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Volumn 71, Issue 12, 2003, Pages 7002-7013

Analysis of Virulence and Inflammatory Potential of Shigella flexneri Purine Biosynthesis Mutants

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0345714728     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.12.7002-7013.2003     Document Type: Article
Times cited : (38)

References (43)
  • 1
    • 0025366499 scopus 로고
    • Protection of adult rabbits and monkeys against shigellosis by oral immunization with a thymine-requiring and temperature-sensitive mutant of Shigella flexneri Y
    • Ahmed, Z. U., R. S. Mahfuzur, and D. A. Sack. 1990. Protection of adult rabbits and monkeys against shigellosis by oral immunization with a thymine-requiring and temperature-sensitive mutant of Shigella flexneri Y. Vaccine 8:153-158.
    • (1990) Vaccine , vol.8 , pp. 153-158
    • Ahmed, Z.U.1    Mahfuzur, R.S.2    Sack, D.A.3
  • 2
    • 0026625932 scopus 로고
    • icsB: A Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread
    • Allaoui, A., J. Mounier, M.-C. Prévost, P. J. Sansonetti, and C. Parsot. 1992. icsB: a Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread. Mol. Microbiol. 6:1605-1616.
    • (1992) Mol. Microbiol. , vol.6 , pp. 1605-1616
    • Allaoui, A.1    Mounier, J.2    Prévost, M.-C.3    Sansonetti, P.J.4    Parsot, C.5
  • 3
    • 0035063812 scopus 로고    scopus 로고
    • Attenuated Shigella flexneri 2a ΔguaBA strain CVD 1204 expressing enterotoxigenic Escherichia coli (ETEC) CS2 and CS3 fimbriae as a live mucosal vaccine against Shigella and ETEC infection
    • Altboum, Z., E. M. Barry, G. Losonsky, J. E. Galen, and M. M. Levine. 2001. Attenuated Shigella flexneri 2a ΔguaBA strain CVD 1204 expressing enterotoxigenic Escherichia coli (ETEC) CS2 and CS3 fimbriae as a live mucosal vaccine against Shigella and ETEC infection. Infect. Immun. 69:3150-3158.
    • (2001) Infect. Immun. , vol.69 , pp. 3150-3158
    • Altboum, Z.1    Barry, E.M.2    Losonsky, G.3    Galen, J.E.4    Levine, M.M.5
  • 4
    • 0033621856 scopus 로고    scopus 로고
    • ΔguaBA attenuated Shigella flexneri 2a strain CVD 1204 as a Shigella vaccine and as a live mucosal delivery system for fragment C of tetanus toxin
    • Anderson, R. J., M. F. Pasetti, M. B. Sztein, M. M. Levine, and F. R. Noriega. 2000. ΔguaBA attenuated Shigella flexneri 2a strain CVD 1204 as a Shigella vaccine and as a live mucosal delivery system for fragment C of tetanus toxin. Vaccine 18:2193-2202.
    • (2000) Vaccine , vol.18 , pp. 2193-2202
    • Anderson, R.J.1    Pasetti, M.F.2    Sztein, M.B.3    Levine, M.M.4    Noriega, F.R.5
  • 5
    • 0037449489 scopus 로고    scopus 로고
    • Immune responses elicited against multiple enterotoxigenic Escherichia coli fimbriae and mutant LT expressed in attenuated Shigella vaccine strains
    • Barry, E. M., Z. Altboum, G. Losonsky, and M. M. Levine. 2003. Immune responses elicited against multiple enterotoxigenic Escherichia coli fimbriae and mutant LT expressed in attenuated Shigella vaccine strains. Vaccine 21:333-340.
    • (2003) Vaccine , vol.21 , pp. 333-340
    • Barry, E.M.1    Altboum, Z.2    Losonsky, G.3    Levine, M.M.4
  • 6
    • 0035140011 scopus 로고    scopus 로고
    • Parameters underlying successful protection with live attenuated mutants in experimental shigellosis
    • Bernardini, M. L., J. Arondel, I. Martini, A. Aidara, and P. J. Sansonetti. 2001. Parameters underlying successful protection with live attenuated mutants in experimental shigellosis. Infect. Immun. 69:1072-1083.
    • (2001) Infect. Immun. , vol.69 , pp. 1072-1083
    • Bernardini, M.L.1    Arondel, J.2    Martini, I.3    Aidara, A.4    Sansonetti, P.J.5
  • 7
    • 0024362336 scopus 로고
    • Identification of icsA, a plasmid locus of Shigella flexneri that governs intra and intercellular spread through interaction with F-actin
    • Bernardini, M. L., J. Mounier, H. d'Hauteville, M. Coquis-Rondon, and P. J. Sansonetti. 1989. Identification of icsA, a plasmid locus of Shigella flexneri that governs intra and intercellular spread through interaction with F-actin. Proc. Natl. Acad. Sci. USA 86:3867-3871.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 3867-3871
    • Bernardini, M.L.1    Mounier, J.2    D'Hauteville, H.3    Coquis-Rondon, M.4    Sansonetti, P.J.5
  • 8
    • 0000182975 scopus 로고
    • XL1-Blue: A high efficiency plasmid transforming recA Escherichia coli strain with beta-galactosidase selection
    • Bullock, W. O., J. M. Fernandez, and J. M. Short. 1987. XL1-Blue: a high efficiency plasmid transforming recA Escherichia coli strain with beta-galactosidase selection. BioTechniques 5:376-378.
    • (1987) BioTechniques , vol.5 , pp. 376-378
    • Bullock, W.O.1    Fernandez, J.M.2    Short, J.M.3
  • 9
    • 0031932645 scopus 로고    scopus 로고
    • Intracellular multiplication and virulence of Shigella flexneri auxotrophic mutants
    • Cersini A., A. M. Salvia, and M. L. Bernardini. 1998. Intracellular multiplication and virulence of Shigella flexneri auxotrophic mutants. Infect. Immun. 66:549-557.
    • (1998) Infect. Immun. , vol.66 , pp. 549-557
    • Cersini, A.1    Salvia, A.M.2    Bernardini, M.L.3
  • 11
    • 0027532432 scopus 로고
    • Concentrations of interleukin 6 and tumor necrosis factor in serum and stools of children with Shigella dysenteriae I infection
    • de Silva, D. G., L. N. Mendis, N. Sheron, G. J. M. Alexander, D. C. A. Candy, H. Chart, and B. Rowe. 1993. Concentrations of interleukin 6 and tumor necrosis factor in serum and stools of children with Shigella dysenteriae I infection. Gut 34:194-198.
    • (1993) Gut , vol.34 , pp. 194-198
    • De Silva, D.G.1    Mendis, L.N.2    Sheron, N.3    Alexander, G.J.M.4    Candy, D.C.A.5    Chart, H.6    Rowe, B.7
  • 12
    • 0037094025 scopus 로고    scopus 로고
    • Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epithelium
    • d'Hauteville, H., S. Khan, D. J. Maskell, A. Kussak, A. Weintraub, J. Mathison, R. J. Ulevitch, N. Wuscher, C. Parsot, and P. J. Sansonetti. 2002. Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epithelium. J. Immunol. 168:5240-5251.
    • (2002) J. Immunol. , vol.168 , pp. 5240-5251
    • D'Hauteville, H.1    Khan, S.2    Maskell, D.J.3    Kussak, A.4    Weintraub, A.5    Mathison, J.6    Ulevitch, R.J.7    Wuscher, N.8    Parsot, C.9    Sansonetti, P.J.10
  • 13
    • 0026865190 scopus 로고
    • Single step elimination of contaminating DNA prior to reverse transcriptase PCR
    • Dilworth, D. D., and J. R. McCarrey. 1992. Single step elimination of contaminating DNA prior to reverse transcriptase PCR. PCR Methods Appl. 1:279-282.
    • (1992) PCR Methods Appl. , vol.1 , pp. 279-282
    • Dilworth, D.D.1    McCarrey, J.R.2
  • 14
    • 0002362974 scopus 로고
    • A chromosomal locus which controls the ability of Shigella flexneri to evoke keratoconjunctivitis
    • Formal, S. B., P. Gemsky, Jr., L. S. Baron, and E. H. LaBrec. 1971. A chromosomal locus which controls the ability of Shigella flexneri to evoke keratoconjunctivitis. Infect. Immun. 3:73-79.
    • (1971) Infect. Immun. , vol.3 , pp. 73-79
    • Formal, S.B.1    Gemsky Jr., P.2    Baron, L.S.3    LaBrec, E.H.4
  • 15
    • 0026091757 scopus 로고
    • Small animal model to measure efficacy and immunogenicity of Shigella vaccine strains
    • Hartman, A. B., C. Powell, C. L. Schultz, E. V. Oaks, and K. H. Eckels. 1991. Small animal model to measure efficacy and immunogenicity of Shigella vaccine strains. Infect. Immun. 59:4075-4083.
    • (1991) Infect. Immun. , vol.59 , pp. 4075-4083
    • Hartman, A.B.1    Powell, C.2    Schultz, C.L.3    Oaks, E.V.4    Eckels, K.H.5
  • 16
    • 0031864184 scopus 로고    scopus 로고
    • Type III protein secretion systems in bacterial pathogens of animals and plants
    • Hueek, C. J. 1998. Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol. Mol. Biol. Rev. 62:379-433.
    • (1998) Microbiol. Mol. Biol. Rev. , vol.62 , pp. 379-433
    • Hueek, C.J.1
  • 17
    • 0033849731 scopus 로고    scopus 로고
    • Attenuated Shigella flexneri 2a vaccine strain CVD 1204 expressing colonization factor antigen I and mutant heat-labile enterotoxin of enterotoxigenic Escherichia coli
    • Koprowski, H., II, M. M. Levine, R. J. Anderson, G. Losonsky, M. Pizza, and E. M. Barry. 2000. Attenuated Shigella flexneri 2a vaccine strain CVD 1204 expressing colonization factor antigen I and mutant heat-labile enterotoxin of enterotoxigenic Escherichia coli. Infect. Immun. 68:4884-4892.
    • (2000) Infect. Immun. , vol.68 , pp. 4884-4892
    • Koprowski II, H.1    Levine, M.M.2    Anderson, R.J.3    Losonsky, G.4    Pizza, M.5    Barry, E.M.6
  • 21
    • 0027518470 scopus 로고
    • Evaluation of Shigella vaccine safety and efficacy in an intranasal challenged mouse model
    • Mallett, C. P., L. L. Van De Verg, H. H. Collins, and T. L. Hale. 1993. Evaluation of Shigella vaccine safety and efficacy in an intranasal challenged mouse model. Vaccine 11:190-196.
    • (1993) Vaccine , vol.11 , pp. 190-196
    • Mallett, C.P.1    Van De Verg, L.L.2    Collins, H.H.3    Hale, T.L.4
  • 22
    • 0031015730 scopus 로고    scopus 로고
    • Shigella flexneri is trapped in polymorphonuclear leukocyte vacuoles and efficiently killed
    • Mandic-Mulec, I., J. Weiss, and A. Zychlinsky. 1997. Shigella flexneri is trapped in polymorphonuclear leukocyte vacuoles and efficiently killed. Infect. Immun. 65:110-115.
    • (1997) Infect. Immun. , vol.65 , pp. 110-115
    • Mandic-Mulec, I.1    Weiss, J.2    Zychlinsky, A.3
  • 23
    • 0027244956 scopus 로고
    • Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells
    • Menard, R., P. J. Sansonetti, and C. Parsot. 1993. Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells. J. Bacteriol. 175:5899-5906.
    • (1993) J. Bacteriol. , vol.175 , pp. 5899-5906
    • Menard, R.1    Sansonetti, P.J.2    Parsot, C.3
  • 25
    • 0028810845 scopus 로고
    • High-density presentation of an immunodominant minimal peptide on B cells is MHC-linked to Th1-like immunity
    • Murray, J. S., J. P. Kasselman, and T. Schountz. 1995. High-density presentation of an immunodominant minimal peptide on B cells is MHC-linked to Th1-like immunity. Cell. Immunol. 166:9-15.
    • (1995) Cell. Immunol. , vol.166 , pp. 9-15
    • Murray, J.S.1    Kasselman, J.P.2    Schountz, T.3
  • 26
    • 0034255209 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
    • Nathan, C., and M. U. Shiloh. 2000. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. Proc. Natl. Acad. Sci. USA 97:8841-8848.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8841-8848
    • Nathan, C.1    Shiloh, M.U.2
  • 27
    • 0029665144 scopus 로고    scopus 로고
    • Engineered ΔguaB-A ΔvirG Shigella flexneri 2a strain CVD 1205: Construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine
    • Noriega, F. R., G. Losonsky, C. Lauderbaugh, F. M. Liao, J. Y. Wang, and M. M. Levine. 1996. Engineered ΔguaB-A ΔvirG Shigella flexneri 2a strain CVD 1205: construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine. Infect. Immun. 64:3055-3061.
    • (1996) Infect. Immun. , vol.64 , pp. 3055-3061
    • Noriega, F.R.1    Losonsky, G.2    Lauderbaugh, C.3    Liao, F.M.4    Wang, J.Y.5    Levine, M.M.6
  • 28
    • 0029671022 scopus 로고    scopus 로고
    • Further characterization of ΔaroA ΔvirG Shigella flexneri 2A strain CVD 1203 as a mucosal Shigella vaccine and as a live-vector vaccine for delivering antigens of enterotoxigenic Escherichia coli
    • Noriega, F. R., G. Losonsky, J. Y. Wang, S. B. Formal, and M. M. Levine. 1996. Further characterization of ΔaroA ΔvirG Shigella flexneri 2A strain CVD 1203 as a mucosal Shigella vaccine and as a live-vector vaccine for delivering antigens of enterotoxigenic Escherichia coli. Infect. Immun. 64:23-27.
    • (1996) Infect. Immun. , vol.64 , pp. 23-27
    • Noriega, F.R.1    Losonsky, G.2    Wang, J.Y.3    Formal, S.B.4    Levine, M.M.5
  • 29
    • 0002574047 scopus 로고
    • Utilization of preformed purine bases and nucleosides
    • A. Munch-Petersen (ed.). Academic Press, Inc., London, United Kingdom
    • Nygaard, Y. 1983. Utilization of preformed purine bases and nucleosides, p. 27-93. In A. Munch-Petersen (ed.), Metabolism of nucleotides, nucleosides, and nucleobases in microorganisms. Academic Press, Inc., London, United Kingdom.
    • (1983) Metabolism of Nucleotides, Nucleosides, and Nucleobases in Microorganisms , pp. 27-93
    • Nygaard, Y.1
  • 30
    • 0029125457 scopus 로고
    • Monoclonal immunoglobulin A antibody directed against serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosis
    • Phalipon, A., M. Kaufmann, P. Michetti, J. M. Cavaillon, M. Huerre, P. J. Sansonetti, and J. P. Kraehenbuhl. 1995. Monoclonal immunoglobulin A antibody directed against serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosis. J. Exp. Med. 182:769-778.
    • (1995) J. Exp. Med. , vol.182 , pp. 769-778
    • Phalipon, A.1    Kaufmann, M.2    Michetti, P.3    Cavaillon, J.M.4    Huerre, M.5    Sansonetti, P.J.6    Kraehenbuhl, J.P.7
  • 31
    • 0034661989 scopus 로고    scopus 로고
    • Invasive Shigella flexneri activates NF-κB through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells
    • Philpott, D. J., S. Yamaoka, A. Israel, and P. J. Sansonetti. 2000. Invasive Shigella flexneri activates NF-κB through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells. J. Immunol. 165:903-914.
    • (2000) J. Immunol. , vol.165 , pp. 903-914
    • Philpott, D.J.1    Yamaoka, S.2    Israel, A.3    Sansonetti, P.J.4
  • 32
    • 0029080233 scopus 로고
    • Role of interleukin-1 in the pathogenesis of experimental shigellosis
    • Sansonetti, P. J., J. Arondel, J. M. Cavaillon, and M. Huerre. 1995. Role of interleukin-1 in the pathogenesis of experimental shigellosis. J. Clin. Investig. 96:884-892.
    • (1995) J. Clin. Investig. , vol.96 , pp. 884-892
    • Sansonetti, P.J.1    Arondel, J.2    Cavaillon, J.M.3    Huerre, M.4
  • 33
    • 0025884361 scopus 로고
    • ompB (osmo-regulation) and icsA (cell to cell spread) mutants of Shigella flexneri: Vaccine candidates and probes to study the pathogenesis of shigellosis
    • Sansonetti, P. J., J. Arondel, A. Fontaine, H. d'Hauteville, and M. L. Bernardini. 1991. ompB (osmo-regulation) and icsA (cell to cell spread) mutants of Shigella flexneri: vaccine candidates and probes to study the pathogenesis of shigellosis. Vaccine 9:416-422.
    • (1991) Vaccine , vol.9 , pp. 416-422
    • Sansonetti, P.J.1    Arondel, J.2    Fontaine, A.3    D'Hauteville, H.4    Bernardini, M.L.5
  • 34
    • 0033052681 scopus 로고    scopus 로고
    • Interleukin-8 controls bacterial transepithelial translocation at the cost of epithelial destruction in experimental shigellosis
    • Sansonetti, P. J., J. Arondel, M. Huerre, A. Harada, and K. Matsushima. 1999. Interleukin-8 controls bacterial transepithelial translocation at the cost of epithelial destruction in experimental shigellosis. Infect. Immun. 67:1471-1480.
    • (1999) Infect. Immun. , vol.67 , pp. 1471-1480
    • Sansonetti, P.J.1    Arondel, J.2    Huerre, M.3    Harada, A.4    Matsushima, K.5
  • 36
    • 0022630209 scopus 로고
    • Multiplication of Shigella flexneri within HeLa cells: Lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis
    • Sansonetti, P. J., A. Ryter, P. Clerc, A. T. Maurelli, and J. Mounier. 1986. Multiplication of Shigella flexneri within HeLa cells: lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis. Infect. Immun. 51:461-469.
    • (1986) Infect. Immun. , vol.51 , pp. 461-469
    • Sansonetti, P.J.1    Ryter, A.2    Clerc, P.3    Maurelli, A.T.4    Mounier, J.5
  • 37
    • 0030731851 scopus 로고    scopus 로고
    • Uptake of pathogenic intracellular bacteria into human and murine macrophages downregulates the eukaryotic 26S protease complex ATPase gene
    • Schwan, W. R., and D. J. Kopecko. 1997. Uptake of pathogenic intracellular bacteria into human and murine macrophages downregulates the eukaryotic 26S protease complex ATPase gene. Infect. Immun. 65:4754-4760.
    • (1997) Infect. Immun. , vol.65 , pp. 4754-4760
    • Schwan, W.R.1    Kopecko, D.J.2
  • 38
    • 0021027842 scopus 로고
    • A broad host range mobilization system for in vivo genetic engineering: Transposon mutagenesis in Gram negative bacteria
    • Simon, R., U. Priefer, and A. Puhler. 1983. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in Gram negative bacteria. Bio/Technology 1:784-791.
    • (1983) Bio/Tehcnology , vol.1 , pp. 784-791
    • Simon, R.1    Priefer, U.2    Puhler, A.3
  • 39
    • 0028966392 scopus 로고
    • Antibody and cytokine responses in a mouse pulmonary model of Shigella flexneri serotype 2a infection
    • van de Verg, L. L., C. P. Mallett, H. H. Collins, T. Larsen, C. Hammack, and T. L. Hale. 1995. Antibody and cytokine responses in a mouse pulmonary model of Shigella flexneri serotype 2a infection. Infect. Immun. 63:1947-1954.
    • (1995) Infect. Immun. , vol.63 , pp. 1947-1954
    • Van De Verg, L.L.1    Mallett, C.P.2    Collins, H.H.3    Larsen, T.4    Hammack, C.5    Hale, T.L.6
  • 40
    • 0026062241 scopus 로고
    • Construction of aromatic dependent Shigella flexneri 2a live vaccine candidate strains: Deletion mutations in the aroA and the aroD genes
    • Verma, N. K., and A. A. Lindberg. 1991. Construction of aromatic dependent Shigella flexneri 2a live vaccine candidate strains: deletion mutations in the aroA and the aroD genes. Vaccine 9:6-9.
    • (1991) Vaccine. , vol.9 , pp. 6-9
    • Verma, N.K.1    Lindberg, A.A.2
  • 43
    • 0026635783 scopus 로고
    • Shigella flexneri induces apoptosis in infected macrophages
    • Zychlinsky, A., M. C. Prevost, and P. J. Sansonetti. 1992. Shigella flexneri induces apoptosis in infected macrophages. Nature 358:167-169.
    • (1992) Nature , vol.358 , pp. 167-169
    • Zychlinsky, A.1    Prevost, M.C.2    Sansonetti, P.J.3


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