-
1
-
-
0019195506
-
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
-
Furchgott, R. F., and Zawadzki, J. V. (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288, 373-376.
-
(1980)
Nature
, vol.288
, pp. 373-376
-
-
Furchgott, R.F.1
Zawadzki, J.V.2
-
2
-
-
0021223879
-
The nature of endothelium-derived vascular relaxant factor
-
Griffith, T. M., Edwards, D. H., Lewis, M. J., Newby, A. C., and Hendreson, A. H. (1984) The nature of endothelium-derived vascular relaxant factor. Nature 308, 645-647.
-
(1984)
Nature
, vol.308
, pp. 645-647
-
-
Griffith, T.M.1
Edwards, D.H.2
Lewis, M.J.3
Newby, A.C.4
Hendreson, A.H.5
-
3
-
-
0022481682
-
Cyclic guanosine monophosphate as a mediator of vasodilation
-
Murad, F. (1986) Cyclic guanosine monophosphate as a mediator of vasodilation. J. Clin. Invest. 78, 1-5.
-
(1986)
J. Clin. Invest.
, vol.78
, pp. 1-5
-
-
Murad, F.1
-
4
-
-
0023198721
-
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
-
Palmer, R. M. J., Ferrige, A. G., and Moncada, S. (1987) Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327, 524-526.
-
(1987)
Nature
, vol.327
, pp. 524-526
-
-
Palmer, R.M.J.1
Ferrige, A.G.2
Moncada, S.3
-
5
-
-
0023912670
-
Vascular endothelial cells synthesize nitric oxide from L-arginine
-
Palmer, R. M., Ashton, D. S., and Moncada, S. (1988) Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 333, 664-666.
-
(1988)
Nature
, vol.333
, pp. 664-666
-
-
Palmer, R.M.1
Ashton, D.S.2
Moncada, S.3
-
6
-
-
0026623110
-
Endothelial nitric oxide synthase: Molecular cloning and characterization of a distinct constitutive enzyme isoform
-
Lamas, S., Marsden, P. A., Li, G. K., Tempst, P., and Michel, T. (1992) Endothelial nitric oxide synthase: Molecular cloning and characterization of a distinct constitutive enzyme isoform. Proc. Natl. Acad. Sci. USA 89, 6348-6352.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6348-6352
-
-
Lamas, S.1
Marsden, P.A.2
Li, G.K.3
Tempst, P.4
Michel, T.5
-
7
-
-
0026764107
-
Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase
-
Sessa, W. C., Harrison, J. K., Barber, C. M., Zeng, D., Durieux, M. E., D'Angelo, D. D., Lynch, K. R., and Peach, M. J. (1992) Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase. J. Biol. Chem. 267, 15274-15276.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 15274-15276
-
-
Sessa, W.C.1
Harrison, J.K.2
Barber, C.M.3
Zeng, D.4
Durieux, M.E.5
D'Angelo, D.D.6
Lynch, K.R.7
Peach, M.J.8
-
8
-
-
0024296032
-
Endothelium-derived relaxing factor release on activation of NMDA receptors suggests a role as intercellular messenger in the brain
-
Garthwaite, J., Charles, S. L., and Chess-Williams, R. (1988) Endothelium-derived relaxing factor release on activation of NMDA receptors suggests a role as intercellular messenger in the brain. Nature 336, 385-387.
-
(1988)
Nature
, vol.336
, pp. 385-387
-
-
Garthwaite, J.1
Charles, S.L.2
Chess-Williams, R.3
-
9
-
-
0343046540
-
Formation of nitric oxide from L-arginine in the central nervous system: A transduction mechanism for stimulation of the soluble guanylate cyclase
-
Knowles, R. G., Palacios, M., Palmer, R. M., and Moncada, S. (1989) Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase. Proc. Natl. Acad. Sci. USA 86, 5159-5162.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5159-5162
-
-
Knowles, R.G.1
Palacios, M.2
Palmer, R.M.3
Moncada, S.4
-
10
-
-
0025191219
-
Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme
-
Bredt, D. S., and Snyder, S. H. (1990) Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc. Natl. Acad. Sci. USA 87, 682-685.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 682-685
-
-
Bredt, D.S.1
Snyder, S.H.2
-
11
-
-
0026744830
-
Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line
-
Lyons, C. R., Orloff, G. J., and Cunningham, J. M. (1992) Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J. Biol. Chem. 267, 6370-6374.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 6370-6374
-
-
Lyons, C.R.1
Orloff, G.J.2
Cunningham, J.M.3
-
12
-
-
0026569273
-
Cloning and characterization of inducible nitric oxide synthase from mouse macrophages
-
Xie, Q. W., Cho, H. J., Calaycay, J., Mumford, R. A., Swiderek, K. M., Lee, T. D., Ding, A., Troso, T., and Nathan, C. (1992) Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science 256, 225-228.
-
(1992)
Science
, vol.256
, pp. 225-228
-
-
Xie, Q.W.1
Cho, H.J.2
Calaycay, J.3
Mumford, R.A.4
Swiderek, K.M.5
Lee, T.D.6
Ding, A.7
Troso, T.8
Nathan, C.9
-
13
-
-
0022640297
-
Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
-
Gryglewski, R. J., Palmer, R. M., and Moncada, S. (1986) Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320, 454-456.
-
(1986)
Nature
, vol.320
, pp. 454-456
-
-
Gryglewski, R.J.1
Palmer, R.M.2
Moncada, S.3
-
14
-
-
0024311321
-
Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion
-
McCall, T. B., Boughton-Smith, N. K., Palmer, R. M., Whittle, B. J. R., and Moncada, S. (1989) Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion. Biochem. J. 261, 293-296.
-
(1989)
Biochem. J.
, vol.261
, pp. 293-296
-
-
McCall, T.B.1
Boughton-Smith, N.K.2
Palmer, R.M.3
Whittle, B.J.R.4
Moncada, S.5
-
15
-
-
0025189864
-
Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
-
Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., and Freeman, B. (1990) Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA 87, 1620-1624.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 1620-1624
-
-
Beckman, J.S.1
Beckman, T.W.2
Chen, J.3
Marshall, P.A.4
Freeman, B.5
-
16
-
-
0037432615
-
Multiple pathways of peroxynitrite cytotoxicity
-
Szabo, C. (2003) Multiple pathways of peroxynitrite cytotoxicity. Toxicol. Lett. 140-141, 105-112.
-
(2003)
Toxicol. Lett.
, vol.140-141
, pp. 105-112
-
-
Szabo, C.1
-
17
-
-
28044464985
-
Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases
-
Cleeter, M. W. J., Cooper, J. M., Darely-Usmar, V., Moncada, S., and Schapira, A. H. (1994) Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases. FEBS Lett. 345, 50-54.
-
(1994)
FEBS Lett.
, vol.345
, pp. 50-54
-
-
Cleeter, M.W.J.1
Cooper, J.M.2
Darely-Usmar, V.3
Moncada, S.4
Schapira, A.H.5
-
18
-
-
0027945838
-
Nitric oxide potently and reversibly deenergizes mitochondria
-
Schweizer, M., and Richter, C. (1994) Nitric oxide potently and reversibly deenergizes mitochondria. Biochem. Biophys. Res. Commun. 204, 169-175.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.204
, pp. 169-175
-
-
Schweizer, M.1
Richter, C.2
-
19
-
-
0028145462
-
Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes
-
Bolaños, J. P., Peuchen, S., Heales, S. J., Land, J. M., and Clark, J. B. (1994) Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes. J. Neurochem. 63, 910-916.
-
(1994)
J. Neurochem.
, vol.63
, pp. 910-916
-
-
Bolaños, J.P.1
Peuchen, S.2
Heales, S.J.3
Land, J.M.4
Clark, J.B.5
-
20
-
-
0028134892
-
Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase
-
Brown, G. C., and Cooper, C. E. (1994) Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Lett. 356, 295-298.
-
(1994)
FEBS Lett.
, vol.356
, pp. 295-298
-
-
Brown, G.C.1
Cooper, C.E.2
-
21
-
-
0033573981
-
On the mechanism by which vascular endothelial cells regulate their oxygen consumption
-
Clementi, E., Brown, G. C., Foxwell, N., and Moncada, S. (1999) On the mechanism by which vascular endothelial cells regulate their oxygen consumption. Proc. Nat. Acad. Sci. USA 96, 1559-1562.
-
(1999)
Proc. Nat. Acad. Sci. USA
, vol.96
, pp. 1559-1562
-
-
Clementi, E.1
Brown, G.C.2
Foxwell, N.3
Moncada, S.4
-
22
-
-
0033529656
-
Perspectives on oxygen sensing
-
Semenza, G. L. (1999) Perspectives on oxygen sensing. Cell 96, 281-284.
-
(1999)
Cell
, vol.96
, pp. 281-284
-
-
Semenza, G.L.1
-
23
-
-
0034687662
-
The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival or death
-
Beltrán, B., Mathur, A., Duchen, M., Erusalimsky, J. D., and Moncada, S. (2000) The effect of nitric oxide on cell respiration: a key to understanding its role in cell survival or death. Proc. Natl. Acad. Sci. USA 97, 14602-14607.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14602-14607
-
-
Beltrán, B.1
Mathur, A.2
Duchen, M.3
Erusalimsky, J.D.4
Moncada, S.5
-
24
-
-
0019127933
-
Effects of ionophores and metabolic inhibitors on the mitochondrial membrane potential within isolated hepatocytes as measured with the safranine method
-
Akerman, K. E. O., and Jarvisalo, J. O. (1980) Effects of ionophores and metabolic inhibitors on the mitochondrial membrane potential within isolated hepatocytes as measured with the safranine method. Biochem. J. 192, 183-190.
-
(1980)
Biochem. J.
, vol.192
, pp. 183-190
-
-
Akerman, K.E.O.1
Jarvisalo, J.O.2
-
25
-
-
0035909948
-
Different responses of astrocytes and neurons to nitric oxide: The role of glycolytically-generated ATP in astrocyte protection
-
Almeida, A., Almeida, J., Bolaños, J. P., and Moncada, S. (2001) Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically-generated ATP in astrocyte protection. Proc. Natl. Acad. Sci. USA 98, 15294-15299.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 15294-15299
-
-
Almeida, A.1
Almeida, J.2
Bolaños, J.P.3
Moncada, S.4
-
26
-
-
0034624984
-
Nitric oxide inhibits tumor necrosis factor-α induced apoptosis by reducing the generation of ceramide
-
De Nadai, C., Sestili, P., Cantoni, O., Lievremont, J. P., Sciorati, C., Barsacchi, R., Moncada, S., Meldolesi, J., and Clementi, E. (2000) Nitric oxide inhibits tumor necrosis factor-α induced apoptosis by reducing the generation of ceramide. Proc. Natl. Acad. Sci. USA 97, 5480-5485.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5480-5485
-
-
De Nadai, C.1
Sestili, P.2
Cantoni, O.3
Lievremont, J.P.4
Sciorati, C.5
Barsacchi, R.6
Moncada, S.7
Meldolesi, J.8
Clementi, E.9
-
27
-
-
0036850413
-
Cyclic GMP-dependent inhibition of acid sphingomyelinase by nitric oxide: An early step in protection against apoptosis
-
Barsacchi, R., Perrotta, C., Sestili, P., Cantoni, O., Moncada, S., and Clementi, E. (2002) Cyclic GMP-dependent inhibition of acid sphingomyelinase by nitric oxide: an early step in protection against apoptosis. Cell Death Differ. 9, 1248-1255.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 1248-1255
-
-
Barsacchi, R.1
Perrotta, C.2
Sestili, P.3
Cantoni, O.4
Moncada, S.5
Clementi, E.6
-
28
-
-
0037382346
-
Activation of endothelial nitric-oxide synthase by tumor necrosis factor-α: A novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3′ kinase, and Akt
-
Barsacchi, R., Perrotta, C., Bulotta, S., Moncada, S., Borgese, N., and Clementi, E. (2003) Activation of endothelial nitric-oxide synthase by tumor necrosis factor-α: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3′ kinase, and Akt. Mol. Pharmacol. 63, 886-895.
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 886-895
-
-
Barsacchi, R.1
Perrotta, C.2
Bulotta, S.3
Moncada, S.4
Borgese, N.5
Clementi, E.6
-
29
-
-
0347579845
-
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
-
Nisoli, E., Clementi, E., Paolucci, C., Cozzi, V., Tonello, C., Sciorati, C., Bracale, R., Valerio, A., Francolini, M., Moncada, S., and Carruba, M. O. (2003) Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science 299, 896-899.
-
(2003)
Science
, vol.299
, pp. 896-899
-
-
Nisoli, E.1
Clementi, E.2
Paolucci, C.3
Cozzi, V.4
Tonello, C.5
Sciorati, C.6
Bracale, R.7
Valerio, A.8
Francolini, M.9
Moncada, S.10
Carruba, M.O.11
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