An efficient synthesis of N3,4-diphenyl-5-(4-fluorophenyl)-2-isopropyl-1H- 3-pyrrolecarboxamide, a key intermediate for atorvastatin synthesis

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 1, 2004, Pages 129-131

  Pandey, Pramod S ^a   Rao, T Srinivasa ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

Author keywords

1,3 Dipolar cycloaddition; 1,3 Oxazolium 5 olate; Atorvastatin; Munchnone; N Debenzylation

Indexed keywords

1,3 OXAZOLIUM 5 OLATE; AMIDE; AMMONIA; AMPHOLYTE; ATORVASTATIN; BENZENE DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; N BENZYLPYRROLE; N1,3 DIPHENYL 2 PROPYNAMIDE; N3,4 DIPHENYL 5 (4 FLUOROPHENYL) 2 ISOPROPYL 1H 3 PYRROLECARBOXAMIDE; OXAZOLE DERIVATIVE; PYRROLE DERIVATIVE; SODIUM; UNCLASSIFIED DRUG;

ARTICLE; BENZYLATION; CYCLOADDITION; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 0346887167     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.10.019     Document Type: Article

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12. 3) δ 166, 164, 161, 143, 138.33, 134.55, 132.93, 130.54, 128.72, 128.39, 127.31, 126.61, 125.48, 123.57, 119.61, 115.31, 115.03, 48.03, 26.65, 21.38.
13. 3) δ 168.67, 165.73, 163.52, 145.3, 144.6, 137.9, 132.19, 131.29, 129.20, 128.64, 127.87, 126.70, 124.65, 123.20, 121.29, 119.13, 118.52, 116.50, 25.95, 22.27.