Ortho Effects in Quantitative Structure Activity Relationships for Lipase Inhibition by Aryl Carbamates

QSAR and Combinatorial Science

Volumn 22, Issue 8, 2003, Pages 852-858

  Lin, Gialih ^a   Liu, Yue Chen ^a   Wu, Yon Gi ^a   Lee, Yu Ru ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Carbamate inhibitors; Cross interactions; Lipase inhibition; Ortho effects; QSAR

Indexed keywords

AMINO ACIDS; COMPUTATIONAL CHEMISTRY; DISSOCIATION; ENZYME INHIBITION;

CARBAMATE INHIBITOR; CARBAMYLATION; CROSS INTERACTIONS; LIPASE INHIBITIONS; ORTHO EFFECT; PHENYL SUBSTITUENTS; PROTONATED; QSAR; STERICS; TRANSITION STATE;

PROTONATION;

BACTERIAL ENZYME; CARBAMIC ACID DERIVATIVE; ENZYME INHIBITOR; HISTIDINE; PHENOL; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; TRIACYLGLYCEROL LIPASE;

ARTICLE; CARBAMOYLATION; CIS TRANS ISOMERISM; CONFORMATIONAL TRANSITION; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME MECHANISM; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTON TRANSPORT; PSEUDOMONAS; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS); CYGNUS; PSEUDOMONAS;

EID: 0346158261     PISSN: 1611020X     EISSN: None     Source Type: Journal    
DOI: 10.1002/qsar.200330827     Document Type: Article

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