The tetraspanin protein, CD9, is expressed by progenitor cells committed to oligodendrogenesis and is linked to β1 integrin, CD81, and Tspan-2

GLIA

Volumn 40, Issue 3, 2002, Pages 350-359

  Terada, Nobuo ^a   Baracskay, Karen ^b   Kinter, Mike ^a   Melrose, Shona ^c   Brophy, Peter J ^c   Boucheix, Claude ^d   Bjartmar, Carl ^a   Kidd, Grahame ^a   Trapp, Bruce D ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d HÔPITAL PAUL BROUSSE   (France)

Author keywords

Development; Differentiation; Myelination; Oligodendrocyte; Progenitor cell; Tetraspanin

Indexed keywords

ANTIGEN; BETA1 INTEGRIN; CD81 ANTIGEN; CD9 ANTIGEN; CHONDROITIN SULFATE PROTEOGLYCAN 4; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; NERVE PROTEIN; OLIGODENDROCYTE O ANTIGEN, MOUSE; OLIGODENDROCYTE O ANTIGEN, RAT; PROTEOGLYCAN; TETRASPANIN 2; TSPAN2 PROTEIN, MOUSE; TSPAN2 PROTEIN, RAT;

ANIMAL; ARTICLE; BIOTINYLATION; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOUSE; MOUSE MUTANT; MYELIN SHEATH; NEWBORN; OLIGODENDROGLIA; RAT; SPRAGUE DAWLEY RAT; STEM CELL;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS; ANTIGENS, CD; ANTIGENS, CD29; ANTIGENS, DIFFERENTIATION; BIOTINYLATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL MEMBRANE; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MYELIN SHEATH; NERVE TISSUE PROTEINS; OLIGODENDROGLIA; PROTEOGLYCANS; RATS; RATS, SPRAGUE-DAWLEY; STEM CELLS;

EID: 0346668357     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.10134     Document Type: Article

References (20)

1. Azorsa DO, Moog S, Cazenave JP, Lanza F. 1999. A general approach to the generation of monoclonal antibodies against membranes of the tetraspan superfamily using recombinant GST fusion proteins. J Immunol Methods 229:35-48.
2. Birling M-C, Tait S, Hardy RJ, Brophy PJ. 1999. A novel tetraspan protein in cells of the oligodendrocyte lineage. J Neurochem 73:2600-2608.
3. Blaschuk KL, Frost EE, ffrench-Constant C. 2000. The regulation of proliferation and differentiation in oligodendrocyte progenitor cells by alphaV integrins. Development 127:1961-1969.
4. Boucheix C, Rubinstein E. 2001. Tetraspanins. Cell Mol Life Sci 58:1189-1205.
5. Buttery PC, ffrench-Constant C. 1999. Laminin-2/integrin interactions enhance myelin membrane formation by oligodendrocytes. Mol Cell Neurosci 14:199-212.
6. Hemler ME. 2001. Specific tetraspanin functions. J Cell Biol 155:1103-1107.
7. Kagawa T, Mekada E, Shishido Y, Ikenaka K. 1997. Immune system-related CD9 is expressed in mouse central nervous system myelin ata very late stage of myelination. J Neurosci Res 50:312-320.
8. Le Naour F, Rubinstein E, Jasmin C, Prenant M, Boucheix C. 2000. Severely reduced female fertility in CD9-deficient mice. Science 287:319-324.
9. Levy S, Todd SC, Maecker HT. 1998. CD81 (TAPA-1): A molecule involved in signal transduction and cell adhesion in the immune system. Ann Rev Immunol 16:89-109.
10. Milner R, ffrench-Constant C. 1994. A developmental analysis of oligodendroglial integrins in primary cells: Changes in alpha v-associated beta subunits during differentiation. Development 120:3497-3506.
11. Miyake M, Nakano K, Ieki Y, Adachi M, Huang CL, Itoi S, Koh T, Taki T. 1995. Motility related protein 1 (MRP-1/CD9) expression: Inverse correlation with metastases in breast cancer. Cancer Res 55:4127-4131.
12. Nakamura Y, Iwamoto R, Mekada E. 1996. Expression and distribution of CD9 in myelin of the central and peripheral nervous systems. Am J Pathol 149:575-583.
13. Nakamura Y, Handa K, Iwamoto R, Tsukamoto T, Takahashi M, Mekada E. 2001. Immunohistochemical distribution of CD9, heparin binding epidermal growth factor-like growth factor, and integrin alpha3beta1 in normal human tissues. J Histochem Cytochem 49:439-444.
14. Nery S, Wichterle H, Fishell G. 2001. Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain. Development 128:527-540.
15. Relvas JB, Setzu A, Baron W, Buttery PC, La Flamme SE, Franklin JM, ffrench-Constant C. 2001. Expression of dominant-negative and chimeric subunits reveals an essential role for beta1 integrin during myelination. Curr Biol 11:1039-1043.
16. Rubinstein E, Le Naour F, Lagaudriere-Gesbert C, Billard M, Conjeaud H, Boucheix C. 1996. CD9, CD63, CD81, and CD82 are components of a surfaee tetraspan network connected to HLA-DR and VLA integrins. Eur J Immunol 26:2657-2665.
17. Sullivan CD, Geisert EE. 1998. Expression of rat target of the anti-proliferative antibody (TAPA) in the developing brain. J Comp Neurol 396:366-380.
18. Tanaka S, Suzuki K, Watanabe M, Matsuda A, Tone S, Koike T. 1998. Upregulation of a new microglial gene, mrf-1, in response to programmed neuronal cell death and degeneration. J Neurosci 18:6358-6369.
19. Tole S, Patterson PH. 1993. Distribution of CD9 in the developing and mature rat nervous system. Dev Dyn 197:94-106.
20. Trapp BD, Nishiyama A, Cheng D, Macklin W. 1997. Differentiation and death of premyelinating oligodendrocytes in developing rodent brain. J Cell Biol 137:459-468.