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Volumn 43, Issue 11, 2002, Pages 2087-2090

An improved synthesis of 1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate, a key intermediate for atorvastatin synthesis

(3) Rαdl, Stanislav a Stach, Jan a Hajicek, Josef a

a Research Institute of Pharmacy and Biochemistry Prague (Czech Republic)

Author keywords

Atorvastatin intermediate; Iodolactonization; Stereocontrolled synthesis

Indexed keywords

(2,2 DIMETHYL 6 OXIRANYLMETHYL 1,3 DIOXAN 4 YL)ACETONITRILE; (6 ALLYL 2,2 DIMETHYL 1,3 DIOXAN 4 YL)ACETONITRILE; (6 CYANOMETHYL 2,2 DIMETHYL 1,3 DIOXAN 4 YL)ACETIC ACID; 4 ALLYL 6 IODOMETHYL 1,3 DIOXAN 2 ONE; 6 CYANOMETHYL 2,2 DIMETHYL 1,3 DIOXANE 4 ACETATE; ACETIC ACID DERIVATIVE; ACETONITRILE DERIVATIVE; ALDEHYDE; ATORVASTATIN; DIOXANE DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LACTONE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; SYNTHESIS;

EID: 0037060950 PISSN: 00404039 EISSN: None Source Type: Journal
DOI: 10.1016/S0040-4039(02)00175-2 Document Type: Article

Times cited : (29)

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