Inhibition of N-acetyltransferase activity and gene expression in human colon cancer cell lines by diallyl sulfide

Food and Chemical Toxicology

Volumn 42, Issue 2, 2004, Pages 195-202

  Chung, J G ^a   Lu, H F ^b   Yeh, C C ^c   Cheng, K C ^d   Lin, S S ^e   Lee, J H ^c  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHENG HSIN REHABILITATION MEDICAL CENTER   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d JEN AI HOSPITAL   (Taiwan)

^e CHUNGTAI INST HLTH SCI TECHNOL   (Taiwan)

Author keywords

2 Aminofluorene; Diallyl sulfide (DAS); Human colon cancer cell lines; N Acetyltransferase

Indexed keywords

2 FLUORENYLAMINE; ACYLTRANSFERASE INHIBITOR; ALLYL SULFIDE; ANTINEOPLASTIC AGENT; ARYLAMINE ACETYLTRANSFERASE; MESSENGER RNA; ALLYL COMPOUND; CYTOCHROME P450; SULFIDE;

ACETYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; COLON CARCINOMA; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; WESTERN BLOTTING; COLON TUMOR; DRUG ANTAGONISM; ENZYMOLOGY; GARLIC; GENE EXPRESSION REGULATION; PHYTOTHERAPY; TUMOR CELL LINE;

ALLIUM; ALLIUM SATIVUM;

ALLYL COMPOUNDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ARYLAMINE N-ACETYLTRANSFERASE; BLOTTING, WESTERN; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYTOCHROME P-450 ENZYME SYSTEM; FLOW CYTOMETRY; GARLIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PHYTOTHERAPY; POLYMERASE CHAIN REACTION; RNA, MESSENGER; SULFIDES;

EID: 0345528148     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2003.08.015     Document Type: Article

References (38)

1. Badawi A.F., Stern S.J., Lang N.P., Kadlubar F.F. Cytochrome P-450 and acetyltransferase expression as biomarkers of carcinogen-DNA adduct levels and human cancer susceptibility. Prog. Clin. Biol. Res. 395:1996;109-140.
2. Barone F.E., Tonsey T.M. Isolation, purification, identification, synthesis and kinetics of activation of the anticandidal component of allium sativum and a hypothesis for its mode of action. Mycologia. 69:1977;793-825.
3. Belman S., Solomon T., Segal A., Block E., Barany G. Inhibition of soybean lipoxygenase and mouse skin tumor promotion by onion and garlic components. J. Biochem. Toxicol. 4:1989;151-160.
4. Blum M., Grant D.M., McBride W., Heim M., Myere U.A. Human arylamine N-acetyltransferase genes. isolation, chromosomal localization, and functional expression DNA Cell Biol. 9:1990;193-203.
5. Boullin D.J. Garlic. a platelet inhibitor Lancet. 1:1981;776-777.
6. Cartwright R.A., Glasham R.W., Rogers H.J., Ahmed R.A., Barham-Hall D., Higgens E., Kahn M.A. Role of N-acetyltransferase phenotype in bladder carcinogenesis. a pharmacogenetic epidemiological approach to bladder cancer Lancet. 2:1982;842-846.
7. Cavallito C.J., Buck J.S., Suter C.M. Allicin, the antibacterial principle of Allium sativum. II: determination of the chemical structure. J. Am. Chem. Soc. 66:1954;1952-1954.
8. Chen G.W., Chung J.G., Hsieh C.L., Lin J.G. Effects of the garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity in human colon tumour cells. Food Chem. Toxicol. 36:1998;761-770.
9. Chen G.W., Chung J.G., Ho H.C., Lin J.G. Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity in Klebsiella pneumoniae. J. Appl. Toxicol. 19:1999;75-81.
10. Chung J.G., Yeh K.T., Wu S.L., Chen G.W., Hsu N.Y., Ho H.C. Novel transmembrane GTPase of non-small cell lung cancer identified by mRNA differential display. Cancer Res. 61:2001;8873-8879.
11. Chung J.G., Chen G.W., Wu L.T., Chang H.L., Lin J.G., Yen C.C., Wang T.F. Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity in strains of Helicobacter pylori from peptic ulcer patients. AM J. Chin. Med. 26:1998;353-364.
12. Chung J.G. Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity in human bladder tumour cells. Drug Chem. Toxicol. 22:1999;343-358.
13. Dausch J.G., Nixon D.W. Garlic. a review of its relationship to malignant disease Preventive Med. 19:1990;346-361.
14. Ebisawa T., Deguchi T. Structure and restriction fragment length polymorphism of genes for human liver arylamine N-acetyltransferase. Biochem. Biophys. Res. Commun. 177:1991;1252-1257.
15. Einisto P., Watanabe M., Ishidate M., Nohmi T. Mutagenicity of 30 chemicals in S. typhimurium possessing different nitroreductase or O-acetyltransferase activities. Mutat. Res. 259:1991;95-102.
16. Ferriola P.C., Cody V., Middleton E. Jr. Protein kinase C inhibition by plant flavonoids. Kinetic mechanisms and structure-activity relationships. Biochem. Pharmacol. 15:1989;1617-1624.
17. Grant D.M., Blum M., Beer M., Meyer U.A. Monomorphic and polymorphic human arylamine N-acetyltransferase. a comparison of liver isozymes and expressed products of two cloned genes Mol. Pharmacol. 39:1991;184-191.
18. Hayes M.A., Roberts E., Safe S.H., Farber E., Cameron R.G. Influences of different polychlorinated biphenyls on cytocidal, mitoinhibitory, and nodule-selecting activities of N-2-fluorenylacetamide in rat liver. JNCI. 76:1986;683-690.
19. Hsia T.C., Chung J.G., Lu H.F., Ho H.C., Yang C.C., Lu K.H., Hung C.F. The effect of paclitaxel on 2-aminofluorene-DNA adducts formation and arylamine N-acetyltransferase activity and gene expression in human lung tumor cells (A549). Food Chem. Toxicol. 40:2002;697-703.
20. Ilett K.F., David B.M., Detchon P., Castledon W.M., Kwa R. Acetylator phenotype in colorectal carcinoma. Cancer Res. 47:1987;1466-1469.
21. Lai J.M., Chung J.G., Wang H.H., Chen G.W., Wu L.T., Tsai C.H. Human colon tumor arylamine N-acetyltransferase characterization. Med. J. CMCH. 2:1997;93-103.
22. Lang N.P., Chu D.Z.J., Hunter C.F., Kendall D.C., Flammang T.J., Kadlubar F.F. Role of aromatic amine acetyltransferase in human colorectal cancer. Arch. Surg. 121:1986;1259-1261.
23. Li Y.C., Hung C.F., Yeh F.T., Lin J.P., Chung J.G. Luteolin-inhibited arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human and mouse leukemia cells. Food Chem. Toxicol. 39:2002;641-647.
24. Minchin R.F., Reeves P.T., Teitel C.H., McManus M.E., Mojarrabi T., Ilett K.F., Kadlubar F.F. N-and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferase expressed in COS-1 cells. Biochem. Biophys. Res. Commun. 185:1992;839-844.
25. Moore G.S., Atkins R.D. The fungicidal and fungistatic effect of an aqueous garlic extract on medically important yeast like fungi. Mycologia. 69:1977;341-348.
26. Ohsako S., Deguchi T. Cloning and expression of cDNAs for polymorphic and monomorphic N-acetyltransferase from human liver. J. Biol. Chem. 265:1990;4630-4634.
27. Parker H.G., Evans A.E.Z. Epidemiology of aromatic amine cancers. Searle C.E. Chemical Carcinogens, second ed. ACS Monograph 182. 1982;277-302 American Chemical Society, Washington, DC.
28. Ponte P., Ng S.Y., Engel J., Gunning P., Kedes L. Evolutionary conservation in the untranslated regions of actin mRNAs. DNA sequence of a human beta-actin cDNA Nucleic Acids Res. 12:1984;1687-1696.
29. Reider M.J., Shear N.H., Kanee A., Tang B.K., Spielberg S.P. Prominence of slow acetylator phenotype among patients with sulfonamide hypersensitivity reactions. Clin. Pharmacol. Ther. 49:1991;13-17.
30. Robert-Thomson I.C., Ryan P., Khoo K.K., Hart W.J., McMichael A.J., Burtler R.N. Diet, acetylator phenotype, and risk of colorectal neoplasia. Lancet. 347:1996;1372-1374.
31. Smith G., Stanley L.A., Sim E., Strange R.C., Wolf C.R. Metabolic polymorphisms and cancer susceptibility. Cancer Surv. 25:1995;27-65.
32. Steinmetz K.A., Kushi L.H., Bostick R.M., Folsom A.R., Potter J.A. Vegetables, fruit, and colon cancer in the Iowa Women's health study. A. J. Epidemiol. 139:1994;1-15.
33. Su C.C., Chen G.W., Yeh C.C., Yang M.D., Hung C.F., Chung J.G. Luteolin induces N-acetylation and DNA adduct of 2-aminofluorene acompanying N-acetyltransferase activity and gene expression in human bladder cancer T24 cell line. Anticancer Res. 23:2003;355-362.
34. Sundaram S.G., Milner J.A. Impact of organosulfur components in garlic on canine mammary tumor cells in culture. Cancer Lett. 74:1993;85-90.
35. Thorgeirsson S.S., Glowinski I.B., McManus M.E. Metabolism, mutagenicity, carcinogenicity of aromatic amines. Hodgson J., Bend J., Philpot R.M. Reviews in Biochemical Toxicity, Vol. 6. 1983;349-386 Elsevier/North Holland Biomedical Press, New York.
36. Weber W.W. The Acetylator Genes and Drug Response. 1987;Oxford University Press, New York.
37. Weber W.W., Hein D.W. N-Acetylation pharmacogenetics. Pharmacol Rev. 37:1985;25-79.
38. Yeh C.C., Hung C.F., Wang W.L., Chung J.G. Kinetics of acetyl coenzyme A. arylamine N-acetyltrasferase from rapid and slow acetylator human benign prostatic hyperplasia tissues Urological Res. 29:2001;311-316.