Analysis of the mechanism of action of the Brazilian type ( Aγ-195 C → G) of hereditary persistence of fetal hemoglobin

European Journal of Haematology

Volumn 71, Issue 6, 2003, Pages 418-424

  Takahashi, T ^a   Schreiber, R ^b   Krieger, J E ^b   Saad, S T O ^a   Costa, F F ^a,b  

^a Molec and Cell Biology Laboratory   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

195 C G gamma globin mutation; Electrophoretic mobility shift assay; Gene expression; Hereditary persistence of fetal hemoglobin; Sp1

Indexed keywords

ALPHA GLOBIN; GUANINE NUCLEOTIDE; HEMOGLOBIN F; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; PYRIMIDINE NUCLEOTIDE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL STRAIN; CONTROLLED STUDY; DNA STRUCTURE; EVALUATION; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION REGULATION; GENE LOCUS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REPORTER GENE;

BINDING SITES; BRAZIL; CELL LINE; CELL LINE, TRANSFORMED; DNA; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EMBRYO; FETAL HEMOGLOBIN; GENE EXPRESSION; GENES, REPORTER; GLOBINS; HEMOGLOBINOPATHIES; HUMANS; KIDNEY; LEUKEMIA, ERYTHROBLASTIC, ACUTE; LUCIFERASES; POINT MUTATION; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); SP1 TRANSCRIPTION FACTOR; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0345393119     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0902-4441.2003.00161.x     Document Type: Article

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