Reversed polarized delivery of an aquaporin-2 mutant causes dominant nephrogenic diabetes insipidus

Journal of Cell Biology

Volumn 163, Issue 5, 2003, Pages 1099-1109

  Kamsteeg, Erik Jan ^a   Bichet, Daniel G ^b   Konings, Irene B M ^a   Nivet, Hubert ^c   Lonergan, Michelle ^b   Arthus, Marie Françoise ^b   Van Os, Carel H ^a   Deen, Peter M T ^a,d  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^c UNIVERSITY HOSPITAL OF TOURS   (France)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Aquaporin; Dominant disease; Hetero oligomerization; Missorting; Water channel

Indexed keywords

AQUAPORIN 2; LEUCINE; MUTANT PROTEIN; TYROSINE; VASOPRESSIN;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; AUTOSOMAL DISORDER; AUTOSOMAL DOMINANT INHERITANCE; BASOLATERAL MEMBRANE; BODY WATER; CARBOXY TERMINAL SEQUENCE; CELL POLARITY; CELL VACUOLE; CONTROLLED STUDY; FRAMESHIFT MUTATION; HUMAN; KIDNEY COLLECTING TUBULE; KIDNEY CONCENTRATING CAPACITY; NEPHROGENIC DIABETES INSIPIDUS; NONHUMAN; OLIGOMERIZATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN TARGETING; WATER ABSORPTION; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; AQUAPORIN 2; AQUAPORIN 6; AQUAPORINS; BASE SEQUENCE; CELL LINE; CELL MEMBRANE; CELL POLARITY; CYTOPLASMIC VESICLES; DIABETES INSIPIDUS, NEPHROGENIC; FRAMESHIFT MUTATION; HUMANS; LEUCINE; MOLECULAR SEQUENCE DATA; OOCYTES; PEDIGREE; PHENOTYPE; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; TYROSINE; VASOPRESSINS; XENOPUS LAEVIS;

ANIMALIA;

EID: 0346849713     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200309017     Document Type: Article

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