Ketoprofen 75 mg qid versus acetaminophen 1000 mg qid for 3 days on swelling, pain, and other postoperative events after third-molar surgery

Journal of Clinical Pharmacology

Volumn 43, Issue 3, 2003, Pages 305-314

  Bjornsson G A ^a   Haanaes H R ^a   Skoglund, L A ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; EPINEPHRINE PLUS LIDOCAINE; KETOPROFEN; LOCAL ANESTHETIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PINEX; PLACEBO; UNCLASSIFIED DRUG;

ADULT; ANALGESIA; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DENTAL SURGERY; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MECHANISM; EDEMA; FATIGUE; FEMALE; FEVER; GASTROINTESTINAL SYMPTOM; HEADACHE; HUMAN; MALE; MOLAR TOOTH; MUSCLE STIFFNESS; NAUSEA; PAIN ASSESSMENT; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL; STOMACH PAIN; TOOTH DISEASE; TREATMENT OUTCOME; VERTIGO;

ACETAMINOPHEN; ADOLESCENT; ADULT; ANALGESICS, NON-NARCOTIC; ANTI-INFLAMMATORY AGENTS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; KETOPROFEN; MALE; MOLAR, THIRD; PAIN, POSTOPERATIVE; TIME FACTORS; TOOTH EXTRACTION;

EID: 0345505685     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/0091270002250603     Document Type: Article

References (40)

1. Mehlisch D, Frakes L, Cavaliere MB, Gelman M: Double-blind parallel comparison of single oral doses of ketoprofen, codeine, and placebo in patients with moderate to severe dental pain. J Clin Pharmacol 1984;24:486-492.
2. Seymour RA, Kelly PJ, Hawkesford JE: The efficacy of ketoprofen and paracetamol (acetaminophen) in postoperative pain after third molar surgery. Br J Clin Pharmacol 1996;41:581-585.
3. McGurk M, Robinson P, Rajayogeswaran V, De Luca M, Casini A, Artigas R, et al: Clinical comparison of dexketoprofen trometamol, ketoprofen, and placebo in postoperative dental pain. J Clin Pharmacol 1998;38(Suppl.):46S-54S.
4. Cooper SA, Berrie R, Cohn P: Comparison of ketoprofen, ibuprofen, and placebo in a dental surgery pain model. Adv Ther 1988;5:43-53.
5. Skoglund LA, Skjelbred P, Fyllingen G: Analgesic efficacy of acetaminophen 1000 mg, acetaminophen 2000 mg, and the combination of acetaminophen 1000 mg and codeine phosphate 60 mg versus placebo in acute postoperative pain. Pharmacotherapy 1991;11:364-369.
6. Skjelbred P, Løkken P: Paracetamol versus placebo: effects on post-operative course. Eur J Clin Pharmacol 1979;15:27-33.
7. Skjelbred P, Løkken P, Skoglund LA: Postoperative administration of acetaminophen to reduce swelling and other inflammatory events. Curr Ther Res 1984;35:377-385.
8. Guidelines for good clinical practice (GCP) for trials on pharmaceutical products. WHO Technical Report Series, No 850, Annex 3, 1995.
9. Owens WD, Felts JA, Spitznagel EL: ASA physical classifications: a study of consistency of ratings. Anesthesiology 1978;49:239-243.
10. Skjelbred P, Album B, Løkken P: Acetylsalicylic acid vs paracetamol: effects on postoperative course. Eur J Clin Pharmacol 1977;12:257-264.
11. Album B, Olsen I, Løkken P: Bilateral surgical removal of impacted third molar teeth as a model for drug evaluation: a test with oxyphenbutazone (Tanderil). Int J Oral Surg 1977;6:177-189.
12. Skoglund LA, Pettersen N: Effects of acetaminophen after bilateral oral surgery: double dose twice daily versus standard dose four times daily. Pharmacotherapy 1991;11:370-375.
13. Björnsson GA, Bjørnland T, Skoglund LA: Reproducability of postoperative courses after surgical removal of symmetrically impacted wisdom teeth. Meth Find Clin Exp Pharmacol 1995;17: 345-356.
14. Skjelbred P, Løkken P: Codeine added to paracetamol induced adverse effects but did not increase analgesia. Br J Clin Pharmacol 1982;14:539-543.
15. Breivik EK, Skoglund LA: Comparison of present pain intensity assessments on horizontally and vertically oriented visual analogue scales. Meth Find Clin Exp Pharmacol 1998;20:719-724.
16. Hepsø HU, Løkken P, Bjørnson J, Godal HC: Double-blind crossover study of the effect of acetylsalicylic acid on bleeding and postoperative course after bilateral oral surgery. Eur J Clin Pharmacol 1976; 10:217-225.
17. SPSS for Windows, version 8.0. Chicago: SPSS, 1997.
18. Pasila M, Michelsonn JE, Sundholm A: Anti-inflammatory chemotherapy in recent ankle and foot sprains. Br J Clin Pract 1980;6:78-86.
19. Mather LE: Do the pharmacodynamics of the nonsteroidal antiinflammatory drugs suggest a role in the management of postoperative pain? Drugs 1992;44(Suppl. 5):1-12.
20. Skoglund LA, Eidsaunet W, Pettersen N: The anti-oedematous efficacy of oxindanac equals that of paracetamol in acute postoperative inflammation: are weak cyclooxygenase inhibitors more effective than strong inhibitors? Int J Clin Pharm Res 1989;9:371-375.
21. McCormack K, Brune K: Dissociation between the antinociceptive and anti-inflammatory effects of the nonsteroidal anti-inflammatory drugs. Drugs 1991;41:533-547.
22. Vane JR, Ferreira SH (eds.): Handbook of Experimental Pharmacology: Inflammation. Heidelberg: Springer Verlag, 1978.
23. Skjelbred P, Løkken P: Post-operative pain and inflammatory reaction reduced by injection of a corticosteroid. Eur J Clin Pharmacol 1982;21:391-396.
24. Skjelbred P, Løkken P: Reduction of pain and swelling by a corticosteroid injection 3 hours after surgery. Eur J Clin Pharmacol 1982;15:141-146.
25. Skjelbred P, Løkken P: Effects of naloxone on post-operative pain and steroid-induced analgesia. Br J Clin Pharmacol 1983;15:221-226.
26. Olstad OA, Skjelbred P: Comparison of the analgesic effect of a corticosteroid and paracetamol in patients with pain after oral surgery. Br J Clin Pharmacol 1986;22:437-442.
27. Cooper SA, Gelb SB, Goldman EH: An analgesic relative potency assay comparing ketoprofen and aspirin in postoperative dental pain. Adv Ther 1984;1:410-418.
28. Sunshine A, Olson NZ, Zighelboim I, De Castro A: Ketoprofen, acetaminophen plus oxycodone, and acetaminophen in the relief of postoperative pain. Clin Pharmacol Ther 1993;54:546-555.
29. Laska EM, Sunshine A, Zighelboim I, Roure C, Marrero I, Wanderling J, Olson N: Effect of caffeine on acetaminophen analgesia. Clin Pharmacol Ther 1983;33:498-509.
30. Cooper SA, Reynolds DC, Reynolds B, Hersh EV: Analgesic efficacy and safety of (R)-ketoprofen in postoperative dental pain. J Clin Pharmacol 1998;38(Suppl.):11S-18S.
31. Lanza FL: Endoscopic studies of gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal anti-inflammatory agents. Am J Med 1984;77:19-24.
32. Henry D, Lim LL-Y, Rodriguez LAG, Gutthann SP, Carson JL, Griffin M, Savage R, et al: Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis. Br Med J 1996;312:1563-1566.
33. Lanza FL, Codispotti JR, Nelson EB: An endoscopic comparison of gastroduodenal injury with over-the-counter doses of ketoprofen and acetaminophen. Am J Gastroenterol 1998;93:1051-1054.
34. Willett LR, Carson JL, Strom BL: Epidemiology of gastrointestinal damage associated with nonsteroidal anti-inflammatory drugs. Drug Saf 1994;10:170-181.
35. Cronberg S, Wallmark E, Söderberg I: Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans. Scand J Haematol 1984:33:155-159.
36. Seymour RA, Williams FM, Oxley A, Ward A, Fearns M, Brighan K, et al: A comparative study of the effects of aspirin and paracetamol (acetaminophen) on platelet aggregation and bleeding time. Eur J Clin Pharmacol 1984;26:567-571.
37. Niemei T, Tanskanen P, Taxell C, Juvela S, Randell T, et al: Effects of nonsteroidal anti-inflammatory drugs on hemostasis in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg Anesthesiol 1999;11:188-194.
38. Stichtenroth DO, Tsikas D, Gutzki FM, Frolich JC: Effects of ketoprofen and ibuprofen on platelet aggregation and prostanoid formation in man. Eur J Clin Pharmacol 1996;51:231-234.
39. Hunt CA, Dunford PR: Acetaminophen. J Am Pharm Assoc 1977; 17:517-521.
40. Jamali F, Brocks DR: Clinical pharmacokinetics of ketoprofen and its enantiomers. Clin Pharmacokinet 1990;19:197-217.