial, P., and Levine, M.M. (1987) Patterns of adherence of diarrheagenic Escherichia coli. Pediatr Infect Dis J 6:829-831.
35. Nataro, J.P., Deng, Y., Maneval, D.R., German, A.L., Martin, W.C., and Levine, M.M. (1992) Aggregative adherence fimbriae I of enteroaggregative Escherichia coli mediate adherence to HEp-2 cells and hemagglutination of human erythrocytes. Infect Immun 60: 2297-2304.
36. Ochiai, K., Kurita-Ochiai, T., Kamino, Y., and Ikeda, T. (1993) Effect of co-aggregation on the pathogenicity of oral bacteria. J Med Microbiol 39: 183-190.
37. Owen, P. (1983) Antigens of the Escherichia coli cell envelope. In Electroimmununochemical Analysis of Membrane Proteins. Bjerrum, O.J. (ed.). Amsterdam: Elsevier Science Publishing, Inc., pp. 347-373.
38. Owen, P. (1992) The gram-negative outer membrane: structure, biochemistry and vaccine potential. Biochem Soc Trans 20: 1-6.
39. Owen, P., Meehan, M., de Loughry-Doherty, H., and Henderson, I. (1996) Phase-variable outer membrane proteins in Escherichia coli. FEMS Immunol Med Microbiol 16: 63-76.
40. Roche, A.J., McFadden, J.P., and Owen, P. (2001) Antigen 43, the major phase-variable protein of the Escherichia coli outer membrane, can exist as a family of proteins encoded by multiple alleles. Microbiology 147: 161-169.
41. Schembri, M.A., and Klemm, P. (2001a) Coordinate gene regulation by fimbriae-induced signal transduction. EMBO J 20: 3074-3081.
42. Schembri, M.A., and Klemm, P. (2001b) Biofilm formation in a hydrodynamic environment by novel FimH variants and ramifications for virulence. Infect Immun 69: 1322-1328.
43. Schembri, M.A., Christiansen, G., and Klemm, P. (2001) FimH-mediated autoaggregation of Escherichia coli. Mol Microbiol 41: 1419-1430.
44. Schembri, M.A., Givskov, M., and Klemm, P. (2002a) An attractive surface: Gram-negative bacterial biofilms. Science STKE 132: RE6.
45. Schembri, M.A., Ussery, D.W., Workman, C., Hasman, H., and Klemm, P. (2002b) DNA microarray analysis of fim mutations in Escherichia coli. Mol Genet Genom 267: 721-729.
46. Schembri, M.A., Hjerrild, L., Gjermansen, M., and Klemm, P. (2003a) Differential expression of the Escherichia coli autoaggregation factor Antigen 43. J Bacteriol 185: 2236-2242.
47. Schembri, M.A., Kjærgaard, K., and Klemm, P. (2003b) Global gene expression in Escherichia coli biofilms. Mol Microbiol 48: 253-267.
48. Silver, R.P., Aaronson, W., Sutton, A., and Schneerson, R. (1980) Comparative analysis of plasmids and some metabolic characteristics of Escherichia coli K1 from diseased and healthy individuals. Infect Immun 29: 200-206.
49. Stentebjerg-Olesen, B., Pallesen, L., Jensen, L.B., Christiansen, G., and Klemm, P. (1997) Authentic display of a cholera toxin epitope by chimeric type 1 fimbriae: effects of insert position and host background. Microbiology 143: 2027-2038.
50. Sutcliffe, J.G. (1978) Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322. Proc Natl Acad Sci USA 75: 3737-3741.
51. Torres, A.G., Perna, N.T., Burland, V., Ruknudin, A., Blattner, F.R., and Kaper, J.B. (2002) Characterization of Cah, a calcium-binding and heatextractable autotransporter of enterohaemorrhagic E. coli. Mol Microbiol 45: 951-966.
52. Warne, S.R., Varley, J.M., Boulnois, G.J., and Norton, M.G. (1990) Identification and characterization of a gene that controls colony morphology and auto-aggregation in Escherichia coli K12. J General Microbiol 136: 455-462.
53. Wells, J.G., Davis, B.R., Wachsmuth, I.K., Riley, L.W., Remis, R.S., Sokolow, R., and Morris, G.K. (1983) Laboratory investigation of hemorrhagic colitis outbreaks associated with a rare Escherichia coli serotype. J Clin Microbiol 18: 512-520.