Two Trichomonas vaginalis Loci Encoding for Distinct Cysteine Proteinases Show a Genomic Linkage with Putative Inositol Hexakisphosphate Kinase (IP6K2) or an ABC Transporter Gene

Journal of Eukaryotic Microbiology

Volumn 50, Issue SUPPL., 2003, Pages 702-705

  Del Rosario León Sicairos, Claudia ^a   Pérez Martînez, Iza ^a   Álvarez Sánchez, María Elizbeth ^a   López Villaseñor, Imelda ^b   Arroyo, Rossana ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; CYSTEINE PROTEINASE; INOSITOL HEXAKISPHOSPHATE KINASE; PHOSPHOTRANSFERASE; PROTOZOAL PROTEIN;

ENZYME;

ANIMAL; CHROMOSOME MAP; CONFERENCE PAPER; ENZYMOLOGY; GENETICS; HUMAN; MAMMAL; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; TRICHOMONAS VAGINALIS;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CHROMOSOME MAPPING; CYSTEINE ENDOPEPTIDASES; HUMANS; MAMMALS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PHOSPHOTRANSFERASES (PHOSPHATE GROUP ACCEPTOR); PROTOZOAN PROTEINS; TRICHOMONAS VAGINALIS;

ANIMALIA; MAMMALIA; PROTOZOA; TRICHOMONAS VAGINALIS;

EID: 0346336059     PISSN: 10665234     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1550-7408.2003.tb00695.x     Document Type: Conference Paper

References (26)

1. Alvarez-Sánchez, M.E., Avila-González, L., Becerril-García, C., Fattel-Facenda, L.V. & Arroyo, R. 2000. A novel cysteine proteinase (CP65) of Trichomonas vaginalis involved in cytotoxicity. Microb. Pathog., 28:1-10.
2. Arroyo, R. & Alderete, J.F. 1989. Trichomonas vaginalis surface proteinase activity is necessary for parasite adherence to epithelial cells. Infect. Immun., 57:2991-2997.
3. Arroyo, R. & Alderete, J.F. 1995. Two Trichomonas vaginalis surface proteinases bind to host epithelial cells and are related to levels of cytoadherence and cytotoxicity. Arch. Med. Res., 26:279-285.
4. Chi, T. & Crabtree, G. 2000. Inositol phosphates in the nucleus. Science, 287:1937-1939.
5. Espinosa, N., Hernández, R., López-Griego, L., Arroyo, R. & López-Villaseñor, I. 2001. Differences between coding and non-coding regions in the Trichomonas vaginalis genome: an actin gene as a locus model. Act. Trop., 78:147-154.
6. Espinosa, N., Hernández, R., López-Griego, L. & López-Villaseñor, I. 2002. Separable putative polyadenylation and cleavage motifs in Trichomonas vaginalis mRNAs. Gene, 289:81-86.
7. Johnson, P.J., Schuck, B.L. & Delgadillo, M.G. 1994. Analysis of a single-domain P-glycoprotein-like gene in the early-diverging protist Trichomonas vaginalis. Mol. Biochem. Parasitol., 66:127-137.
8. Klein, I., Sarkadi, B. & Varadi, A. 1999. An inventory of the human ABC proteins. Biochem, Bioph. Acta, 6:237-262.
9. Légaré, D., Richard, D., Mukhopadhyay, R., Stierhof, Y.D., Rosen, B.P., Haimeur, A., Papadopoulou, B. & Ouellette, M. 2001. The Leishmania ATP-binding cassette protein PGPA is an intracellular metal-thiol transporter ATPase. J. Biochem. Parasitol., 13:26301-25307.
10. Liston, D.R. & Johnson, P.J. 1998. Gene transcription in Trichomonas vaginalis. Parasitol. Today, 14:261-264.
11. Liston, D.R. & Johnson, P.J. 1999. Analysis of a ubiquitous promoter element in a primitive eukaryote: early evolution of the initiator element. Mol. Cell. Biol., 19:2380-2388.
12. Mallinson, D.J., Lockwood, B.C., Coombs, G.H. & North, M. 1994. Identification and molecular cloning of four cysteine proteinase genes from the pathogenic protozoan Trichomonas vaginalis. Microbiol., 140:2725-2735.
13. Mendoza-López, R., Becerril-García, C., Fattel-Facenda, L.V., Avila-González, L., Ruiz-Tachiquín, M., Ortega-López, J. & Arroyo, R. 2000. CP30, a cysteine proteinase involved in Trichomonas vaginalis cytoadherence. Infect. Immun., 68:1-6.
14. Morrison, B.H., Bauer, J.A., Kalvakolanu D.V. & Lindner, D.J. 2001. Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-β in ovarian carcinoma cells. J. Biol. Chem., 276:24965-24970.
15. Neale, K. & Alderete, J.F. 1990. Analysis of the proteinases of representative Trichomonas vaginalis isolates. Infect. Immun., 581:157-162.
16. North, M.J., Mottram, J.C. & Coombs, G.H. 1990. Cysteine proteinase of parasitic protozoa. Parasitol. Today, 6:270-275.
17. Rosenberg, M.F., Velarde, G., Ford, R.C., Martín, C., Berridge, G., Kerr, I.D., Callaghan, R., Schmidlin, A., Wcoding, C., Linton, K.J. & Higgins, C.F. 2001. Repacking of the tremsmembrane domains of P-glycoprotein during the transport ATPase cycle. EMBO J., 20:5615-5625.
18. Saiardi, A., Caffrey, J.J., Snyder, S.H. & Shears, S.B. 2000. The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuoles biogenesis. J. Biol. Chem., 275:24686-24692.
19. Saiardi, A., Erdjument-Bromage, H., Snowman, A.M, Tempst, P. & Snyder, S.H. 1999. Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinase. Curr Biol., 9:1323-1326.
20. Saiardi, A., Nagata, E., Luo, H.R., Snowman, A.M. & Snyder, S.H. 2001. Identification and characterization of a novel inositol hexakisphosphate kinase. J. Biol. Chem. 276:39179-39185.
21. Sajid, M. & McKerrow, J.H. 2002. Cysteine protease of parasitic organisms. Mol. Biochem. Parasitol., 120:1-21.
22. Sanger, F., Nicklen, S. & Coulson, A.R. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA, 74:5463-5467.
23. Shah, P.M., Stiles, J.K., Finley, R.W., Lushbaugh, W.B. & Meade, J.C. 2001. Trichomonas vaginalis: characterization of a family of P-type ATPase genes. Parasitol. Int., 51:41-51.
24. Van Haastert, P.J.M. & Van Dijken, P. 1997. Biochemistry and genetics of inositol phosphate metabolism in Dictyostelium. FEBS Lett., 410:39-43.
25. Voglmaier, S., Bembenek, M., Kaplin, A., Dormán, G., Olszewsky, J., Prestwich, G. & Snyder, S. 1996. Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor. Proc. Natl. Acad. Sci. USA. 93:4305-4310.
26. Wang, A.L. & Wang, C.C. 1985. Isolation and characterization of DNA from Tritrichomonas foetus and Trichomonas vaginalis. Mol. Biochem. Parasitol., 14:323-335.