Identification and Characterization of a Series of Nucleoside Adducts Formed by the Reaction of 2′-Deoxyguanosine and 1,2,3,4-Diepoxybutane under Physiological Conditions

Chemical Research in Toxicology

Volumn 16, Issue 12, 2003, Pages 1606-1615

  Zhang, Xin Yu ^a   Elfarra, Adnan A ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 HYDROXY 2 OXIRANYLETHYL) 2' DEOXYGUANOSINE; 1 [3 CHLORO 2 HYDROXY 1 (HYDROXYMETHYL)PROPYL] 2' DEOXYGUANOSINE 6,7,8,9 TERAHYDRO 1H PYRIMIDO[2,1 B]PURINIUM; 2 AMINO 7 (3 CHLORO 2,4 DIHYDROXYBUTYL) 1,7 DIHYDRO 6H PURIN 6 ONE; 6 OXO 2 AMINO 9 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 7 (2 HYDROXY 2 OXIRANYLETHYL) 6,9 DIHYDRO 1H PURINIUM; 7,8 DIHYDROXY 3 (2 DEOXY BETA DEXTRO ERYTHRO PENTOFURANOSYL) 3,5,6,7,8,9 HEXAHYDRO 1,3 DIAZEPINO[1,2 A]PURIN 11(11H) ONE; BUTADIENE DIEPOXIDE; DEOXYGUANOSINE DERIVATIVE; KETONE DERIVATIVE; N (2 HYDROXY 1 OXIRANYLETHYL) 2' DEOXYGUANOSINE; PURINE NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ALKALINITY; ALKYLATION; ARTICLE; CHEMICAL STRUCTURE; DIASTEREOISOMER; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ALKYLATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; EPOXY COMPOUNDS; HYDROGEN-ION CONCENTRATION; KINETICS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEOSIDES;

EID: 0346368322     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0341355     Document Type: Article

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