Characterization of DNA binding and the cysteine rich region of SRE, a GATA factor in Neurospora crassa involved in siderophore synthesis

Biochemistry

Volumn 41, Issue 51, 2002, Pages 15288-15295

  Harrison, Kelly A ^b   Marzluf, George A ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; DNA SEQUENCES; ELECTROPHORESIS; FUNGI; GENES; IRON; MUTAGENESIS; PROTEINS; ZINC;

MOBILITY SHIFT;

DNA;

IRON; ORNITHINE; OXYGENASE; PROTEIN; PROTEIN SRE; REPRESSOR PROTEIN; SIDEROPHORE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA; UNCLASSIFIED DRUG; ZINC;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; DNA BINDING; DNA PROBE; DNA SEQUENCE; ELECTROPHORETIC MOBILITY; ENZYME ACTIVITY; HOMEOSTASIS; MUTAGENESIS; NEUROSPORA CRASSA; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REGULATORY MECHANISM; USTILAGO;

CYSTEINE; DNA PROBES; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FUNGAL PROTEINS; GATA TRANSCRIPTION FACTORS; MUTAGENESIS, SITE-DIRECTED; NEUROSPORA CRASSA; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; SIDEROPHORES; ZINC; ZINC FINGERS;

FUNGI; NEUROSPORA; NEUROSPORA CRASSA; USTILAGO;

EID: 0346037323     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0204995     Document Type: Article

References (21)

1. Fu, Y. H., and Marzluf, G. A. (1987) Characterization of nit-2, the major nitrogen regulatory gene of Neurospora crassa, Mol. Cell. Biol. 7, 1691-1696.
2. Ballario, P., Vittorioso, P., Magrelli, A., Talora, C., Cabibbo, A., and Macino, G. (1996) White collar-1, a central regulator of blue light responses in Neurospora, is a zinc finger protein, EMBO J. 15, 1650-1657.
3. Linden, H., and Macino, G. (1997) White collar 2, a partner in blue-light signal transduction, controlling expression of lightregulated genes in Neurospora crassa, EMBO J. 16, 98-109.
4. Crosthwaite, S. K., Dunlap, J. C., and Loros, J. J. (1997) Neurospora WC-1 and WC-2: Transcription, photoresponses, and the origin of circadian rhythmicity, Science 276, 763-769.
5. Feng, B., Haas, H., and Marzluf, G. A. (2000) ASD4, a new GATA factor of Neurospora crassa, displays sequence-specific DNA binding and functions in ascus and ascospore development, J. Biochem. 39, 11065-11073.
6. Zhou, L. W., Haas, H., and Marzluf, G. A. (1998) Isolation and characterization of a new gene, sre, which encodes a GATA-type regulatory protein that controls iron transport in Neurospora crassa, Mol. Gen. Genet. 259, 532-540.
7. Guerinot, M. L. (1994) Microbial iron transport, Annu. Rev. Microbiol. 148, 743-772.
8. Neilands, J. B. (1995) Siderophores: Structure and function of microbial iron transport compounds, J. Biol. Chem. 270, 26723-26726.
9. Mei, B., Budde, A. D., and Leong, S. A. (1993) sid1, a gene initiating siderophore biosynthesis in Ustilago maydis: Molecular characterization, regulation by iron, and role in phytopathogenicity, Proc. Natl. Acad. Sci. U.S.A. 90, 903-907.
10. Voisard, C., Wang, J., McEvoy, J. L., Xu, P., and Leong, S. A. (1993) urbs1, a gene regulating siderophore biosynthesis in Ustilago maydis, encodes a protein similar to the erythroid transcription factor GATA-1, Mol. Cell. Biol. 13, 7091-7100.
11. An, Z., Mei, B., Yuan, W. M., and Leong, S. A. (1997) The distal GATA sequences of the sid1 promoter of Ustilago maydis mediate iron repression of siderophore production and interact directly with Urbs1, a GATA family transcription factor, EMBO J. 16, 1742-1750.
12. Haas, H., Angermayr, K., and Stöffler, G. (1997) Molecular analysis of a Penicillium chrysogenum GATA factor encoding gene (sreP) exhibiting significant homology to the Ustilago maydis urbs1 gene, Gene 184, 33-37.
13. Haas, H., Zadra, I., Stöffler, G., and Angermayr, K. (1999) The Aspergillus nidulans GATA factor SREA is involved in regulation of siderophore biosynthesis and control of iron uptake, J. Biol. Chem. 274, 4613-4619.
14. Zhou, L. W., and Marzluf, G. A. (1999) Functional analysis of the two zinc fingers of SRE, a GATA-type factor that negatively regulates siderophore synthesis in Neurospora crassa, Biochemistry 38, 4335-4341.
15. Pan, T. P., Freedman, L. P., and Coleman, J. E. (1990) Cadmium-113 NMR studies of the DNA binding domain of the mammalian glucocorticoid receptor, Biochemistry 29, 9218-9225.
16. Frankel, A. D., Bredt, D. S., and Pabo, C. O. (1988) Tat protein from human immunodeficiency virus forms a metal-linked dimer, Science 240, 70-73.
17. Crossley, M., Merika, M., and Orkin, S. H. (1995) Self-association of the erythroid transcription factor GATA-1 mediated by its zinc finger domains. Mol. Cell. Biol. 15, 2448-256.
18. Merika, M., and Orkin, S. H. (1995) Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Kruppel family proteins Sp1 and EKLF, Mol. Cell. Biol. 15, 2437-2447.
19. Wolf, E., Kim, P. S., and Berger, B. (1997) MultiCoil: A program for predicting two- and three-stranded coiled coils, Protein Sci. 6, 1179-1189.
20. Feng, B., and Marzluf, G. A. (1998) Interaction between major nitrogen regulatory protein NIT2 and pathway-specific regulatory factor NIT4 is required for their synergistic activation of gene expression in Neurospora crassa, Mol. Cell. Biol. 18, 3983-3990.
21. Talora, C., Franchi, L., Linden, H., Ballario, P., and Macino, G. (1999) Role of a white collar-l-white color collar-2 complex in blue-light signal transduction. EMBO J. 18, 4961-4968.