Targeted intracellular site-specific drug delivery: Photosensitizer targeting to melanoma cell nuclei

Russian Journal of Genetics

Volumn 39, Issue 2, 2003, Pages 198-206

  Rosenkranz, A A ^a,b   Lunin, V G ^a,c   Sergienko, O V ^c   Gilyazova, D G ^a,b   Voronina, O L ^c,d   Jans, D E ^e   Kofner, A A ^a,f   Shumiantseva, M A ^a,b   Mironov, A F ^f   Sobolev, A S ^a,b  

^a INSTITUTE OF GENE BIOLOGY   (Russian Federation)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c ALL RUSSIA RESEARCH INSTITUTE OF AGRICULTURAL BIOTECHNOLOGY   (Russian Federation)

^d BACH INSTITUTE OF BIOCHEMISTRY   (Russian Federation)

^e AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^f MIREA RUSSIAN TECHNOLOGICAL UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; BACTERIAL PROTEIN; DIPHTHERIA TOXIN; DRUG CARRIER; HEMOGLOBIN; OLIGOPEPTIDE; PHOTOSENSITIZING AGENT; RECOMBINANT PROTEIN; VIRUS T ANTIGEN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; DRUG TARGETING; ESCHERICHIA COLI; INTERNALIZATION; MELANOMA CELL; MOUSE; NONHUMAN; PHOTOTOXICITY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIMIAN VIRUS 40;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; SIMIAE; SIMIAN VIRUS 40;

EID: 0345798065     PISSN: 10227954     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022488027391     Document Type: Article

References (27)

1. Sobolev, A.S., Jans, D.A., and Rosenkranz, A.A., Targeted Intracellular Delivery of Photosensitizers, Progr. Biophys. Mol. Biol., 2000, vol. 73, pp. 51-90.
2. Rosenkranz, A.A., Jans, D.A., and Sobolev, A.S., Targeted Intracellular Delivery of Photosensitizers to Enhance Photodynamic Efficiency, Immunol. Cell Biol., 2000, vol. 78, pp. 452-464.
3. 6, Int. J. Cancer, 1999, vol. 81, pp. 734-740.
4. 6 Enhances Its Photosensitizing Activity, J. Biol. Chem., 1997, vol. 272, pp. 20328-20331.
5. 6 Photodynamic Activity in Vitro with Peptide-Based Intracellular Vehicles, Bioconjugate Chem., 1999, vol. 10, pp. 982-992.
6. Jiang, J., Sharma, S.D., Fink, J.L., et al., Melanotropic Peptide Receptors: Membrane Markers of Human Melanoma Cells., Exp. Dermatol., 1996, vol. 5, pp. 325-333.
7. Funasaka, Y., Sato, H., Chakraborty, A.K., et al., Expression of Proopiomelanocortin, Corticotropin-Releasing Hormone (CRH), and CRH Receptor in Melanoma Cells, Nevus Cells, and Normal Human Melanocytes, J. Invest. Dermatol. Symp. Proc., 1999, vol. 4, pp. 105-109.
8. Chen, J., Cheng, Z., Miao, Y., et al., A Melanocyte-Stimulating Hormone Peptide Analogs Labeled with Technetium-99m and Indium-11 for Malignant Melanoma Targeting, Cancer, 2002, vol. 94, pp. 1196-1201.
9. Mendelsohn, J. and Baselga, J., The EGF Family Receptors as Targets for Cancer Therapy, Oncogene, 2000, vol. 19, pp. 6550-6565.
10. Van Eijck, C.H., de Jong, M., Breeman, W.A., et al., Somatostatin Receptor Imaging and Therapy of Pancreatic Endocrine Tumors, Ann. Oncol., 1999, vol. 10, no. 4, pp. 177-181.
11. De Jong, M., Valkema, R., Jamar, F., et al., Somatostatin Receptor-Targeted Radionuclide Therapy of Tumors: Preclinical and Clinical Findings, Semin. Nucl. Med., 2002, vol. 32, pp. 133-140.
12. Plank, C., Oberhauser, B., Mechtler, K., et al., The Influence of Endosome-Disruptive Peptides on Gene Transfer Using Synthetic Virus-Like Gene Transfer Systems, J. Biol. Chem., 1994, vol. 269, pp. 12 918-12 924.
13. Siegrist, W. and Eberle, A., In Situ Melanin Assay for MSH Using Mouse B16 Melanoma Cells in Culture, Anal. Biochem., 1986, vol. 159, pp. 191-197.
14. O'Hare, K.B., Duncan, R., Strohalm, J., et al., Polymeric Drug-Carriers Containing Doxorubicin and Melanocyte-Stimulating Hormone: In Vitro and In Vivo Evaluation against Murine Melanoma, J. Drug Target., 1993, vol. 1, pp. 217-229.
15. 485 Results in the Formation of a Highly Potent Fusion Toxin Which Is Resistant to Proteolytic Degradation, J. Biol. Chem., 1991, vol. 266, pp. 12 289-12 993.
16. Mironov, A.F., Kozyrev, A.N., and Brandis, A., Sensitizers of Second Generation for Photodynamic Therapy of Cancer Based on Chlorophyll and Bacteriochlorophyll Derivatives, Proc. SPIE-Int. Soc. Opt. Eng., 1992, vol. 1922, pp. 204-208.
17. 124 Inhibits Nuclear Import of SV40 T-Antigen Proteins, J. Cell Biol., 1991, vol. 115, pp. 1203-1212.
18. 6His-Tagged Proteins, 2001, QIAGEN, 5th ed. http://www.qiagen.com/literature/handbooks/qxp/qxp/1016852QXPHB_0301WW.pdf.
19. Rosenkranz, A.A., Antonenko, Y.N., Smirnova, O.A., et al., Avian Adenovirus Induces Ion Channels in Model Bilayer Lipid Membranes, Biochem. Biophys. Res. Commun., 1997, vol. 236, pp. 750-753.
20. Hubner, S., Xiao, C.-Y., and Jans, D.A., The Protein Kinase CK2 Site (Ser 111/112) Enhances Recognition of the Simian Virus 40 Large T-Antigen Nuclear Localization Sequence by Importin, J. Biol. Chem., 1997, vol. 272, pp. 17 191-17 195.
21. 6, Cancer Res., 1995, vol. 55, pp. 1014-1019.
22. Finlay, G.J., Baguley, B.C., and Wilson, W.R., A Semiautomated Microculture Method for Investigating Growth Inhibitory Effects of Cytotoxic Compounds on Exponentially Growing Carcinoma Cells, Anal. Biochem., 1984, vol. 139, pp. 272-279.
23. Sahm, U.C., Olivier, G.W., Branch, S.K., et al., Influence of α-MSH Terminal Amino Acids on Binding Affinity and Biological Activity in Melanoma Cells, Peptides, 1994, vol. 15, pp. 441-446.
24. Uherek, C., Fominaya, J., and Wels, W., A Modular DNA Carrier Protein Based on the Structure of Diphtheria Toxin Mediates Target Cell-Specific Gene Delivery, J. Biol. Chem., 1998, vol. 273, pp. 8835-8841.
25. Nir, S. and Nieva, J.L., Interactions of Peptides with Liposomes: Pore Formation and Fusion, Progr. Lipid Res., 2000, vol. 39, pp. 181-206.
26. Ceresa, B.P. and Schmid, S.L., Regulation of Signal Transduction by Endocytosis, Curr. Opin. Cell Biol., 2000, vol. 12, pp. 204-210.
27. Chan, C.K. and Jans, D.A., Enhancement of MSH-Receptor- and GAL4-Mediated Gene Transfer by Switching the Nuclear Import Pathway, Gene Therapy, 2001, vol. 8, pp. 166-171.