Modulation of Ca2+ Channel Currents by a Novel Antidementia Drug N-(4-Acetyl-1-piperazinyl)-p-fluorobenzamide Monohydrate (FK960) in Rat Hippocampal Neurons

Journal of Pharmacology and Experimental Therapeutics

Volumn 308, Issue 1, 2004, Pages 120-126

  Wang, Feng ^a   Matsuoka, Nobuya ^a   Mutoh, Seitaro ^a   Kaneko, Shuji ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; BACLOFEN; CALCIUM; CALCIUM CHANNEL; GUANINE NUCLEOTIDE BINDING PROTEIN; N (4 ACETYL 1 PIPERAZINYL) 4 FLUOROBENZAMIDE; NOOTROPIC AGENT; PROTEIN KINASE; PROTEIN KINASE C INHIBITOR; SOMATOSTATIN; VOLTAGE GATED CALCIUM CHANNEL; BENZAMIDE DERIVATIVE; N-(4-ACETYL-1-PIPERAZINYL) -4-FLUOROBENZAMIDE MONOHYDRATE; PIPERAZINE DERIVATIVE;

ADOLESCENT; ANIMAL CELL; ARTICLE; BRAIN CELL; CALCIUM CURRENT; CONTROLLED STUDY; DEMENTIA; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; MODULATION; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NEWBORN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SOMATOSTATIN RELEASE; ANIMAL; CYTOLOGY; DRUG INTERACTION; METABOLISM; NERVE CELL; PHYSIOLOGY; WISTAR RAT;

ANIMALS; BENZAMIDES; CALCIUM CHANNELS; DRUG INTERACTIONS; ENZYME ACTIVATION; GTP-BINDING PROTEINS; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; NEURONS; PIPERAZINES; PROTEIN KINASES; RATS; RATS, WISTAR; SOMATOSTATIN;

EID: 0346497727     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.057687     Document Type: Article

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