Affinity and intrinsic efficacy (IE) of 5′-carbamoyl adenosine analogues for the A1 adenosine receptor - Efforts towards the discovery of a chronic ventricular rate control agent for the treatment of atrial fibrillation (AF)

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 2, 2004, Pages 535-539

  Palle, Venkata P ^a   Varkhedkar, Vaibhav ^a   Ibrahim, Prabha ^a   Ahmed, Hiba ^a   Li, Zhihe ^a   Gao, Zhenhai ^a   Ozeck, Mark ^a   Wu, Yuzhi ^a   Zeng, Dewan ^a   Wu, Lin ^a   Leung, Kwan ^a   Chu, Nancy ^a   Zablocki, Jeff A ^a  

^a CV THERAPEUTICS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' DEOXY N 6 CYCLOPENTYLADENOSINE; ADENOSINE A1 RECEPTOR; ANTIARRHYTHMIC AGENT; CARBAMIC ACID DERIVATIVE; CVT 2759; CVT 2771; TECADENOSON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SCREENING; FIBROBLAST; GUINEA PIG; HEART ATRIUM FIBRILLATION; HEART VENTRICLE; HUMAN; HUMAN CELL; ISOLATED HEART; KIDNEY CELL; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

CAVIA PORCELLUS; SUS SCROFA;

EID: 0346729854     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.09.094     Document Type: Article

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