Transcription of TIM9, a new factor required for the petite-positive phenotype of Saccharomyces cerevisiae, is defective in spt7 mutants

Current Genetics

Volumn 44, Issue 4, 2003, Pages 202-210

  Senapin, Saengchan ^a   Chen, Xin Jie ^b   Clark Walker, G Desmond ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Mitochondria; Petite phenotype; Protein import; Transcription factor

Indexed keywords

ARGININE; CARRIER PROTEIN; GLYCINE; MITOCHONDRIAL DNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SPT7; TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 9; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; BACTERIAL STRAIN; CELL VIABILITY; CODING; CODON; GENE MUTATION; LETHALITY; MUTANT; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PLASMID; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; SACCHAROMYCES CEREVISIAE; SURVIVAL; TEMPERATURE; TRANSCRIPTION REGULATION;

ALLELES; AMINO ACID SEQUENCE; BLOTTING, NORTHERN; DNA MUTATIONAL ANALYSIS; DNA PRIMERS; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHENOTYPE; POINT MUTATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ANALYSIS, DNA; TEMPERATURE; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

SACCHAROMYCES CEREVISIAE;

EID: 0346882887     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00294-003-0437-9     Document Type: Article

References (42)

1. 1-ATPase. Proc Natl Acad Sci USA 87:4986-4990
2. Adam A, Endres M, Sirrenberg C, Lottspeich F, Neupert W, Brunner M (1999) Tim9, a new component of the TIM22.54 translocase in mitochondria. EMBO J 18:313-319
3. Burke D, Dawson D, Stearns T (2000) Methods in Yeast Genetics: A Cold Spring Harbor Laboratory Course Manual 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
4. Chang SC, Heacock PN, Clancey CJ, Dowhan W (1998) The PEL1 gene (renamed PGS1) encodes the phosphatidylglycerophosphate synthase of Saccharomyces cerevisiae. J Biol Chem 273:9829-9836
5. Chen XJ, Clark-Walker GD (1993) Mutations in MGI genes convert Kluyveromyces lactis into a petite-positive yeast. Genetics 133:517-525
6. 1-ATPase affect mitochondrial genome integrity in the petite-negative yeast Kluyveromyces lactis. EMBO J 14:3277-3286
7. 1-ATPase. Genetics 144:1445-1454
8. 1-ATPase are required for survival of petite mutants in Saccharomyces cerevisiae. Mol Gen Genet 262:898-908
9. Chen XJ, Clark-Walker GD (2000) The petite mutation in yeasts: 50 years on. Int Rev Cytol 194:197-238
10. Chen X, Fukuhara H (1988) A gene fusion system using the aminoglycoside 3′-phosphotransferase gene of the kanamycin-resistance transposon Tn903: Use in the yeast Kluyveromyces lactis and Saccharomyces cerevisiae. Gene 69:181-192
11. Contamine V, Picard M (2000) Maintenance and integrity of the mitochondrial genome: A plethora of nuclear genes in the budding yeast. Microbiol Mol Biol Rev 64:281-315
12. Curran SP, Leuenberger D, Oppliger W, Koehler CM (2002) The Tim9p-Tim10p complex binds to the transmembrane domains of the ADP/ATP carrier. EMBO J 21:942-953
13. Davis AJ, Sepuri NB, Holder J, Johnson AE, Jensen RE (2000) Two intermembrane space TIM complexes interact with different domains of Tim23p during its import into mitochondria. J Cell Biol 150:1271-1282
14. Dujon B (1981) Mitochondrial Genetics and Functions. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
15. Ephrussi B (1953) Nucleocytoplasmic Relations in Micro-Organisms: Their Bearing on Cell Heredity and Differentiation. Clarendon Press, Oxford
16. Ephrussi B, Hottinguer H, Chimenes A-M (1949) Action de l'acriflavin sur les levures. I. La mutation 'petite colonie'. Ann Inst Pasteur 76:419-450
17. Gansheroff LJ, Dollard C, Tan P, Winston F (1995) The Saccharomyces cerevisiae SPT7 gene encodes a very acidic protein important for transcription in vivo. Genetics 139:523-536
18. Gietz RD, Schiestl RH, Willems AR, Woods RA (1995) Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure. Yeast 11:355-360
19. Janitor M, Subik J (1993) Molecular cloning of the PEL1 gene of Saccharomyces cerevisiae that is essential for the viability of petite mutants. Curr Genet 24:307-312
20. Jarosch E, Tuller G, Daum G, Waldherr M, Voskova A, Schweyen RJ (1996) Mrs5p, an essential protein of the mitochondrial intermembrane space, affects protein import into yeast mitochondria. J Biol Chem 271:17219-17225
21. Jarosch E, Rodel G, Schweyen RJ (1997) A soluble 12-kDa protein of the mitochondrial intermembrane space, Mrs11p, is essential for mitochondrial biogenesis and viability of yeast cells. Mol Gen Genet 255:157-165
22. Kerscher O, Holder J, Srinivasan M, Leung RS, Jensen RE (1997) The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane. J Cell Biol 139:1663-1675
23. Kerscher O, Sepuri NB, Jensen RE (2000) Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane. Mol Biol Cell 11:103-116
24. Koehler CM, Jarosch E, Tokatlidis K, Schmid K, Schweyen RJ, Schatz G (1998a) Import of mitochondrial carriers mediated by essential proteins of the intermembrane space. Science 279:369-373
25. Koehler CM, Merchant S, Oppliger W, Schmid K, Jarosch E, Dolfini L, Junne T, Schatz G, Tokatlidis K (1998b) Tim9p, an essential partner subunit of Tim10p for the import of mitochondrial carrier proteins. EMBO J 17:6477-6486
26. Koehler CM, Leuenberger D, Merchant S, Renold A, Junne T, Schatz G (1999) Human deafness dystonia syndrome is a mitochondrial disease. Proc Natl Acad Sci USA 96:2141-2146
27. Koehler CM, Murphy MP, Bally NA, Leuenberger D, Oppliger W, Dolfini L, Junne T, Schatz G, Or E (2000) Tim18p, a new subunit of the TIM22 complex that mediates insertion of imported proteins into the yeast mitochondrial inner membrane. Mol Cell Biol 20:1187-1193
28. Kovacova, Irmlerova J, Kovac L (1968) Oxidative phosphorylation in yeast. IV. Combination of a nuclear mutation affecting oxidative phosphorylation with cytoplasmic mutation to respiratory deficiency. Biochim Biophys Acta 162:157-163
29. 1-ATPase in heat stress conditions. J Biol Chem 276:6789-6796
30. Leuenberger D, Curran SP, Wong D, Koehler CM (2003) The role of Tim9p in the assembly of the TIM22 import complexes. Traffic 4:144-152
31. Nishimura K, Yasumura K, Igarashi K, Harashima S, Kakinuma Y (1999a) Transcription of some PHO genes in Saccharomyces cerevisiae is regulated by Spt7p. Yeast 15:1711-1717
32. Nishimura K, Yasumura K, Igarashi K, Kakinuma Y (1999b) Involvement of Spt7p in vacuolar polyphosphate level of Saccharomyces cerevisiae. Biochem Biophys Res Commun 257:835-838
33. Pfanner N, Geissler A (2001) Versatility of the mitochondrial protein import machinery. Nat Rev Mol Cell Biol 2:339-349
34. Sambrook J, Russell DW (2001) Molecular Cloning: A Laboratory Manual, 3rd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
35. Senapin S, Clark-Walker GD, Chen XJ, Seraphin B, Daugeron MC (2003) RRP20, a component of the 90S preribosome, is required for pre-18S rRNA processing in Saccharomyces cerevisiae. Nucleic Acids Res 31:2524-2533
36. Sirrenberg C, Bauer MF, Guiard B, Neupert W, Brunner M (1996) Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22. Nature 384:582-585
37. Sirrenberg C, Endres M, Folsch H, Stuart RA, Neupert W, Brunner M (1998) Carrier protein import into mitochondria mediated by the intermembrane proteins Tim10/Mrs11 and Tim12/Mrs5. Nature 391:912-915
38. Stribinskis V, Gao GJ, Ellis SR, Martin NC (2001) Rpm2, the protein subunit of mitochondrial RNase P in Saccharomyces cerevisiae, also has a role in the translation of mitochondrially encoded subunits of cytochrome c oxidase. Genetics 158:573-585
39. Thompson JD, Higgins DG, Gibson TJ (1994) CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22:4673-4680
40. Thorsness PE, White KH, Fox TD (1993) Inactivation of YME1, a member of the ftsH-SEC18-PAS1-CDC48 family of putative ATPase-encoding genes, causes increased escape of DNA from mitochondria in Saccharomyces cerevisiae. Mol Cell Biol 13:5418-5426
41. Tranebjaerg L, Hamel BC, Gabreels FJ, Renier WO, Van Ghelue M (2000) A de novo missense mutation in a critical domain of the X-linked DDP gene causes the typical deafness-dystonia-optic atrophy syndrome. Eur J Hum Genet 8:464-467
42. Zuo XM (2001) Characterisation of the Saccharomyces cerevisiae MGM101 gene involved in the replication of mitochondrial DNA. PhD Thesis. The Australian National University, Canberra