Analysis of Gene Expression Patterns in Human Postburn Hypertrophic Scars

Journal of Burn Care and Rehabilitation

Volumn 24, Issue 6, 2003, Pages 371-377

  Paddock, Heather N ^a   Schultz, Gregory S ^a   Baker, Henry V ^a   Varela, Juan Carlos ^a   Beierle, Elizabeth A ^a   Moldawer, Lyle L ^a   Mozingo, David W ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b PO Box 100286 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE 16; MATRIX PROTEIN; PLEIOTROPHIN; PROTEIN; RNA; THROMBOSPONDIN; THROMBOSPONDIN 4; UNCLASSIFIED DRUG;

ADULT; ALGORITHM; AMINO ACID SEQUENCE; ARTICLE; BIOPSY; BIOSYNTHESIS; BURN; CASE REPORT; CONTROLLED STUDY; DNA MICROARRAY; DNA PROBE; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETICS; HUMAN; HYPERTROPHIC SCAR; MALE; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PEDIATRICS; PRESCHOOL CHILD; RNA ISOLATION; SKIN BIOPSY; UNINDEXED SEQUENCE; UPREGULATION;

ADULT; BIOPSY; BURNS; CHILD, PRESCHOOL; CICATRIX, HYPERTROPHIC; DNA PROBES; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BIOSYNTHESIS;

EID: 0345687889     PISSN: 02738481     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.BCR.0000095508.96754.E0     Document Type: Article

References (19)

1. Nguyen H, Lim J, Dresner ML, Nixon B. Effect of local corticosteroids on early inflammatory function in surgical wound of rats. J Foot Ankle Surg 1998;37:313-8.
2. Ashcroft GS, Lei K, Jin W, et al. Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing. Nat Med 2000;6:1147-53.
3. Ono I, Gunji H, Zhang JZ, Maruyama K, Kaneko F. Studies on cytokines related to wound healing in donor site wound fluid. J Dermatol Sci 1995;10:241-5.
4. Albina JE, Mills CD, Henry WLJ, Caldwell MD. Temporal expression of different pathways of 1-arginine metabolism in healing wounds. J Immunol 1990;144:3877-80.
5. Imaizumi T, Nomura K, Hashimoto I, Sawada Y. Interleukin-1 levels in blister fluids of some skin diseases with blister formation. Clin Physiol Biochem 1990;8:179-83.
6. Arturson G. Pathophysiology of the burn wound. Ann Chir Gynaecol 1980;69:178-90.
7. Robert R, Meyer W, Bishop S, Rosenberg L, Murphy L, Blakeney P. Disfiguring burn scars and adolescent self-esteem. Burns 1999;25:581-5.
8. Polo M, Ko F, Busillo F, Cruse CW, Krizek TJ, Robson MC. The 1997 Moyer Award. Cytokine production in patients with hypertrophic burn scars. J Burn Care Rehabil 1997;18: 477-82.
9. Castagnoli C, Trombotto C, Ariotti S, et al. Expression and role of IL-15 in post-burn hypertropic scars. J Invest Dermatol 1999;113:238-45.
10. Haverstock BD. Hypertrophic scars and keloids. Clin Podiatr Med Surg 2001;18:147-59.
11. Alizadeh AA, Eisen MB, Davis RE, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000;403:503-11.
12. Eisen MB, Spellman PT, Brown PO, Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 1998;95:14863-8.
13. Varela JC, Goldstein MH, Baker HV, Schultz GS. Microarray analysis of gene expression patterns during healing of rat corneas after excimer laser photrefractive surgery. Invest Ophthal Vis Sci 2002;43:1772-82.
14. Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 2001;98:5116-21.
15. Niessen FB, Andriessen MP, Schalkwijk J, Visser L, Timens W. Keratinocyte-derived growth factors play a role in the formation of hypertrophic scars. J Pathol 2001;194:207-16
16. Tsou R, Cole JK, Nathens AB, et al. Analysis of hypertrophic and normal scar gene expression with cDNA microarrays. J Burn Care Rehabil 2000;21:541-50.
17. Chen YW, Zhao P, Borup R, Hoffman EP. Expression profiling in the muscular dystrophies: identification of novel aspects of molecular pathophysiology. J Cell Biol 2000;151:1321-36.
18. Narouz-Ott L, Maurer P, Nitsche DP, Smyth N, Paulsson M. Thrombospondin-4 binds specifically to both collagenous and non-collagenous extracellular matrix proteins via its C-terminal domains. J Biol Chem 2000;275:37110-7.
19. Seandel M, Noack-Kunnmann K, Zhu D, Aimes RT, Quigley JP. Growth factor-induced angiogenesis in vivo requires specific cleavage of fibrillar type I collagen. Blood 2001;97:2323-32.