Regulation of retinal phosphoinositide 3-kinase activity in P85α-subunit knockout mice

Advances in Experimental Medicine and Biology

Volumn 533, Issue , 2003, Pages 369-376

  Rajala, Raju V S ^a,b   McClellan, Mark E ^a,b   Ash, John D ^a,b   Anderson, Robert E ^a,b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECEPTOR SUBUNIT;

ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME REGULATION; ENZYME SUBUNIT; HISTOLOGY; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PHOTORECEPTOR; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RETINA DEGENERATION; RETINA DISEASE; WESTERN BLOTTING;

ANIMALIA;

EID: 0346271744     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0067-4_47     Document Type: Conference Paper

References (25)

1. Antonetti DA, Algenstaedt P, Kahn CR., 1996, Insulin receptor substrate I binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain. Mol Cell Biol., 16:2195-2203.
2. D'Mello RD, Borodez K, Solto SP., 1997, Insulin like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling. J Neurosci., 17:1548-1560.
3. Dhand R, Hiles I, Panayotou G, Roche S, Fry MJ, Gout I, Totty NF, Truong O, Vicendo P, Yonezawa K, Kasuga M, Courtneidge SA, Waterfield MD., 1994, PI3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity. EMBO J., 13:522-533.
4. Fruman DA, Meyers RE, Cantley LC., 1998, Phosphoinositide kinases. Ann Rev Biochem., 67:481-507.
5. Fruman DA, Snapper SB, Yballe CM, Davidson L, Yu JY, Alt FW, Cantley LC., 1999, Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85α. Science., 283:393-397.
6. Guo XX, Ghalayini AJ, Chen HM, Anderson RE., 1997, Phosphatidylinositol 3-kinase in bovine photoreceptor rod outer segments. Invest Ophthalmol Vis Sci., 38:1873-1882.
7. Guo XX, Huang Z, Bell MW, Chen H, Anderson RE., 2000, Tyrosine phosphorylation is involved in phosphatidylinositol 3-kinase activation in bovine rod outer segments. Mol Vis., 6:216-221.
8. Hu P, Mondino A, Skolnik EY, Schlessinger J., 1993, Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85. Mol Cell Biol., 13:7677-7688.
9. Inukai K, Anai M, Van Breda E, Hosaka T, Katagiri H, Funaki M, Fukushima Y, Ogihara T, Yazaki Y, Kikuchi, Oka Y, Asano T., 1996, A novel 55-kDa regulatory subunit for phosphatidylinositol 3-kinase structurally similar to p55PIK is generated by alternative splicing of the p85α gene. J. Biol Chem., 271:5317-5320.
10. Inukai K, Funaki M, Ogihara T, Katagiri H, Kanda A, Anai M, Fukushima Y, Hosaka T, Suzuki M, Shin BC, Takata K, Yazaki Y, Kikuchi M, Oka Y, Asano T., 1997, p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50α, p55α, and p85α with different PI 3-kinase activity elevating responses to insulin. J Biol. Chem., 272:7873-7882.
11. Kaplan DR, Whitman M, Schaffhausen B, Pallas DC, White M. Cantley LC, Roberts TM., 1987, Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity. Cell., 50:1021-1029.
12. Klippel A, Escobedo JA, Fantl WJ, Williams LT., 1992, The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor-β receptor. Mol Cell Biol., 12:1451-1459.
13. McGlade CJ, Ellis C, Reedijk M, Anderson D, Reith AD, Panayotou G, End P, Bernstein A, Kazlauskas A, Waterfiled MD, Paswon T., 1992, SH2 domains of the p85α subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors. Mol Cell Biol., 12:991-997.
14. Noell WK., 1980, Possible mechanisms of photoreceptor damage by light in mammalian eyes. Vis Res., 20:1163-1171.
15. Otsu M, Hiles I, Gout I, Fry MJ, Ruiz-Larrea F, Panayotou G, Thompson A, Dhand R, Hsuan J, Totty N., 1991, Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI 3-kinase. Cell., 65:91-104.
16. Rajala RVS, Anderson RE., 2001, Interaction of the insulin receptor β-subunit with phosphatidylinositol 3-kinase in bovine ROS. Invest Ophthalmol Vis Sci., 42:3110-3117.
17. Rajala RVS, McClellan ME, Ash JD, Anderson RE., 2002, In vivo regulation of phosphoinositide 3-kinase in retina through light-induced tyrosine phosphorylation of the insulin receptor β-subunit. J Biol. Chem., 277:43319-43326.
18. Saltiel AR, Pessin JE., 2002, Insulin signaling pathways in time and space. Trends Cell Biol., 12:65-71.
19. Skolnik, EY, Margolis B, Mohammadi M, Lowenstein E, Fischer R, Drepps A, Ullrich, A, Schlessinger J., 1991, Cloning of PI3K-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases. Cell., 65:83-90.
20. Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Robserts T, Ratnofsky S, Lechleider RJ, Neel BG, Birge RB, Fajardo JE, Chou MM, Hanafusa H, Schaffhausen B, Cantley LC., 1993, SH2 domains recognize specific phosphopeptide sequences. Cell., 72:767-778.
21. Spear N, Estevez AG, Barbeito L, Beckman JS, Johnson GV., 1997, Nerve growth factor protects PC12 cells against peroxynitrite-induced apoptosis via a mechanism dependent on phosphatidylinositol 3-kinase. J Neurochem., 69:53-59.
22. Suzuki H, Terauchi Y, Fujiwara M, Aizawa S, Yazaki Y, Kadowaki T, Koyasu S., 1999, Xid-like immunodeficiency in mice with disruption of the p85oc subunit of phosphoinositide 3-kinase. Science., 283:390-392.
23. Ullrich A, Schlessinger J., 1990, Signal transduction by receptors with tyrosine kinase activity. Cell., 61:203-212.
24. White MF, Khan CR., 1994, The insulin signaling system. J Biol Chem., 269:1-4.
25. Williams LT., 1989, Signal transduction by the platelet-derived growth factor receptor. Science., 243:1564-1570.