-
1
-
-
0034930262
-
The relative power of SNPs and haplotype as genetic markers for association tests
-
Bader JS. 2001. The relative power of SNPs and haplotype as genetic markers for association tests. Pharmacogenomics 2(1):11-24.
-
(2001)
Pharmacogenomics
, vol.2
, Issue.1
, pp. 11-24
-
-
Bader, J.S.1
-
2
-
-
0026745610
-
Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
-
Citron M, Oltersdorf T, Haass C, McConlogue L, Hung AY, Seubert P, Vigo-Pelfrey C, Lieberburg I, Selkoe DJ. 1992. Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production. Nature 360(6405):672-674.
-
(1992)
Nature
, vol.360
, Issue.6405
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
3
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice
-
Citron M, Westaway D, Xia W, Carlson G, Diehl T, Levesque G, JohnsonWood K, Lee M, Seubert P, Davis A, Kholodenko D, Motter R, Sherrington R, Perry B, Yao H, Strome R, Lieberburg I, Rommens J, Kim S, Schenk D, Fraser P, St George Hyslop P, Selkoe DJ. 1997. Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nat Med 3(1):67-72.
-
(1997)
Nat Med
, vol.3
, Issue.1
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
JohnsonWood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St. George Hyslop, P.22
Selkoe, D.J.23
more..
-
4
-
-
0033237335
-
A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission
-
Clayton D. 1999. A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission. Am J Hum Genet 65(4):1170-1177.
-
(1999)
Am J Hum Genet
, vol.65
, Issue.4
, pp. 1170-1177
-
-
Clayton, D.1
-
5
-
-
0034641736
-
Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness
-
Drysdale CM, McGraw DW, Stack CB, Stephens JC, Judson RS, Nandabalan K, Arnold K, Ruano G, Liggett SB. 2000. Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness. Proc Natl Acad Sci USA 97(19):10483-10488.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.19
, pp. 10483-10488
-
-
Drysdale, C.M.1
McGraw, D.W.2
Stack, C.B.3
Stephens, J.C.4
Judson, R.S.5
Nandabalan, K.6
Arnold, K.7
Ruano, G.8
Liggett, S.B.9
-
6
-
-
0034703979
-
Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
-
Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Baker M, Adamson J, Ronald J, Blangero J, Hutton M, Younkin SG. 2000. Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Science 290(5500):2303-2304.
-
(2000)
Science
, vol.290
, Issue.5500
, pp. 2303-2304
-
-
Ertekin-Taner, N.1
Graff-Radford, N.2
Younkin, L.H.3
Eckman, C.4
Baker, M.5
Adamson, J.6
Ronald, J.7
Blangero, J.8
Hutton, M.9
Younkin, S.G.10
-
7
-
-
0023430504
-
Gametic disequilibrium measures: Proceed with caution
-
Hedrick PW. 1987. Gametic disequilibrium measures: Proceed with caution. Genetics 117(2):331-341.
-
(1987)
Genetics
, vol.117
, Issue.2
, pp. 331-341
-
-
Hedrick, P.W.1
-
8
-
-
4243215848
-
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
-
Holtzman DM, Bales KR, Tenkova T, Fagan AM, Parsadanian M, Sartorius LJ, Mackey B, Olney J, McKeel D, Wozniak D, Paul SM. 2000. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 97(6):2892-2897.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.6
, pp. 2892-2897
-
-
Holtzman, D.M.1
Bales, K.R.2
Tenkova, T.3
Fagan, A.M.4
Parsadanian, M.5
Sartorius, L.J.6
Mackey, B.7
Olney, J.8
McKeel, D.9
Wozniak, D.10
Paul, S.M.11
-
9
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G. 1996. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274(5284):99-102.
-
(1996)
Science
, vol.274
, Issue.5284
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
10
-
-
0034697214
-
Tau polymorphisms are not associated with Alzheimer's disease
-
Kwon JM, Nowotny P, Shah PK, Chakraverty S, Norton J, Morris JC, Goate AM. 2000. Tau polymorphisms are not associated with Alzheimer's disease. Neurosci Lett 284(1-2):77-80.
-
(2000)
Neurosci Lett
, vol.284
, Issue.1-2
, pp. 77-80
-
-
Kwon, J.M.1
Nowotny, P.2
Shah, P.K.3
Chakraverty, S.4
Norton, J.5
Morris, J.C.6
Goate, A.M.7
-
11
-
-
0034573026
-
Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimer's disease brains
-
Ledesma MD, Da Silva JS, Crassaerts K, Delacourte A, De Strooper B, Dotti CG. 2000. Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimer's disease brains. EMBO Rep 1(6):530-535.
-
(2000)
EMBO Rep
, vol.1
, Issue.6
, pp. 530-535
-
-
Ledesma, M.D.1
Da Silva, J.S.2
Crassaerts, K.3
Delacourte, A.4
De Strooper, B.5
Dotti, C.G.6
-
12
-
-
0001588586
-
Haplotype analysis in population-based association studies
-
Mander AP. 2001. Haplotype analysis in population-based association studies. Stata J 1(1):57-73.
-
(2001)
Stata J
, vol.1
, Issue.1
, pp. 57-73
-
-
Mander, A.P.1
-
13
-
-
0031588662
-
Genetic analysis of complex diseases
-
discussion 1329-1330
-
Muller-Myhsok B, Abel L. 1997. Genetic analysis of complex diseases. Science 275(5304):1328-1329; discussion 1329-1330.
-
(1997)
Science
, vol.275
, Issue.5304
, pp. 1328-1329
-
-
Muller-Myhsok, B.1
Abel, L.2
-
14
-
-
0034704197
-
Susceptibility locus for Alzheimer's disease on chromosome 10
-
Myers A, Holmans P, Marshall H, Kwon J, Meyer D, Ramic D, Shears S, Booth J, DeVrieze FW, Crook R, Hamshere M, Abraham R, Tunstall N, Rice F, Carty S, Lillystone S, Kehoe P, Rudrasingham V, Jones L, Lovestone S, Perez-Tur J, Williams J, Owen MJ, Hardy J, Goate AM. 2000. Susceptibility locus for Alzheimer's disease on chromosome 10. Science 290(5500):2304-2305.
-
(2000)
Science
, vol.290
, Issue.5500
, pp. 2304-2305
-
-
Myers, A.1
Holmans, P.2
Marshall, H.3
Kwon, J.4
Meyer, D.5
Ramic, D.6
Shears, S.7
Booth, J.8
DeVrieze, F.W.9
Crook, R.10
Hamshere, M.11
Abraham, R.12
Tunstall, N.13
Rice, F.14
Carty, S.15
Lillystone, S.16
Kehoe, P.17
Rudrasingham, V.18
Jones, L.19
Lovestone, S.20
Perez-Tur, J.21
Williams, J.22
Owen, M.J.23
Hardy, J.24
Goate, A.M.25
more..
-
15
-
-
18244407351
-
Full genome screen for Alzheimer disease: Stage II analysis
-
Myers A, Wavrant De-Vrieze F, Holmans P, Hamshere M, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, Ramic D, Knowles H, Morris JC, Williams N, Norton N, Abraham R, Kehoe P, Williams H, Rudrasingham V, Rice F, Giles P, Tunstall N, Jones L, Lovestone S, Williams J, Owen MJ, Hardy J, Goate A. 2002. Full genome screen for Alzheimer disease: Stage II analysis. Am J Med Genet 114(2):235-244.
-
(2002)
Am J Med Genet
, vol.114
, Issue.2
, pp. 235-244
-
-
Myers, A.1
Wavrant De-Vrieze, F.2
Holmans, P.3
Hamshere, M.4
Crook, R.5
Compton, D.6
Marshall, H.7
Meyer, D.8
Shears, S.9
Booth, J.10
Ramic, D.11
Knowles, H.12
Morris, J.C.13
Williams, N.14
Norton, N.15
Abraham, R.16
Kehoe, P.17
Williams, H.18
Rudrasingham, V.19
Rice, F.20
Giles, P.21
Tunstall, N.22
Jones, L.23
Lovestone, S.24
Williams, J.25
Owen, M.J.26
Hardy, J.27
Goate, A.28
more..
-
16
-
-
0028226045
-
Multiple instability-regulating sites in the 3′ untranslated region of the urokinase-type plasminogen activator mRNA
-
Nanbu R, Menoud PA, Nagamine Y. 1994. Multiple instability-regulating sites in the 3′ untranslated region of the urokinase-type plasminogen activator mRNA. Mol Cell Biol 14(7):4920-4928.
-
(1994)
Mol Cell Biol
, vol.14
, Issue.7
, pp. 4920-4928
-
-
Nanbu, R.1
Menoud, P.A.2
Nagamine, Y.3
-
17
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D, Eckman C, Jensen M, Song X, Citron M, Suzuki N, Bird TD, Hardy J, Hutton M, Kukull W, Larson E, Levy-Lahad E, Viitanen M, Peskind E, Poorkaj P, Schellenberg G, Tanzi R, Wasco W, Lannfelt L, Selkoe D, Younkin S. 1996. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat Med 2(8):864-870.
-
(1996)
Nat Med
, vol.2
, Issue.8
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
18
-
-
0033810469
-
Single nucleotide polymorphisms and the future of genetic epidemiology
-
Schork NJ, Fallin D, Lanchbury JS. 2000. Single nucleotide polymorphisms and the future of genetic epidemiology. Clin Genet 58(4):250-264.
-
(2000)
Clin Genet
, vol.58
, Issue.4
, pp. 250-264
-
-
Schork, N.J.1
Fallin, D.2
Lanchbury, J.S.3
-
19
-
-
0035950225
-
Clearing the brain's amyloid cobwebs
-
Selkoe DJ. 2001. Clearing the brain's amyloid cobwebs. Neuron 32(2):177-180.
-
(2001)
Neuron
, vol.32
, Issue.2
, pp. 177-180
-
-
Selkoe, D.J.1
-
20
-
-
0033788789
-
Tissue plasminogen activator requires plasminogen to modulate amyloid-beta neurotoxicity and deposition
-
Tucker HM, Kihiko-Ehmann M, Wright S, Rydel RE, Estus S. 2000. Tissue plasminogen activator requires plasminogen to modulate amyloid-beta neurotoxicity and deposition. J Neurochem 75(5):2172-2177.
-
(2000)
J Neurochem
, vol.75
, Issue.5
, pp. 2172-2177
-
-
Tucker, H.M.1
Kihiko-Ehmann, M.2
Wright, S.3
Rydel, R.E.4
Estus, S.5
-
21
-
-
0029969280
-
Characterization of single chain urokinase-type plasminogen activator with a novel amino-acid substitution in the kringle structure
-
Yoshimoto M, Ushiyama Y, Sakai M, Tamaki S, Hara H, Takahashi K, Sawasaki Y, Hanada K. 1996. Characterization of single chain urokinase-type plasminogen activator with a novel amino-acid substitution in the kringle structure. Biochem et Biophys Acta 1293:83-89.
-
(1996)
Biochem et Biophys Acta
, vol.1293
, pp. 83-89
-
-
Yoshimoto, M.1
Ushiyama, Y.2
Sakai, M.3
Tamaki, S.4
Hara, H.5
Takahashi, K.6
Sawasaki, Y.7
Hanada, K.8
|