Tethering of Apoptotic Cells to Phagocytes through Binding of CD47 to Src Homology 2 Domain-Bearing Protein Tyrosine Phosphatase Substrate-1

Journal of Immunology

Volumn 171, Issue 11, 2003, Pages 5718-5726

  Tada, Kazutoshi ^a   Tanaka, Masato ^a,b   Hanayama, Rikinari ^a   Miwa, Keiko ^a,c   Shinohara, Azusa ^d   Iwamatsu, Akihiro ^d   Nagata, Shigekazu ^a,c,e  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b RIKEN YOKOHAMA INSTITUTE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d KIRIN BREWERY CO LTD   (Japan)

^e OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD47 ANTIGEN; MONOCLONAL ANTIBODY; PHOSPHATIDYLSERINE; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; DENDRITIC CELL; EMBRYO; ENZYME SUBSTRATE; FEMALE; HUMAN; HUMAN CELL; LYMPHOMA CELL LINE; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PURIFICATION; SPLEEN CELL; SRC HOMOLOGY DOMAIN; THYMOCYTE;

EID: 0345447673     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.11.5718     Document Type: Article

References (52)

1. Jacobson, M. D., M. Weil, and M. C. Raff. 1997. Programmed cell death in animal development. Cell 88:347.
2. Vaux, D. L., and S. J. Korsmeyer. 1999. Cell death in development. Cell 96:245.
3. Nagata, S. 1997. Apoptosis by death factor. Cell 88:355.
4. Thomberry, N. A., and Y. Lazebnik. 1998. Caspases: enemies within. Science 281:1312.
5. Fischer, U., R. U. Janicke, and K. Schulze-Osthoff. 2003. Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death Differ. 10:76.
6. Nagata, S., H. Nagase, K. Kawane, N. Mukae, and H. Fukuyama. 2003. Degradation of chromosomal DNA during apoptosis. Cell Death Differ. 10:108.
7. Henson, P. M., D. L. Bratton, and V. A. Fadok. 2001. Apoptotic cell removal. Curr. Biol. 11:R795.
8. Savill, J., and V. Fadok. 2000. Corpse clearance defines the meaning of cell death. Nature 407:784.
9. Ogasawara, J., R. Watanabe-Fukunaga, M. Adachi, A. Matsuzawa, T. Kasugai. Y. Kitamura, N. Itoh, T. Suda, and S. Nagata. 1993. Lethal effect of the anti-Fas antibody in mice. Nature 364:806.
10. Platt, N., R. P. da Silva, and S. Gordon. 1998. Recognizing death: the phagocytosis of apoptotic cells. Trends Cell Biol. 8:365.
11. Fadok, V. A., D. R. Voelker, P. A. Campbell, J. J. Cohen, D. L. Bratton, and P. M. Henson. 1992. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148:2207.
12. Fadok, V. A., D. L. Bratton, S. C. Frasch, M. L. Warner, and P. M. Henson. 1998. The role of phosphatidylserine in recognition of apoptotic cells by phagocytes. Cell Death Differ. 5:551.
13. Somersan, S., and N. Bhardwaj. 2001. Tethering and tickling: a new role for the phosphatidylserine receptor. J. Cell Biol. 155:501.
14. Scott, R. S., E. J. McMahon, S. M. Pop, E. A. Reap, R. Caricchio, P. L. Cohen, H. S. Earp, and G. K. Matsushima. 2001. Phagocytosis and clearance of apoptotic cells is mediated by MER. Nature 411:207.
15. Hanayama, R., M. Tanaka, K. Miwa, A. Shinohara, A. Iwamatsu, and S. Nagata. 2002. Identification of a factor that links apoptotic cells to phagocytes. Nature 417:182.
16. Hoffmann, P. R., A. M. deCathelineau, C. A. Ogden, Y. Leverrier, D. L. Bratton, D. L. Daleke, A. J. Ridley, V. A. Fadok, and P. M. Henson. 2001. Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells. J. Cell Biol. 155:649.
17. Fujioka, Y., T. Matozaki, T. Noguchi, A. Iwamatsu, T. Yamao, N. Takahashi, M. Tsuda, T. Takada, and M. Kasuga. 1996. A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion. Mol. Cell. Biol. 16:6887.
18. Seiffert, M., C. Cant, Z. Chen, I. Rappold, W. Brugger, L. Kanz, E. J. Brown, A. Ullrich, and H. J. Buhring. 1999. Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47. Blood 94:3633.
19. Jiang, P., C. F. Lagenaur, and V. Narayanan. 1999. Integrin-associated protein is a ligand for the P84 neural adhesion molecule. J. Biol. Chem. 274:559.
20. McIlroy, D., M. Tanaka, H. Sakahira, H. Fukuyama, M. Suzuki, K.-I. Yamamura, Y. Ohsawa, Y. Uchiyama, and S. Nagata. 2000. An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes. Genes Dev. 14:549.
21. Watanabe-Fukunaga, R., C. I. Brannan, N. G. Copeland, N. A. Jenkins, and S. Nagata. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:314.
22. Sakahira, H., M. Enari, and S. Nagata. 1998. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391:96.
23. Tanaka, M., T. Suda, T. Takahashi, and S. Nagata. 1995. Expression of the functional soluble form of human Fas ligand in activated lymphocytes. EMBO J. 14:1129.
24. + dendritic cell subset selectively endocytoses dying cells in culture and in vivo. J. Exp. Med. 195:1289.
25. Morelli, A. E., A. T. Larregina, W. J. Shufesky, A. F. Zahorchak, A. J. Logar, G. D. Papworth, Z. Wang, S. C. Watkins, L. D. Falo, Jr., and A. W. Thomson. 2003. Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production. Blood 101:611.
26. Jensen, O. N., A. Podtelejnikov, and M. Mann. 1996. Delayed extraction improves specificity in database searches by matrix-assisted laser desorption/ionization peptide maps. Rapid Commun. Mass Spectrom. 10:1371.
27. Yamao, T., T. Matozaki, K. Amano, Y. Matsuda, N. Takahashi, F. Ochi, Y. Fujioka, and M. Kasuga. 1997. Mouse and human SHPS-1: molecular cloning of cDNAs and chromosomal localization of genes. Biochem. Biophys. Res. Commun. 231:61.
28. Murai, K., H. Murakami, and S. Nagata. 1998. Myeloid-specific transcriptional activation by murine myeloid zinc finger protein-2. Proc. Natl. Acad. Sci. USA 95:3461.
29. Kawane, K., H. Fukuyama, H. Yoshida, H. Nagase, Y. Ohsawa, Y. Uchiyama, T. Iida, K. Okada, and S. Nagata. 2003. Impaired thymic development in mouse embryos deficient in apoptotic DNA degradation. Nat. Immun. 4:138.
30. Ohki, K., and A. Nagayama. 1983. Cell hybrids between SV40-transformed macrophage cell lines and a Chinese hamster cell line: growth responsiveness and induction of colony-stimulating factor. J. Cell. Physiol. 114:291.
31. Oshima, K., A. R. Ruhul Amin, A. Suzuki, M. Hamaguchi, and S. Matsuda. 2002. SHPS-1, a multifunctional transmembrane glycoprotein. FEBS Lett. 519:1.
32. Adams, S., L. J. van der Laan, E. Vernon-Wilson, C. Renardel de Lavalette, E. A. Dopp, C. D. Dijkstra, D. L. Simmons, and T. K. van den Berg. 1998. Signal-regulatory protein is selectively expressed by myeloid and neuronal cells. J. Immunol. 161:1853.
33. Babic, I., A. Schallhorn, F. P. Lindberg, and F. R. Jirik. 2000. SHPS-1 induces aggregation of Ba/F3 pro-B cells via an interaction with CD47. J. Immunol. 164:3652.
34. Kawane, K., H. Fukuyama, G. Kondoh, J. Takeda, Y. Ohsawa, Y. Uchiyama, and S. Nagata. 2001. Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver. Science 292:1546.
35. Savill, J., I. Dransfield, C. Gregory, and C. Haslett. 2002. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat. Rev. Immunol. 2:965.
36. Fadok, V. A., A. de Cathelineau, D. L. Daleke, P. M. Henson, and D. L. Bratton. 2001. Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts. J. Biol. Chem. 276:1071.
37. Fadok, V. A., D. L. Bratton, D. M. Rose, A. Pearson, R. A. Ezekewitz, and P. M. Henson. 2000. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 405:85.
38. Oka, K., T. Sawamura, K. Kikuta, S. Itokawa, N. Kume, T. Kita, and T. Masaki. 1998. Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells. Proc. Natl. Acad. Sci. USA 95:9535.
39. Kawasaki, Y., A. Nakagawa, K. Nagaosa, A. Shiratsuchi, and Y. Nakanishi. 2002. Phosphatidylserine binding of class B scavenger receptor type 1, a phagocytosis receptor of testicular sertoli cells. J. Biol. Chem. 277:27559.
40. Gordon, S. 2003. Alternative activation of macrophages. Nat. Rev. Immunol. 3:23.
41. 3-dependent ligand binding. J. Cell Biol. 123:485.
42. Brown, E. J., L. Hooper, T. Ho, and H. D. Gresham. 1990. Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins. J. Cell Biol. 111:2785.
43. Rosales, C., H. D. Gresham, and E. J. Brown. 1992. Expression of the 50-kDa integrin-associated protein on myeloid cells and erythrocytes. J. Immunol. 149:2759.
44. Brown, E. J., and W. A. Frazier. 2001. Integrin-associated protein (CD47) and its ligand. Trends Cell Biol. 11:130.
45. Mateo, V., L. Lagneaux, D. Bron, G. Biron, M. Armant, G. Delespesse, and M. Sarfati. 1999. CD47 ligation induces caspase-independent cell death in chronic lymphocytic leukemia. Nat. Med. 5:1277.
46. Oldenborg, P. A., A. Zheleznyak, Y. F. Fang, C. F. Lagenaur, H. D. Gresham, and F. P. Lindberg. 2000. Role of CD47 as a marker of self on red blood cells. Science 288:2051.
47. Savill, J., I. Dransfield, N. Hogg, and C. Haslett. 1990. Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis. Nature 343:170.
48. Rebres, R. A., J. M. Green, M. I. Reinhold, M. Ticchioni, and E. J. Brown. 2001. Membrane raft association of CD47 is necessary for actin polymerization and protein kinase CO translocation in its synergistic activation of T cells. J. Biol. Chem. 276:7672.
49. Veillette, A., E. Thibaudeau, and S. Latour. 1998. High expression of inhibitory receptor SHPS-1 and its association with protein-tyrosine phosphatase SHP-1 in macrophages. J. Biol. Chem. 273:22719.
50. Voll, R. E., M. Herrmann, E. A. Roth, C. Stach, J. R. Kalden, and I. Girkontaite. 1997. Immunosuppressive effects of apoptotic cells. Nature 390:350.
51. Latour, S., H. Tanaka, C. Demeure, V. Mateo, M. Rubio, E. J. Brown, C. Maliszewski, F. P. Lindberg, A. Oldenborg, A. Ullrich, et al. 2001. Bidirectional negative regulation of human T and dendritic cells by CD47 and its cognate receptor signal-regulator protein-α: down-regulation of IL-12 responsiveness and inhibition of dendritic cell activation. J. Immunol. 167:2547.
52. Rigotti, A., S. L. Acton, and M. Krieger. 1995. The class B scavenger receptors SR-BI and CD36 are receptors for anionic phospholipids. J. Biol. Chem. 270:16221.