-
2
-
-
0031841377
-
Cytochrome P450 2C9: An enzyme of major importance in human drug metabolism
-
Miners JO, Birkett DJ (1998) Cytochrome P450 2C9: an enzyme of major importance in human drug metabolism. Br J Clin Pharmacol 45:525-538
-
(1998)
Br J Clin Pharmacol
, vol.45
, pp. 525-538
-
-
Miners, J.O.1
Birkett, D.J.2
-
3
-
-
0037115525
-
Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450-metabolized drugs
-
Rogers JF, Nafziger AN, Bertino JS Jr (2002) Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450-metabolized drugs. Am J Med 113:746-750
-
(2002)
Am J Med
, vol.113
, pp. 746-750
-
-
Rogers, J.F.1
Nafziger, A.N.2
Bertino Jr., J.S.3
-
4
-
-
0037565623
-
Pharmacogenetics of oral anticoagulants
-
Daly AK, King BP (2003) Pharmacogenetics of oral anticoagulants. Pharmacogenetics 13:247-252
-
(2003)
Pharmacogenetics
, vol.13
, pp. 247-252
-
-
Daly, A.K.1
King, B.P.2
-
6
-
-
0036263813
-
Cytochrome P450 2C9 polymorphisms: A comprehensive review of the in- vitro and human data
-
Lee CR, Goldstein JA, Pieper JA (2002) Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data. Pharmacogenetics 12:251-263
-
(2002)
Pharmacogenetics
, vol.12
, pp. 251-263
-
-
Lee, C.R.1
Goldstein, J.A.2
Pieper, J.A.3
-
7
-
-
0033608466
-
Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
-
Aithal GP, Day CP, Kesteven PJ, Daly AK (1999) Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications. Lancet 353:717-719
-
(1999)
Lancet
, vol.353
, pp. 717-719
-
-
Aithal, G.P.1
Day, C.P.2
Kesteven, P.J.3
Daly, A.K.4
-
8
-
-
0028210729
-
Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9
-
Rettie AE, Wienkers LC, Gonzalez FJ, Trager WF, Korzekwa KR (1994) Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9. Pharmacogenetics 4:39-42
-
(1994)
Pharmacogenetics
, vol.4
, pp. 39-42
-
-
Rettie, A.E.1
Wienkers, L.C.2
Gonzalez, F.J.3
Trager, W.F.4
Korzekwa, K.R.5
-
9
-
-
0036214863
-
CYP2C9 polymorphism: Impact on tolbutamide pharmacokinetics and response
-
Miners J (2002) CYP2C9 polymorphism: impact on tolbutamide pharmacokinetics and response. Pharmacogenetics 12:91-92
-
(2002)
Pharmacogenetics
, vol.12
, pp. 91-92
-
-
Miners, J.1
-
10
-
-
0034978572
-
The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement
-
van der WJ, Steijns LS, van Weelden MJ, de Haan K (2001) The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement. Pharmacogenetics 11:287-291
-
(2001)
Pharmacogenetics
, vol.11
, pp. 287-291
-
-
Van Der, W.J.1
Steijns, L.S.2
Van Weelden, M.J.3
De Haan, K.4
-
11
-
-
0035171326
-
Early acenocoumarol overanticoagulation among cytochrome P450 2C9 poor metabolizers
-
Verstuyft C, Morin S, Robert A, Loriot MA, Beaune P, Jaillon P, Becquemont L (2001) Early acenocoumarol overanticoagulation among cytochrome P450 2C9 poor metabolizers. Pharmacogenetics 11:735-737
-
(2001)
Pharmacogenetics
, vol.11
, pp. 735-737
-
-
Verstuyft, C.1
Morin, S.2
Robert, A.3
Loriot, M.A.4
Beaune, P.5
Jaillon, P.6
Becquemont, L.7
-
12
-
-
0034762014
-
Cytochrome P4502C9 (CYP2C9) allele frequencies in Canadian Native Indian and Inuit populations
-
Gaedigk A, Casley WL, Tyndale RF, Sellers EM, Jurima-Romet M, Leeder JS (2001) Cytochrome P4502C9 (CYP2C9) allele frequencies in Canadian Native Indian and Inuit populations. Can J Physiol Pharmacol 79:841-847
-
(2001)
Can J Physiol Pharmacol
, vol.79
, pp. 841-847
-
-
Gaedigk, A.1
Casley, W.L.2
Tyndale, R.F.3
Sellers, E.M.4
Jurima-Romet, M.5
Leeder, J.S.6
-
13
-
-
0028861660
-
Detection of CYP2C9 polymorphism based on the polymerase chain reaction in Chinese
-
Wang SL, Huang J, Lai MD, Tsai JJ (1995) Detection of CYP2C9 polymorphism based on the polymerase chain reaction in Chinese. Pharmacogenetics 5:37-42
-
(1995)
Pharmacogenetics
, vol.5
, pp. 37-42
-
-
Wang, S.L.1
Huang, J.2
Lai, M.D.3
Tsai, J.J.4
-
16
-
-
0029658591
-
The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism
-
Sullivan-Klose TH, Ghanayem BI, Bell DA, Zhang ZY, Kaminsky LS, Shenfield GM, Miners JO, Birkett DJ, Goldstein JA (1996) The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism. Pharmacogenetics 6:341-349
-
(1996)
Pharmacogenetics
, vol.6
, pp. 341-349
-
-
Sullivan-Klose, T.H.1
Ghanayem, B.I.2
Bell, D.A.3
Zhang, Z.Y.4
Kaminsky, L.S.5
Shenfield, G.M.6
Miners, J.O.7
Birkett, D.J.8
Goldstein, J.A.9
-
17
-
-
0030858832
-
The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase
-
Crespi CL, Miller VP (1997) The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase. Pharmacogenetics 7:203-210
-
(1997)
Pharmacogenetics
, vol.7
, pp. 203-210
-
-
Crespi, C.L.1
Miller, V.P.2
-
18
-
-
0036914221
-
Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance
-
Scordo MG, Pengo V, Spina E, Dahl ML, Gusella M, Padrini R (2002) Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance. Clin Pharmacol Ther 72:702-710
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 702-710
-
-
Scordo, M.G.1
Pengo, V.2
Spina, E.3
Dahl, M.L.4
Gusella, M.5
Padrini, R.6
-
19
-
-
0032891790
-
Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele
-
Kidd RS, Straughn AB, Meyer MC, Blaisdell J, Goldstein JA, Dalton JT (1999) Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C9*3 allele. Pharmacogenetics 9:71-80
-
(1999)
Pharmacogenetics
, vol.9
, pp. 71-80
-
-
Kidd, R.S.1
Straughn, A.B.2
Meyer, M.C.3
Blaisdell, J.4
Goldstein, J.A.5
Dalton, J.T.6
-
20
-
-
0034042132
-
Genetic polymorphism of the CYP2C subfamily and excessive serum phenytoin concentration with central nervous system intoxication
-
Ninomiya H, Mamiya K, Matsuo S, Ieiri I, Higuchi S, Tashiro N (2000) Genetic polymorphism of the CYP2C subfamily and excessive serum phenytoin concentration with central nervous system intoxication. Ther Drug Monit 22:230-232
-
(2000)
Ther Drug Monit
, vol.22
, pp. 230-232
-
-
Ninomiya, H.1
Mamiya, K.2
Matsuo, S.3
Ieiri, I.4
Higuchi, S.5
Tashiro, N.6
-
21
-
-
0036797601
-
Contributions of CYP2D6, CYP2C9 and CYP2C19 to the biotransformation of E- and Z-doxepin in healthy volunteers
-
Kirchheiner J, Meineke I, Muller G, Roots I, Brockmoller J (2002) Contributions of CYP2D6, CYP2C9 and CYP2C19 to the biotransformation of E-and Z-doxepin in healthy volunteers. Pharmacogenetics 12:571-580
-
(2002)
Pharmacogenetics
, vol.12
, pp. 571-580
-
-
Kirchheiner, J.1
Meineke, I.2
Muller, G.3
Roots, I.4
Brockmoller, J.5
-
22
-
-
0036336114
-
Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2
-
Kirchheiner J, Meineke I, Freytag G, Meisel C, Roots I, Brockmoller J (2002) Enantiospecific effects of cytochrome P450 2C9 amino acid variants on ibuprofen pharmacokinetics and on the inhibition of cyclooxygenases 1 and 2. Clin Pharmacol Ther 72:62-75
-
(2002)
Clin Pharmacol Ther
, vol.72
, pp. 62-75
-
-
Kirchheiner, J.1
Meineke, I.2
Freytag, G.3
Meisel, C.4
Roots, I.5
Brockmoller, J.6
-
23
-
-
0036231580
-
Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers
-
Kirchheiner J, Brockmoller J, Meineke I, Bauer S, Rohde W, Meisel C, Roots I (2002) Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers. Clin Pharmacol Ther 71:286-296
-
(2002)
Clin Pharmacol Ther
, vol.71
, pp. 286-296
-
-
Kirchheiner, J.1
Brockmoller, J.2
Meineke, I.3
Bauer, S.4
Rohde, W.5
Meisel, C.6
Roots, I.7
-
24
-
-
0033816613
-
Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis
-
Aithal GP, Day CP, Leathart JB, Daly AK (2000) Relationship of polymorphism in CYP2C9 to genetic susceptibility to diclofenac-induced hepatitis. Pharmacogenetics 10:511-518
-
(2000)
Pharmacogenetics
, vol.10
, pp. 511-518
-
-
Aithal, G.P.1
Day, C.P.2
Leathart, J.B.3
Daly, A.K.4
|