메뉴 건너뛰기




Volumn 70, Issue 1, 1999, Pages 31-35

Tumor angiogenesis: Molecular facts and therapeutic opportunities;Tumorangiogenese: Molekulare Fakten und therapeutische Möglichkeiten

Author keywords

Anti angiogenic therapy; Oncology; Tumor angiogenesis; VEGF

Indexed keywords


EID: 0345823343     PISSN: 00094722     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001040050600     Document Type: Article
Times cited : (6)

References (20)
  • 1
    • 0030609013 scopus 로고    scopus 로고
    • Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells
    • Barleon B, Siemeister G, Martiny-Baron G, Weindel K, et al (1997) Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells. Cancer Res 57: 5421
    • (1997) Cancer Res , vol.57 , pp. 5421
    • Barleon, B.1    Siemeister, G.2    Martiny-Baron, G.3    Weindel, K.4
  • 2
    • 0031469819 scopus 로고    scopus 로고
    • Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
    • Boehm T, Folkman J, Browder T, O'Reilly MS (1997) Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 390: 404
    • (1997) Nature , vol.390 , pp. 404
    • Boehm, T.1    Folkman, J.2    Browder, T.3    O'Reilly, M.S.4
  • 3
    • 0027191251 scopus 로고
    • The endothelial-specific receptor tyrosine kinase tek is a member of a new subfamily of receptors
    • Dumont DJ, Gradwohl GJ, Fong GH, Auerbach R, Breitman ML (1993) The endothelial-specific receptor tyrosine kinase tek is a member of a new subfamily of receptors. Oncogene 8: 1293
    • (1993) Oncogene , vol.8 , pp. 1293
    • Dumont, D.J.1    Gradwohl, G.J.2    Fong, G.H.3    Auerbach, R.4    Breitman, M.L.5
  • 4
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N, Davis-Smyth T (1997) The biology of vascular endothelial growth factor. Endocr Rev 18: 4
    • (1997) Endocr Rev , vol.18 , pp. 4
    • Ferrara, N.1    Davis-Smyth, T.2
  • 5
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D, Folkman J (1996) Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353
    • (1996) Cell , vol.86 , pp. 353
    • Hanahan, D.1    Folkman, J.2
  • 6
    • 0032502843 scopus 로고    scopus 로고
    • Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor
    • Kong HL, Hecht D, Song W, Kovesdi I, et al (1998) Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor. Hum Gene Ther 9: 823
    • (1998) Hum Gene Ther , vol.9 , pp. 823
    • Kong, H.L.1    Hecht, D.2    Song, W.3    Kovesdi, I.4
  • 7
    • 0030800782 scopus 로고    scopus 로고
    • Up-regulation of flk-1/vascular endothelial growth factor receptor 2 by its ligand in a cerebral slice culture system
    • Kremer C, Breier G, Risau W, Plate KH (1997) Up-regulation of flk-1/vascular endothelial growth factor receptor 2 by its ligand in a cerebral slice culture system. Cancer Res 57: 3852
    • (1997) Cancer Res , vol.57 , pp. 3852
    • Kremer, C.1    Breier, G.2    Risau, W.3    Plate, K.H.4
  • 8
    • 0344705115 scopus 로고    scopus 로고
    • VEGF, Flk-1 and Flt-1 expression in a rat myocardial infarction model of angiogenesis
    • Li J, Brown LF, Hibberd MG, Grossman JD, et al (1996) VEGF, Flk-1 and Flt-1 expression in a rat myocardial infarction model of angiogenesis. Am J Physiol 270: 1803
    • (1996) Am J Physiol , vol.270 , pp. 1803
    • Li, J.1    Brown, L.F.2    Hibberd, M.G.3    Grossman, J.D.4
  • 9
    • 13144254247 scopus 로고    scopus 로고
    • Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie-2
    • Lin P, Buxton JA, Acheson A, Radziejewski C, et al (1998) Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie-2. Proc Natl Acad Sci USA 95: 8829
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8829
    • Lin, P.1    Buxton, J.A.2    Acheson, A.3    Radziejewski, C.4
  • 10
    • 0030726988 scopus 로고    scopus 로고
    • Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie-2 in pathologic vascular growth
    • Lin P, Polverini P, Dewhirst M, Shan S, et al (1997) Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie-2 in pathologic vascular growth. J Clin Invest 100: 2072
    • (1997) J Clin Invest , vol.100 , pp. 2072
    • Lin, P.1    Polverini, P.2    Dewhirst, M.3    Shan, S.4
  • 11
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
    • Millauer B, Shawver KL, Plate KH, Risau W, Ullrich A (1994) Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 367: 576
    • (1994) Nature , vol.367 , pp. 576
    • Millauer, B.1    Shawver, K.L.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 12
    • 0030890708 scopus 로고    scopus 로고
    • Manipulating angiogenesis: From basic science to the bedside
    • Pepper MS (1997) Manipulating angiogenesis: from basic science to the bedside. Arterioscler Thromb Vasc Biol 17: 605
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 605
    • Pepper, M.S.1
  • 13
    • 0008146577 scopus 로고    scopus 로고
    • Phase I trial of SU5416, a novel angiogenesis inhibitor, in patients with advanced malignancies
    • Rosen LS, Kabbinavar F, Rosen P, Mulay M, et al (1998) Phase I trial of SU5416, a novel angiogenesis inhibitor, in patients with advanced malignancies. Ann Oncol 9: 290
    • (1998) Ann Oncol , vol.9 , pp. 290
    • Rosen, L.S.1    Kabbinavar, F.2    Rosen, P.3    Mulay, M.4
  • 14
    • 0030029271 scopus 로고    scopus 로고
    • Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence
    • Saleh M, Stacker SA, Wilks AF (1996) Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence. Cancer Res 56: 393
    • (1996) Cancer Res , vol.56 , pp. 393
    • Saleh, M.1    Stacker, S.A.2    Wilks, A.F.3
  • 15
    • 0031870833 scopus 로고    scopus 로고
    • The pivotal role of VEGF in tumor angiogenesis: Molecular facts and therapeutic opportunities
    • Siemeister G, Martiny-Baron G, Marmé D (1998) The pivotal role of VEGF in tumor angiogenesis: Molecular facts and therapeutic opportunities. Cancer Metastasis Rev 17: 241
    • (1998) Cancer Metastasis Rev , vol.17 , pp. 241
    • Siemeister, G.1    Martiny-Baron, G.2    Marmé, D.3
  • 17
    • 0030480322 scopus 로고    scopus 로고
    • Requisite role of angiopoietin-1, a ligand for the Tie2 receptor, during embryonic angiogenesis
    • Suri C, Jones PF, Patan S, Bartunkova PC, et al (1996) Requisite role of angiopoietin-1, a ligand for the Tie2 receptor, during embryonic angiogenesis. Cell 87: 1171
    • (1996) Cell , vol.87 , pp. 1171
    • Suri, C.1    Jones, P.F.2    Patan, S.3    Bartunkova, P.C.4
  • 18
    • 0028940664 scopus 로고
    • Increased gene expression for VEGF and the VEGF receptor KDR/Flk and Flt in lungs exposed to acute or chronic hypoxia
    • Tuder RM, Flook BE, Voelkel NF (1995) Increased gene expression for VEGF and the VEGF receptor KDR/Flk and Flt in lungs exposed to acute or chronic hypoxia. J Clin Invest 95: 1798
    • (1995) J Clin Invest , vol.95 , pp. 1798
    • Tuder, R.M.1    Flook, B.E.2    Voelkel, N.F.3
  • 19
    • 0028935608 scopus 로고
    • Regulation by vascular endothelial growth factor of human colon cancer tumorigeneses in a mouse model of experimental liver metastasis
    • Warren RA, Yuan H, Matli MR, Gillett NA, Ferrara N (1995) Regulation by vascular endothelial growth factor of human colon cancer tumorigeneses in a mouse model of experimental liver metastasis. J Clin Invest 95: 1789
    • (1995) J Clin Invest , vol.95 , pp. 1789
    • Warren, R.A.1    Yuan, H.2    Matli, M.R.3    Gillett, N.A.4    Ferrara, N.5
  • 20
    • 0008108484 scopus 로고    scopus 로고
    • Pharmacological profile of a potent and orally active inhibitor of VEGF receptor kinases
    • Wood J, Buchdunger E, Cozens R, Hofman F, et al (1997) Pharmacological profile of a potent and orally active inhibitor of VEGF receptor kinases. Proc AACR: a255
    • (1997) Proc AACR
    • Wood, J.1    Buchdunger, E.2    Cozens, R.3    Hofman, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.